Abstract: The copolymer of the present disclosure comprises a first structural unit represented by Formula (1) and a second structural unit represented by Formula (2). In Formula (1), R1 is a hydrogen atom or a methyl group. R2 and R3 are each independently a hydrogen atom or an alkyl group having from 1 to 4 carbons. x1 is an integer of 1 to 4. In Formula (2), R4 is a hydrogen atom or a methyl group. R5 and R6 are each independently a hydrogen atom or an alkyl group having from 1 to 4 carbons. x2 is an integer of 1 to 4, and y is an integer of 3 to 7.

Abstract: Solution A copolymer according to the present disclosure is a copolymer of a compound represented by Formula (1) and a compound represented by Formula (2). R1 and R4 are each independently a hydrogen atom or a methyl group. R2 and R3 are each independently a hydrogen atom or an alkyl group having from 1 to 4 carbon atom(s). R5 and R6 are each independently an alkyl group having from 1 to 4 carbon atom(s). x, y, and z are each independently an integer from 1 to 4.

Abstract: A measurement method includes a measurement step of measuring a first single value and a second signal value, the first signal value being based on a reaction between a first reacting substance and the sample, the second signal value being based on a reaction between a second reacting substance and the sample, the first reacting substance having a higher reactivity to a second detection target than to a first detection target, the second reacting substance having a higher reactivity to the first detection target than to the second detection target.

Abstract: There is provided a sensor and the like which can detect a first substance with high accuracy. A sensor for detecting whether an analyte contains a first substance, includes a base and a detection section including a second substance immobilized on a surface of the base. The second substance includes an amino acid, a bond which can be cleaved by a reaction with an enzyme, and a first compound which is bonded to the amino acid by the bond and includes a first group capable of bonding to other substances, and the analyte is configured to be introduced to the detection section by being contacted with a third substance which generates the enzyme by a reaction with the first substance.

Abstract: In an aspect, a sensor includes a combining portion 240 that combines with a second substance 220 having a molecular weight larger than a molecular weight of a first substance 210. Further, in an aspect, the sensor includes a substrate 10 including a surface on which the combining portion 240 is disposed, the combining portion 240 detecting whether or not the first substance 210 is included in an analyte that has come into contact with both an aptamer 230 including a first combining part 231 for the first substance 210 and a second combining part 232 for the second substance 220 and being combined with either of the first substance 210 and the second substance 220 and the second substance 220.

Abstract: In an aspect, a sensor includes a combining portion 240 that combines with a second substance 220 having a molecular weight larger than a molecular weight of a first substance 210. Further, in an aspect, the sensor includes a substrate 10 including a surface on which the combining portion 240 is disposed, the combining portion 240 detecting whether or not the first substance 210 is included in an analyte that has come into contact with both an aptamer 230 including a first combining part 231 for the first substance 210 and a second combining part 232 for the second substance 220 and being combined with either of the first substance 210 and the second substance 220 and the second substance 220.

Abstract: A measurement method according to one embodiment, includes: preparing a detecting section on an upper surface of a measurement device with a reaction substance that can react specifically with a detection substance and a correction substance, wherein the detecting section measures signal values based on reactions of the reaction substance; supplying the detection substance onto the detecting section; supplying the correction substance onto the detecting section; measuring a first signal value of the signal values based on a specific reaction between the detection substance and the reaction substance; measuring a second signal value of the signal values based on a specific reaction between the correction substance and the reaction substance; and correcting the first signal value using the second signal value.

Abstract: A sensor determines whether a specimen includes a first substance. In an exemplary embodiment, the sensor includes a base. In an exemplary embodiment, the sensor is configured to determine whether the specimen includes the first substance and further includes, on the base, a detection unit on which a second substance is immobilized. The second substance includes a bond that is cleft by the reaction with hydrogen peroxide. In an exemplary embodiment, the specimen that is brought in contact with an enzyme that generates the hydrogen peroxide by the reaction with the first substance is introduced to the detection unit in the sensor configured to determine whether the specimen includes the first substance.

Abstract: The present invention provides a surface acoustic wave sensor capable of suitably controlling the flow of a liquid sample onto IDT electrodes. A surface acoustic wave sensor has a piezoelectric substrate, a first IDT electrode and a second IDT electrode which are located on the upper surface of the piezoelectric substrate and are separated from each other while sandwiching a detection part on the piezoelectric substrate therebetween, and the cover which forms the space being on the first IDT electrode, second IDT electrode, and the detection part and straddling them. On the lower surface of the cover, the detection part-facing surface facing the detection part has a smaller contact angle to the liquid sample than that of a pair of electrode-facing surfaces facing the first IDT electrode and second IDT electrode.

