Abstract: A coupling point for a modular rotary which extends in an axial direction. The coupling point includes a first coupling part disposed on a tool head and a second coupling part disposed on a carrier. The coupling parts can be coupled to one another by bidirectional rotation with the formation of an interference fit which acts in the radial direction. Each coupling part includes two coupling faces which lie opposite one another and have contact regions in which the interference fit is formed. In the first coupling part, at least one of the coupling faces has at least two contact regions which are spaced apart from one another in the circumferential direction, and, to this end, at least one first clearance portion is formed between the contact regions, in which clearance portion the two coupling parts do not bear against one another in the coupled state.

Abstract: The mounting wrench (2) is used to engage or disengage a tool head (24) of a modular tool. The mounting wrench (2) incorporates a base body (4), which extends from an upper surface (20) along a centered longitudinal axis (18) to an underside (22). In addition, it has a slotted part (6), extending in the direction of the centered longitudinal axis (18), with a slot (10), into which the tool head (24) can be inserted. The slotted part (6) has two opposing keys (14), extending radially inward, which are each designed to mesh into a keyway (30) of the tool head (24). The keys (14) have a rounded end face (32), oriented radially inward, and are sloped relative to the centered longitudinal axis (18) so that the distance (a) between the keys (14) increases in the direction of the centered longitudinal axis (18).

Abstract: A twist drill includes a shank; a body adjacent the shank extending along a rotational, longitudinal axis of the twist drill, the body made of a carbide material; a plurality of helically extending chip flutes formed into the body with a web formed between the chip flutes, the chip flutes oriented at a helix angle relative to the longitudinal axis, each chip flute flanked by a major cutting edge with a corresponding flank or land and a minor cutting edge with a corresponding flank or land; and a ceramic insert attached to a notch formed in the body of the drill, wherein the ceramic insert forms only a portion of each of the major and minor cutting edges of the twist drill.

Abstract: The drill head (2) extends along a rotational axis (24) in the axial direction (22) and has a central area (6) on the front with first main cutting edges (26), an intermediate area (8) connecting thereto, and an outer area (10) in turn connecting thereto with second main cutting edges (30). The intermediate area (8) in this case expands in the axial direction (22) toward the outer area (10) and in particular forms an expanding conical shell. A centering effect is hereby achieved via the intermediate area (8).

Abstract: In order to ensure good guidance of a drilling tool at the start of a drilling operation and at the same time ensure a reliable evacuation of a center chip, in the drill bit, in a tool flank adjoining a respective main cutting edge, an additional point thinning is recessed in the region of a transverse cutting edge, which additional point thinning, extending in a principal direction from the tool flank, merges, with a convex course, into a chip flute. As a result of the convex design, an as far as possible homogeneous, edge-free transition into the chip flute is obtained. Since the point thinning is additionally made, the tool flank, even in the rear end facing away from the cutting edge, remains at a front axial position, so that a second land is effective for a reliable guidance of the bore already at an axially front position.

Abstract: The radial run-out tool (2), particularly a drill or a cutter, has a basic body (12) extending in an axial direction (4) and comprises at least two chip grooves (14), to which a guide chamfer (22) is connected in the rotational direction (24), with a ridge (15) being formed between them. A radial clearance is connected to the guide chamfer (22). In order to enable simple and economical production of such type of radial run-out tool (2), an unprocessed rod (30) is ground non-concentrically, in a first process step, such that a radius (R) of the unprocessed rod (30) varies, depending on the angle, between a maximum radius (R2) and a minimum radius (R1). In a second process step, the chip grooves (14) are grounded down such that the guide chamfers (22) are formed at the positions with the maximum radius (R2) and the radius (R) is subsequently reduced downstream of the respective guide chamfer (22) in order to form the radial clearance (28).

Abstract: Drill with a straight chucking groove, with a convexly curved main cutting edge with, adjacent to the main cutting edge, a convexly designed region of groove base and with, adjacent to the convexly designed region of the groove base, a concavely designed groove base or a concavely curved main cutting edge with, adjacent to the main cutting edge, a concavely designed groove base with, adjacent to the concavely design region of the groove base, a convexly design region of the groove base.

Abstract: A drilling/reaming tool includes a basic body which extends in a longitudinal direction. The basic body includes at least one end-side drilling major cutting edge, a main flute which is assigned to said drilling major cutting edge and is wound at a first helix angle, and a plurality of reaming cutting edges which are arranged circumferentially on the basic body and have in each case one reamer flute which is assigned to the respective reaming cutting edge and is wound at a second helix angle. The reaming cutting edges adjoin the at least one major cutting edge directly in the longitudinal direction. Each reamer flute is merged into the main flute.

Abstract: A tool head includes a main body having a nominal diameter, a face end center formed on the main body, and at least two major cutting edges which each run radially outward from and adjoin the face end center. The face end center is formed by a cone of circular cross-sectional area, which cone extends from a cone apex through to a cone base.

Abstract: In order to provide a rotary tool, in particular a drill, with a long service life together with high-quality drill holes, particularly in the case of through bores, the invention provides a cutting head which extends along a rotational axis and has a plurality of main cutting edges which extend radially outwards and each end at a cutting corner having a corner bevel, wherein the corner bevels are of differing designs, specifically in the form of a roughing bevel and in the form of a finishing bevel.

