Abstract: A irregularity analysis unit executes feature point extraction processing of extracting a plurality of feature points for each of a plurality of B-mode images acquired at different positions, and evaluation processing of generating information indicating irregularity of a tissue based on the feature points extracted for each of the plurality of B-mode images. The evaluation processing includes processing of executing distance evaluation processing of obtaining a feature point distance between a feature point of one B-mode image among two B-mode images and a feature point of the other B-mode image for each feature point in each of the two B-mode images, for each image pair including a reference B-mode image among the plurality of B-mode images and each of the other plurality of B-mode images, and processing of generating the information indicating the irregularity based on the feature point distance obtained for each feature point in each image pair.

Abstract: An information processing unit includes a Doppler measurement section that generates Doppler measurement information based on a reception Doppler signal output from a wall filter, and a machine learning model constructed based on training information and target information. The training information is information obtained from K reception Doppler signals. The target information is information obtained from J reception Doppler signals for the same measurement target object as that obtained from the K reception Doppler signals. Here, J and K are integers of 2 or more, and J is greater than K. The machine learning model generates the Doppler measurement information based on input information. The input information is information generated from the K reception Doppler signals for a measurement target object in a subject.

Abstract: A push wave transmission unit transmits a push wave to a biological tissue of a subject. A tracking wave transmission/reception unit transmits a tracking wave to the biological tissue and receives a reflected ultrasound wave reflected by the biological tissue. An elasticity analysis unit measures a propagation velocity of a shear wave generated in the biological tissue by the push wave and measures an elastic property of the biological tissue based on the propagation velocity, and measures the propagation velocity of the shear wave based on a measurement signal obtained by the reflected ultrasound wave received by the tracking wave transmission/reception unit. A controller determines whether to re-measure the elastic property according to an unnecessary component included in the measurement signal. When determining to re-measure the elastic property, the ultrasound diagnostic apparatus re-measures the elastic property by changing an acoustic property of the push wave according to the unnecessary component.

Abstract: Provided is an acoustic coupler capable of achieving both low elastic modulus and high deformability required for ultrasound imaging. The acoustic coupler is disposed between a probe for transmitting ultrasound waves and a subject, the acoustic coupler comprising a hydrogel including a copolymer that contains water. The copolymer comprises a monofunctional monomer having one ethylenically unsaturated group and a polyfunctional monomer having two to six ethylenically unsaturated groups. The molar ratio of the monofunctional monomer to the polyfunctional monomer is more than 90 and less than or equal to 3500.

Abstract: The invention provides an ultrasound imaging apparatus capable of highly accurately extracting a blood flow in a fine blood vessel in a short time. N pieces of frame data is generated by receiving ultrasound waves reflected by a subject with a plurality of transducers. A correlation matrix is generated based on a vector in which data at a corresponding position of the frame data is arranged for N frames, and a singular value and a singular vector for each of N ranks are calculated. A first filter element is calculated based on a variance between data at a corresponding position zx among a plurality of blood flow component frame data obtained by multiplying a plurality of the frame data by singular vectors at a threshold rank k or more. The second filter element is calculated based on the tissue component frame data obtained by multiplying the frame data by a singular vector at a rank 1.

Abstract: A data generation program is configured to cause a computing device to display, on a display, an oral cavity image three-dimensionally showing an oral cavity including a biological tissue, set, in the oral cavity image, a first spot indicating a top of a crown portion, a second spot indicating a top of an alveolar bone or a junction between a tooth and a gingiva, and a third spot indicating a root apex portion based on a user input or machine learning, and calculate a ratio between a first distance between the first spot and the second spot and a second distance between the second spot and the third spot.

Abstract: To provide an artificial bone having a porous structure with an improved affinity to osteogenic cells, an artificial bone (1) includes: a base material (2) containing porous ceramics provided with mutually interconnected multiple pores (6); a carbonaceous thin film (10) formed on an outer surface of the base material and wall surfaces (7) of the pores; and functional groups (13) including amino groups (12) provided on a surface and in an interior of the carbonaceous thin film.

Abstract: A data-generating apparatus includes: input processing circuitry configured to receive upper-jaw tooth row data showing a three-dimensional shape of a row of teeth in an upper jaw, lower-jaw tooth row data showing a three-dimensional shape of a row of teeth in a lower jaw, and jaw motion data showing a jaw motion; and generation processing circuitry configured to generate, based on the upper-jaw tooth row data, the lower-jaw tooth row data, and the jaw motion data, video data of at least one of the upper-jaw tooth row data and the lower-jaw tooth row data to which an indicator is added, the indicator indicating a positional relation between the row of teeth in the upper jaw and the row of teeth in the lower jaw, the positional relation changing in accordance with the jaw motion.

Abstract: A dental observation device by which, without displaying, in an overlapping manner, a visible light image of an image-capturing site in an oral cavity captured by a 3-D camera and 3-D image information on the image-capturing site in the oral cavity acquired in advance, an invisible portion in the visible light image is easily recognized. An observation system includes a visible light 3-D camera; a relative position calculator; a 3-D information storage storing 3-D image information acquired in advance; an image display displaying, side by side, a 2-D captured image captured by the visible light 3-D camera and 2-D converted image based on the 3-D image information corresponding to the surgical operation target site; and a display direction adjuster displaying, in the image display, the 2-D converted image in a predetermined direction on the basis of the image-capturing direction detected by the relative position calculator.

