Abstract: A method of electric wire routing includes: routing an electric wire in an electric wire routing path which is provided in a case and has a concave shape in a cross-sectional view; and covering an upper portion of the electric wire routing path with a cover. A pair of guide pins are inserted into a through hole formed in a bottom portion of the electric wire routing path in the case from below to a position above a side wall portion which forms the electric wire routing path. The electric wire is passed between the guide pins. The cover is assembled to the upper portion of the electric wire routing path while the guide pins are pulled out from the through hole.

Abstract: A connection structure for an electric wire includes an electric wire that has a conductor and an outer sheath covering the conductor; a bonding member that is made of a conductive metal material and is attached to the electric wire and; and a busbar that is made of a conductive metal material and on which the bonding member is overlapped and ultrasonically bonded with the conductor interposed between the busbar and the bonding member. The bonding member includes a crimping portion for crimping and fixing the electric wire.

Abstract: A connection structure for an electric wire includes an electric wire that has a conductor and an outer sheath covering the conductor; a bonding member that is made of a conductive metal material and is attached to the electric wire and; and a busbar that is made of a conductive metal material and on which the bonding member is overlapped and ultrasonically bonded with the conductor interposed between the busbar and the bonding member. The bonding member includes a crimping portion for crimping and fixing the electric wire.

Abstract: A method of electric wire routing includes: routing an electric wire in an electric wire routing path which is provided in a case and has a concave shape in a cross-sectional view; and covering an upper portion of the electric wire routing path with a cover. A pair of guide pins are inserted into a through hole formed in a bottom portion of the electric wire routing path in the case from below to a position above a side wall portion which forms the electric wire routing path. The electric wire is passed between the guide pins. The cover is assembled to the upper portion of the electric wire routing path while the guide pins are pulled out from the through hole .

Abstract: The present invention relates to a method for assaying soluble GPC3 protein in a test sample, comprising using two different antibodies binding to different epitopes present in the N-terminal region of GPC3 protein.

Abstract: A rotating connector includes a movable housing and a steering angle sensor unit. The movable housing includes a cylindrical section through which a steering shaft penetrates and a main gear integrally molded with the movable housing on an outer circumferential surface of the cylindrical section along a rotation direction. The steering angle sensor unit includes a fixed-side housing into which the cylindrical section of the movable housing is inserted, a satellite gear which is provided in the fixed-side housing and meshed with the main gear, and a rotation angle detection unit which is provided in the fixed-side housing and detects rotation of the satellite gear.

Abstract: A case with connector includes a connector; a case body that has a cylindrical side wall portion and an end wall portion closing one end side of the side wall portion and forming an accommodation portion along with the side wall portion, the case body being formed by insert molding and integrated with the connector at the side wall portion; and an electrical wire that has an end connected to the connector and the other end projecting to the accommodation portion.

Abstract: A case with connector includes a connector; a case body that has a cylindrical side wall portion and an end wall portion closing one end side of the side wall portion and forming an accommodation portion along with the side wall portion, the case body being formed by insert molding and integrated with the connector at the side wall portion; and an electrical wire that has an end connected to the connector and the other end projecting to the accommodation portion.

Abstract: The present inventors obtained, from a phage library of human antibodies, an anti-mouse NR 10 neutralizing antibody-expressing BM095 clone that shows a strong proliferation-suppressing activity in an IL-31-dependent Ba/F3 cell proliferation assay system. When this anti-mouse NR 10 neutralizing antibody was administered to NC/Nga mice, a model of atopic dermatitis which is a mouse model of chronic dermatitis that arises as a result of repeated applications of picryl chloride, a mouse model of rheumatoid arthritis, and a mouse model of osteoarthritis, a significant effect of symptom suppression was observed. This revealed that the anti-NR 10 neutralizing antibody is indeed effective as a therapeutic agent for inflammatory diseases. In addition, the present inventors successfully obtained an anti-human NR 10 neutralizing antibody, providing extremely useful therapeutic agents with practical clinical applications.

Abstract: The present invention relates to a method for assaying soluble GPC3 protein in a test sample, comprising using two different antibodies binding to different epitopes present in the N-terminal region of GPC3 protein.

Abstract: A rotating connector includes a movable housing and a steering angle sensor unit. The movable housing includes a cylindrical section through which a steering shaft penetrates and a main gear integrally molded with the movable housing on an outer circumferential surface of the cylindrical section along a rotation direction. The steering angle sensor unit includes a fixed-side housing into which the cylindrical section of the movable housing is inserted, a satellite gear which is provided in the fixed-side housing and meshed with the main gear, and a rotation angle detection unit which is provided in the fixed-side housing and detects rotation of the satellite gear.

