Patents by Inventor Hiroshi Itaya

Hiroshi Itaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10538798
    Abstract: A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, as well as a method for secretory production of a heterologous protein. A coryneform bacterium is described that has been modified to have a specific mutation so as to harbor a phoS gene, and when cultured, is able to to produce a heterologous protein by secretory production.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: January 21, 2020
    Assignee: AJINOMOTO CO., INC.
    Inventors: Yoshihiko Matsuda, Yumi Ito, Yukari Kashima, Naoko Yamada, Noriko Tsurui, Hiroshi Itaya
  • Patent number: 10447017
    Abstract: An electric storage device includes an electric storage module, a bracket, an electric junction box, and a wire harness. The electric storage module includes electric storage components. The electric storage module includes an end surface and peripheral surfaces perpendicular to the end surface. The bracket is mounted to the electric storage module and includes a first surface opposed to the end surface of the electric storage module and a second surface opposite from the first surface. The electric junction box is mounted to the bracket to be opposed to the second surface of the bracket with a gap between the electric junction box and the second surface of the bracket. The wire harness is connected to the electric storage module and disposed in a section of the gap in which the end surface of the electric storage module is opposed to the electric junction box.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: October 15, 2019
    Assignees: AUTONETWORKS TECHNOLOGIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD., HONDA MOTOR CO., LTD.
    Inventors: Ryouya Okamoto, Hiroki Hirai, Tetsuji Tanaka, Hiroshi Shimizu, Hitoshi Takeda, Hiroki Itaya, Eiji Koike
  • Patent number: 10389174
    Abstract: A resource management system includes first and second opening/closing control mechanisms and a grid manager. The first and second control mechanisms each include: a controller to transmit a signal between a resource supply source and a load, a monitor to monitor a state of a resource from the source, a storage to store a policy defining the signal corresponding to the state of the resource from the source; and a path controller to generate the signal based on a monitoring result of the monitor and the policy. The grid manager includes: a third monitor to monitor the state of the resource from the first source; and a third path controller to generate at least one of the first and second signals by controlling at least one of the first path and second path controllers based on a monitoring result of the third monitor.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: August 20, 2019
    Assignee: NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY
    Inventors: Satoko Itaya, Fumihide Kojima, Hiroshi Harada
  • Publication number: 20190157851
    Abstract: An electric storage device includes an electric storage module, a bracket, an electric junction box, and a wire harness. The electric storage module includes electric storage components. The electric storage module includes an end surface and peripheral surfaces perpendicular to the end surface. The bracket is mounted to the electric storage module and includes a first surface opposed to the end surface of the electric storage module and a second surface opposite from the first surface. The electric junction box is mounted to the bracket to be opposed to the second surface of the bracket with a gap between the electric junction box and the second surface of the bracket. The wire harness is connected to the electric storage module and disposed in a section of the gap in which the end surface of the electric storage module is opposed to the electric junction box.
    Type: Application
    Filed: April 13, 2017
    Publication date: May 23, 2019
    Applicants: AUTONETWORKS TECHNOLOGIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD., HONDA MOTOR CO., LTD.
    Inventors: Ryouya OKAMOTO, Hiroki HIRAI, Tetsuji TANAKA, Hiroshi SHIMIZU, Hitoshi TAKEDA, Hiroki ITAYA, Eiji KOIKE
  • Publication number: 20180037918
    Abstract: A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, as well as a method for secretory production of a heterologous protein. A coryneform bacterium is described that has been modified to have a specific mutation so as to harbor a phoS gene, and when cultured, is able to to produce a heterologous protein by secretory production.
    Type: Application
    Filed: October 23, 2017
    Publication date: February 8, 2018
    Applicant: AJINOMOTO CO., INC.
    Inventors: Yoshihiko Matsuda, Yumi Ito, Yukari Kashima, Naoko Yamada, Noriko Tsurui, Hiroshi Itaya
  • Patent number: 9376701
    Abstract: A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, and thereby a method for secretory production of a heterologous protein is provided. A coryneform bacterium is cultured so that it secretes a heterologous protein, the bacterium having a genetic construct which includes a promoter sequence that functions in the coryneform bacterium, a nucleic acid sequence coding for a signal peptide that functions in the coryneform bacterium, which is ligated downstream from the promoter sequence, and a nucleic acid sequence coding for a fusion protein having an amino acid sequence that includes Gln-Glu-Thr and the heterologous protein, which is ligated downstream from the nucleic acid sequence coding for the signal peptide.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: June 28, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Noriko Tsurui, Hiroshi Itaya, Yoshimi Kikuchi
  • Patent number: 9187554
    Abstract: A method for secretory production of a heterologous protein is provided by developing a novel technique for improving ability of a coryneform bacterium to produce a heterologous protein by secretory production. By utilizing a coryneform bacterium having an ability to produce a heterologous protein by secretory production which has been modified so that the activity of a penicillin-binding protein is reduced and in which the activity of a cell surface layer protein has been reduced as an expression host, a heterologous protein is produced by secretory production.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: November 17, 2015
    Assignee: AJINOMOTO CO., INC.
