Patents by Inventor Hiroko Hagiwara

Hiroko Hagiwara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160145330
    Abstract: This invention provides a novel means that allows efficient secretion and production of a target protein in a host cell. This invention concerns a novel polypeptide having an activity of improving the secretion productivity of a target protein, a gene comprising a nucleotide sequence encoding such polypeptide, a vector comprising such gene, a transformant obtained by transforming a host cell with such vector, and a method for producing a protein comprising a step of culturing such transformant and recovering a target protein from the culture product.
    Type: Application
    Filed: June 25, 2014
    Publication date: May 26, 2016
    Applicants: KANEKA CORPORATON, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Teruyuki NISHI, Kiyoshi ASAI, Hiroko HAGIWARA, Masayuki MACHIDA
  • Publication number: 20150157264
    Abstract: An optical sensor includes: a light emitter; a light receiver; a rod-shaped grasping member in which one of the light emitter and the light receiver is disposed, and which is to be grasped by a hand of a subject; and a clamping member which is adapted to clamp a part of the hand of the subject with the grasping member, another one of the light emitter and the light receiver being disposed in the clamping member.
    Type: Application
    Filed: December 2, 2014
    Publication date: June 11, 2015
    Inventors: Naoki Kobayashi, Teiji Ukawa, Kazumasa Ito, Masahiro Takeuchi, Yoshinori Ueda, Hiroko Hagiwara
  • Publication number: 20150150513
    Abstract: A biological signal measuring system includes: first and second optical sensors attached to first and second body portions of a subject; a first average oxygen saturation acquiring section acquiring a first average value corresponding to an average value of the first oxygen saturation corresponding to an arterial oxygen saturation in the first body portion in a predetermined time period starting at a first time; a second average oxygen saturation acquiring section acquiring a second average value corresponding to an average value of the second oxygen saturation corresponding to an arterial oxygen saturation in the second body portion in the predetermined time period starting at a second time that is different from the first time; and a difference value acquiring section acquiring a difference value, to be displayed, between the first average value and the second average value.
    Type: Application
    Filed: December 2, 2014
    Publication date: June 4, 2015
    Inventors: Naoki Kobayashi, Teiji Ukawa, Kazumasa Ito, Masahiro Takeuchi, Yoshinori Ueda, Hiroko Hagiwara
  • Patent number: 8988227
    Abstract: An information processing apparatus and program having a reading unit configured to read a plurality of alarm information about alarms generated based on abnormalities of biological information of a patient or abnormalities of a medical apparatus, and a control unit configured to associate same alarm contents that are included in the different alarm information in terms of the alarm contents that indicate contents of abnormalities causing the generation of the alarms is provided.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: March 24, 2015
    Assignee: Nihon Kohden Corporation
    Inventors: Shinji Tezuka, Hiroko Hagiwara, Masahiro Echigo, Rie Muneshima
  • Publication number: 20140012096
    Abstract: Herein disclosed is a monitor, including: a measurement section that acquires measured values of a plurality of parameters showing a health state of a living body; a classification setting section that classifies a relationship among the measured values of the plurality of parameters into a plurality of types of detection states; a status setting section that respectively assigns any of a plurality of types of alarm statuses to the plurality of types of detection states; a state specifying section that specifies one of the plurality of types of detection states on the basis of the measured values acquired by the measurement section; and an annunciation section that outputs an alarm corresponding to the alarm status assigned to the specified detection state.
    Type: Application
    Filed: July 2, 2013
    Publication date: January 9, 2014
    Inventors: Ei Nomura, Masami Tanishima, Hiroko Hagiwara
  • Publication number: 20130231578
    Abstract: An electrocardiogram analysis report simultaneously displays an electrocardiogram waveform collected from a subject and information about a measurement value calculated from the electrocardiogram waveform. The electrocardiogram analysis report includes a frontal plane display region configured to display a limb leads waveform included in the electrocardiogram waveform and information about a measurement value calculated from the limb leads waveform, and a horizontal plane display region configured to display a chest lead waveform included in the electrocardiogram waveform and information about a measurement value calculated from the chest lead waveform, wherein the information about the measurement value is displayed at a position spaced apart by a distance corresponding to a size of the measurement value in a direction from a predetermined center point to the relevant lead waveform in the frontal plane display region and the horizontal plane display region.
