Abstract: This coated metal sheet for exterior covering has a metal sheet and a top coating layer disposed on the metal sheet, the top coating layer is configured from a fluororesin and contains a gloss control agent comprising 0.01-15 vol % of microporous particles and a matte agent comprising primary particles, and the coated metal sheet satisfies the belowmentioned formulae. In the number-based particle size distribution of the gloss control agent and the matte agent, R is the number average particle size (?m) of the gloss control agent, D197.5 and D297.5 represent the 97.5% particle size (?m) of the gloss control agent and the matte agent, Ru is the upper limit particle size (?m) of the gloss control agent, and T is the top coating layer thickness (?m). D197.5/T?0.9 Ru?1.2T R?1.0 0.5?D297.5/T?7.0 3?T?40.

Abstract: A wrapped textile sleeve for protecting an elongate member and method of construction thereof is provided. The sleeve includes an inner layer having opposite inner edges extending lengthwise between opposite inner ends. The opposite inner edges are laterally spaced from one another by an inner width. The sleeve further includes an outer layer having opposite outer edges extending lengthwise between opposite outer ends. The opposite outer edges are laterally spaced from one another by an outer width. An adhesive intermediate layer is sandwiched between the inner layer and the outer layer, wherein a melted portion of the adhesive intermediate bonds the inner layer to the outer layer. The adhesive intermediate layer extends beyond at least one of the inner edges to provide an exposed region of the adhesive intermediate layer. The exposed region is bonded to the outer layer and maintains the outer layer in a wrapped, tubular configuration.

Abstract: A mutated tryptophan oxidase suitable for practical implementation is described herein. Specifically, a mutated tryptophan oxidase wherein at least one amino acid residue of a wild-type tryptophan oxidase is mutated and, as a result, has higher tryptophan oxidase activity and/or stability as compared to the wild-type tryptophan oxidase. The mutated tryptophan oxidase can be derived from a wild-type tryptophan oxidase having at least one of Motifs (2), (3), (5), (7), (9), (11), (13), and (14), and at least one amino acid residue in any of these motifs can have mutation. The mutated tryptophan oxidase also can have a mutation of one or more amino acid residues in an amino acid sequence represented by SEQ ID NO: 2 and a sequence homologous thereto.

Abstract: A protective textile sleeve having enhanced end fray resistance and being adapted to be bonded to an elongate member extending therethrough, and method of construction thereof, are provided. The sleeve has a wall with a cavity bounded by an innermost surface extending between opposite open ends. A first material, including a hot melt adhesive material, facilitating bonding the wall to an outer surface of an elongate member extending therethrough, is bonded to the wall immediately adjacent the opposite ends, and a second material, facilitating prevention of end fray of the wall ends, including an elastomeric material is bonded to the wall immediately adjacent the opposite ends.

Abstract: A sheet discharge device includes a discharge roller, a first roller configured to form a first nip portion by contacting the discharge roller, a second roller configured to form a second nip portion by contacting the discharge roller on a downstream side of the first roller in a rotation direction of the discharge roller, an urging unit configured to urge the first roller and the second roller toward the discharge roller, and an adjustment unit configured to adjust a ratio of a pressure of the second nip portion to a pressure of the first nip portion in a state in which the first roller and the second roller are kept in contact with the discharge roller by the urging unit, wherein a sheet is conveyed while being simultaneously held by the first nip portion and the second nip portion.

Abstract: A tool for fixing a protective textile sleeve about an elongate member contained therein and method of use thereof is provided. The tool includes a clamp assembly having opposed clamp members attached to one another for pivotal movement relative to one another between an open state and a closed state. The clamp members have clamping surfaces, wherein at least one of the clamping surfaces has at least one outlet. A fluid source is arranged in fluid communication with the at least one outlet, and a heat source is configured to heat fluid from the fluid source to create steam. The steam is dispensed outwardly from the at least one outlet to cause an adhesive on the sleeve to become activated to bond with an adjacent abutting surface.

Abstract: A sheet conveying device includes a blocking member having a blocking surface with which a leading end of a sheet that is being conveyed comes into contact for obliquity correction. The blocking member is rotated by being pushed by the sheet against an urging force of a positioning unit that positions the blocking member to be in the standby position. The blocking member is rotatable to be in a sheet-passage-allowing orientation in which the sheet is allowed to pass. When a trailing end of the sheet that is being conveyed has passed the blocking member, the blocking member that is in the sheet-passage-allowing orientation rotates in a same direction as a sheet conveyance direction and is positioned to be in a standby position.

Abstract: The present invention pertains to an imidazolylamide derivative represented by formula (1) that exhibits an exceptional suppressive effect on cancer cell sphere formation ability and that is useful as an antitumor agent that can be administered orally, or a pharmacologically acceptable salt thereof.

Abstract: A protective textile sleeve having enhanced end fray resistance and being adapted to be bonded to an elongate member extending therethrough, and method of construction thereof, are provided. The sleeve has a wall with a cavity bounded by an innermost surface extending between opposite open ends. A first material, including a hot melt adhesive material, facilitating bonding the wall to an outer surface of an elongate member extending therethrough, is bonded to the wall immediately adjacent the opposite ends, and a second material, facilitating prevention of end fray of the wall ends, including an elastomeric material is bonded to the wall immediately adjacent the opposite ends.

Abstract: The present invention provides a compound having TrkA inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention relates to a compound represented by Formula (I): wherein ?X is ?O or the like, R5 and R5A are hydrogen atoms or the like, -A- is —NR1— or the like, B is substituted or unsubstituted aromatic carbocyclyl or the like, R1 is substituted or unsubstituted alkyl or the like, R2 is a hydrogen atom or the like, —W— is —CH2— or the like, —WA— is —CH2— or the like, R13 is substituted or unsubstituted aromatic carbocyclyl or the like, R14 is substituted or unsubstituted aromatic heterocyclyl or the like, R15 is substituted or unsubstituted alkyl or the like, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same.

