Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

Abstract: Numerous examples are disclosed of verification circuitry and associated methods in an artificial neural network. In one example, a system comprises a vector-by-matrix multiplication array comprising a plurality of non-volatile memory cells arranged in rows and columns, the non-volatile memory cells respectively capable of storing one of N possible levels corresponding to one of N possible currents, and a plurality of output blocks to receive current from respective columns of the vector-by-matrix multiplication array and generate voltages during a verify operation of the vector-by-matrix multiplication and generate digital outputs during a read operation of the vector-by-matrix multiplication.

Abstract: A system for identifying defects and measuring geometric dimensions in cosmetic ophthalmic lens immersed in a Saline solution, the system, comprising: a) at least one camera for obtaining images of the cosmetic ophthalmic lens, the camera having an optical axis; b) at least one electronically controlled illumination module designed with Visible and infrared LEDs, segmented accordingly and suitably integrated to be positioned along the vertical optical axis for directing light at different angles of the cosmetic ophthalmic lens; c) a customised glass cuvette designed with concave, concentric and spherical surfaces to avoid adding more optical power to the cosmetic ophthalmic lens under inspection and with the radius of the interior surface of the cuvette designed to be bigger than the lens to enable locating the cosmetic ophthalmic lens to the centre of the cuvette during inspection; d) a strobe controller integrated to the illumination module and Camera that is capable of capturing multiple images in quick su

Abstract: A resistive random access memory (RRAM) device is provided, and includes a top electrode layer, a bottom electrode layer, and an insulating layer positioned between the top electrode layer and the bottom electrode layer. The insulating layer includes a SiNx layer.

Abstract: In one example, a system comprises a vector-by-matrix multiplication array comprising non-volatile memory cells organized into rows and columns; a plurality of word lines coupled respectively to rows of the vector-by-matrix multiplication array; and a word line driver coupled to the plurality of word lines, the word line driver comprising a plurality of select transistors coupled to a common control line and the plurality of word lines, and a plurality of bias transistors coupled to the plurality of select transistors and capable of providing a bias voltage to a single select transistor in the plurality of select transistors or to all of plurality of select transistors in response to control signals.

Abstract: In one example, a neural network device comprises a first plurality of synapses configured to receive a first plurality of inputs and to generate therefrom a first plurality of outputs, wherein the first plurality of synapses comprises a plurality of memory cells, each of the plurality of memory cells configured to store a weight value corresponding to a number of electrons on its floating gate and the plurality of memory cells are configured to generate the first plurality of outputs based upon the first plurality of inputs and the stored weight values.

Abstract: Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, includes an occlusive device comprising a mesh having a low-profile state for intravascular delivery to the aneurysm and a deployed state, the mesh comprising a first end portion, a second end portion, and a length extending between the first and second end portions, and a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges. The mesh may have a predetermined shape in the deployed state in which (a) the mesh is curved along its width, (b) the mesh is curved along its length, and (c) the mesh has an undulating contour across at least a portion of one or both of its length or its width. The mesh is configured to be positioned within the aneurysm in the deployed state such that the mesh extends over the neck of the aneurysm.

Abstract: A matching making carrier service system and method that enables users to connect and collaborate on carrier services is described. The system provides a platform for users to search for each other for goods transportation purposes, such that a requester user and a traveler user can agree upon a freelance carrier service. The system may be configured to provide means to verify each user to provide reliable security of transactions between users. The system may be configured to provide escrow services to hold payment in secured means, such that payment may be configured to reliably provided upon completion of tasks. The platform may be configured to provide a feedback and review system such that users can be rated and ranked for the services rendered. The system may be configured to provide security encryption to ensure reliable interaction between users.

Abstract: Techniques are described for client registration for authorizing an aggregator service to access data on behalf of an application, through self-registration of an application client identifier and issuance of authorization token(s) based on the application client identifier. Implementations provide a technique for dynamic client registration that avoids the need for manual vetting and manual generation of the client credential grant. Additionally, the implementations described herein enforce domain values around the scope and/or purpose of the client grant. This allows for support of application providers through a single point of registration that supports multi-layer and channel. This also allows for support of a scalable authorization solution for any suitable number of clients. The dynamic client registration process adds an additional layer of security through the OAuth client grant and mutual authentication.

Abstract: Compositions for forming an improved vapor mitigation barrier are contemplated, such compositions being formed as an aqueous mixture of an asphalt component and a latex component, with the latex component including a chemically resistant latex, the chemically resistant latex being an acrylonitrile butadiene copolymer, an elastomeric fluoropolymer, or both. Such compositions, when cured and formed into a vapor mitigation barrier, may be seen to substantially mitigate diffusion of chlorinated hydrocarbons across the barriers. Also contemplated are methods for forming such vapor mitigation barriers, as well as vapor mitigation barrier products formed via the application of such compositions to various substrates.

