Abstract: An object of the present invention is to realize a combustion control device that reduces, when a pressure within a mixer is rapidly increased at the time of ignition of the combustion control device, the transmission of the temporarily increased pressure to a pressure sensor, that brings the pressure sensor into a non-operated state and that thereby can continue combustion in the combustion control device. Hence, a combustion control device is provided that includes: a combustion chamber which has a heat dissipation disc on a front surface and within which a combustion room is formed; a burner which is attached to the combustion chamber; a mixer which mixes a gas supplied to the burner with air; and a pressure sensor which is connected to the mixer through a pressure passage, where a pressure propagation delay means which reduces transmission to the pressure sensor caused by a temporary pressure increase within the mixer is provided partway along the pressure passage.

Abstract: The present invention relates to novel crystal forms of 2-amino-N-[2-(3a-(R)-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo[4,3-c]pyridin-5-yl)-1-(R)-benzyloxymethyl-2-oxo-ethyl]-isobutyramide L-tartrate. More particularly, the invention relates to polymorph forms, and to processes for the preparation of compositions containing and to uses of such polymorph forms.

Abstract: The present invention relates to novel crystal forms of 2-amino-N-[2-(3a-(R)-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo[4,3-c]pyridin-5-yl)-1-(R)-benzyloxymethyl-2-oxo-ethyl]-isobutyramide L-tartrate. More particularly, the invention relates to polymorph forms, and to processes for the preparation of compositions containing and to uses of such polymorph forms.

Abstract: The present invention relates to novel crystal forms of 2-amino-N-[2-(3a-(R)-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo[4,3-c]pyridin-5-yl)-1-(R)-benzyloxymethyl-2-oxo-ethyl]-isobutyramide L-tartrate. More particularly, the invention relates to polymorph forms, and to processes for the preparation of compositions containing and to uses of such polymorph forms.

Abstract: A brake caliper (10) includes a first caliper arm (12) that opposes a first frictional surface (6a) of a vehicle wheel (5) and a second caliper arm (14) that opposes a second frictional surface (6b) of the same. A movable brake pad (7) is supported by the first caliper arm (12) and applies a braking force to the first frictional surface (6a). A plurality of pistons (55) which drive the movable brake pad (7) in accordance with expansion of a diaphragm (75) provided in the brake caliper (10), and a guide member (65) that guides displacement of the plurality of pistons (55) in a right-angle direction relative to the first frictional surface (6a) are provided, and therefore the movable brake pad (7) applies an even braking force to the vehicle wheel (5) in cooperation with a fixed brake pad (700) fixed to the second caliper arm (14).

Abstract: An ultrasonic probe for supporting spine surgery serving as a tissue insertion type ultrasonic probe comprises an insertion unit and an operation unit. On a front end portion of the insertion unit, a tactile member and a transducer unit are provided. The insertion unit comprises a pipe, and a sheath tube provided outside of the pipe. An FPC board serving as a line sheet is provided in the pipe. The FPC board is inserted in a rounded shape similar to a tube along an inner wall surface of the pipe. A large number of signal lines are formed on the FPC board through printing. A ground cable is provided in an inside space of the FPC board. In the operation unit, a rear end portion of the FPC board and a front end portion of another FPC board are connected by thermo compression bonding.

Abstract: An object of the present invention is to realize a combustion control device that reduces, when a pressure within a mixer is rapidly increased at the time of ignition of the combustion control device, the transmission of the temporarily increased pressure to a pressure sensor, that brings the pressure sensor into a non-operated state and that thereby can continue combustion in the combustion control device. Hence, a combustion control device is provided that includes: a combustion chamber which has a heat dissipation disc on a front surface and within which a combustion room is formed; a burner which is attached to the combustion chamber; a mixer which mixes a gas supplied to the burner with air; and a pressure sensor which is connected to the mixer through a pressure passage, where a pressure propagation delay means which reduces transmission to the pressure sensor caused by a temporary pressure increase within the mixer is provided partway along the pressure passage.

