Patents by Inventor Hideki Hasegawa

Hideki Hasegawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8941060
    Abstract: The quantitative accuracy of analysis is improved without reducing the dynamic range for measurement of concentrations by performing stable ionization through electrospray or the like which repeats sampling and ionization using a movable probe electrode. A voltage is applied from a high-voltage power source 4 to a sample transport electrode 7 having a plurality of probe electrodes 1 and a driving section 3 drives the sample transport electrode 7 to rotate. The plurality of probe electrodes 1, to which a sample solution 5 is adhered, are sequentially transported to an inlet 21 of a mass spectrometer 20, thus electrospray ionization is continuously performed.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: January 27, 2015
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Hiroyuki Satake, Hideki Hasegawa, Masuyuki Sugiyama, Yuichiro Hashimoto
  • Publication number: 20150001392
    Abstract: An object of the present invention is to prevent lowering of introduction efficiency of ions and to reduce labor for a cleaning operation. In order to solve the above problems, the present invention provides a mass spectrometer where ion introduction hole of an electrode is divided into a first region, a second region, and a third region, a central axis direction of the ion introduction hole in both or either one of the first region and the third region is different from a flow direction axis of the ion inside the ion introduction hole in the second region, and axes of the ion introduction hole in the first region and the third region are in an eccentric position relationship.
    Type: Application
    Filed: December 21, 2012
    Publication date: January 1, 2015
    Inventors: Hideki Hasegawa, Hiroyuki Satake, Masao Suga, Yuichiro Hashimoto
  • Patent number: 8866070
    Abstract: A mass spectrometer of reduced size and weight is provided which is capable to conduct highly accurate mass spectroscopy. The mass spectrometer includes an ion source adapted to ionize gas flowing in from outside in order to ionize a measurement sample and a mass spectroscopy section for separating the ionized measurement sample. The ion source has its interior reduced in pressure by differential pumping from the mass spectroscopy section and ionizes the gas when the interior pressure rises as it inhales the gas, and the mass spectroscopy section separates the ionized measurement sample when its interior pressure falls after inhale of the gas. The mass spectrometer may further include a restriction device for suppressing a flow rate of the gas the ion source inhales and an open/close device for opening and closing a flow of the gas the ion source inhales.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: October 21, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Hidetoshi Morokuma, Yuichiro Hashimoto, Masuyuki Sugiyama, Masuyoshi Yamada, Hideki Hasegawa
  • Patent number: 8835841
    Abstract: A mass spectrometer possessing both high resolution and durability in a simple, compact structure compared to mass spectrometers of the related art, and characterized in possessing a linear ion trap unit containing a multipolar rod electrode including rod electrodes having fine orifices to allow passage of electrons or ions; a mechanism to move the ions inside the linear ion trap unit along the axis of the multipolar rod electrode; and a detector to selectively detect by mass, ions ejected from the linear ion trap unit.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: September 16, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Yuichiro Hashimoto, Hideki Hasegawa, Masuyuki Sugiyama, Hiroyuki Satake
  • Patent number: 8835834
    Abstract: An object is to measure both cations and anions with high duty cycle. In a mass spectrometer comprising an ion source (1), an ion guide part (31), and an ion trap (32), while ions are being mass-selectively ejected from the ion trap, ions having a polarity reverse to that of the ions trapped in the ion trap are introduced into the ion guide part.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: September 16, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Masuyuki Sugiyama, Yuichiro Hashimoto, Hisashi Nagano, Hideki Hasegawa, Yasuaki Takada, Masuyoshi Yamada
  • Patent number: 8680464
    Abstract: A mass spectrometer having a resolution improved by introducing ions into a mass spectrometry part with a high efficiency is provided with a small-sized, simple configuration. The mass spectrometer includes an opening/closing mechanism provided between a sample introducing piping part for introducing a sample into the mass spectrometry part and the mass spectrometry part to conduct gas introduction intermittently and control sample passage. The mass spectrometer further includes a pump mechanism to evacuate a high pressure side of the sample introducing piping part, that is, an opposite side of the opening/closing mechanism to the mass spectrometry part to have a pressure in a range of 100 to 10,000 Pa.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: March 25, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Yuichiro Hashimoto, Hideki Hasegawa, Masuyuki Sugiyama, Hidetoshi Morokuma
  • Publication number: 20130334416
    Abstract: The quantitative accuracy of analysis is improved without reducing the dynamic range for measurement of concentrations by performing stable ionization through electrospray or the like which repeats sampling and ionization using a movable probe electrode. A voltage is applied from a high-voltage power source 4 to a sample transport electrode 7 having a plurality of probe electrodes 1 and a driving section 3 drives the sample transport electrode 7 to rotate. The plurality of probe electrodes 1, to which a sample solution 5 is adhered, are sequentially transported to an inlet 21 of a mass spectrometer 20, thus electrospray ionization is continuously performed.
