Abstract: An apparatus for swarm communication for an electric aircraft fleet, wherein the apparatus includes a plurality of electric aircraft connected by a mesh network. The apparatus further includes a computing device communicatively connected to the mesh network, wherein the computing device includes an authentication module configured to authenticate each electric aircraft and facilitate communication of a plurality of aircraft data between the plurality of electric aircraft. The computing device includes a plurality of communication components, each assigned to an electric aircraft of the electric aircraft fleet, wherein each communication component is configured to transmit the aircraft data to the communication component of its assigned electric aircraft. The apparatus further includes a cloud database configured to record the plurality of aircraft data.

Abstract: The invention relates to a method for controlling an orthopedic joint of a lower extremity in at least one degree of freedom by an adjustable actuator for adjusting an orthopedic apparatus to walking situations that differ from walking on a plane. The orthopedic apparatus includes a top connector connected to a limb and an orthopedic element that is arranged in a hinged manner distal to the top connector.

Abstract: A chuck includes a chuck surface, a plurality of vacuum ports being distributed over the chuck surface. Each of the vacuum ports is open to a conduit that is connectable to a suction source that is operable to apply suction to that vacuum port. A flow restrictor is located within each conduit and is characterized by a flow resistance. The flow resistance of the flow restrictor in at least one conduit is less than the flow resistance of the flow restrictor in at least one other conduit.

Abstract: In various embodiments, the present invention provides a drug-loaded amino acid-based poly(ester urea) film for controlled local release of non-opioid analgesic compounds and various methods for their making and use. In one or more embodiments, he present invention is directed to a drug-loaded amino acid-based poly(ester urea) film for controlled local release of non-opioid analgesic compounds comprising an amino acid-based poly(ester urea) polymer or copolymer and a therapeutically effective amount of a non-opioid analgesic compound. In various embodiments, these amino acid-based poly(ester urea) polymers or copolymers will comprise a plurality of diester monomer units connected by a carboxyl group to form a poly(ester urea) (PEU) polymer.

Abstract: Techniques discussed herein manage backups of a service cell (SC). Each SC may include a data plane that is isolated from other SCs and comprises a distributed computing cluster (a cluster). A manifest that specifies one or more backup policies may be used to generate a full backup or a partial backup of a data set stored by the cluster. In accordance with the manifest, a signal may be sent to nodes of the cluster. In response, the nodes may transmit locally-stored data (e.g., data segments) to specified locations at a remote storage. The system may maintain a mapping of which segments correspond to data that was stored in the cluster at a time corresponding to a full or partial backup.

Abstract: A system includes an exhaust diffuser system for a heat recovery steam generator (HRSG). The system includes an inlet portion, a diffuser portion axially extending from the inlet portion, and an outlet portion fluidly coupled to an axial distal end of the diffuser portion, wherein an outlet extent of the outlet portion is greater than an inlet extent of the inlet portion. The diffuser portion includes a plurality of wall portions, and the plurality of wall portions is incrementally angled relative to an axial extent extending from the inlet portion to the outlet portion. The system may further include a gas turbine engine coupled to the inlet portion and the HRSG.

Abstract: A system and method for landing an electric aircraft is provided. The system includes a controller, wherein the controller is communicatively connected to the sensor, wherein the controller is configured to, receive a plurality of measured flight data, determine a descent confirmation as a function of the plurality of measured flight data, generate a descent instruction set as a function of the descent confirmation and the plurality of measured flight data, wherein generating the descent instruction set further includes generating a transition instruction set, and transmit the descent instruction set to a plurality of flight components, wherein each flight component of the plurality of flight components are coupled to the electric aircraft.

Abstract: A method for producing an object by additive manufacturing including receiving in a process chamber a bath of material wherein a surface level of the bath of material defines an object working area, solidifying by a solidifying device a selective layer-part of the material on the surface level, and controlled oxidisation, of waste particles originating from the solidifying of the material, by controlling an oxygen level, such that oxidised waste particles are obtained and ignition of the waste particles is avoided. An apparatus for producing an objet by additive manufacturing.