    Type: Application
    Filed: February 19, 2013
    Publication date: September 5, 2013
    Applicant: Nihon Kohden Corporation
    Inventors: Tsuneo Takayanagi, Jiro Suto, Ryoko Kamiya, Teiji Ukawa, Hiroko Hagiwara, Rie Muneshima
  • Publication number: 20120249332
    Abstract: An information processing apparatus and program having a reading unit configured to read a plurality of alarm information about alarms generated based on abnormalities of biological information of a patient or abnormalities of a medical apparatus, and a control unit configured to associate same alarm contents that are included in the different alarm information in terms of the alarm contents that indicate contents of abnormalities causing the generation of the alarms is provided.
    Type: Application
    Filed: March 29, 2012
    Publication date: October 4, 2012
    Applicant: Nihon Kohden Corporation
    Inventors: Shinji TEZUKA, Hiroko Hagiwara, Masahiro Echigo, Rie Muneshima
  • Publication number: 20110054328
    Abstract: A biological information monitor includes: a first measuring unit which measures a pulse wave propagation time of a patient; a second measuring unit which measures a blood pressure of the patient; a calculating unit which calculates an estimated blood pressure value of the patient based on the pulse wave propagation time of the patient; a setting unit which sets a threshold; and a determining unit which compares the estimated blood pressure value with the threshold. The second measuring unit is activated to measure the blood pressure of the patient at least one of at time intervals and at a time when an operator operates the second measuring unit, and the second measuring unit is activated to measure the blood pressure of the patient by the determining unit based on the comparison result.
    Type: Application
    Filed: August 31, 2010
    Publication date: March 3, 2011
    Applicant: NIHON KOHDEN CORPORATION
    Inventors: Mitsushi HYOGO, Teiji UKAWA, Yoshihiro SUGO, Hiroko HAGIWARA
  • Publication number: 20070243604
    Abstract: A DNA fragment prepared by inserting a translation termination codon into 5? upstream side of the active site of a lethal gene, a transformant selection marker which uses the same, and a vector into which the marker is inserted. Since this lethal gene is used as a gene marker, complete extinction of transformants having no exogenous gene can be achieved, and a transformant selection marker capable of effecting stable amplification of a vector containing an exogenous gene in a host can be obtained. In addition, a vector which can effect accurate and efficient gene analyses by DNA microarray and the like is obtained.
    Type: Application
    Filed: July 28, 2003
    Publication date: October 18, 2007
    Inventors: Masayuki Machida, Haruhiko Masaki, Sumiko Kunihiro, Hiroko Hagiwara
  • Publication number: 20060099602
    Abstract: In order to achieve an object of providing a nucleic acid library and a protein library capable of supplying plural species of proteins correlated with the nucleic acid coding therefor at once, and analyzing immediately after the supply the plural species of protein in parallel, the present invention provides a nucleic acid library comprising not less than two species of library units present in a state in which they are separated from one another, wherein each library unit comprises a nucleic acid that can express not less than one species of protein in an in vitro transcription/translation system or an in vitro translation system, and a first protein trapper that is set contiguously to the nucleic acid, each library unit is set on the surface of a solid support, and the nucleic acid contained in each library unit is immobilized on the surface of the solid support where each library unit is set, and a protein library obtainable by subjecting at once not less than two species of library units possessed by the
    Type: Application
    Filed: September 29, 2004
    Publication date: May 11, 2006
    Applicants: Precision System Science Co., Ltd., National Institute of Advanced Industrial Science and Technology
    Inventors: Hideji Tajima, Masayuki Machida, Hiroko Hagiwara, Sumiko Kunihiro
  • Publication number: 20040096857
    Abstract: In relation to a multiple inspection multiplexing method and a suspension for multiple inspection multiplexing, it is an object to provide multiple inspection multiplexing method and a suspension for multiple inspection multiplexing which by performing inspections of multiple types together in parallel, processing can be performed efficiently both timewise and spacewise, and since the same conditions can be set for inspections of each type, inspections of high reliability can be conducted.
    Type: Application
    Filed: December 29, 2003
    Publication date: May 20, 2004
    Inventors: Masayuki Machida, Hiroko Hagiwara, Hideji Tajima