Abstract: The present invention relates to a use of a compound having ghrelin receptor agonistic activity, a pharmaceutically acceptable salt thereof or a pharmaceutical composition thereof for the manufacture of a medicament for treatment of diseases including achlorhydria in which abnormal gastric acid secretion is involved. In addition, the present invention relates to the method of treatment including administering to a human or animal. The compound, the pharmaceutically acceptable salt thereof, or pharmaceutical compositions containing them, may be used in combination with one or more second active agents. Further, the present invention relates to pharmaceutical compositions and kits comprising a compound of the present invention or a pharmaceutically acceptable salt thereof for the treatment of said diseases.

Abstract: There is provided an ultrasonic probe for supporting spine surgery which can execute both inspection by tactile sense and inspection by ultrasound diagnosis. A front-end component provided at a front end of an insertion unit. The front-end component comprises a metal component and a resin component, and the metal component comprises a tactile member and an anchor. The resin component comprises a cap portion and a surrounding portion. An insertion portion in the front-end component is inserted into a front end portion of a pipe. The anchor and the front end portion are in close proximity with a certain distance therebetween, such that insulation is secured and vibration transmitted from a head can be transmitted from the anchor to the pipe in a superior manner.

Abstract: Disclosed is an insulating resin sheet laminate (an insulating resin sheet with a film or a metal foil) including an insulating resin layer with a uniform thickness that is formed without repulsion or unevenness in a process of forming the insulating resin layer on a film or a metal foil, and a multi-layer printed circuit board that includes the insulating resin sheet laminate and possesses high insulating reliability. The present invention provides an insulating resin sheet laminate (an insulating resin sheet with a film or a metal foil) obtained by forming an insulating resin layer made of a resin composition on a film or a metal foil, and the resin composition includes an acrylic surfactant.

Abstract: Medical diagnostic instruments and systems are provided that include (i) a proximal handle configured and dimensioned to permit an operator to manually grasp the instrument; (ii) an ultrasound probe including a longitudinal shaft extending distally from the handle and terminating in a distal end, and an ultrasound transducer mounted with respect to the longitudinal shaft proximate the distal end thereof, the ultrasound transducer including an array of ultrasonic energy generation elements; and (iii) a tactile feeler probe mounted with respect to the ultrasound probe, the tactile feeler probe including a longitudinal shaft mounted with respect to the longitudinal shaft of the ultrasound probe and extending distally beyond the distal end thereof, and a feeler probe tip (e.g., a ball tip) defined at a distal end of the longitudinal shaft of the tactile feeler probe. Advantageous methods for use of the disclosed instruments and systems are also provided, e.g.

Abstract: Medical diagnostic instruments/systems are provided that include (i) a proximal handle configured and dimensioned to permit an operator to manually grasp the instrument; (ii) an ultrasound probe including a longitudinal shaft extending distally from the handle and terminating in a distal end, and an ultrasound transducer mounted with respect to the longitudinal shaft, the ultrasound transducer including an array of ultrasonic energy generation elements (iii) a tactile feeler probe mounted with respect to the ultrasound probe; and (iv) at least one hollow receiver member mounted with respect to the longitudinal shaft of the ultrasound probe, the at least one hollow receiver member configured to receive a K-wire to permit the instrument to be slidably mounted thereto for purposes of guiding the ultrasound and tactile feeler probes axially relative to a desired anatomical location. Advantageous methods for use of the disclosed instruments/systems are also provided.

Abstract: There is provided an ultrasonic probe for supporting spine surgery which can execute both inspection by tactile sense and inspection by ultrasound diagnosis. A front-end component provided at a front end of an insertion unit. The front-end component comprises a metal component and a resin component, and the metal component comprises a tactile member and an anchor. The resin component comprises a cap portion and a surrounding portion. An insertion portion in the front-end component is inserted into a front end portion of a pipe. The anchor and the front end portion are in close proximity with a certain distance therebetween, such that insulation is secured and vibration transmitted from a head can be transmitted from the anchor to the pipe in a superior manner.