Abstract: One embodiment of a method for rendering one or more graphics images includes tracing one or more rays through a graphics scene; computing one or more surface normals associated with intersections of the one or more rays with one or more surfaces, where computing each surface normal includes: computing a plurality of intermediate surface normals associated with a plurality of adjacent voxels of a grid, and interpolating the plurality of intermediate surface normals; and rendering one or more graphics images based on the one or more surface normals.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: An assembly includes elongated foamed elements that are arranged next to one another in one plane and bonded to one another at abutting side faces thereof, wherein the elongated foamed elements have been made by cutting at least one foamed sheet having a top and bottom surface, the at least one foamed sheet having been prepared by a foamed extrusion process and comprises a polymer composition including polypropylene, wherein the cutting is perpendicular to the top and bottom surfaces of the at least one foamed sheet, wherein the assembly has a top and bottom surface formed of surfaces of the elongated foamed elements perpendicular to the top or bottom surface of one of the at least one foamed sheet from which the respective elongated foamed element has been made, wherein the assembly is a sheet having a compression stress at yield in the thickness direction of at least 100 kPa.

Abstract: A watercraft includes a first pontoon slidably coupled to a second pontoon, at least one paddle coupled to the first pontoon, and at least one other paddle coupled to the second pontoon. A propulsion mechanism moves the paddles reciprocally when the pontoons move reciprocally relative to each other, with the paddles moving faster than the pontoons. The propulsion mechanism can include cables engaging pulleys carried by the pontoons, translating the reciprocating motion into paddle movement. The watercraft features paddle cavities on the undersides of the pontoons, housing paddle spacers and retaining rollers. A paddle retractor, such as a torsion spring, biases the paddles to retract when moving forward and deploy when moving rearward. A sliding connector with rollers ensures smooth reciprocal movement of the pontoons. Alternative propulsion mechanisms include racks and gears or belts and gears, optimizing the translation of reciprocating motion into forward thrust.

Abstract: In some embodiments, the present disclosure provides an exemplary method that may include steps of identifying a plurality of entities seeking to interact with each other; analyzing each entity to determine a type of constraint between each entity of the plurality of entities; automatically generating an internal identification token associated with each entity based on stored information; and utilizing the internal identification token to perform at least one action associated with the interaction of the plurality of entities.

Abstract: This invention relates to 4-substituted isoquinoline compounds and their derivatives and uses thereof for treatment of cancer, for example, acute myeloid leukemia.

Abstract: A computer includes a processor and a memory, and the memory stores instructions executable by the processor to identify personally identifiable information (PII) in an initial image frame; encode a region containing the PII of the initial image frame to a latent vector with a lower dimensionality than the region; anonymize the region from the initial image frame, resulting in a modified image frame; and associate the latent vector with the modified image frame.

Abstract: The invention lies in the field of treatment and prophylaxis of muscle wasting disorders, in particular the ones involving a genetic factor that can be targeted by a delivery of a therapeutic nucleic acid into the muscle cells. In line with the latter aspect, disclosed herein are pharmaceutical compositions and advantageous components thereof that substantially enhance the effective delivery and release of a therapeutic nucleic acid into the correct internal compartment of the muscle cell, such as the cytosol and/or the nucleus, in which compartment it can reach and act upon its genetic target. As disclosed herein, this substantially enhanced delivery and release is achieved by a provision of an endosomal-escape-enhancing saponin that is specifically targeted to muscle cells by covalent conjugation with a ligand of an endocytic receptor present on a muscle cell, into a pharmaceutical composition comprising a therapeutic nucleic acid.

Abstract: The present invention relates to spray drying plasma methodology that includes pretreating a donated liquid plasma unit, drying the liquid plasma using a spray drying apparatus with the spray drying disposable device that results in a disposable having the dried plasma, finishing the disposable using the finishing apparatus that is designed to seal and separate the disposable, and transform the disposable into a dried plasma unit. The methods of the present invention include storing the dried plasma unit and, when ready for use, reconstituting the dried plasma unit with reconstitution solution to obtain a plasma unit ready for transfusion into a recipient.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: A guard assembly includes a main body that is sized to fit around insulator bushing equipment and forms an opening, and a plurality of faceplates that are interchangeable to connect to the main body and cover at least a portion of the opening.

Abstract: A sole for a shoe, the sole comprising reinforcing members extending in a front half of the sole, wherein at least a first one of the reinforcing members further extends rearwardly beyond a midfoot area and into a heel area of the sole and wraps up to a posterior portion of an ankle region. A shoe, in particular a running shoe, comprising such a sole. A method for the manufacture of such items.