Patents by Inventor Hiroshi Murai

Hiroshi Murai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240277861
    Abstract: An anti-HBV agent according to the present invention contains as an active ingredient a substance that binds to LIPG and inhibits the function(s) of LIPG. The inventors of the present application have found that LIPG is a factor playing an important role in HBV attachment and uptake, and functions as a cofactor that supports HBV entry into cells independently of NTCP, and also contributes to HBV proliferation in cells. T The LIPG-binding substance binds to LIPG on the surface of liver cells to inhibit HBV attachment and uptake into cells and, when delivered into liver cells, binds to intracellular LIPG to block any step(s) in the intracellular HBV proliferation process, thereby exerting an anti-HBV activity.
    Type: Application
    Filed: July 22, 2022
    Publication date: August 22, 2024
    Applicant: PUROTECH BIO, INC.
    Inventors: Hiroshi YANAGAWA, Noriko TABATA, Yuko YONEMURA, Mayuko IDE, Satoru ITO, Shuichi KANEKO, Masao HONDA, Takayoshi SHIRASAKI, Kazuhisa MURAI, Hikari OKADA
  • Patent number: 11939879
    Abstract: This blade repair method has: a first welding step in which overlay welding in which a first welding material is used is performed to form a notched part and a bury a first region positioned on a blade-body side with a first welding material; and a second welding step in which, after the first welding step, overlay welding in which a second welding material is used is performed to form a notched part and bury a second region positioned on a front-surface side of a platform with the second welding material. The high-temperature strength of the second welding material is higher than the high-temperature strength of the first welding material, the weldability of the first welding material is higher than the weldability of the second welding material, and the second region is located in a range from 1.0 mm to 3.0 mm (inclusive) from the front surface of the platform toward the blade body.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: March 26, 2024
    Assignee: MITSUBISHI HEAVY INDUSTRIES, LTD.
    Inventors: Osamu Ueda, Hiroshi Murai, Ryoji Fushino
  • Publication number: 20230025087
    Abstract: This blade repair method has: a first welding step in which overlay welding in which a first welding material is used is performed to form a notched part and a bury a first region positioned on a blade-body side with a first welding material; and a second welding step in which, after the first welding step, overlay welding in which a second welding material is used is performed to form a notched part and bury a second region positioned on a front-surface side of a platform with the second welding material. The high-temperature strength of the second welding material is higher than the high-temperature strength of the first welding material, the weldability of the first welding material is higher than the weldability of the second welding material, and the second region is located in a range from 1.0 mm to 3.0 mm (inclusive) from the front surface of the platform toward the blade body.
    Type: Application
    Filed: December 17, 2020
    Publication date: January 26, 2023
    Inventors: Osamu UEDA, Hiroshi MURAI, Ryoji FUSHINO
  • Publication number: 20210001739
    Abstract: A charge/discharge device includes: a first component to be used for power conversion; a second component to be used for power conversion, the second component generating a smaller amount of heat than the first component during operation, the second component having a lower allowable temperature than the first component; a housing to house the first component and the second component; and an internal circulation fan to circulate air inside the housing. The first component is placed below the second component. The internal circulation fan is placed above the first component and blows air to the first component.
    Type: Application
    Filed: February 22, 2019
    Publication date: January 7, 2021
    Applicant: Mitsubishi Electric Corporation
    Inventors: Hideyuki MURAI, Tomomi MATSUI, Hiroshi MURAI
  • Publication number: 20160272488
    Abstract: The present invention relates to a through electrode to be mounted on a substrate having a through hole. The through electrode includes: a penetrating part that passes through the through hole; a convex bump part that is formed on at least one end of the penetrating part and is wider than the through electrode; and a metal film that has at least one layer and is formed on a surface of the convex bump part that comes in contact with the substrate. The through electrode part and the convex bump part are formed of a sintered body prepared by sintering one or more kind of metal powder selected from gold, silver, palladium, and platinum having a purity of 99.9 wt % or more and an average particle size of 0.005 ?m to 1.0 ?m, and the metal film contains gold, silver, palladium, or platinum having a purity of 99.9 wt % or more.
    Type: Application
    Filed: November 10, 2014
    Publication date: September 22, 2016
    Inventors: Toshinori OGASHIWA, Hiroshi MURAI, Yukio KANEHIRA
  • Publication number: 20120007900
    Abstract: A control drive circuit provided in an FSC-LCD comprises an input stage signal processing/controlling circuit (21) which generates a synchronization signal (32) in synchronization with a frame frequency of an input image signal (30) and image data (34); a sequencer (22) which determines the number of color fields in one frame, a color signal to be allocated to each color field, and the output sequence of the allocated color signals and which generates and outputs field designation signals (38, 40) used to designate the color fields corresponding to the output sequence; and an output stage signal processing/controlling circuit (25) which receives image data (36) from the input stage signal processing/controlling circuit (21) and outputs signals to a source driver (13) and a gate driver (14), in accordance with the field designation signal (38) from the sequencer (22).
