Patents by Inventor Hiroaki Ishihara
Hiroaki Ishihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20070141859Abstract: A laser processing process which comprises laser annealing a silicon film 2 ?m or less in thickness by irradiating a laser beam 400 nm or less in wavelength and being operated in pulsed mode with a pulse width of 50 nsec or more, and preferably, 100 nsec or more. A laser processing apparatus which comprises a laser generation device and a stage for mounting thereon a sample provided separately from said devices to thereby prevent transfer of vibration attributed to the movement of the stage to the laser generation device and the optical system. A stable laser beam can be obtained to thereby improve productivity.Type: ApplicationFiled: February 14, 2007Publication date: June 21, 2007Applicant: Semiconductor Energy Laboratory Co., Ltd.Inventors: Hiroaki Ishihara, Kazuhisa Nakashita, Hideto Ohnuma, Nobuhiro Tanaka, Hiroki Adachi
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Patent number: 7176283Abstract: Disclosed are cDNAs and genomic DNAs encoding protease-activated receptor 3 (PAR3) from mouse and human, and the recombinant polypeptides expressed from such cDNAs. The recombinant receptor polypeptides, receptor fragments and analogs expressed on the surface of cells are used in methods of screening candidate compounds for their ability to act as agonists or antagonists to the effects of interaction between thrombin and PAR3. Agonists are used as therapeutics to treat wounds, thrombosis, atherosclerosis, restenosis, inflammation, and other thrombin-activated disorders. Antagonists are used as therapeutics to control blood coagulation and thereby treating heart attack and stroke. Antagonists mediate inflammatory and proliferative responses to injury as occur in normal wound healing and variety of diseases including atherosclerosis, restenosis, pulmonary inflammation (ARDS) and glomerulosclerosis.Type: GrantFiled: December 8, 1998Date of Patent: February 13, 2007Assignee: The Regents of the University of CaliforniaInventors: Shaun R. Coughlin, Hiroaki Ishihara, Andrew Connolly
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Publication number: 20060194377Abstract: A laser annealing process for recovering crystallinity of a deposited semiconductor film such as of silicon which had undergone morphological damage, said process comprising activating the semiconductor by irradiating a pulsed laser beam operating at a wavelength of 400 nm or less and at a pulse width of 50 nsec or less onto the surface of the film, wherein, said deposited film is coated with a transparent film such as a silicon oxide film at a thickness of from 3 to 300 nm, and the laser beam incident to said coating is applied at an energy density E (mJ/cm2) provided that it satisfies the relation: log10N??0.02(E?350), where N is the number of shots of the pulsed laser beam.Type: ApplicationFiled: December 30, 2005Publication date: August 31, 2006Applicant: SEMICONDUCTOR ENERGY LABORATORY CO., LTD.Inventors: Shunpei Yamazaki, Hongyong Zhang, Hiroaki Ishihara
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Publication number: 20060189591Abstract: The present invention relates to a compound represented by formula (I): a salt of the compound, or a solvate of the compound or the salt; a drug containing any of the compounds, the salts, and the solvates; a preventive and/or therapeutic agent for an ischemic disease containing any of the compounds, the salts, and the solvates; and a platelet coagulation inhibitor containing any of the compounds, the salts, and the solvates. The compound of the present invention is useful as a strong platelet coagulation inhibitor without inhibiting COX-1 or COX-2.Type: ApplicationFiled: April 20, 2004Publication date: August 24, 2006Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Toru Okayama, Kouichi Uoto, Takashi Ishiyama, Naoaki Kanaya, Youichi Kimura, Hiroaki Ishihara, Toshiyuki Watanabe, Kunihiko Fujii
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Publication number: 20060128685Abstract: The present invention is directed to a strong platelet aggregation-inhibiting agent which does not inhibit COX-1 or COX-2. The present invention provides compounds represented by formula (I) or formula (II), salts of the compounds, and solvates of the compounds or the salts. Also provided are medicaments containing any of the compounds, salts, or solvates and preventive and/or therapeutic agents for ischemic diseases, containing any of the compounds, salts, or the solvates.Type: ApplicationFiled: February 6, 2004Publication date: June 15, 2006Applicant: DAIICHI PHARMACEUTICAL CO., LTD.,Inventors: Naoaki Kanaya, Hiroaki Ishihara, Youichi Kimura, Takashi Ishiyama, Yuichi Ochiai