    Inventors: Yoshihiko Matsuda, Hiroshi Itaya, Yoshimi Kikuchi, Haruki Beppu, Jurgis Antanas Vladovich Jomantas, Ekaterina Aleksandrovna Kutukova
  • Publication number: 20140255996
    Abstract: A method for secretory production of a heterologous protein is provided by developing a novel technique for improving ability of a coryneform bacterium to produce a heterologous protein by secretory production. By utilizing a coryneform bacterium having an ability to produce a heterologous protein by secretory production which has been modified so that the activity of a penicillin-binding protein is reduced and in which the activity of a cell surface layer protein has been reduced as an expression host, a heterologous protein is produced by secretory production.
    Type: Application
    Filed: April 29, 2014
    Publication date: September 11, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Yoshihiko Matsuda, Hiroshi Itaya, Yoshimi Kikuchi, Haruki Beppu, Jurgis Antanas Vladovich Jomantas, Ekaterina Aleksandrovna Kutukova
  • Publication number: 20140220637
    Abstract: A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, and thereby a method for secretory production of a heterologous protein is provided. A coryneform bacterium is cultured so that it secretes a heterologous protein, the bacterium having a genetic construct which includes a promoter sequence that functions in the coryneform bacterium, a nucleic acid sequence coding for a signal peptide that functions in the coryneform bacterium, which is ligated downstream from the promoter sequence, and a nucleic acid sequence coding for a fusion protein having an amino acid sequence that includes Gln-Glu-Thr and the heterologous protein, which is ligated downstream from the nucleic acid sequence coding for the signal peptide.
    Type: Application
    Filed: April 11, 2014
    Publication date: August 7, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Noriko Tsurui, Hiroshi Itaya, Yoshimi Kikuchi
  • Patent number: 8597907
    Abstract: The present invention provides a method for efficiently producing an industrially useful protein in coryneform bacteria, and more particularly, a method for efficiently producing a protein for which secretion was difficult using conventional protein secretion pathways. In particular, the present invention provides a method for efficiently producing heterologous proteins comprising culturing coryneform bacteria containing an genetic construction containing a promoter sequence which functions in coryneform bacteria, a nucleic acid sequence encoding a Tat system-dependent signal peptide region, and a nucleic acid sequence encoding a heterologous protein, in the direction from 5?-end to 3?-end, and secretory producing the heterologous protein by coryneform bacteria.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: December 3, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masayo Date, Yoshimi Kikuchi, Hiroshi Itaya, Nami Nakamura
  • Patent number: 8187835
    Abstract: By culturing a methanol-assimilating bacterium which harbors a DNA construct which contains a promoter sequence that functions in the methanol-assimilating bacterium and a nucleotide sequence that encodes a polypeptide containing a signal sequence and an objective protein which is functionally connected to the promoter sequence, in a liquid medium containing methanol as a major carbon source, the bacterium is allowed to secrete the objective protein, and the secreted objective protein is recovered.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: May 29, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Hiroshi Itaya, Yoshimi Kikuchi, Masayo Date
  • Publication number: 20090130534
    Abstract: In order to attain excellent electrical conductivity and molding processability, a fuel cell separator to be produced by performing press molding on a preform in which expanded graphite is used as the main raw material is improved so that the preform is produced by a papermaking method, whereby the characteristics of the mechanical strength, the flexibility, and the gas impermeability are improved, and the moldability is made excellent so that a light and compact configuration that is preferred in the automobile use or the like can be realized.
    Type: Application
    Filed: April 13, 2007
    Publication date: May 21, 2009
    Applicant: Nippon Pillar Packing Co., Ltd,
    Inventors: Kazuhiko Otawa, Akira Hashimoto, Nobuhiko Ikeda, Kenichi Horiki, Toshimitsu Tanii, Hiromi Konishi, Hiroshi Itaya
  • Publication number: 20080160575
    Abstract: By culturing a methanol-assimilating bacterium which harbors a DNA construct which contains a promoter sequence that functions in the methanol-assimilating bacterium and a nucleotide sequence that encodes a polypeptide containing a signal sequence and an objective protein which is functionally connected to the promoter sequence, in a liquid medium containing methanol as a major carbon source, the bacterium is allowed to secrete the objective protein, and the secreted objective protein is recovered.
    Type: Application
    Filed: November 13, 2007
    Publication date: July 3, 2008
    Applicant: Ajinomoto Co. Inc.