    Type: Application
    Filed: March 2, 2010
    Publication date: January 12, 2012
    Applicant: AMORI SUPPORT CENTER FOR INDUSTRIAL PROMOTION
    Inventors: Hiroshi Murai, Kazuo Sekiya, Kazuhiro Wako
  • Patent number: 7910980
    Abstract: The present invention provides a semiconductor device and a method for manufacturing thereof. The semiconductor device includes bit lines disposed in a semiconductor substrate, a first ONO disposed between the bit lines on the semiconductor substrate, and a second ONO film disposed on each of the bit lines. The film thickness of a first silicon nitride film in the first ONO film is larger than the film thickness of a second silicon nitride film in the second ONO film.
    Type: Grant
    Filed: September 22, 2008
    Date of Patent: March 22, 2011
    Assignee: Spansion LLC
    Inventors: Hiroshi Murai, Masahiko Higashi
  • Publication number: 20110058979
    Abstract: [Issues to be Solved] Second bonding failures caused by attached oxide of additive elements on high purity Au bonding wire are to be resolved. [Solution Means] Au alloy bonding wires comprising: 5-100 wt ppm Mg, 5-20 wt ppm In, 5-20 wt ppm Al, 5-20 wt ppm Yb, and residual Au of 99.995 wt % purity or higher, and adding 5-20 wt ppm Ca, and for these alloys adding at least one element among 5-20 wt ppm La, 5-20 wt ppm Lu, 5-100 wt ppm Sn, 5-100 wt ppm Sr to the alloy, and/or, moreover, adding 0.01-1.2 wt % Pd to these alloys. Bonding wire, which contains these trace additive elements do not cause a disturbance by accumulated contamination, because of contamination, which formed at ball formation by micro discharge and at the first bonding on the tip of the capillary, transferring to the wire at second bonding.
    Type: Application
    Filed: September 11, 2008
    Publication date: March 10, 2011
    Applicant: TANAKA DENSHI KOGYO K. K.
    Inventors: Hiroshi Murai, Jun Chiba, Fujio Amada
  • Patent number: 7825448
    Abstract: A semiconductor device and a method for manufacturing thereof are provided. The semiconductor device includes two epitaxial semiconductor layers formed on a semiconductor substrate, bit lines formed on upper portions of the two epitaxial semiconductor layers, and a charge storage layer formed on the semiconductor substrate between the two epitaxial semiconductor layers.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: November 2, 2010
    Assignee: Spansion LLC
    Inventors: Masatomi Okanishi, Yoshihiro Mikasa, Hiroshi Murai
  • Publication number: 20100171222
    Abstract: [Issues to be Solved] Providing enhanced bonding reliability of Au alloy bonding wire with low electrical resistivity to Al electrode of semiconductor device, and its application of semiconductor device is bonded with Al electrode pad by the same wire. [Solution Means] Au alloy bonding wire comprising: 0.02-0.3 mass % Ag, total amount of 10-200 mass ppm at least one element of Ge and/or Si, and/or total amount of 10-200 mass ppm at least one element of Al and/or Cu, with residual of Au. Moreover, Al and/or Al alloy pad bonded with the above Au alloy bonding wire.
    Type: Application
    Filed: March 26, 2008
    Publication date: July 8, 2010
    Applicant: TANAKA DENSHI KOGYO K.K.
    Inventors: Hiroshi Murai, Jun Chiba, Fujio Amada
  • Patent number: 7736953
    Abstract: A semiconductor memory includes first and second source regions that are formed in a semiconductor substrate and run in orthogonal directions. The first and second source regions are diffused regions and are electrically connected to each other at crossing portions thereof. The semiconductor device may further include drain regions formed in the semiconductor substrate, bit lines that run in the direction in which the second source region runs, and a source line formed above the second source region, wherein a contact between the source line and the second source region is aligned with contacts between the bit lines and drain regions formed in the semiconductor substrate.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: June 15, 2010
    Assignee: Spansion LLC
    Inventors: Hiroshi Murai, Masahiko Higashi
  • Patent number: 7645693
    Abstract: A semiconductor device includes bit lines (14) provided in a semiconductor substrate (10), word lines (16) provided above the bit lines and running in a width direction of the bit lines (14), metal lines (22) provided above the word lines (16) and running in a length direction of the bit lines (14), and bit line contact regions (28) running in the length direction of the word lines (16) and located between word line regions (26) in which a plurality of word lines (16) are disposed. Each of the bit lines (14) is connected with every other metal line (22) in the bit line contact regions (28). It is thus possible to provide a semiconductor device and a fabrication method therefor in which an alignment margin can be ensured between a contact hole (18) and the bit line (14) to enable downsizing of a memory cell.