Abstract: An ultrasonic probe for supporting spine surgery serving as a tissue insertion type ultrasonic probe comprises an insertion unit and an operation unit. On a front end portion of the insertion unit, a tactile member and a transducer unit are provided. The insertion unit comprises a pipe, and a sheath tube provided outside of the pipe. An FPC board serving as a line sheet is provided in the pipe. The FPC board is inserted in a rounded shape similar to a tube along an inner wall surface of the pipe. A large number of signal lines are formed on the FPC board through printing. A ground cable is provided in an inside space of the FPC board. In the operation unit, a rear end portion of the FPC board and a front end portion of another FPC board are connected by thermo compression bonding.

Abstract: The present disclosure relates generally to equipment and procedures in the field of surgery and/or diagnostics and, more particularly, to instruments, systems, and methods for undertaking surgical and/or diagnostic procedures that involve and/or are in proximity to the brain, e.g., cranial procedures and/or surgery. The disclosed devices generally include a handle member and an elongated probe that includes an ultrasound transducer. The devices may be used in conjunction with K-wires/guidewires, tubular members, e.g., EVD catheters and/or ventricular drains, endoscopes/cameras, and accessory items such as curettes, probes, knives, suction devices, scissors, cautery units, forceps, grasping devices and the like.

Abstract: Medical diagnostic instruments/systems are provided that include (i) a proximal handle configured and dimensioned to permit an operator to manually grasp the instrument; (ii) an ultrasound probe including a longitudinal shaft extending distally from the handle and terminating in a distal end, and an ultrasound transducer mounted with respect to the longitudinal shaft, the ultrasound transducer including an array of ultrasonic energy generation elements (iii) a tactile feeler probe mounted with respect to the ultrasound probe; and (iv) at least one hollow receiver member mounted with respect to the longitudinal shaft of the ultrasound probe, the at least one hollow receiver member configured to receive a K-wire to permit the instrument to be slidably mounted thereto for purposes of guiding the ultrasound and tactile feeler probes axially relative to a desired anatomical location. Advantageous methods for use of the disclosed instruments/systems are also provided.

Abstract: Medical diagnostic instruments and systems are provided that include (i) a proximal handle configured and dimensioned to permit an operator to manually grasp the instrument; (ii) an ultrasound probe including a longitudinal shaft extending distally from the handle and terminating in a distal end, and an ultrasound transducer mounted with respect to the longitudinal shaft proximate the distal end thereof, the ultrasound transducer including an array of ultrasonic energy generation elements; and (iii) a tactile feeler probe mounted with respect to the ultrasound probe, the tactile feeler probe including a longitudinal shaft mounted with respect to the longitudinal shaft of the ultrasound probe and extending distally beyond the distal end thereof, and a feeler probe tip (e.g., a ball tip) defined at a distal end of the longitudinal shaft of the tactile feeler probe. Advantageous methods for use of the disclosed instruments and systems are also provided, e.g.

Abstract: Disclosed is an insulating resin sheet laminate (an insulating resin sheet with a film or a metal foil) including an insulating resin layer with a uniform thickness that is formed without repulsion or unevenness in a process of forming the insulating resin layer on a film or a metal foil, and a multi-layer printed circuit board that includes the insulating resin sheet laminate and possesses high insulating reliability. The present invention provides an insulating resin sheet laminate (an insulating resin sheet with a film or a metal foil) obtained by forming an insulating resin layer made of a resin composition on a film or a metal foil, and the resin composition includes an acrylic surfactant.

Abstract: A brake caliper (10) includes a first caliper arm (12) that opposes a first frictional surface (6a) of a vehicle wheel (5) and a second caliper arm (14) that opposes a second frictional surface (6b) of the same. A movable brake pad (7) is supported by the first caliper arm (12) and applies a braking force to the first frictional surface (6a). A plurality of pistons (55) which drive the movable brake pad (7) in accordance with expansion of a diaphragm (75) provided in the brake caliper (10), and a guide member (65) that guides displacement of the plurality of pistons (55) in a right-angle direction relative to the first frictional surface (6a) are provided, and therefore the movable brake pad (7) applies an even braking force to the vehicle wheel (5) in cooperation with a fixed brake pad (700) fixed to the second caliper arm (14).