Patents by Inventor Hiroshi Awaji
Hiroshi Awaji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8357522Abstract: The present invention provides a novel material useful for selectively isolating a cell such as monocyte and the like or a protein from a body fluid and a production method thereof, a physiological material using the material and an isolation material using the physiological material, as well as a method of harvesting a cell such as monocyte and the like using the isolation material, a method of harvesting a protein and a method of preparing a dendritic cell.Type: GrantFiled: May 25, 2007Date of Patent: January 22, 2013Assignee: Kaneka CorporationInventors: Hiroshi Awaji, Ashutosh Kumar, Akira Kobayashi, Naohiro Imai
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Publication number: 20120322133Abstract: The present invention provides a novel material useful for selectively isolating a cell such as monocyte and the like or a protein from a body fluid and a production method thereof, a physiological material using the material and an isolation material using the physiological material, as well as a method of harvesting a cell such as monocyte and the like using the isolation material, a method of harvesting a protein and a method of preparing a dendritic cell.Type: ApplicationFiled: February 23, 2012Publication date: December 20, 2012Applicant: KANEKA CORPORATIONInventors: Hiroshi AWAJI, Ashutosh KUMAR, Akira KOBAYASHI, Naohiro IMAI
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Publication number: 20120156749Abstract: The present invention provides a novel material useful for selectively isolating a cell such as monocyte and the like or a protein from a body fluid and a production method thereof, a physiological material using the material and an isolation material using the physiological material, as well as a method of harvesting a cell such as monocyte and the like using the isolation material, a method of harvesting a protein and a method of preparing a dendritic cell.Type: ApplicationFiled: February 23, 2012Publication date: June 21, 2012Applicant: KANEKA CORPORATIONInventors: Hiroshi AWAJI, Ashutosh KUMAR, Akira KOBAYASHI, Naohiro IMAI
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Publication number: 20090312452Abstract: This invention provides a novel optionally acylated cyclic tetrasaccharide-containing polyurethane derivative and a process for producing the same, and a novel cyclic tetrasaccharide modified polyurethane foam and a simple process for producing the same. Specifically, the present invention provides a polyurethane derivative containing an optionally acylated cyclic tetrasaccharide: cyclo{?6)-?-D-glucopyranosyl-(1?3)-?-D-glucopyranosyl-(1?-6)-?-D-glucopyranosyl-(1?3)-?-D-glucopyranosyl-(1?}, a process for producing polyurethane, comprising reacting an acylated cyclic tetrasaccharide and a diol compound with a diisocyanete compound, a process for producing a cyclic tetrasaccharide-containing polyurethane, comprising hydrolyzing the polyurethane, a process for producing a polyurethane foam, comprising reacting polyol with polyisocyanete in the presence of the cyclic tetrasaccharide and foaming the reaction product, and a cyclic tetrasaccharide modified polyurethane foam produced by the production process.Type: ApplicationFiled: September 29, 2006Publication date: December 17, 2009Applicants: KANEKA CORPORATION, KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJOInventors: Hiroshi Awaji, Ashutosh Kumar
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Publication number: 20090306325Abstract: A novel polyurethane derivative which is thermoplastic and excellent in thermoformability to a film or a tube and a process for producing the same are provided. Further, a biocompatible material with less blood platelet adhesion is provided. A linear oligosaccharide- or an acylated linear oligosaccharide-containing polyurethane derivative, and a process for producing a linear oligosaccharide-containing polyurethane obtained by reacting a linear oligosaccharide and a diol compound with a diisothiocyanate compound, and a process for producing an acylated linear oligosaccharide-containing polyurethane obtained by acylating the linear oligosaccharide-containing polyurethane. The biocompatible material characterized by using the linear oligosaccharide-containing polyurethane.Type: ApplicationFiled: January 26, 2007Publication date: December 10, 2009Applicant: KANEKA CORPORATIONInventors: Hiroshi Awaji, Ashutosh Kumar
