Patents by Inventor Herbert T. Nagasawa

Herbert T. Nagasawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that enhance the concentration of glutathione in tissues
    Patent number: 5624955
    Abstract: A pharmaceutical unit dosage form comprising an amount of a compound of the formula: ##STR1## is provided wherein R.sup.1 is a (C.sub.1 -C.sub.20)alkyl group, a (C.sub.6 -C.sub.12)aryl group, or a C.sub.3 -C.sub.18)cycloalkyl group and R.sup.2 is H or a (C.sub.1 -C.sub.19)alkyl group, a (C.sub.6 -C.sub.12)aryl group, a (C.sub.7 -C.sub.13)arylalkoxy group, a (C.sub.1 -C.sub.6)alkyoxy group, a (C.sub.3 -C.sub.18)cycloalkyl group, a ##STR2## group, or a --CH(R.sup.3)NH.sub.2 group wherein R.sup.3 is a side chain of a natural amino acid, and the pharmaceutically acceptable salts thereof; in combination with a pharmaceutically acceptable carrier, wherein said amount is effective to increase the concentration of glutathione in tissue.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: April 29, 1997
    Assignee: Regents of the University of Minnesota
    Inventors: Herbert T. Nagasawa, William B. Rathbun, Jonathan F. Cohen
  • Acylated cyanamide compounds
    Patent number: 4940816
    Abstract: Acylated cyanamide compounds useful for ethanol deterrence of the formula RCONHCN, wherein R is a lipophilic acyl group or is derived from an (N-substituted)-alpha-aminoacyl group.
    Type: Grant
    Filed: July 19, 1989
    Date of Patent: July 10, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Herbert T. Nagasawa, Chul-Hoon Kwon
  • Acylated cyanamide composition
    Patent number: 4870056
    Abstract: Acylated cyanamide compounds useful for ethanol deterrence of the formula RCONHCN, wherein R is a lipophilic acyl group or is derived from an (N-substituted)-alpha-aminoacyl group.
    Type: Grant
    Filed: October 21, 1987
    Date of Patent: September 26, 1989
    Assignee: Regents of the University of Minnesota
    Inventors: Herbert T. Nagasawa, Chul-Hoon Kwon
  • Method for elevating glutathione levels
    Patent number: 4868114
    Abstract: A method comprising stimulating the biosynthesis of glutathione in mammalian cells by contacting the cells with an effective amount of a compound of the formula: ##STR1## wherein R is a (CHOH).sub.n CH.sub.2 OH and wherein n is 1-5, preferably R is derived from a D-aldose monosaccharide.
    Type: Grant
    Filed: January 13, 1989
    Date of Patent: September 19, 1989
    Assignee: Regents of the University of Minnesota
    Inventors: Herbert T. Nagasawa, Jeanette C. Roberts
  • Acylated cyanamide composition for treating ethanol ingestion
    Patent number: 4726941
    Abstract: Acylated cyanamide compounds useful for ethanol deterrence of the formula RCONHCN, wherein R is a lipophilic acyl group or is derived from an (N-substituted)-alpha-aminoacyl group.
    Type: Grant
    Filed: January 23, 1986
    Date of Patent: February 23, 1988
    Assignee: Regents of the University of Minnesota
    Inventors: Herbert T. Nagasawa, Chul-Hoon Kwon