Abstract: A screw driver capable of avoiding co-rotation of an end bit and a motor in case of sharp shooting the end bit with a groove in a head of a screw. A co-rotation preventing mechanism is engageable with an end bit mounting portion when the end bit mounting portion is at a frontward position to prevent the end bit mounting portion from being rotated in the forward direction and to allow the end bit mounting portion to rotate in the reverse direction. The preventing mechanism is disengageable from the end bit mounting portion when the end bit mounting portion is at the rearward position to allow the end bit mounting portion to rotate in both forward and reverse directions.

Abstract: Problems: To provide a polyvinylidene fluoride microporous membrane which has high water permeability and separation performance and is excellent in mechanical and chemical strength; and a process for producing the film. Means for Solving Problems: An anisotropic polyvinylidene fluoride hollow fiber microporous membrane characterized in that the porosity of the cross-sectional bulk layer is higher than the membrane surface porosity of the outer layer and that in the cross section of the membrane, the dense microstructure of the outer surface changes substantially discontinuously into the coarse structure of the bulk layer.

Abstract: The present invention relates to an N-substituted benzothiophenesulfonamide derivative or a pharmaceutically acceptable salt thereof and applications thereof. Furthermore, it provides an agent for preventing or treating cardiac or circulatory disease and so on caused by abnormal increase of production of angiotensin II or endothelin I based on chymase activity, or by activation of mast cell, and an agent for preventing adhesion after surgery, wherein the agent has a selective inhibitory action on chymase.

Abstract: A method of fabricating a device including plural electronic parts mounted on a circuit board with mounting areas for mounting the electronic parts being covered by a sealing resin is disclosed. The method prevents small air bubbles from entering into the sealing resin near the electronic parts. The method includes the steps of, before applying the sealing resin, applying an under-fill resin near the electronic parts with plural nozzles at the same time, and hardening the under-fill resin to form a taper-shaped structure around the electronic parts.

Abstract: A knuckle bracket (1) for a cylinder (20) comprises outer and inner brackets (2, 10). The outer bracket (2) comprises a pair of outer plates (4, 5) projecting in a lateral direction with respect to a cylinder axis. The inner bracket (10) comprises a pair of inner plates (12, 13) overlap the outer plates (4, 5) on the inner side thereof. A guide (17) of having outwardly curved shape is formed on a leading edge (X, Y) of each of the inner plates (12, 13) so as to facilitate introduction of a connecting part (90) of a knuckle bracket (N) into the inner bracket (10). By forming a notch (7) on a leading edge of each of the outer plates (4, 5) to accommodate the guide (17), the size of the knuckle bracket (1) can be suppressed.

Abstract: Temperature sensors are produced by first producing temperature sensing elements each having electrodes on its mutually oppositely facing main surfaces, next forming a lead frame comprising a linearly elongated base part and a plurality of pairs of planar lead parts extending perpendicularly from said base part, twisting each of these planar lead parts such that each of the pairs has top end parts which face each other with a gap therebetween, inserting one of the temperature sensing elements between the mutually facing top end parts of each pair in the corresponding gap and electrically connecting the electrodes on the inserted temperature sensing element individually to the top end parts of the corresponding pair, and cutting each of the planar lead parts from said base part to form lead terminals of specified lengths for the temperature sensors.

Abstract: Temperature sensors are produced by first producing temperature sensing elements each having electrodes on its mutually oppositely facing main surfaces, next forming a lead frame comprising a linearly elongated base part and a plurality of pairs of planar lead parts extending perpendicularly from said base part, twisting each of these planar lead parts such that each of the pairs has top end parts which face each other with a gap therebetween, inserting one of the temperature sensing elements between the mutually facing top end parts of each pair in the corresponding gap and electrically connecting the electrodes on the inserted temperature sensing element individually to the top end parts of the corresponding pair, and cutting each of the planar lead parts from said base part to form lead terminals of specified lengths for the temperature sensors.

Abstract: A temperature sensor has lead lines made of an elastic material each attached to a corresponding one of electrodes on a temperature sensing element such as an NTC thermistor element. The lead lines may each have a non-straight part where they are bent or deformed into a semi-circular shape such that, when these lead lines are inserted into throughholes prepared through a circuit board, the non-straight parts are hooked at the throughholes and the portions of the lead lines above the circuit board will stand up obliquely. Instead of lead lines, a pair of elongated planar lead terminals each with a twisted top end part may be connected to the electrodes such that the top end parts of the pair of lead terminals face each other and can support the temperature sensing element more securely in between.

Abstract: The present invention relates to an N-substituted benzothiophenesulfonamide derivative or a pharmaceutically acceptable salt thereof and applications thereof. Furthermore, it provides an agent for preventing or treating cardiac or circulatory disease and so on caused by abnormal increase of production of angiotensin II or endothelin I based on chymase activity, or by activation of mast cell, and an agent for preventing adhesion after surgery, wherein the agent has a selective inhibitory action on chymase.

Abstract: The present invention relates to an N-substituted benzothiophenesulfonamide derivative or a pharmaceutically acceptable salt thereof and applications thereof. Furthermore, it provides an agent for preventing or treating cardiac or circulatory disease and so on caused by abnormal increase of production of angiotensin II or endothelin I based on chymase activity, or by activation of mast cell, and an agent for preventing adhesion after surgery, wherein the agent has a selective inhibitory action on chymase.