Abstract: A recombinant Pichia pastoris strain which is genetically modified for highly expressing pediocin PA-1 and secreted into a medium so that the pediocin PA-1 is easily collected and purified from the culture medium. The obtained pediocin PA-1 has specific antimicrobial activities against Listeria monocytogenes ATCC 13932 and several other bacteria strains.

Abstract: Embodiments described herein disclose methods and systems for authorizing transactions received from client applications. The transaction request can include a first access token. After validating the first access token, the system can determine whether additional authentication is needed to authorize the transaction. If additional authentication is needed, the system can determine the authentication requirements. Once the additional authentication is received and verified, the system can generate a second access token and authorize the transaction by releasing the first access token.

Abstract: A system for administering transcranial magnetic stimulation to a subject is provided. The system includes a coil a controller, and a high-power switching module. The controller is configured to generate low voltage control signals for administering a treatment protocol via the coil. The high-power switching module is configured to generate a high voltage current delivered to the coil based on the low voltage control signals. In some embodiments, the high-power switching module includes a printed circuit board used to reduce intrinsic resistance and parasitic capacitance of the circuit such that the current delivered to the coil over a sequence of bursts remains stable. A new protocol for administering transcranial magnetic stimulation, referred to as high-density Theta Burst Stimulation (hdTBS), utilizes a pulse frequency of at least 40 Hz and a number of pulses per burst of four or greater.

Abstract: Illumination systems and methods of designing and construction of the same are disclosed. The resulting illumination systems comprising both Front and Back light modules, provides selectable and programmable illumination according to the requirements of the invention for optimal performance of enhancing defects on a multidimensional object. The light guides are suitably aligned to the Backlight module and mechanically integrated with spring loaded mechanisms to enable them to move freely and subsequently re-postion them to a reference home position as determined at the time of setup of the illumination assembly. The Front light module is utilised to highlight surface defects and mechanically integrated to the illumination system. The illumination modules, may include multiple discrete light emitting components of different spatial intensity distribution and color spectrum mounted in specific layout such that the application oriented combined illuminating effect is created.

Abstract: A method for generating a secret key at a first node for data communication between the first node and a second node. A channel estimate of a communication channel between the first and second nodes is obtained. A time-frequency matrix associated with the communication channel is then obtained based on the time-frequency transformation of the channel estimate. The secret key is then produced based on the time-frequency matrix. Furthermore, a corresponding key generator may be provided for generating a secret key.

Abstract: A labeling method includes determining whether there is an intersection between the first annotated segment and the second annotated segment; if Yes, determining whether the first annotated segment and the second annotated segment have different labels from each other; if Yes, sending the label of the first annotated segment to the second agent unit and the label of the second annotated segment to the first agent unit; if No, determining whether a discrepancy-over-union ratio between the first annotated segment and the second annotated segment is below a first threshold; if Yes, determining the intersection of the first annotated segment and the second annotated segment as a final annotated segment for the piece of time-series data; if No, assigning a review tag to a union segment of the piece of time-series data which has a duration from a start of the first annotated segment to an end of the second annotated segment.

Abstract: The method of processing and storing data for real time anomaly detection including steps: step 1: building a historical database over time, mean and standard deviation database; step 2: make a selection number of blocks and number of points in one block, divide historical data into equal-sized blocks and build formulas to calculate average, standard deviation of each data block and the whole data; Step 3: create a data mapping process that runs independently to read collected data, normalize data and interact with the in-memory database to write data history over time; step 4: perform data anomaly detection of new incoming data with mean, standard deviation of historical data already stored in database on read-only memory (RAM).

Abstract: Disclosed herein are novel 3D microelectrode arrays (3D MEA) that include a substrate body (e.g. chip), microneedles, traces, and a well, wherein the 3D MEA provides for transfer of electrical signals on one side of the substrate body to the other side of the substrate body. Methods for using 3D MEAs to grow electrogenic cells and obtain electrophysiological signals are disclosed as well. Fabrication techniques for producing the 3D MEAs are also disclosed.

Abstract: A method for producing a core-shell hybrid material made of an activated carbon core surrounded by a mesoporous silica sol-gel shell, the method including the formation of a mesoporous silica sol-gel shell around activated carbon particles. Also, the core-shell hybrid material formed by the method, and its use as a filtering material in filtering systems.

Abstract: Barriers for improved vapor mitigation are contemplated, such barriers being formed as a cured latex-asphalt mixture applied to the metal surface of a metallized substrate. The latex-asphalt mixture, prior to curing, comprises an emulsion of an asphalt component, a latex component, and water. Such barriers may be seen to substantially mitigate diffusion of chemical contaminants across the barriers in the form of gas or liquids. Also contemplated are methods for forming such barriers, whether fabricated off-site for installation on site, fabricated in-situ.