Patents by Inventor Hideaki Tahara
Hideaki Tahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9788441Abstract: A switching device includes a switching board with busbars, an upper case and stud bolts and nuts for fixing fastening terminals connected to wiring harnesses to the busbars. The upper case includes guide walls for guiding movements of the fastening terminals to fastening positions, and the restriction walls for restricting the rotation of the fastening terminals. The restriction walls are arranged to prevent a contact of the fastening terminal when the fastening terminal is rotated until the wiring harness comes into contact with the restriction wall.Type: GrantFiled: January 9, 2015Date of Patent: October 10, 2017Assignees: AutoNetworks Technologies, Ltd., Sumitomo Wiring Systems, Ltd., Sumitomo Electric Industries, Ltd.Inventors: Akira Haraguchi, Manabu Hashikura, Hideo Morikoka, Hideaki Tahara
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Publication number: 20170006703Abstract: A switching board is provided with a control circuit board including a control circuit, first mounting windows and second mounting windows, a circuit constituent including an input busbar, an output busbar and a connection busbar arranged on one surface of the control circuit board, and first and second semiconductor switching elements. The first semiconductor switching elements are arranged inside the first mounting windows and have drain terminals connected to the input busbar, source terminals connected to the connection busbar and gate terminals connected to the control circuit. The second semiconductor switching elements are arranged inside the second mounting windows and have drain terminals connected to the output busbar, source terminals connected to the connection busbar and gate terminals connected to the control circuit.Type: ApplicationFiled: January 9, 2015Publication date: January 5, 2017Inventors: Akira Haraguchi, Manabu Hashikura, Hideo Morioka, Hideaki Tahara
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Publication number: 20170006718Abstract: A switching device includes a switching board with busbars, an upper case and stud bolts and nuts for fixing fastening terminals connected to wiring harnesses to the busbars. The upper case includes guide walls for guiding movements of the fastening terminals to fastening positions, and the restriction walls for restricting the rotation of the fastening terminals. The restriction walls are arranged to prevent a contact of the fastening terminal when the fastening terminal is rotated until the wiring harness comes into contact with the restriction wall.Type: ApplicationFiled: January 9, 2015Publication date: January 5, 2017Inventors: Akira HARAGUCHI, Manabu HASHIKURA, Hideo MORIKOKA, Hideaki TAHARA
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Publication number: 20160264014Abstract: A switching board includes: a control circuit board that has, on a first surface thereof, a control circuit, a connection circuit, a first mounting window, and a second mounting window; a circuit structure including an input bus bar and an output bus bar are arranged on a second surface of the control circuit board; and a first and second semiconductor switching element. The first semiconductor switching element is arranged inside the first mounting window. The drain terminal, the source terminal, and the gate terminal of the first semiconductor switching element are connected respectively to the input bus bar, the connection circuit, and the control circuit. The second semiconductor switching element is arranged inside the second mounting window. The drain terminal, the source terminal, and the gate terminal of the second semiconductor switching element are connected respectively to the output bus bar, the connection circuit, and the control circuit.Type: ApplicationFiled: November 10, 2014Publication date: September 15, 2016Inventors: Akira HARAGUCHI, Manabu HASHIKURA, Hideo MORIOKA, Hideaki TAHARA
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Patent number: 9226934Abstract: The present invention is directed to an anti-cancer drug containing an anti-MFG-E8 antibody as an active ingredient, and to an anti-cancer drug which employs an anti-MFG-E8 antibody in combination with a cancer therapy employing an anti-cancer agent other than the anti-MFG-E8 antibody.Type: GrantFiled: April 28, 2009Date of Patent: January 5, 2016Assignee: THE UNIVERSITY OF TOKYOInventors: Hideaki Tahara, Masahisa Jinushi
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Publication number: 20140186381Abstract: The present invention provides immunogenic peptides comprising the amino acid sequence of SEQ ID NO: 1, 2, 13, 32, and peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted or added, and having cytotoxic T cell inducibility, and also provides drugs for treating or preventing tumors comprising these peptides. The peptides of this invention can be used as vaccines.Type: ApplicationFiled: January 21, 2014Publication date: July 3, 2014Applicant: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Takuya Tsunoda, Masabumi Shibuya, Shuichi Nakatsuru