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Patent number: 6991975Abstract: A laser annealing process for recovering crystallinity of a deposited semiconductor film such as of silicon which had undergone morphological damage, said process comprising activating the semiconductor by irradiating a pulsed laser beam operating at a wavelength of 400 nm or less and at a pulse width of 50 nsec or less onto the surface of the film, wherein, said deposited film is coated with a transparent film such as a silicon oxide film at a thickness of from 3 to 300 nm, and the laser beam incident to said coating is applied at an energy density E (mJ/cm2) provided that it satisfies the relation: log10N??0.02 (E?350), where N is the number of shots of the pulsed laser beam.Type: GrantFiled: November 23, 1998Date of Patent: January 31, 2006Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Shunpei Yamazaki, Hongyong Zhang, Hiroaki Ishihara
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Patent number: 6638800Abstract: A laser processing process which comprises laser annealing a silicon film 2 &mgr;m or less in thickness by irradiating at laser beam 400 nm or less in wavelength and being operated in pulsed mode with a pulse width of 50 nsec or more, and preferably, 100 nsec or more. A laser processing apparatus which comprises a laser generation device and a stage for mounting thereon a sample provided separately from said devices to thereby prevent transfer of vibration attributed to the movement of the stage to the laser generation device and the optical system. A stable laser beam can be obtained to thereby improve productivity.Type: GrantFiled: October 1, 1999Date of Patent: October 28, 2003Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Hiroaki Ishihara, Kazuhisa Nakashita, Hideto Ohnuma, Nobuhiro Tanaka, Hiroki Adachi
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Patent number: 6440785Abstract: A laser annealing process for recovering crystallinity of a deposited semiconductor film such as of silicon which had undergone morphological damage, said process comprising activating the semiconductor by irradiating a pulsed laser beam operating at a wavelength of 400 nm or less and at a pulse width of 50 nsec or less onto the surface of the film, wherein, said deposited film is coated with a transparent film such as a silicon oxide film at a thickness of from 3 to 300 nm, and the laser beam incident to said coating is applied at an energy density E (mJ/cm2) provided that it satisfies the relation: log10N≦−0.02(E−350), where N is the number of shots of the pulsed laser beam.Type: GrantFiled: July 12, 1999Date of Patent: August 27, 2002Assignee: Semiconductor Energy Laboratory Co., LtdInventors: Shunpei Yamazaki, Hongyong Zhang, Hiroaki Ishihara
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Patent number: 6002101Abstract: A method of manufacturing a semiconductor device by emitting a laser beam from an excimer laser, modifying an energy distribution by passing the beam through a lateral flyeye lens followed by a vertical flyeye lens, condensing the laser beam in two perpendicular sections by two cylindrical lenses to give the beam a rectangular shape, where the longer side can be in excess of 10 cm, then scanning the beam with a single direction over a semiconductor device.Type: GrantFiled: October 23, 1997Date of Patent: December 14, 1999Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Shunpei Yamazaki, Hongyong Zhang, Hiroaki Ishihara
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Patent number: 5968383Abstract: An excimer laser annealing apparatus with an optical system. The optical system includes a cylindrical concave lens (A), a cylindrical convex lens (B), a fly-eye lens (C) made of a cylindrical lens array provided in a lateral direction and a fly eye lens (D) made of a cylindrical lens array provided in a vertical direction. The laser light is changed from an initial gaussian distribution to a rectangular distribution by virtue of the fly-eye lenses. The laser beam then passes through cylindrical convex lenses (E and F) and is reflected by a mirror (G) and is focused on the specimen by a cylindrical lens (H). The homogenous rectangular beam created has a longer width than the specimen so that the specimen may only be moved along one direction.Type: GrantFiled: October 23, 1997Date of Patent: October 19, 1999Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Shunpei Yamazaki, Hongyong Zhang, Hiroaki Ishihara
