Patents by Inventor Hiroshi Awaji

Hiroshi Awaji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8357522
    Abstract: The present invention provides a novel material useful for selectively isolating a cell such as monocyte and the like or a protein from a body fluid and a production method thereof, a physiological material using the material and an isolation material using the physiological material, as well as a method of harvesting a cell such as monocyte and the like using the isolation material, a method of harvesting a protein and a method of preparing a dendritic cell.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: January 22, 2013
    Assignee: Kaneka Corporation
    Inventors: Hiroshi Awaji, Ashutosh Kumar, Akira Kobayashi, Naohiro Imai
  • Publication number: 20120322133
    Abstract: The present invention provides a novel material useful for selectively isolating a cell such as monocyte and the like or a protein from a body fluid and a production method thereof, a physiological material using the material and an isolation material using the physiological material, as well as a method of harvesting a cell such as monocyte and the like using the isolation material, a method of harvesting a protein and a method of preparing a dendritic cell.
    Type: Application
    Filed: February 23, 2012
    Publication date: December 20, 2012
    Applicant: KANEKA CORPORATION
    Inventors: Hiroshi AWAJI, Ashutosh KUMAR, Akira KOBAYASHI, Naohiro IMAI
  • Publication number: 20120156749
    Abstract: The present invention provides a novel material useful for selectively isolating a cell such as monocyte and the like or a protein from a body fluid and a production method thereof, a physiological material using the material and an isolation material using the physiological material, as well as a method of harvesting a cell such as monocyte and the like using the isolation material, a method of harvesting a protein and a method of preparing a dendritic cell.
    Type: Application
    Filed: February 23, 2012
    Publication date: June 21, 2012
    Applicant: KANEKA CORPORATION
    Inventors: Hiroshi AWAJI, Ashutosh KUMAR, Akira KOBAYASHI, Naohiro IMAI
  • Publication number: 20090312452
    Abstract: This invention provides a novel optionally acylated cyclic tetrasaccharide-containing polyurethane derivative and a process for producing the same, and a novel cyclic tetrasaccharide modified polyurethane foam and a simple process for producing the same. Specifically, the present invention provides a polyurethane derivative containing an optionally acylated cyclic tetrasaccharide: cyclo{?6)-?-D-glucopyranosyl-(1?3)-?-D-glucopyranosyl-(1?-6)-?-D-glucopyranosyl-(1?3)-?-D-glucopyranosyl-(1?}, a process for producing polyurethane, comprising reacting an acylated cyclic tetrasaccharide and a diol compound with a diisocyanete compound, a process for producing a cyclic tetrasaccharide-containing polyurethane, comprising hydrolyzing the polyurethane, a process for producing a polyurethane foam, comprising reacting polyol with polyisocyanete in the presence of the cyclic tetrasaccharide and foaming the reaction product, and a cyclic tetrasaccharide modified polyurethane foam produced by the production process.
    Type: Application
    Filed: September 29, 2006
    Publication date: December 17, 2009
    Applicants: KANEKA CORPORATION, KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO
    Inventors: Hiroshi Awaji, Ashutosh Kumar
  • Publication number: 20090306325
    Abstract: A novel polyurethane derivative which is thermoplastic and excellent in thermoformability to a film or a tube and a process for producing the same are provided. Further, a biocompatible material with less blood platelet adhesion is provided. A linear oligosaccharide- or an acylated linear oligosaccharide-containing polyurethane derivative, and a process for producing a linear oligosaccharide-containing polyurethane obtained by reacting a linear oligosaccharide and a diol compound with a diisothiocyanate compound, and a process for producing an acylated linear oligosaccharide-containing polyurethane obtained by acylating the linear oligosaccharide-containing polyurethane. The biocompatible material characterized by using the linear oligosaccharide-containing polyurethane.
    Type: Application
    Filed: January 26, 2007
    Publication date: December 10, 2009
    Applicant: KANEKA CORPORATION
    Inventors: Hiroshi Awaji, Ashutosh Kumar
  • Publication number: 20090239300
    Abstract: The present invention provides a novel material useful for selectively isolating a cell such as monocyte and the like or a protein from a body fluid and a production method thereof, a physiological material using the material and an isolation material using the physiological material, as well as a method of harvesting a cell such as monocyte and the like using the isolation material, a method of harvesting a protein and a method of preparing a dendritic cell.