Abstract: The present inventors obtained, from a phage library of human antibodies, an anti-mouse NR 10 neutralizing antibody-expressing BM095 clone that shows a strong proliferation-suppressing activity in an IL-31-dependent Ba/F3 cell proliferation assay system. When this anti-mouse NR 10 neutralizing antibody was administered to NC/Nga mice, a model of atopic dermatitis which is a mouse model of chronic dermatitis that arises as a result of repeated applications of picryl chloride, a mouse model of rheumatoid arthritis, and a mouse model of osteoarthritis, a significant effect of symptom suppression was observed. This revealed that the anti-NR 10 neutralizing antibody is indeed effective as a therapeutic agent for inflammatory diseases. In addition, the present inventors successfully obtained an anti-human NR 10 neutralizing antibody, providing extremely useful therapeutic agents with practical clinical applications.

Abstract: A rotating connector includes a cable accommodation chamber formed between an outer case and an inner case in their radial direction, a flexible flat cable housed in the cable accommodation chamber, and multiple idlers housed in the cable accommodation chamber. The idlers are rotatably provided in a direction of an annular slidable member. The idlers are rotatable on their own axes. The flat cable is wound on an inner periphery of the outer case and an outer periphery of the inner case by way of a reversed portion of the flat cable. The flat cable is wound thereon in opposite directions. The idlers are pivotally supported by the slidable member so as to change a space between the idlers and the inner case and a space between the idlers and the outer case depending on winding of the flat cable.

Abstract: The present inventors obtained, from a phage library of human antibodies, an anti-mouse NR 10 neutralizing antibody-expressing BM095 clone that shows a strong proliferation-suppressing activity in an IL-31-dependent Ba/F3 cell proliferation assay system. When this anti-mouse NR 10 neutralizing antibody was administered to NC/Nga mice, a model of atopic dermatitis which is a mouse model of chronic dermatitis that arises as a result of repeated applications of picryl chloride, a mouse model of rheumatoid arthritis, and a mouse model of osteoarthritis, a significant effect of symptom suppression was observed. This revealed that the anti-NR 10 neutralizing antibody is indeed effective as a therapeutic agent for inflammatory diseases. In addition, the present inventors successfully obtained an anti-human NR 10 neutralizing antibody, providing extremely useful therapeutic agents with practical clinical applications.

Abstract: A rotating connector includes a cable accommodation chamber formed between an outer case and an inner case in their radial direction, a flexible flat cable housed in the cable accommodation chamber, and multiple idlers housed in the cable accommodation chamber. The idlers are rotatably provided in a direction of an annular slidable member. The idlers are rotatable on their own axes. The flat cable is wound on an inner periphery of the outer case and an outer periphery of the inner case by way of a reversed portion of the flat cable. The flat cable is wound thereon in opposite directions. The idlers are pivotally supported by the slidable member so as to change a space between the idlers and the inner case and a space between the idlers and the outer case depending on winding of the flat cable.

Abstract: A rotary connector, comprises an annular rotary body inserted outside a steering shaft and integrally rotated with a steering wheel, a rotator of a steering angle sensor inserted outside the steering shaft; and a tubular joint inserted outside the steering shaft and connecting the rotary body to the rotator; wherein the rotary body and the joint are connected together by a first universal joint, and the joint and the rotator are connected together by a second universal joint.

Abstract: A non-human animal that produces human tissue factor (TF) without substantially producing non-human animal tissue factor, said animal having a genome in which cDNA encoding human TF has been inserted upstream of the translation initiation codon for the non-human animal genomic TF gene.

Abstract: A layout apparatus lays out a document by referencing personal information registered on a per user basis. Even if no particular print setting is input for a print job by a user, excellent prints customized for each user are thus provided.

Abstract: A non-human animal that produces human tissue factor (TF) without substantially producing non-human animal tissue factor, said animal having a genome in which cDNA encoding human TF has been inserted upstream of the translation initiation codon for the non-human animal genomic TF gene.

Abstract: A rotary connector, comprises an annular rotary body inserted outside a steering shaft and integrally rotated with a steering wheel, a rotator of a steering angle sensor inserted outside the steering shaft; and a tubular joint inserted outside the steering shaft and connecting the rotary body to the rotator; wherein the rotary body and the joint are connected together by a first universal joint, and the joint and the rotator are connected together by a second universal joint.