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Patent number: 5897799Abstract: A laser processing apparatus including a laser device for emitting a first laser beam having a first cross section having a length and a width and an optical system for modifying the first laser beam to produce a second laser beam having a virtual focus. The second laser beam has a second cross section of which length is larger than the length of the first cross section and is constant with propagation of the second laser beam. The apparatus further includes a condenser located after the virtual focus for focusing the second laser beam on a specimen to be treated, wherein said second laser beam is condensed in only a widthwise direction of the cross section, and device for moving the specimen along the widthwise direction. Specifically, laser processing apparatus may include a laser device, a vertical fly-eye lens for homogenizing an intensity along a lengthwise direction of the first cross section, a mirror for directing the laser beam and cylindrical convex lens.Type: GrantFiled: June 11, 1996Date of Patent: April 27, 1999Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Shunpei Yamazaki, Hongyong Zhang, Hiroaki Ishihara
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Patent number: 5891764Abstract: A laser processing process which comprises laser annealing a silicon film 2 .mu.m or less in thickness by irradiating a laser beam 400 nm or less in wavelength and being operated in pulsed mode with a pulse width of 50 nsec or more, and preferably, 100 nsec or more.A laser processing apparatus which comprises a laser generation device and a stage for mounting thereon a sample provided separately from said device, to thereby prevent transfer of vibration attributed to the movement of the stage to the laser generation device and the optical system. A stable laser beam can be obtained to thereby improve productivity.Type: GrantFiled: October 30, 1996Date of Patent: April 6, 1999Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Hiroaki Ishihara, Kazuhisa Nakashita, Hideto Ohnuma, Nobuhiro Tanaka, Hiroki Adachi
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Patent number: 5892014Abstract: Disclosed are cDNAs and genomic DNAs encoding protease-activated receptor 3 (PAR3) from mouse and human, and the recombinant polypeptides expressed from such cDNAs. The recombinant receptor polypeptides, receptor fragments and analogs expressed on the surface of cells are used in methods of screening candidate compounds for their ability to act as agonists or antagonists to the effects of interaction between thrombin and PAR3. Agonists are used as therapeutics to treat wounds, thrombosis, atherosclerosis, restenosis, inflammation, and other thrombin-activated disorders. Antagonists are used as therapeutics to control blood coagulation and thereby treating heart attack and stroke. Antagonists mediate inflammatory and proliferative responses to injury as occur in normal wound healing and variety of diseases including atherosclerosis, restenosis, pulmonary inflammation (ARDS) and glomerulosclerosis.Type: GrantFiled: October 30, 1996Date of Patent: April 6, 1999Assignee: The Regents of the University of CaliforniaInventors: Shaun R. Coughlin, Hiroaki Ishihara, Andrew Connolly
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Patent number: 5858473Abstract: A laser annealing process for recovering crystallinity of a deposited semiconductor film such as of silicon which had undergone morphological damage, said process comprising activating the semiconductor by irradiating a pulsed laser beam operating at a wavelength of 400 nm or less and at a pulse width of 50 nsec or less onto the surface of the film, wherein,said deposited film is coated with a transparent film such as a silicon oxide film at a thickness of from 3 to 300 nm, and the laser beam incident to said coating is applied at an energy density E (mJ/cm.sup.2) provided that it satisfies the relation:log.sub.10 N.ltoreq.-0.02(E-350),where N is the number of shots of the pulsed laser beam.Type: GrantFiled: September 6, 1996Date of Patent: January 12, 1999Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Shunpei Yamazaki, Hongyong Zhang, Hiroaki Ishihara
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Patent number: 5643801Abstract: A laser processing process which includes laser annealing a silicon film 2 .mu.m or less in thickness by irradiating a laser beam 400 nm or less in wavelength and being operated in pulsed mode with a pulse width of 50 nsec or more and preferably, 100 nsec or more. The invention further relates to a laser processing apparatus which includes a laser generation device and a stage for mounting thereon a sample provide separately from said device, to thereby prevent transfer of vibration attributed to the movement of the stage to the laser generation device and the optical system. A stable laser beam can be obtained to thereby improve productivity.Type: GrantFiled: August 4, 1995Date of Patent: July 1, 1997Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Hiroaki Ishihara, Kazuhisa Nakashita, Hideto Ohnuma, Nobuhiro Tanaka, Hiroki Adachi