Abstract: The present invention relates to a compound of the formula [1?] wherein R2 is lower alkyl optionally substituted by hydroxy, amino and the like, ring B is phenyl, thienyl and the like, E is a single bond, —O—, —S— and the like, ring G is aryl, heterocyclic group and the like, R5 is halogen atom, hydroxy, lower alkyl optionally substituted by halogen atom etc., and the like, t is 0 or an integer of 1 to 5, when t is an integer of 2 to 5, each R5 may be the same or different, m is 0 or an integer of 1 to 8, and n is 0 or an integer of 1 to 4, and a nociceptin antagonist containing compound [1?] as an active ingredient. The compound [1?] shows, due to nociceptin antagonistic action, analgesic effect against sharp pain such as postoperative pain and the like. The present invention also relates to the use of certain amide derivative inclusive of compound [1?] as a nociceptin antagonist or analgesic.

Abstract: A halogenobenzylaminopropionic acid derivative represented by the following formula (1): or a pharmaceutically acceptable salt of the derivative, and a drug containing the same as an active ingredient for treating diabetes, hyperlipidemia, or similar pathological conditions.

Abstract: The present invention relates to a compound of the formula [1?] ? wherein R2 is lower alkyl optionally substituted by hydroxy, amino and the like, ring B is phenyl, thienyl and the like, E is a single bond, —O—, —S— and the like, ring G is aryl, heterocyclic group and the like, R5 is halogen atom, hydroxy, lower alkyl optionally substituted by halogen atom etc., and the like, t is 0 or an integer of 1 to 5, when t is an integer of 2 to 5, each R5 may be the same or different, m is 0 or an integer of 1 to 8, and n is 0 or an integer of 1 to 4, and a nociceptin antagonist containing compound [1?] as an active ingredient. The compound [1?] shows, due to nociceptin antagonistic action, analgesic effect against sharp pain such as postoperative pain and the like. The present invention also relates to the use of certain amide derivative inclusive of compound [1?] as a nociceptin antagonist or analgesic.

Abstract: Systems and methods to provide an availability and price determination, in response to a request for function space, to a user in real-time. For one embodiment, a request for a function space is received at a digital processing system that contains availability information and a set of pricing rules for one or more function spaces. The request includes a plurality of criteria. An availability of the requested function space is determined based upon the availability information and one or more of the criterion. A price for the requested function space is determined based upon the set of pricing rules and one or more of the criterion.

Abstract: The present invention relates to a composite semipermeable membrane, which is useful as a reverse osmosis membrane or a nano-filtration membrane and comprises a polysulfone porous support membrane and a polyamide ultrathin layer formed on one of the surfaces of the porous support membrane, the composite membrane having the characteristic that in the infrared absorption spectrum obtained from the surface of a polyamide ultrathin layer of the composite semipermeable membrane, the ratio T (=Aa/As) of absorption intensity Aa at the absorption peak revealing C═O of polyamide in the region of 1600-1700 cm−1 to absorption intensity As at the absorption peak revealing polysulfone at a wavenumber around 1586 cm−1 is at least 0.05 and not higher than 3.

Abstract: A halogenobenzylaminopropionic acid derivative represented by the following formula (1): 1

Abstract: The present invention relates to an N-substituted benzothiophenesulfonamide derivative or a pharmaceutically acceptable salt thereof and applications thereof. Furthermore, it provides an agent for preventing or treating cardiac or circulatory disease and so on caused by abnormal increase of production of angiotensin II or endothelin I based on chymase activity, or by activation of mast cell, and an agent for preventing adhesion after surgery, wherein the agent has a selective inhibitory action on chymase.

Abstract: The present invention relates to a composite semipermeable membrane, which is useful as a reverse osmosis membrane or a nano-filtration membrane and comprises a polysulfone porous support membrane and a polyamide ultrathin layer formed on one of the surfaces of the porous support membrane, the composite membrane having the characteristic that in the infrared absorption spectrum obtained from the surface of a polyamide ultrathin layer of the composite semipermeable membrane, the ratio T (=Aa/As) of absorption intensity Aa at the absorption peak revealing C═O of polyamide in the region of 1600-1700 cm−1 to absorption intensity As at the absorption peak revealing polysulfone at a wavenumber around 1586 cm−1 is at least 0.05 and not higher than.

Abstract: The present invention relates to a compound of the formula [1′] 1

Abstract: The present invention relates to a compound of the formula [1′] wherein R2 is lower alkyl optionally substituted by hydroxy, amino and the like, ring B is phenyl, thienyl and the like, E is a single bond, —O—, —S— and the like, ring G is aryl, heterocyclic group and the like, R5 is halogen atom, hydroxy, lower alkyl optionally substituted by halogen atom etc., and the like, t is 0 or an integer of 1 to 5, when t is an integer of 2 to 5, each R5 may be the same or different, m is 0 or an integer of 1 to 8, and n is 0 or an integer of 1 to 4, and a nociceptin antagonist containing compound [1′] as an active ingredient. The compound [1′] shows, due to nociceptin antagonistic action, analgesic effect against sharp pain such as postoperative pain and the like. The present invention also relates to the use of certain amide derivative inclusive of compound [1′] as a nociceptin antagonist or analgesic.