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Patent number: 8674059Abstract: Objective methods for detecting and diagnosing colon cancer are described herein. In one embodiment, the diagnostic method involves determining the expression level of TOM34 that discriminates between colon cancer cells and normal cells. Finally, the present invention provides methods of screening for therapeutic agents useful in the treatment of colon cancer, methods of treating colon cancer and method for vaccinating a subject against colon cancer.Type: GrantFiled: July 21, 2006Date of Patent: March 18, 2014Assignee: Oncotherapy Science, Inc.Inventors: Yusuke Nakamura, Yoichi Furukawa, Hideaki Tahara, Takuya Tsunoda, Satoshi Matsushima
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Patent number: 8663647Abstract: The present invention provides immunogenic peptides comprising the amino acid sequence of SEQ ID NO: 1, 2, 13, 32, and peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted or added, and having cytotoxic T cell inducibility, and also provides drugs for treating or preventing tumors comprising these peptides. The peptides of this invention can be used as vaccines.Type: GrantFiled: August 3, 2012Date of Patent: March 4, 2014Assignee: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Takuya Tsunoda, Masabumi Shibuya, Shuichi Nakatsuru
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Patent number: 8642724Abstract: Objective methods for detecting and diagnosing colon cancer are described herein. In one embodiment, the diagnostic method involves determining the expression level of TOM34 that discriminates between colon cancer cells and normal cells. Finally, the present invention provides methods of screening for therapeutic agents useful in the treatment of colon cancer, methods of treating colon cancer and method for vaccinating a subject against colon cancer.Type: GrantFiled: July 21, 2006Date of Patent: February 4, 2014Assignee: Oncotherapy Science, Inc.Inventors: Yusuke Nakamura, Yoichi Furukawa, Hideaki Tahara, Takuya Tsunoda, Satoshi Matsushima
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Patent number: 8614176Abstract: The present invention provides peptides comprising the amino acid sequence of SEQ ID NO: 8, 67, 89, as well as peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted, deleted, or added, and having cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing tumors comprising these peptides. The peptides of the present invention can also be used as vaccines.Type: GrantFiled: October 13, 2010Date of Patent: December 24, 2013Assignee: OncoTherapy Science, Inc.Inventors: Hideaki Tahara, Takuya Tsunoda, Yusuke Nakamura, Yataro Daigo, Shuichi Nakatsuru
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Patent number: 8574585Abstract: The present invention provides nonapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:2, 3, 5, 8, 11, or 12; nonapeptides or decapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:29, 30, 33, 34, 40, or 46; and peptides with cytotoxic T cell inducibility, in which one, two, or several amino acids are substituted or added to the above-mentioned amino acid sequences, as well as pharmaceuticals for treating or preventing tumors, where the pharmaceuticals comprise these peptides. The peptides of this invention can be used as vaccines.Type: GrantFiled: June 12, 2012Date of Patent: November 5, 2013Assignee: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Satoshi Wada, Takuya Tsunoda
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Patent number: 8574586Abstract: The present invention provides nonapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:2, 3, 5, 8, 11, or 12; nonapeptides or decapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:29, 30, 33, 34, 40, or 46; and peptides with cytotoxic T cell inducibility, in which one, two, or several amino acids are substituted or added to the above-mentioned amino acid sequences, as well as pharmaceuticals for treating or preventing tumors, where the pharmaceuticals comprise these peptides. The peptides of this invention can be used as vaccines.Type: GrantFiled: June 12, 2012Date of Patent: November 5, 2013Assignee: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Satoshi Wada, Takuya Tsunoda
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Publication number: 20130071430Abstract: It is intended to provide a vaccinia virus that specifically proliferates in a cancer cell and destroys the cancer cell and to provide use of the virus in cancer treatment. The present invention provides a microRNA-controlled vaccinia virus, in which a target sequence of a microRNA less expressed in a cancer cell than in a normal cell is inserted in a 3? untranslated region of B5R gene associated with viral proliferation in a vaccinia virus, wherein the microRNA-controlled vaccinia virus specifically proliferates in the cancer cell and has an oncolytic property that destroys the cancer cell.Type: ApplicationFiled: March 15, 2011Publication date: March 21, 2013Applicant: THE UNIVERSITY OF TOKYOInventors: Takafumi Nakamura, Mina Hikichi, Hideaki Tahara, Hisatoshi Shida, Minoru Kidokoro
