Abstract: This invention provides compounds, compositions and methods for modulating the expression of human GST-? using RNA interference. The RNA interference molecules can be used in methods for preventing or treating diseases such as malignant tumor. Provided are a range of siRNA structures, having one or more of nucleotides being modified or chemically-modified. Advantageous structures include siRNAs with 2?-deoxy nucleotides located in the seed region, as well as other nucleotide modifications.

Abstract: The present invention provides a connector includes a housing having a fitting opening for the object to be connected, signal contacts retained in the housing in parallel disposition, a pressure member capable of pressing the signal contacts, and power source contacts. The power source contacts are retained besides the signal contacts, have a thickness dimension larger than that of the signal contacts and are to be pressed by the pressure member together with the signal contacts. The power source contacts include a power source contact with a fixation function, having not only the power source connection function but also a function of temporally fixing the object to be connected at a correct insertion position with respect to the signal contacts as well as a function of clamping and fixing the object to be connected in a state of being pressed by the pressure member.

Abstract: This invention provides compounds, compositions and methods for modulating the expression of human p21 using RNA interference. The RNA interference molecules can be used in methods for preventing or treating diseases such as malignant tumor. Provided are a range of siRNA structures, having one or more nucleotides being modified or chemically-modified. Advantageous structures include siRNAs with 2?-deoxy nucleotides located in the seed region, as well as other nucleotide modifications.

Abstract: A triaxial magnetic sensor that can detect with high precision magnetic fields in three axial directions comprises a substrate having a first surface and a second surface opposite the first surface, and a magnetic sensor element group provided on the first surface. The magnetic sensor element group includes a first magnetic sensor element for magnetic detection in the x-axis direction, a second magnetic sensor element for magnetic detection in the y-axis direction and a third magnetic sensor element for magnetic detection in the z-axis direction. The first through third magnetic sensor elements respectively contain first through third magneto-resistive effect elements composed of laminated bodies including at least a magnetization fixed layer and a free layer, and the magnetization direction of each of the magnetization fixed layers of the first through third magneto-resistive elements is fixed in a direction inclined at a prescribed angle with respect to the first surface.

Abstract: A timepiece part has a substrate; and a first coating made from a material containing Co and including greater than or equal to 26 wt % and less than or equal to 30 wt % Cr, and greater than or equal to 5 wt % and less than or equal to 7 wt % Mo. The substrate is preferably made from a material including at least one of stainless steel and Ti. A second coating made of a material including at least one of TiC and TiCN is preferably disposed between the substrate and first coating.

Abstract: Provided are: a targeting molecule targeting a target cell which is selected from the group consisting of a stellate cell, a myofibroblast, a cancer-associated fibroblast, a tumor cell and a cell expressing STRA6, said targeting molecule being selected from the group consisting of (1) a peptide containing an amino acid sequence in the cell-binding region of RBP, (2) a variant peptide of the aforesaid peptide (1), said variant peptide having a comparable targetability to peptide (1), and (3) a peptide mimetic having a comparable targetability to peptide (1) or peptide (2); a targeting agent, a carrier, a complex and a medicinal composition each comprising the targeting molecule; a method for treating, examining, diagnosing or monitoring a disease related to the aforesaid target cell; a method for labeling, detecting or imaging the target cell, etc.

Abstract: A connector includes a required number of contacts, an electrical insulation housing and a metallic shell. A tab is formed in the connector. A pressure receiving portion of the tab is pushed by a pushing portion of the shell to move the pressure receiving portion toward a mounting face of a substrate for applying a force in the insertion of FPC but not applying a force to the tab in the detaching thereof, whereby an engaging portion of the tab is moved in a direction opposing to the mounting face of the substrate to unfasten the engaging portion from an locking portion of the FPC.

Abstract: A base multilayer body is made by laminating a seed layer and a buffer layer in respective order. The seed layer is an alloy layer containing tantalum (Ta) and at least one type of other metal, and having an amorphous structure or a microcrystal structure. The buffer layer is an alloy layer having a [001] plane orientation hexagonal close-packed structure and containing at least one type of a group VI metal and at least one type of a group IX metal in the periodic table. With this configuration, a magnetic layer providing a desired magnetic characteristic(s) can be laminated on the thinned base multilayer body.

Abstract: An image processing apparatus includes: a processing unit that executes a process related to an image; an acquisition unit that acquires a first key and a second key including a restriction condition; a transition unit that transitions from a first operation mode to a second operation mode when the first key is acquired; a counting unit that counts usage of the processing unit; and a restricting unit that restricts execution of the process by the processing unit in the second operation mode according to a relationship between the counted usage and the restriction condition included in the acquired second key.