Abstract: A biosensor, including: a first cover member comprising an element-accommodating recess in an upper face thereof; a detection element using a surface acoustic wave, the detection element including an element substrate accommodated in the element-accommodating recess, and at least one detection unit located on an upper face of the element substrate configured to perform detection of an analyte; and a second cover member joined to the first cover member and covering the detection element, and including an inflow port from which the analyte flows in and a groove which extends from the inflow port to at least above the at least one detection unit and constitutes a capillary.

Abstract: A sensor is provided with a sensor element which outputs a signal in accordance with a detected object contained in a specimen positioned on a detection part in an element surface and with a package which accommodates the sensor element inside it and has a passage including a space positioned on the element surface. A lower surface of the passage has the element surface and a lower surface of an inflow passage extending toward the space, and a gap is positioned between the lower surface of the inflow passage and the element surface. The element surface is positioned above the lower surface of the inflow passage.

Abstract: The present invention provides a surface acoustic wave sensor capable of suitably controlling the flow of a liquid sample onto IDT electrodes. A surface acoustic wave sensor has a piezoelectric substrate, a first IDT electrode and a second IDT electrode which are located on the upper surface of the piezoelectric substrate and are separated from each other while sandwiching a detection part on the piezoelectric substrate therebetween, and the cover which forms the space being on the first IDT electrode, second IDT electrode, and the detection part and straddling them. On the lower surface of the cover, the detection part-facing surface facing the detection part has a smaller contact angle to the liquid sample than that of a pair of electrode-facing surfaces facing the first IDT electrode and second IDT electrode.

Abstract: In an aspect, a sensor includes a combining portion 240 that combines with a second substance 220 having a molecular weight larger than a molecular weight of a first substance 210. Further, in an aspect, the sensor includes a substrate 10 including a surface on which the combining portion 240 is disposed, the combining portion 240 detecting whether or not the first substance 210 is included in an analyte that has come into contact with both an aptamer 230 including a first combining part 231 for the first substance 210 and a second combining part 232 for the second substance 220 and being combined with either of the first substance 210 and the second substance 220 and the second substance 220.

Abstract: A measurement method includes a measurement step of measuring a first single value and a second signal value, the first signal value being based on a reaction between a first reacting substance and the sample, the second signal value being based on a reaction between a second reacting substance and the sample, the first reacting substance having a higher reactivity to a second detection target than to a first detection target, the second reacting substance having a higher reactivity to the first detection target than to the second detection target.

Abstract: The present invention provides a surface acoustic wave sensor capable of suitably controlling the flow of a liquid sample onto IDT electrodes. A surface acoustic wave sensor 1 has a piezoelectric substrate, a first IDT electrode and a second IDT electrode which are located on the upper surface of the piezoelectric substrate and are separated from each other while sandwiching a detection part (detection region) on the piezoelectric substrate there between, and the cover which forms the space being on the first IDT electrode, second IDT electrode, and detection part and straddling them. On the lower surface of the cover, the detection part-facing surface (lower surface of the film) facing the detection part has a smaller contact angle to the liquid sample than that of a pair of electrode-facing surfaces (lower surface of the cover body) facing the first IDT electrode and second IDT electrode.

Abstract: In an aspect, a sensor includes a combining portion that combines with a second substance having a molecular weight larger than a molecular weight of a first substance. Further, in an aspect, the sensor includes a substrate including a surface on which the combining portion is disposed. The combining portion detects whether or not the first substance is included in an analyte that has come into contact with both an aptamer and the second substance. The aptamer includes a first combining part for the first substance and a second combining part for the second substance and is combined with either of the first substance and the second substance.

Abstract: A biosensor, including: a first cover member comprising an element-accommodating recess in an upper face thereof; a detection element using a surface acoustic wave, the detection element including an element substrate accommodated in the element-accommodating recess, and at least one detection unit located on an upper face of the element substrate configured to perform detection of an analyte; and a second cover member joined to the first cover member and covering the detection element, and including an inflow port from which the analyte flows in and a groove which extends from the inflow port to at least above the at least one detection unit and constitutes a capillary.

Abstract: There is provided a sensing method which can detect a detection target with good sensitivity. A detection target sensing method includes supplying a detection target to a base having a first substance immobilized on a surface thereof, the detection target being bindable to the first substance; supplying a second substance to the base after the detection target is supplied thereto, the second substance being bindable to the detection target; and supplying a metal particle to the base after the second substance is supplied thereto, the metal particle being bindable to the second substance.

Abstract: To provide a biosensor including a suctioning mechanism while using a detection element such as a surface acoustic wave device, included are: a first cover member 1 including an element-accommodating recess 5 on an upper face thereof; a detection element 3 including an element substrate 10, and at least one detection unit 13 located on the upper face of the element substrate 10 to perform detection of an analyte; and a second cover member 2 joined to the first cover member 1 and covering the detection element 3, and including an inflow port 14 from which the analyte flows in and a groove 15 extending from the inflow port 14 to at least above the detection unit.

Abstract: An RNA aptamer is provided with a sequence of linkage order of UAUUAGGACCA.