    Inventors: Hiroshi ITAYA, Yoshimi Kikuchi, Masayo Date
  • Publication number: 20070184525
    Abstract: The present invention provides a method for efficiently producing an industrially useful protein in coryneform bacteria, and more particularly, a method for efficiently producing a protein for which secretion was difficult using conventional protein secretion pathways. In particular, the present invention provides a method for efficiently producing heterologous proteins comprising culturing coryneform bacteria containing an genetic construction containing a promoter sequence which functions in coryneform bacteria, a nucleic acid sequence encoding a Tat system-dependent signal peptide region, and a nucleic acid sequence encoding a heterologous protein, in the direction from 5?-end to 3?-end, and secretory producing the heterologous protein by coryneform bacteria.
    Type: Application
    Filed: October 19, 2006
    Publication date: August 9, 2007
    Inventors: Masayo Date, Yoshimi Kikuchi, Hiroshi Itaya, Nami Nakamura
  • Publication number: 20050193862
    Abstract: A method for manufacturing sponge iron and an apparatus for charging in the method are disclosed. Iron oxide powder and reducing-agent powder are charged such that alternating layers of the iron oxide powder and the reducing-agent powder are formed and such that each of the layers is in the form of a helix, and then a reduction treatment is performed. The method has not only high reaction efficiency of a gas, high quality, and high productivity, but also the advantage for a production adjustment because the amount of charge can be adjusted without the limitation of a reduction time. The molar ratio of the carbon content in the reducing agent to the oxygen content in the iron oxide in the reaction container is preferably 1.1 or more.
    Type: Application
    Filed: January 29, 2004
    Publication date: September 8, 2005
    Applicant: JFE STEEL CORPORATION
    Inventors: Yoshitomo Suzuki, Akio Sonobe, Takashi Kuroki, Yasuhiko Sakaguchi, Hiroshi Itaya, Yotsuo Misumi, Isao Funatsu
  • Patent number: 6801996
    Abstract: An instruction code conversion unit, an information processing system provided with the instruction code conversion unit and an instruction code generation method for generating instruction codes which are converted by the instruction code conversion unit are described. The efficiency of coding of the program is improved by making use of an existing processor as selected is used without modification. An instruction code conversion unit performs conversion of the address of a native instruction code to the address of the corresponding compressed instruction code in a program memory by shifting the address of the native instruction code as outputted from the processor to the right by one bit.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: October 5, 2004
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Moriyasu Banno, Tomoaki Shoda, Hiroshi Itaya, Tomotaka Saito
  • Publication number: 20010013093
    Abstract: An instruction code conversion unit, an information processing system provided with the instruction code conversion unit and an instruction code generation method for generating instruction codes which are converted by the instruction code conversion unit are described. The efficiency of coding of the program is improved by making use of an existing processor as selected is used without modification. An instruction code conversion unit performs conversion of the address of a native instruction code to the address of the corresponding compressed instruction code in a program memory by shifting the address of the native instruction code as outputted from the processor to the right by one bit.
    Type: Application
    Filed: February 7, 2001
    Publication date: August 9, 2001
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Moriyasu Banno, Tomoaki Shoda, Hiroshi Itaya, Tomotaka Saito
  • Patent number: 6224820
    Abstract: A traveling hearth for producing reduced metal by charging and stacking a raw material containing a metal-containing material and a solid-reducing material on a horizontally moving hearth, arranged for disposing a solid-reducing material layer on the hearth, forming concave portions at the solid-reducing material surface, stacking the raw material on the surface of the solid-reducing material layer, reducing the raw material by at least once heating and melting the material on the hearth to separate metal and gangue and ash ingredients, and discharging metal from the hearth.
    Type: Grant
    Filed: October 5, 1999
    Date of Patent: May 1, 2001
    Assignee: Kawasaki Steel Corporation
    Inventors: Yoshitaka Sawa, Tetsuya Yamamoto, Kanji Takeda, Hiroshi Itaya
  • Patent number: 6126718
    Abstract: Producing reduced metal by charging and stacking a raw material containing a metal-containing material and a solid reducing material on a horizontally moving hearth of a traveling hearth furnace, by disposing a solid reducing material layer on the hearth, forming concave portions at the solid reducing material surface, stacking the raw material on the surface of the solid reducing material layer, reducing raw material by at least once heating and melting the material on the hearth to separate metal and gangue and ash ingredients, and discharging metal from the hearth.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: October 3, 2000
    Assignee: Kawasaki Steel Corporation
    Inventors: Yoshitaka Sawa, Tetsuya Yamamoto, Kanji Takeda, Hiroshi Itaya
  • Patent number: 5766307
    Abstract: Method and apparatus for collecting valuable products, particularly zinc, from a zinc-containing substance such as electric furnace dust. A shaft type smelting reduction furnace has a packed bed of a carbonaceous solid reducing agent and has upper and lower tuyeres, and a zinc-containing substance is injected through tuyeres to reduce and vaporize zinc, which is directly contacted by a liquid coolant thereby forming a slurry, and the zinc product is collected from the slurry.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: June 16, 1998
    Assignee: Kawasaki Steel Corporation
    Inventors: Shoji Miyagawa, Hiroshi Itaya, Tetsuya Fujii, Yoshiaki Hara