Abstract: A self-wrapping nonwoven sleeve for routing and protecting elongate members and method of construction thereof is provided. The sleeve includes a non-woven wall having a thickness extending between inner and outer sides. The wall has opposite edges extending along a length of the sleeve between opposite ends. The opposite edges are biased into a self-wrapped configuration by heat-set material of the nonwoven wall to define a tubular cavity. The non-woven wall includes first and second portions extending between the opposite edges. The first portion and second portion have respective first and second thicknesses extending between the inner and outer sides, wherein the first thickness is greater than the second thickness and wherein the first portion provides flexibility to the wall and the second portion is heat set to bias the wall into its self-wrapped configuration.

Abstract: A sheet conveyance apparatus conveying a sheet includes a conveyance roller and first and second rotary members. A first virtual line and a second virtual line cross each other when viewed in the rotation axis direction of the conveyance roller, with the first virtual line passing through the rotation center of a first longitudinal end of the first rotary member and a rotation center of a second longitudinal end of the first rotary member when viewed in the rotation axis direction of the conveyance roller. A second virtual line passes through the rotation center of a third longitudinal end of the second rotary member and the rotation center of a fourth longitudinal end of the second rotary member when viewed in the rotation axis direction of the conveyance roller.

Abstract: A protective textile sleeve having a flexible, tubular wall of braided yarns and method of construction thereof is provided. At least some of the yarns include plastically deformable and/or heat-settable monofilaments and/or multifilaments that are plastically deformed and/or heat-set to provide the wall with a convolute shape. The convolute shape is formed by a plurality of alternating crests and valleys, wherein the crests are formed in tight, axially compressed relation with one another, with the valleys intervening between the crests being relatively narrow or short in axially extending length relative to the crests, providing the wall with an increased density, an increased abrasion resistance, enhanced thermal protection, enhanced impact resistance, enhanced noise attenuation. Further, with the wall having an accordion-like shape, greatly enhanced flexibility is attained without concern of kinking when routing the sleeve about meandering paths and about sharp bends, corners and the like.

Abstract: The sheet conveyance apparatus includes first and second rollers, the second roller coming into contact with the first roller and thereby forming a nip portion, the second rotation axis being inclined with respect to the first rotation axis, wherein the second roller includes a first outer circumferential portion having a first outside diameter, a second outer circumferential portion arranged on one side of the first outer circumferential portion in an axial direction of the second rotation axis and having a second outside diameter larger than the first outside diameter, and a third outer circumferential portion arranged on the other side of the first outer circumferential portion, and wherein an outer circumferential surface of the first roller contacts with at least the first, second and third outer circumferential portions of the second roller, to form the nip portion.

Abstract: A coating material capable of forming a film that is free of squeakiness and is less likely to suffer staining of clothing dye on the surface of a base such as a rubber molded article. The coating material contains fluororesin primary particles having an average particle size of 0.2 to 200 nm, a curable silicone resin in an amount of 0.1 to 250 mass % relative to the fluororesin primary particles, and water.

Abstract: The present invention provides a compound having a TrkA inhibitory activity or a pharmaceutically acceptable salt thereof. The present invention relates to a compound represented by Formula (I): wherein -L- is —C(?X)—, or the like, —Z— is —NR5—, or the like, —ZA— is —NR5A—, or the like, B is substituted or unsubstituted aromatic carbocyclyl, or the like, Y is a single bond, or the like, the ring C is a substituted or unsubstituted aromatic heterocycle, or the like, R2 is a hydrogen atom, or the like, and the group represented by is a group represented by Formula: or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.

Abstract: A sheet conveyance apparatus includes a conveyance roller, a first rotary member forming a first nip portion conveying a sheet in a first conveyance direction, a rotation axis of the first rotary member being inclined with respect to a rotation axis of the conveyance roller such that a center of one end of the first rotary member is positioned at a different position in the first conveyance direction with respect to a center of the other end, and a second rotary member forming a second nip portion conveying a sheet in a second conveyance direction, a rotation axis of the second rotary member being inclined with respect to the rotation axis of the conveyance roller such that a center of one end of the second rotary member is positioned at a different position in the second conveyance direction with respect to a center of the other end.

Abstract: A separation member includes a contact surface contacting a photosensitive member when a transfer member is positioned at a second position, and a regulation unit that regulates a position of the separation member with respect to the photosensitive member, in which the regulation unit contacts the photosensitive member earlier than the contact surface in a process of inserting a cartridge in an apparatus main body.

Abstract: An electromagnetic interference (EMI) shield assembly and method of construction is provided. The assembly includes a body having a wall of warp knit nonmetallic yarn having opposite sides extending generally parallel with one another between opposite ends and a plurality of weft inserted metal wires. The wire is inserted to provide discrete bundles each arranged in side-by-side relation with one another and extending beyond the opposite sides of the wall to provide a plurality of exposed free ends. The nonmetallic yarn is looped about the wires, thereby fixing the wire relative to the nonmetallic yarn and to other wires in an optimal EMI shielding position. Metal brackets adapted for ready attachment to a source of electrical ground are attached to the exposed free ends. The individual bundles of wires extend parallel to one another, with a gap having a predetermined width extending between the adjacent bundles.

Abstract: A separation member includes a contact surface contacting a photosensitive member when a transfer member is positioned at a second position, and a regulation unit that regulates a position of the separation member with respect to the photosensitive member, in which the regulation unit contacts the photosensitive member earlier than the contact surface in a process of inserting a cartridge in an apparatus main body.