Abstract: A rotary cutting tool includes a generally cylindrical body having a first end, a second end and a longitudinal axis therebetween. A mounting portion is disposed about the first end, a head portion having an outer diameter is disposed about the second end, and a body relief portion having an outer diameter less than the head portion is disposed therebetween. The head portion is structured to engage and cut a workpiece. A number of flutes extend from the second end of the cylindrical body along the head portion and along at least a portion of the body relief portion. The head portion includes a number of margin relief surfaces, each disposed between adjacent flutes and inset a distance from the outer diameter of the head portion and extending from the second end of the cylindrical body and terminating at a margin seal within the head portion.

Abstract: A combination of a chucking device and a drill and a chucking device for a drill with cutting tips on both ends. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.

Abstract: A coupling point for a modular rotary which extends in an axial direction. The coupling point includes a first coupling part disposed on a tool head and a second coupling part disposed on a carrier. The coupling parts can be coupled to one another by bidirectional rotation with the formation of an interference fit which acts in the radial direction. Each coupling part includes two coupling faces which lie opposite one another and have contact regions in which the interference fit is formed. In the first coupling part, at least one of the coupling faces has at least two contact regions which are spaced apart from one another in the circumferential direction, and, to this end, at least one first clearance portion is formed between the contact regions, in which clearance portion the two coupling parts do not bear against one another in the coupled state.

Abstract: There is presented a detailed electronic method for simulation of a firefly, other insects, or organisms producing bioluminescence and with light radiation functions similar to a real firefly, other insects, or organisms producing bioluminescence. An illuminated artificial firefly, other insects, or organisms producing bioluminescence can be placed on trees and shrubs in landscape, or at home to produce radiation, at night time, and blinking a gradually decaying light. More particularly it relates to a decorative type of device in the form of a firefly, other insects, or organisms producing bioluminescence and with light radiation functions similar to a real firefly, other insects, or organisms producing bioluminescence. The light is simulated by an electronics program that is a part of compact device with the form of a real firefly, other insects, or organisms producing bioluminescence.

Abstract: A drilling/reaming tool includes a basic body which extends in a longitudinal direction. The basic body includes at least one end-side drilling major cutting edge, a main flute which is assigned to said drilling major cutting edge and is wound at a first helix angle, and a plurality of reaming cutting edges which are arranged circumferentially on the basic body and have in each case one reamer flute which is assigned to the respective reaming cutting edge and is wound at a second helix angle. The reaming cutting edges adjoin the at least one major cutting edge directly in the longitudinal direction. Each reamer flute is merged into the main flute.

Abstract: A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C1-4 alkyl, O, S, SO2, CO or CS and X1, X2, X3 and X4 are optionally substituted by 9 specific substituents or one can be nitrogen. Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I).

Abstract: The invention relates to a drill tip (2) comprising a base body (6) having chip flutes (22A,B) and extending in the axial direction along an axis of rotation (8) and having at least two main cutting edges (14A,B) on the front face thereof extending outward in the radial direction to a cutting corner (16A,B). Seen in cross section, the base body is asymmetric relative to rotation about the axis of rotation (8) at the height of the cutting corner (16A,B). The cross section of the base body is simultaneously designed having symmetrical spacing from the main cutting edges (14A,B). The drill tip (2) is in particular designed as an interchangeable modular part of a modularly designed drill tip (5). A drill base body (4) in which the drill tip (2) can be inserted can therefore in turn be designed symmetrically.

Abstract: A rotary cutting tool includes a generally cylindrical body having a first end, a second end and a longitudinal axis therebetween. A mounting portion is disposed about the first end, a head portion having an outer diameter is disposed about the second end, and a body relief portion having an outer diameter less than the head portion is disposed therebetween. The head portion is structured to engage and cut a workpiece. A number of flutes extend from the second end of the cylindrical body along the head portion and along at least a portion of the body relief portion. The head portion includes a number of margin relief surfaces, each disposed between adjacent flutes and inset a distance from the outer diameter of the head portion and extending from the second end of the cylindrical body and terminating at a margin seal within the head portion.

Abstract: There is presented a detailed electronic method for simulation of a firefly, other insects, or organisms producing bioluminescence and with light radiation functions similar to a real firefly, other insects, or organisms producing bioluminescence. An illuminated artificial firefly, other insects, or organisms producing bioluminescence can be placed on trees and shrubs in landscape, or at home to produce radiation, at night time, and blinking a gradually decaying light. More particularly it relates to a decorative type of device in the form of a firefly, other insects, or organisms producing bioluminescence and with light radiation functions similar to a real firefly, other insects, or organisms producing bioluminescence. The light is simulated by an electronics program that is a part of compact device with the form of a real firefly, other insects, or organisms producing bioluminescence.

Abstract: The present invention relates to the identification, isolation, and sequencing of a unique nucleic acid transcript termed Colon Cancer Associated Transcript 1 (CCAT-1) that is specifically expressed in cancer cells, in particular in colon, rectal, and lung cancer, as well as in precancerous lesions. The present invention thus provides methods for diagnosing cancer by detecting the expression of CCAT-1 as well as isolated polynucleotides, compositions and kits for use in the detection methods of the invention.