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Publication number: 20130028923Abstract: The present invention provides nonapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:2, 3, 5, 8, 11, or 12; nonapeptides or decapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:29, 30, 33, 34, 40, or 46; and peptides with cytotoxic T cell inducibility, in which one, two, or several amino acids are substituted or added to the above-mentioned amino acid sequences, as well as pharmaceuticals for treating or preventing tumors, where the pharmaceuticals comprise these peptides. The peptides of this invention can be used as vaccines.Type: ApplicationFiled: June 12, 2012Publication date: January 31, 2013Applicant: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Satoshi Wada, Takuya Tsunoda
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Publication number: 20120328636Abstract: The present invention provides nonapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:2, 3, 5, 8, 11, or 12; nonapeptides or decapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:29, 30, 33, 34, 40, or 46; and peptides with cytotoxic T cell inducibility, in which one, two, or several amino acids are substituted or added to the above-mentioned amino acid sequences, as well as pharmaceuticals for treating or preventing tumors, where the pharmaceuticals comprise these peptides. The peptides of this invention can be used as vaccines.Type: ApplicationFiled: June 12, 2012Publication date: December 27, 2012Applicant: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Satoshi Wada, Takuya Tsunoda
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Publication number: 20120294877Abstract: The present invention provides immunogenic peptides comprising the amino acid sequence of SEQ ID NO: 1, 2, 13, 32, and peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted or added, and having cytotoxic T cell inducibility, and also provides drugs for treating or preventing tumors comprising these peptides. The peptides of this invention can be used as vaccines.Type: ApplicationFiled: August 3, 2012Publication date: November 22, 2012Applicant: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Takuya Tsunoda, Masabumi Shibuya, Shuichi Nakatsuru
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Patent number: 8257711Abstract: The present invention provides immunogenic peptides comprising the amino acid sequence of SEQ ID NO: 1, 2, 13, 32, and peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted or added, and having cytotoxic T cell inducibility, and also provides drugs for treating or preventing tumors comprising these peptides. The peptides of this invention can be used as vaccines.Type: GrantFiled: March 3, 2011Date of Patent: September 4, 2012Assignee: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Takuya Tsunoda, Masabumi Shibuya, Shuichi Nakatsuru
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Publication number: 20120190628Abstract: The present application provides novel human genes RNF43 whose expression is markedly elevated in colorectal cancers, as well as CXADRL1 and GCUD1 whose expression is markedly elevated in gastric cancers compared to corresponding non-cancerous tissues. The genes and polypeptides encoded by the genes can be used, for example, in the diagnosis of a cell proliferative disease, and as target molecules for developing drugs against the disease.Type: ApplicationFiled: October 22, 2010Publication date: July 26, 2012Applicant: Oncotherapy Science, Inc.Inventors: Yusuke Nakamura, Yoichi Furukawa, Hideaki Tahara, Takuya Tsunoda
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Patent number: 8206719Abstract: The present invention provides nonapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:2, 3, 5, 8, 11, or 12; nonapeptides or decapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:29, 30, 33, 34, 40, or 46; and peptides with cytotoxic T cell inducibility, in which one, two, or several amino acids are substituted or added to the above-mentioned amino acid sequences, as well as pharmaceuticals for treating or preventing tumors, where the pharmaceuticals comprise these peptides. The peptides of this invention can be used as vaccines.Type: GrantFiled: February 23, 2010Date of Patent: June 26, 2012Assignee: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Satoshi Wada, Takuya Tsunoda
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Publication number: 20110250219Abstract: The present invention provides immunogenic peptides comprising the amino acid sequence of SEQ ID NO: 1, 2, 13, 32, and peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted or added, and having cytotoxic T cell inducibility, and also provides drugs for treating or preventing tumors comprising these peptides. The peptides of this invention can be used as vaccines.Type: ApplicationFiled: March 3, 2011Publication date: October 13, 2011Applicant: Oncotherapy Science, Inc.Inventors: Hideaki Tahara, Takuya Tsunoda, Masabumi Shibuya, Shuichi Nakatsuru