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Publication number: 20090239300Abstract: The present invention provides a novel material useful for selectively isolating a cell such as monocyte and the like or a protein from a body fluid and a production method thereof, a physiological material using the material and an isolation material using the physiological material, as well as a method of harvesting a cell such as monocyte and the like using the isolation material, a method of harvesting a protein and a method of preparing a dendritic cell.Type: ApplicationFiled: May 25, 2007Publication date: September 24, 2009Applicant: KANEKA CORPORATIONInventors: Hiroshi Awaji, Ashutosh Kumar, Akira Kobayashi, Naohiro Imai
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Patent number: 6964814Abstract: A film is provided which comprises a thermoplastic resin A having a substituted or non-substituted imide group at a side chain of the resin A, and a thermoplastic resin B having a substituted or non-substituted phenyl group and a nitrile group at a side chain of the resin B. The film has a retardation value of 0 to 1000 nm, a light transmission of 85% or more, and a haze of 2% or less.Type: GrantFiled: December 8, 2004Date of Patent: November 15, 2005Assignee: Kaneka CorporationInventors: Sadao Fujii, Toshihiko Hikida, Shigeru Tanaka, Hirosuke Kawabata, Hiroshi Awaji
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Publication number: 20050096431Abstract: A film is provided which comprises a thermoplastic resin A having a substituted or non-substituted imide group at a side chain of the resin A, and a thermoplastic resin B having a substituted or non-substituted phenyl group and a nitrile group at a side chain of the resin B. The film has a retardation value of 0 to 1000 nm, a light transmission of 85% or more, and a haze of 2% or less.Type: ApplicationFiled: December 8, 2004Publication date: May 5, 2005Inventors: Sadao Fujii, Toshihiko Hikida, Shigeru Tanaka, Hirosuke Kawabata, Hiroshi Awaji
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Patent number: 6150535Abstract: The present invention has its object to provide a process for producing azetidine-2-carboxylic acid and an intermediate thereof, which is efficient and economical and suited for industrial practice.The present invention is related to a process for producing azetidine-2-carboxylic acid of the following formula (5), which comprises subjecting a 4-oxo-2-azetidinecarboxylic acid derivative represented by the general formula (1) to hydride reduction to give azetidine-2-methanol of the following formula (2), treating the same with an amino-protecting agent to give N-protected azetidine-2-methanol represented by the following general formula (3), treating this with an oxidizing agent to give N-protected azetidine-2-carboxylic acid represented by the following general formula (4) and, further, subjecting the amino-protecting group thereof to elimination.Type: GrantFiled: December 30, 1999Date of Patent: November 21, 2000Assignee: Kaneka CorporationInventors: Hiroshi Awaji, Shingo Matsumoto, Kenji Inoue, Kazuhiko Matsuo
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Patent number: 5744630Abstract: The present invention has for its object to provide an efficient and economical method for producing an 3-amino-2-hydroxy-1-propanol derivative and an oxazolidinone derivative derived therefrom, both of which are of use as intermediates for the production of drugs including HIV protease inhibitors.The invention relates to a method for producing an 3-amino-2-hydroxy-1-propanol derivative of general formula (2) ##STR1## (wherein R.sup.1 represents alkyl, aralkyl or aryl; R.sup.2 and R.sup.3 independently represent hydrogen or an amino-protecting group, provided, however, that both R.sup.2 and R.sup.3 are not concurrently hydrogen) and an oxazolidinone derivative derived therefrom.Type: GrantFiled: July 18, 1995Date of Patent: April 28, 1998Assignee: Kaneka CorporationInventors: Kenji Inoue, Hiroshi Awaji, Satomi Takahashi
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Patent number: 5391797Abstract: A process for preparing an alkoxysilane of the general formula:R.sup.3.sub.b SiH.sub.c (OR.sup.2).sub.4-(b+c)in which R.sup.2 represents a substituted or unsubstituted alkyl group, R.sup.3 represents a monovalent substituted or unsubstituted hydrocarbon group, b is 1, 2 or 3, and c is 0, 1, or 2, having the step of:reacting an alkoxysilane of the general formula:R.sup.1.sub.a Si(OR.sup.2).sub.4-awherein R.sup.1 represents a monovalent substituted or unsubstituted hydrocarbon group, R.sup.2 is the same as defined above, and a is 0, 1, 2 or 3, with a polysiloxane in the presence of a catalyst containing an aluminum alkoxide, a zirconium alkoxide or a zirconium chelate to obtain the alkoxysilane, which process suppresses side reactions to provide the intended compound which is free from halogen compounds in a high yield.Type: GrantFiled: March 31, 1994Date of Patent: February 21, 1995Assignee: Kanegafuchi Chemical Industry Co., Ltd.Inventors: Toshifumi Hirose, Katsuya Ouchi, Hiroshi Awaji