    Type: Application
    Filed: January 27, 2012
    Publication date: December 19, 2013
    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Hiroyuki Satake, Hideki Hasegawa, Masuyuki Sugiyama, Yuichiro Hashimoto
  • Publication number: 20130240726
    Abstract: This mass spectrometer is provided with an ion guide (37) having a multipole rod electrode (1), a power source unit (5) for applying voltage to the multipole rod electrode, and a control unit for controlling the power source unit, said mass spectrometer being characterised by the multipole rod electrode having a rod electrode divided into a plurality of segmented rods (2A-1, 2A-2, 2B-1, 2B-2, 2C-1, 2C-2, 2D-1, 2D-2) at mutually different positions in the axial direction. Thus enabled is low-cost, high-throughput analysis.
    Type: Application
    Filed: October 3, 2011
    Publication date: September 19, 2013
    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Hideki Hasegawa, Masuyuki Sugiyama, Hiroyuki Satake, Yuichiro Hashimoto
  • Patent number: 8525108
    Abstract: The mass spectrometer is characterized in that a linear ion trap, that consists of electrodes for mass-selective discharge, is provided with a mechanism that excites ions in a first direction that is perpendicular to the rod axes and a mechanism that simultaneously generates an electric field on the axes in a second direction that is perpendicular to the axial direction and the first direction in order to generate an electric field on the central axis. Highly efficient, high-speed scanning can be achieved using this configuration.
    Type: Grant
    Filed: August 25, 2009
    Date of Patent: September 3, 2013
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Yuichiro Hashimoto, Hideki Hasegawa, Masuyuki Sugiyama
  • Publication number: 20130056633
    Abstract: A mass spectrometer having a resolution improved by introducing ions into a mass spectrometry part with a high efficiency is provided with a small-sized, simple configuration. The mass spectrometer includes an opening/closing mechanism provided between a sample introducing piping part for introducing a sample into the mass spectrometry part and the mass spectrometry part to conduct gas introduction intermittently and control sample passage. The mass spectrometer further includes a pump mechanism to evacuate a high pressure side of the sample introducing piping part, that is, an opposite side of the opening/closing mechanism to the mass spectrometry part to have a pressure in a range of 100 to 10,000 Pa.
    Type: Application
    Filed: November 2, 2012
    Publication date: March 7, 2013
    Inventors: Yuichiro HASHIMOTO, Hideki HASEGAWA, Masuyuki SUGIYAMA, Hidetoshi MOROKUMA
  • Publication number: 20130048851
    Abstract: A mass spectrometer for efficiently ionizing a sample with less carry-over. The ratio of the amount of sample gas to that of a whole headspace gas is increased by decreasing the pressure inside of a sample vessel in which the sample is sealed thereby efficiently ionizing the sample.
    Type: Application
    Filed: July 31, 2012
    Publication date: February 28, 2013
    Inventors: Shun KUMANO, Masuyuki SUGIYAMA, Yuichiro HASHIMOTO, Hideki HASEGAWA, Masuyoshi YAMADA, Kazushige NISHIMURA, Hidetoshi MOROKUMA
  • Patent number: 8368013
    Abstract: An analyzer performs dielectric barrier discharge and ionization of a sample by a reaction between the sample and excited molecules or ions generated by the dielectric barrier discharge at a pressure lower than an atmospheric pressure.
    Type: Grant
    Filed: April 12, 2011
    Date of Patent: February 5, 2013
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Masako Ishimaru, Yuichiro Hashimoto, Hideki Hasegawa, Masuyoshi Yamada, Masuyuki Sugiyama, Hidetoshi Morokuma
  • Publication number: 20120326022
    Abstract: A mass spectrometer including a sample attaching member of attaching a sample, an ionizing chamber including an introductory port of the sample attaching member and an ionization source of generating a sample ion, a vacuumed chamber having a mass analyzer of analyzing the sample ion, and an opening/closing mechanism provided between the ionizing chamber and the vacuumed chamber, in which the opening/closing mechanism is controlled from a closed state to an open state after introducing the sample attaching member into the ionizing chamber to thereby enable to perform ionization with inconsiderable fragmentation at a high sensitivity with a high throughput
    Type: Application
    Filed: June 20, 2012
    Publication date: December 27, 2012
    Inventors: Shun KUMANO, Masuyuki Sugiyama, Yuichiro Hashimoto, Hideki Hasegawa, Masuyoshi Yamada, Hidetoshi Morokuma, Shuhei Hashiba
  • Publication number: 20120292495
    Abstract: A mass spectrometer possessing both high resolution and durability in a simple, compact structure compared to mass spectrometers of the related art, and characterized in possessing a linear ion trap unit containing a multipolar rod electrode including rod electrodes having fine orifices to allow passage of electrons or ions; a mechanism to move the ions inside the linear ion trap unit along the axis of the multipolar rod electrode; and a detector to selectively detect by mass, ions ejected from the linear ion trap unit.