    Type: Application
    Filed: May 25, 2007
    Publication date: September 24, 2009
    Applicant: KANEKA CORPORATION
    Inventors: Hiroshi Awaji, Ashutosh Kumar, Akira Kobayashi, Naohiro Imai
  • Patent number: 6964814
    Abstract: A film is provided which comprises a thermoplastic resin A having a substituted or non-substituted imide group at a side chain of the resin A, and a thermoplastic resin B having a substituted or non-substituted phenyl group and a nitrile group at a side chain of the resin B. The film has a retardation value of 0 to 1000 nm, a light transmission of 85% or more, and a haze of 2% or less.
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: November 15, 2005
    Assignee: Kaneka Corporation
    Inventors: Sadao Fujii, Toshihiko Hikida, Shigeru Tanaka, Hirosuke Kawabata, Hiroshi Awaji
  • Publication number: 20050096431
    Abstract: A film is provided which comprises a thermoplastic resin A having a substituted or non-substituted imide group at a side chain of the resin A, and a thermoplastic resin B having a substituted or non-substituted phenyl group and a nitrile group at a side chain of the resin B. The film has a retardation value of 0 to 1000 nm, a light transmission of 85% or more, and a haze of 2% or less.
    Type: Application
    Filed: December 8, 2004
    Publication date: May 5, 2005
    Inventors: Sadao Fujii, Toshihiko Hikida, Shigeru Tanaka, Hirosuke Kawabata, Hiroshi Awaji
  • Patent number: 6150535
    Abstract: The present invention has its object to provide a process for producing azetidine-2-carboxylic acid and an intermediate thereof, which is efficient and economical and suited for industrial practice.The present invention is related to a process for producing azetidine-2-carboxylic acid of the following formula (5), which comprises subjecting a 4-oxo-2-azetidinecarboxylic acid derivative represented by the general formula (1) to hydride reduction to give azetidine-2-methanol of the following formula (2), treating the same with an amino-protecting agent to give N-protected azetidine-2-methanol represented by the following general formula (3), treating this with an oxidizing agent to give N-protected azetidine-2-carboxylic acid represented by the following general formula (4) and, further, subjecting the amino-protecting group thereof to elimination.
    Type: Grant
    Filed: December 30, 1999
    Date of Patent: November 21, 2000
    Assignee: Kaneka Corporation
    Inventors: Hiroshi Awaji, Shingo Matsumoto, Kenji Inoue, Kazuhiko Matsuo
  • Patent number: 5744630
    Abstract: The present invention has for its object to provide an efficient and economical method for producing an 3-amino-2-hydroxy-1-propanol derivative and an oxazolidinone derivative derived therefrom, both of which are of use as intermediates for the production of drugs including HIV protease inhibitors.The invention relates to a method for producing an 3-amino-2-hydroxy-1-propanol derivative of general formula (2) ##STR1## (wherein R.sup.1 represents alkyl, aralkyl or aryl; R.sup.2 and R.sup.3 independently represent hydrogen or an amino-protecting group, provided, however, that both R.sup.2 and R.sup.3 are not concurrently hydrogen) and an oxazolidinone derivative derived therefrom.
    Type: Grant
    Filed: July 18, 1995
    Date of Patent: April 28, 1998
    Assignee: Kaneka Corporation
    Inventors: Kenji Inoue, Hiroshi Awaji, Satomi Takahashi
  • Patent number: 5391797
    Abstract: A process for preparing an alkoxysilane of the general formula:R.sup.3.sub.b SiH.sub.c (OR.sup.2).sub.4-(b+c)in which R.sup.2 represents a substituted or unsubstituted alkyl group, R.sup.3 represents a monovalent substituted or unsubstituted hydrocarbon group, b is 1, 2 or 3, and c is 0, 1, or 2, having the step of:reacting an alkoxysilane of the general formula:R.sup.1.sub.a Si(OR.sup.2).sub.4-awherein R.sup.1 represents a monovalent substituted or unsubstituted hydrocarbon group, R.sup.2 is the same as defined above, and a is 0, 1, 2 or 3, with a polysiloxane in the presence of a catalyst containing an aluminum alkoxide, a zirconium alkoxide or a zirconium chelate to obtain the alkoxysilane, which process suppresses side reactions to provide the intended compound which is free from halogen compounds in a high yield.