Abstract: The present invention provides a multi-can type gas turbine combustor including a plurality of combustors that mix and burn fuel and the air, the combustors being connected by a crossfire tube assembly. The gas turbine cools the crossfire tube assembly without lowering the temperature of a combustion exhaust gas passing through the crossfire tube assembly and prevents thermal deformation and fire damage of the crossfire tube assembly. In a gas turbine according to the present invention, a guide ring that guides a current of the air is provided in a position opposed to air holes. One side end portion of an annular space configured between the guide ring and a crossfire tube assembly is opened to a space on the inside of the crossfire tube assembly. The other end portion is a closed end connected to a partition wall configuring the crossfire tube assembly. The length of an annular space between the air holes and the closed end is set to three times or more as large as the diameter of the air holes.

Abstract: An image processing device includes an association unit, a generation unit, an output unit, a reception unit, and a print unit. The association unit associates a first document image with a second image, the second image being an image of a reverse side of the first document image. The generation unit generates multiple images in accordance with a result of the association. The output unit outputs the multiple images generated by the generation unit. The reception unit receives a selection of an image output by the output unit, the selection being made by a user operation. The print unit prints the selected image.

Abstract: A connector includes a required number of contacts, an electrical insulation housing and a metallic shell. A tab is formed in the connector. A pressure receiving portion of the tab is pushed by a pushing portion of the shell to move the pressure receiving portion toward a mounting face of a substrate for applying a force in the insertion of FPC but not applying a force to the tab in the detaching thereof, whereby an engaging portion of the tab is moved in a direction opposing to the mounting face of the substrate to unfasten the engaging portion from an locking portion of the FPC.

Abstract: A microwave assisted magnetic head includes a main magnetic pole; a trailing shield; and a spin torque oscillator provided between the main magnetic pole and the trailing shield. The spin torque oscillator has a first end surface configuring a part of an air bearing surface, a second end surface facing the main magnetic pole, and a third end surface facing the first end surface, the first angle ?1 made by the first end surface and the second end surface is smaller than the second angle ?2 formed by the second end surface and the third end surface, and the second angle ?2 is 80 to 100 degrees.

Abstract: A base multilayer body is made by laminating a seed layer and a buffer layer in respective order. The seed layer is an alloy layer containing tantalum (Ta) and at least one type of other metal, and having an amorphous structure or a microcrystal structure. The buffer layer is an alloy layer having a [001] plane orientation hexagonal close-packed structure and containing at least one type of a group VI metal and at least one type of a group IX metal in the periodic table. With this configuration, a magnetic layer providing a desired magnetic characteristic(s) can be laminated on the thinned base multilayer body.

Abstract: A microwave assisted magnetic head includes a main magnetic pole; a trailing shield; and a spin torque oscillator provided between the main magnetic pole and the trailing shield. The spin torque oscillator has a first end surface configuring a part of an air bearing surface, a second end surface facing the main magnetic pole, and a third end surface facing the first end surface, the first angle ?1 made by the first end surface and the second end surface is smaller than the second angle ?2 formed by the second end surface and the third end surface, and the second angle ?2 is 80 to 100 degrees.

Abstract: This invention provides compounds, compositions and methods for modulating the expression of human p21 using RNA interference. The RNA interference molecules can be used in methods for preventing or treating diseases such as malignant tumor. Provided are a range of siRNA structures, having one or more nucleotides being modified or chemically-modified. Advantageous structures include siRNAs with 2?-deoxy nucleotides located in the seed region, as well as other nucleotide modifications.

Abstract: One embodiment provides a solenoid valve. The solenoid valve includes a fixed core, a movable core and a coil. A first valve seat member and a second valve seat member are fixed in the fixed core, and a valve body member is disposed therebetween. A spring member is interposed between the valve body member and the second valve seat member such that the valve body member is normally seated on the first valve seat member. The valve body member can move away from the first valve seat member to be seated on the second valve seat member, by being pushed by the movable core. And, a guide member holds the valve body member and the spring member to the second valve seat member so as not to move away from the second valve seat member.

Abstract: There is provided a gas turbine combustor capable of improving cooling performance of a combustion chamber thereof and reducing the amount of NOx emissions.

Abstract: A front face side substrate provided between a supporting member and a receiving layer of a thermal transfer image-receiving sheet. The front face side substrate includes a front face side layer provided on one surface of a substrate layer and a rear face side layer provided on another surface of the substrate layer. The substrate layer includes (A) a propylene-based polymer, (B) calcium carbonate, and (C) titanium oxide, and the weight of (A) is 70% by weight to 94.5% by weight, the weight of (B) is 5% by weight to 28% by weight, and the weight of (C) is 0.5% by weight to 3% by weight, based on the assumption that the total weight of (A), (B) and (C) is 100% by weight. The front face side layer includes a modified propylene-based polymer, and the rear face side layer includes a propylene-based polymer.

Abstract: An image processing device includes an association unit, a generation unit, an output unit, a reception unit, and a print unit. The association unit associates a first document image with a second image, the second image being an image of a reverse side of the first document image. The generation unit generates multiple images in accordance with a result of the association. The output unit outputs the multiple images generated by the generation unit. The reception unit receives a selection of an image output by the output unit, the selection being made by a user operation. The print unit prints the selected image.