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Patent number: 5171829Abstract: A copolymeric amphiphilic polyimide precursor having the recurring unit of the formula (1): ##STR1## wherein R.sup.1 is a tetravalent group having at least 2 carbon atoms, R.sup.2 is a bivalent group having at least 2 carbon atoms, and R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are hydrogen atom or a monovalent group having 1 to 30 carbon atoms selected from the group consisting of an aliphatic group, an alicyclic group, an aromatic group, a group in which an aliphatic group is combined with an aromatic group, or an alicyclic group, and their groups substituted by a halogen atom, nitro group, amino group, cyano group, methoxy group or acetoxyl group, provided that at least one of R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is neither hydrogen atom nor the above-mentioned group which has 1 to 11 carbon atoms; a part of at least one of said R.sup.1 and said R.sup.2 being substituted with a group having a valence different therefrom.Type: GrantFiled: January 16, 1991Date of Patent: December 15, 1992Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Masakazu Uekita, Hiroshi Awaji
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Patent number: 5071694Abstract: A multi-layer resist comprising (A) a layer of a Langmuir-Blodgett film, (B) a layer of at least one thin film and (C) a substrate, said layer (B) being placed between said layer, (A) and said substrate (C). The multi-layer resists of the invention are applicable to ultra fine processing on the order of submicron, half-micron or quarter-micron, and the number of defects can be remarkably decreased.Type: GrantFiled: February 20, 1990Date of Patent: December 10, 1991Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Masakazu Uekita, Hiroshi Awaji, Satoshi Mizunuma
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Patent number: 5072262Abstract: An electric-electronic device including a polyimide thin film is disclosed, said polyimide thin film having a thickness of not more than 1000 .ANG. and a dielectric breakdown strength of not less than 1.times.10.sup.6 V/cm. The device has excellent performance properties ascribed to high heat resistance, mechanical strength, chemical resistance and insulating properties of the polyimide thin film.Type: GrantFiled: October 10, 1989Date of Patent: December 10, 1991Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Masakazu Uekita, Hiroshi Awaji
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Patent number: 5071733Abstract: A patterned thin film suitable for use in electric and electronic devices, prepared from a polymer or a mixture of the polymer and other known compounds capable of forming a thin film by LB technique, said polymer having linear recurring units wherein an organic group R.sup.1 having at least 2 carbon atoms and a valence of at least 2 is combined alternately with an organic group R.sup.2 having at least 2 carbon atoms and a valence of at least 2 through a bivalent group formed by a reaction of an acid group A containing a hetero atom and a basic group B containing a hetero atom, and wherein a hydrocarbon-containing group R.sup.3 having 10 to 30 carbon atoms which may contain a substituent group, is linked by covalent or ionic bond to said recurring units, the number of groups R.sup.3 being at least 2 per 10 recurring units.Type: GrantFiled: December 29, 1989Date of Patent: December 10, 1991Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Masakazu Uekita, Hiroshi Awaji, Makoto Murata, Satoshi Mizunuma
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Patent number: 5043248Abstract: A photosensitive amphiphilic high polymer comprises a linear recurring unit containing at least divalent 1st organic group (R.sup.1) having at least two carbon atoms and at least divalent 2nd organic group (R.sup.2) having at least two carbon atoms, said organic groups R.sup.1 and R.sup.2 being connected to each other by a divalent linkage group formed by a reaction of an acid group (A) containing a hetero atom and a basic group (B) containing a hetero group; and at least one hydrocarbon-containing group having 10 to 30 carbon atoms, which may have a substituent, bonded to said recurring unit by a covalent bond or an ionic bond; and a dimerizable or polymerizable unsaturated bond or an orthonitrobenzyl group ##STR1## which may have a substituent, contained in a part or the whole of said recurring unit.Type: GrantFiled: October 25, 1989Date of Patent: August 27, 1991Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Masakazu Uekita, Hiroshi Awaji