    Type: Application
    Filed: December 22, 2010
    Publication date: November 22, 2012
    Inventors: Yuichiro Hashimoto, Hideki Hasegawa, Masuyuki Sugiyama, Hiroyuki Satake
  • Publication number: 20120292501
    Abstract: A mass spectrometer of ionizing a sample by a dielectric barrier discharge under a reduced pressure. An ionization with inconsiderable fragmentation can be carried out highly sensitively by the present invention.
    Type: Application
    Filed: January 21, 2011
    Publication date: November 22, 2012
    Inventors: Masuyuki Sugiyama, Yuichiro Hashimoto, Hideki Hasegawa
  • Patent number: 8293330
    Abstract: While one side of a lens L is held by a suction-holding member 17 and the suction-holding member 17 is moved by the moving mechanism, a coating process, a drying process, and a curing process are sequentially performed in respective receptacles disposed independently of each other. A suction force applied to the lens L by the suction-holding member 17 is controlled by a control section 22 in accordance with each of the receptacles in which the suction-holding member 17 is positioned.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: October 23, 2012
    Assignee: Hoya Corporation
    Inventors: Kenichi Shinde, Katsuaki Uchida, Tomohiro Ogawa, Tetsuhisa Nakamura, Hideki Hasegawa
  • Publication number: 20120223223
    Abstract: A variation in an ionization efficiency and the amount of sample which is introduced into an ion trap is corrected and quantified. Ions of an internal standard and ions of a sample are trapped in the ion trap at the same time, and a concentration of the sample is quantified according to an intensity of the ions of the internal standard which are mass-selectively ejected, and an intensity of fragment ions of the sample.
    Type: Application
    Filed: February 3, 2012
    Publication date: September 6, 2012
    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Masuyuki SUGIYAMA, Yuichiro HASHIMOTO, Hideki HASEGAWA, Shuhei HASHIBA, Shun KUMANO
  • Publication number: 20120112059
    Abstract: An object is to measure both cations and anions with high duty cycle. In a mass spectrometer comprising an ion source (1), an ion guide part (31), and an ion trap (32), while ions are being mass-selectively ejected from the ion trap, ions having a polarity reverse to that of the ions trapped in the ion trap are introduced into the ion guide part.
    Type: Application
    Filed: July 9, 2010
    Publication date: May 10, 2012
    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Masuyuki Sugiyama, Yuichiro Hashimoto, Hisashi Nagano, Hideki Hasegawa, Yasuaki Takada, Masuyoshi Yamada
  • Publication number: 20120112061
    Abstract: A mass spectrometer of reduced size and weight is provided which is capable to conduct highly accurate mass spectroscopy. The mass spectrometer includes an ion source adapted to ionize gas flowing in from outside in order to ionize a measurement sample and a mass spectroscopy section for separating the ionized measurement sample. The ion source has its interior reduced in pressure by differential pumping from the mass spectroscopy section and ionizes the gas when the interior pressure rises as it inhales the gas, and the mass spectroscopy section separates the ionized measurement sample when its interior pressure falls after inhale of the gas. The mass spectrometer may further include a restriction device for suppressing a flow rate of the gas the ion source inhales and an open/close device for opening and closing a flow of the gas the ion source inhales.
    Type: Application
    Filed: November 4, 2011
    Publication date: May 10, 2012
    Inventors: Hidetoshi MOROKUMA, Yuichiro HASHIMOTO, Masuyuki SUGIYAMA, Masuyoshi YAMADA, Hideki HASEGAWA
  • Patent number: 8164053
    Abstract: There has been a problem that both detection sensitivity and throughput cannot be improved simultaneously by a conventional MS/MS analysis method. A mass analyzer having an ion trap for ejecting ions in a specific mass range, a collisional dissociation part for causing ions ejected from the ion trap to be dissociated, a mass analyzing part for performing a mass analysis of ions ejected from the collisional dissociation part, and a control part including a list in which measurement conditions for each ion are stored selectively resonance-ejects ions introduced into and accumulated in the ion trap based on masses.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: April 24, 2012
    Assignee: Hitachi, Ltd.
    Inventors: Masuyuki Sugiyama, Yuichiro Hashimoto, Hideki Hasegawa, Yasuaki Takada