Patents by Inventor Hermanus Johannes Maria Kreuwel

Hermanus Johannes Maria Kreuwel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020127738
    Abstract: The present invention relates to a device for performing an assay, which device comprises a substrate having oriented through-going channels, said channels opening out on a surface for sample application, the channels in at least one area of the surface for sample application being provided with a first binding substance capable of binding to an analyte. The object of the present invention is to provide a substrate having both a high channel density and a high porosity, allowing high density arrays comprising different first binding substances to be applied to the surface for sample application. More in particular, the object of the present invention is to provide a device comprising a relatively cheap substrate that does not require the use of any typical microfabrication technology and, that offers an improved control over the liquid distribution over the surface of the substrate.
    Type: Application
    Filed: May 1, 2001
    Publication date: September 12, 2002
    Inventors: Hendrik Sibolt van Damme, Hermanus Johannes Maria Kreuwel
  • Publication number: 20020102565
    Abstract: The present invention relates to a device for performing an assay, which device comprises a substrate having oriented through-going channels, said channels opening out on a surface for sample application, the channels in at least one area of the surface for sample application being provided with a first binding substance capable of binding to an analyte. The object of the present invention is to provide a substrate having both a high channel density and a high porosity, allowing high density arrays comprising different first binding substances to be applied to the surface for sample application. More in particular, the object of the present invention is to provide a device comprising a relatively cheap substrate that does not require the use of any typical microfabrication technology and, that offers an improved control over the liquid distribution over the surface of the substrate.
    Type: Application
    Filed: April 30, 2001
    Publication date: August 1, 2002
    Applicant: PamGene B.V.
    Inventors: Hendrik Sibolt van Damme, Hermanus Johannes Maria Kreuwel
  • Patent number: 6225131
    Abstract: A device for performing an assay comprising a substrate having through-going channels that open out onto a surface for sample application, the channels being provided in at least one cross-sectional area with a first binding substance capable of binding a particular analyte, the substrate being an electrochemically manufactured metal oxide membrane and containing the first binding substance within the through-going channels.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: May 1, 2001
    Assignee: Akzo Nobel N.V.
    Inventors: Hendrik Sibolt van Damme, Hermanus Johannes Maria Kreuwel
  • Patent number: 6100966
    Abstract: A test device for bodily fluids comprising a solid carrier with a bonded reagent, a light source and a light detector. Light source and light detector are positioned is such a way that the majority of the light travels within the porous body along a transmission path, which is determined by scattering or reflection of the light within the porous body, until it arrives at the exit end where the transmitted light is measured.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: August 8, 2000
    Assignee: Akzo Nobel N.V.
    Inventor: Hermanus Johannes Maria Kreuwel