Abstract: A panoramic X-ray imaging apparatus includes: an X-ray generating unit; an X-ray detecting unit; a support that supports the X-ray generating unit and the X-ray detecting unit; a drive mechanism that turns at least the X-ray generating unit and the X-ray detecting unit by driving the support; a displacement mechanism that adds movement including a displacement component in a direction different from the turning to the X-ray detecting unit; a subject holding unit that holds an imaging subject; a turning controller that controls the turning by a drive mechanism and the displacement mechanism. The turning controller controls the drive mechanism and the displacement mechanism so as to add the movement avoiding the contact with the shoulder of the imaging subject during the turning of the X-ray generating unit and the X-ray detecting unit by the drive mechanism during the panoramic X-ray imaging.

Abstract: A support apparatus includes an input interface that receives input of image data showing a three-dimensional geometry of a biological tissue and a computing device that derives support information including information on positions of at least the tooth and the gingiva relative to each other, by using the image data inputted from the input interface and an estimation model for support of diagnosis of the state of disease in the biological tissue based on the image data, the estimation model being trained by machine learning to derive the support information.

Abstract: An object is to provide a drug which is useful in treating a nervous system disease. A drug containing vitamin B12 as an active ingredient according to the present invention has an M2 macrophage/microglia induction promoting effect, an M1 macrophage/microglia induction inhibiting effect, a nerve regeneration promoting effect, and the like and is very useful as a therapeutic agent for a nervous system disease, and particularly useful as a therapeutic agent for a central nervous system disease such as cerebral infarction, dementia, or spinal cord injury.

Abstract: A sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet including a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.

Abstract: To provide a power converter which can detect occurrence of excess current in early stage without providing a blanking time when the detection of excess current is not performed after the turn on of the switching device, and which can protect the power converter. A power converter includes a time change detection circuit that outputs a detection signal according to a time change rate of a main voltage; an excess current determination circuit that generates an excess current occurrence signal of normal current state when the detection signal is less than a first threshold value, and generates the excess current occurrence signal of excess current state when the detection signal is not less than the first threshold value; and a driving circuit that generates the driving voltage of OFF state when the drive command signal is ON state and the excess current occurrence signal is excess current state.

Abstract: A push wave transmission unit transmits a push wave to a biological tissue of a subject. A tracking wave transmission/reception unit transmits a tracking wave to the biological tissue and receives a reflected ultrasound wave reflected by the biological tissue. An elasticity analysis unit measures a propagation velocity of a shear wave generated in the biological tissue by the push wave and measures an elastic property of the biological tissue based on the propagation velocity, and measures the propagation velocity of the shear wave based on a measurement signal obtained by the reflected ultrasound wave received by the tracking wave transmission/reception unit. A controller determines whether to re-measure the elastic property according to an unnecessary component included in the measurement signal. When determining to re-measure the elastic property, the ultrasound diagnostic apparatus re-measures the elastic property by changing an acoustic property of the push wave according to the unnecessary component.

Abstract: An X-ray detection unit includes an X-ray detector that receives and detects the X-ray beam transmitted through the head. The support supports the X-ray generation unit and the X-ray detection unit. A drive mechanism moves the support such that the X-ray generation unit and the X-ray detection unit turn about an axis extending in a direction parallel to an apparatus vertical direction and around the head. An X-ray generation source moving unit moves the X-ray generation source in the apparatus vertical direction. The X-ray imaging apparatus increases a spread in the apparatus vertical direction of the X-ray beam when the X-ray generation source is located on an apparatus upper side, and decreases a spread in the apparatus vertical direction of the X-ray beam when the X-ray generation source is located on an apparatus lower side.

Abstract: A correlation matrix calculation unit calculates a correlation matrix Rzx for each data element of the frame data. A blood flow luminance image forming unit forms a blood flow extraction filter Pk,N on the basis of an eigenvalue ?i of a rank equal to or lower than a first threshold rank, the eigenvalue being obtained by singular value decomposition on the correlation matrix Rzx, and an eigenvector wi, wiH corresponding to the eigenvalue ?i and applies the blood flow extraction filter Pk,N to frame data F, therebyto forming a blood flow luminance image Uk,N. A tissue image forming unit forms a tissue image including tissue components on the basis of a signal value of each data element forming the plurality of pieces of the frame data. A blood flow extraction image forming unit subtracts the tissue image from the blood flow luminance image Uk, N, thereby forming a blood flow extraction image Uout.

Abstract: A data processing apparatus includes: an input portion configured to receive IOS data and CT data as an input, the IOS data being obtained by performing scanning by an intra oral scanner and including coordinate data of a point group indicating a surface shape of a tooth row including an IOS crown and an IOS gingiva, the CT data being obtained by performing capturing by a CT imaging device and including volume data of a CT crown; and processing circuitry. The processing circuitry replaces, in the CT data, a crown part of a CT tooth included in the CT data with which a shape of the IOS crown matches, with the IOS crown included in the IOS data, and performs synthesis in such a way that the IOS gingiva is arranged near the IOS crown after replacement.

Abstract: respective arms of three phases in each of which there are switching devices that are connected with a DC power source and an external connection point that is connected with a winding of an electric rotating machine, a phase current detection unit that detects a current of each of the three phases, and a switching control apparatus that controls the electric rotating machine by turning on or off the positive-polarity switching devices and the negative-polarity switching devices and that determines that an excessive current has occurred, in the case where a current detected by the phase current detection unit exceeds a predetermined threshold value, and then turns on any one of a group of all the positive-polarity switching devices and a group of all the negative-polarity switching devices and turns off the other one thereof.

Abstract: An object is to provide a drug which is useful in treating a nervous system disease. A drug containing vitamin B12 as an active ingredient according to the present invention has an M2 macrophage/microglia induction promoting effect, an M1 macrophage/microglia induction inhibiting effect, a nerve regeneration promoting effect, and the like and is very useful as a therapeutic agent for a nervous system disease, and particularly useful as a therapeutic agent for a central nervous system disease such as cerebral infarction, dementia, or spinal cord injury.