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Patent number: 4988795Abstract: An amphiphilic polyimide precursor having at least 70% by mole of the recurring unit of the formula (1): ##STR1## wherein R.sup.1 is a tetravalent group having at least 2 carbon atoms, R.sup.2 is a bivalent group having at least 2 carbon atoms, and R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are hydrogen atom or a monovalent group having 1 to 30 carbon atoms selected from an aliphatic group, an alicyclic group, an aromatic group, a group in which an aliphatic group is combined with an alicyclic group or an aromatic group, and their groups substituted by a halogen atom, nitro group, amino group, cyano group, methoxy group or acetoxyl group, provided that at least one, preferably at least two, of R.sup.3, R.sup.4, R.sup.5 and R.sup.Type: GrantFiled: September 7, 1989Date of Patent: January 29, 1991Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Masakazu Uekita, Hiroshi Awaji
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Patent number: 4987219Abstract: A copolymeric amphiphilic polyimide precursor having the recurring unit of the formula (1): ##STR1## wherein R.sup.1 is a tetravalent group having at least 2 carbon atoms, R.sup.2 is a bivalent group having at least 2 carbon atoms, and R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are hydrogen atom or a monovalent group having 1 to 30 carbon atoms selected from the group consisting of an aliphatic group, an alicyclic group, an aromatic group, a group in which an aliphatic group is combined with an aromatic group, or an alicyclic group, and their groups substituted by a halogen atom, nitro group, amino group, cyano group, methoxy group or acetoxyl group, provided that at least one of R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is neither hydrogen atom nor the above-mentioned group which has 1 to 11 carbon atoms; a part of at least one of said R.sup.1 and said R.sup.2 being substituted with a group having a valence different therefrom.Type: GrantFiled: April 22, 1987Date of Patent: January 22, 1991Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Masakazu Uekita, Hiroshi Awaji
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Patent number: 4954608Abstract: A copolymerized polyamic acid salt having a recurring unit represented by following formula (I) and (II) and the process for preparing thereof. ##STR1## wherein (A) or (A') represents a formula ##STR2## wherein, R.sup.1 represents a tetravalent group having at least 2 carbon atoms; R.sup.2 represents a divalent group having at least 2 carbon atoms; and R.sup.31, R.sub.32, R.sup.33, R.sup.41, R.sup.42, R.sup.43, R.sup.5, and R.sup.6 each represents a monovalent group having 1 to 30 carbon atoms selected from an aliphatic group, an alicyclic group, an aromatic group, a group in which an aliphatic group is combined with an alicyclic group or an aromatic group, each of these groups substituted by a halogen atom, a nitro group, an amino group, a cyano group, a methoxy group, or an acetoxy group, or a hydrogen atom; at least one of said R.sup.31, R.sup.32, R.sup.33, R.sup.41, R.sup.42, R.sup.43, R.sup.5 and R.sup.Type: GrantFiled: June 1, 1987Date of Patent: September 4, 1990Assignee: Kanegafuchi Kagaku Kogyo KabushikiInventors: Masakazu Uekita, Hiroshi Awaji
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Patent number: 4943471Abstract: A patterned thin film suitable for use in electric and electronic devices, prepared from a polymer or a mixture of the polymer and other known compounds capable of forming a thin film by LB technique, said polymer having linear recurring units wherein an organic group R.sup.1 having at least 2 carbon atoms and a valence of at least 2 is combined alternately with an organic group R.sup.2 having at least 2 carbon atoms and a valence of at least 2 through a bivalent group formed by a reaction of an acid group A containing a hetero atom and a basic group B containing a hetero atom, and wherein a hydrocarbon-containing group R.sup.3 having 10 to 30 carbon atoms which may contain a substituent group, is linked by covalent or ionic bond to said recurring units, the number of groups R.sup.3 being at least 2 per 10 recurring units.Type: GrantFiled: September 23, 1988Date of Patent: July 24, 1990Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Masakazu Uekita, Hiroshi Awaji, Makoto Murata, Satoshi Mizunuma