    Type: Grant
    Filed: March 31, 1994
    Date of Patent: February 21, 1995
    Assignee: Kanegafuchi Chemical Industry Co., Ltd.
    Inventors: Toshifumi Hirose, Katsuya Ouchi, Hiroshi Awaji
  • Patent number: 5171829
    Abstract: A copolymeric amphiphilic polyimide precursor having the recurring unit of the formula (1): ##STR1## wherein R.sup.1 is a tetravalent group having at least 2 carbon atoms, R.sup.2 is a bivalent group having at least 2 carbon atoms, and R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are hydrogen atom or a monovalent group having 1 to 30 carbon atoms selected from the group consisting of an aliphatic group, an alicyclic group, an aromatic group, a group in which an aliphatic group is combined with an aromatic group, or an alicyclic group, and their groups substituted by a halogen atom, nitro group, amino group, cyano group, methoxy group or acetoxyl group, provided that at least one of R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is neither hydrogen atom nor the above-mentioned group which has 1 to 11 carbon atoms; a part of at least one of said R.sup.1 and said R.sup.2 being substituted with a group having a valence different therefrom.
    Type: Grant
    Filed: January 16, 1991
    Date of Patent: December 15, 1992
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masakazu Uekita, Hiroshi Awaji
  • Patent number: 5071694
    Abstract: A multi-layer resist comprising (A) a layer of a Langmuir-Blodgett film, (B) a layer of at least one thin film and (C) a substrate, said layer (B) being placed between said layer, (A) and said substrate (C). The multi-layer resists of the invention are applicable to ultra fine processing on the order of submicron, half-micron or quarter-micron, and the number of defects can be remarkably decreased.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: December 10, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masakazu Uekita, Hiroshi Awaji, Satoshi Mizunuma
  • Patent number: 5072262
    Abstract: An electric-electronic device including a polyimide thin film is disclosed, said polyimide thin film having a thickness of not more than 1000 .ANG. and a dielectric breakdown strength of not less than 1.times.10.sup.6 V/cm. The device has excellent performance properties ascribed to high heat resistance, mechanical strength, chemical resistance and insulating properties of the polyimide thin film.
    Type: Grant
    Filed: October 10, 1989
    Date of Patent: December 10, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masakazu Uekita, Hiroshi Awaji
  • Patent number: 5071733
    Abstract: A patterned thin film suitable for use in electric and electronic devices, prepared from a polymer or a mixture of the polymer and other known compounds capable of forming a thin film by LB technique, said polymer having linear recurring units wherein an organic group R.sup.1 having at least 2 carbon atoms and a valence of at least 2 is combined alternately with an organic group R.sup.2 having at least 2 carbon atoms and a valence of at least 2 through a bivalent group formed by a reaction of an acid group A containing a hetero atom and a basic group B containing a hetero atom, and wherein a hydrocarbon-containing group R.sup.3 having 10 to 30 carbon atoms which may contain a substituent group, is linked by covalent or ionic bond to said recurring units, the number of groups R.sup.3 being at least 2 per 10 recurring units.
    Type: Grant
    Filed: December 29, 1989
    Date of Patent: December 10, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masakazu Uekita, Hiroshi Awaji, Makoto Murata, Satoshi Mizunuma
  • Patent number: 5043248
    Abstract: A photosensitive amphiphilic high polymer comprises a linear recurring unit containing at least divalent 1st organic group (R.sup.1) having at least two carbon atoms and at least divalent 2nd organic group (R.sup.2) having at least two carbon atoms, said organic groups R.sup.1 and R.sup.2 being connected to each other by a divalent linkage group formed by a reaction of an acid group (A) containing a hetero atom and a basic group (B) containing a hetero group; and at least one hydrocarbon-containing group having 10 to 30 carbon atoms, which may have a substituent, bonded to said recurring unit by a covalent bond or an ionic bond; and a dimerizable or polymerizable unsaturated bond or an orthonitrobenzyl group ##STR1## which may have a substituent, contained in a part or the whole of said recurring unit.
    Type: Grant
    Filed: October 25, 1989
    Date of Patent: August 27, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masakazu Uekita, Hiroshi Awaji
  • Patent number: 4988795
    Abstract: An amphiphilic polyimide precursor having at least 70% by mole of the recurring unit of the formula (1): ##STR1## wherein R.sup.1 is a tetravalent group having at least 2 carbon atoms, R.sup.2 is a bivalent group having at least 2 carbon atoms, and R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are hydrogen atom or a monovalent group having 1 to 30 carbon atoms selected from an aliphatic group, an alicyclic group, an aromatic group, a group in which an aliphatic group is combined with an alicyclic group or an aromatic group, and their groups substituted by a halogen atom, nitro group, amino group, cyano group, methoxy group or acetoxyl group, provided that at least one, preferably at least two, of R.sup.3, R.sup.4, R.sup.5 and R.sup.
    Type: Grant
    Filed: September 7, 1989
    Date of Patent: January 29, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masakazu Uekita, Hiroshi Awaji
  • Patent number: 4987219
    Abstract: A copolymeric amphiphilic polyimide precursor having the recurring unit of the formula (1): ##STR1## wherein R.sup.1 is a tetravalent group having at least 2 carbon atoms, R.sup.2 is a bivalent group having at least 2 carbon atoms, and R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are hydrogen atom or a monovalent group having 1 to 30 carbon atoms selected from the group consisting of an aliphatic group, an alicyclic group, an aromatic group, a group in which an aliphatic group is combined with an aromatic group, or an alicyclic group, and their groups substituted by a halogen atom, nitro group, amino group, cyano group, methoxy group or acetoxyl group, provided that at least one of R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is neither hydrogen atom nor the above-mentioned group which has 1 to 11 carbon atoms; a part of at least one of said R.sup.1 and said R.sup.2 being substituted with a group having a valence different therefrom.
    Type: Grant
    Filed: April 22, 1987
    Date of Patent: January 22, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masakazu Uekita, Hiroshi Awaji
  • Patent number: 4954608
    Abstract: A copolymerized polyamic acid salt having a recurring unit represented by following formula (I) and (II) and the process for preparing thereof. ##STR1## wherein (A) or (A') represents a formula ##STR2## wherein, R.sup.1 represents a tetravalent group having at least 2 carbon atoms; R.sup.2 represents a divalent group having at least 2 carbon atoms; and R.sup.31, R.sub.32, R.sup.33, R.sup.41, R.sup.42, R.sup.43, R.sup.5, and R.sup.6 each represents a monovalent group having 1 to 30 carbon atoms selected from an aliphatic group, an alicyclic group, an aromatic group, a group in which an aliphatic group is combined with an alicyclic group or an aromatic group, each of these groups substituted by a halogen atom, a nitro group, an amino group, a cyano group, a methoxy group, or an acetoxy group, or a hydrogen atom; at least one of said R.sup.31, R.sup.32, R.sup.33, R.sup.41, R.sup.42, R.sup.43, R.sup.5 and R.sup.
    Type: Grant
    Filed: June 1, 1987
    Date of Patent: September 4, 1990
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki
    Inventors: Masakazu Uekita, Hiroshi Awaji
  • Patent number: 4943471
    Abstract: A patterned thin film suitable for use in electric and electronic devices, prepared from a polymer or a mixture of the polymer and other known compounds capable of forming a thin film by LB technique, said polymer having linear recurring units wherein an organic group R.sup.1 having at least 2 carbon atoms and a valence of at least 2 is combined alternately with an organic group R.sup.2 having at least 2 carbon atoms and a valence of at least 2 through a bivalent group formed by a reaction of an acid group A containing a hetero atom and a basic group B containing a hetero atom, and wherein a hydrocarbon-containing group R.sup.3 having 10 to 30 carbon atoms which may contain a substituent group, is linked by covalent or ionic bond to said recurring units, the number of groups R.sup.3 being at least 2 per 10 recurring units.
    Type: Grant
    Filed: September 23, 1988
    Date of Patent: July 24, 1990
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masakazu Uekita, Hiroshi Awaji, Makoto Murata, Satoshi Mizunuma