    Type: Grant
    Filed: April 27, 2006
    Date of Patent: January 12, 2010
    Assignee: Spansion LLC
    Inventor: Hiroshi Murai
  • Publication number: 20090237990
    Abstract: The present invention provides a semiconductor device and a method for manufacturing thereof. The semiconductor device includes bit lines disposed in a semiconductor substrate, a first ONO disposed between the bit lines on the semiconductor substrate, and a second ONO film disposed on each of the bit lines. The film thickness of a first silicon nitride film in the first ONO film is larger than the film thickness of a second silicon nitride film in the second ONO film.
    Type: Application
    Filed: September 22, 2008
    Publication date: September 24, 2009
    Inventors: Hiroshi MURAI, Masahiko Higashi
  • Publication number: 20090200599
    Abstract: A semiconductor device and a method for manufacturing thereof are provided. The semiconductor device includes two epitaxial semiconductor layers formed on a semiconductor substrate, bit lines formed on upper portions of the two epitaxial semiconductor layers, and a charge storage layer formed on the semiconductor substrate between the two epitaxial semiconductor layers.
    Type: Application
    Filed: August 15, 2008
    Publication date: August 13, 2009
    Inventors: Masatomi OKANISHI, Yoshihiro MIKASA, Hiroshi Murai
  • Publication number: 20080050267
    Abstract: Provided is a thin Au alloy bonding wire having desired strength, good bondability and stability over time, and improved circularity of a squashed ball and sphericity of a melted ball. The Au alloy bonding wire contains, in an Au alloy matrix containing 0.05 to 2 mass % in total of at least one selected from Pd and Pt of high purity in Au of high purity, as trace elements, 10 to 100 ppm by mass of Mg, 5 to 100 ppm by mass of Ce, and 5 to 100 ppm by mass of each of at least one selected from Be, Y, Gd, La, Eu and Si, the total content of Be, Y, Gd, La, Eu and Si being 5 to 100 ppm by mass, or as trace elements, Mg, Be, and at least one selected from Y, La, Eu and Si, or as trace elements, 10 to 100 ppm by mass of Mg, 5 to 30 ppm by mass of Si, 5 to 30 ppm by mass of Be, and 5 to 30 ppm by mass of at least one selected from Ca, Ce and Sn.
    Type: Application
    Filed: September 28, 2005
    Publication date: February 28, 2008
    Inventors: Hiroshi Murai, Jun Chiba, Satoshi Teshima
  • Publication number: 20070054454
    Abstract: A semiconductor device includes bit line's (14) provided in a semiconductor substrate (10), word lines (16) provided above the bit lines and running in a width direction of the bit lines (14), metal lines (22) provided above the word lines (16) and running in a length direction of the bit lines (14), and bit line contact regions (28) running in the length direction of the word lines (16) and located between word line regions (26) in which a plurality of word lines (16) are disposed. Each of the bit lines (14) is connected with every other metal line (22) in the bit line contact regions (28). It is thus possible to provide a semiconductor device and a fabrication method therefor in which an alignment margin can be ensured between a contact hole (18) and the bit line (14) to enable downsizing of a memory cell.
    Type: Application
    Filed: April 27, 2006
    Publication date: March 8, 2007
    Inventor: Hiroshi Murai
  • Publication number: 20060246314
    Abstract: A material for a semiconductor-mounting heat dissipation substrate comprises a copper-molybdenum rolled composite obtained by impregnating melted copper into a void between powder particles of a molybdenum powder compact to obtain a molybdenum-copper composite and then rolling the composite. In a final rolling direction of a plate material, the coefficient of linear expansion is 8.3×10?6/K at 30-800° C. The material for a semiconductor-mounting heat dissipation substrate is superior in thermal conductivity to a CMC clad material and easy in machining by a punch press. The substrate material is used as a heat dissipation substrate (13) of a ceramic package (11).
    Type: Application
    Filed: June 23, 2006
    Publication date: November 2, 2006
    Inventors: Mitsuo Osada, Norio Hirayama, Tadashi Arikawa, Yoshinari Amano, Hidetoshi Maesato, Hidefumi Hayashi, Hiroshi Murai
  • Patent number: 7083759
    Abstract: A material for a semiconductor-mounting heat dissipation substrate comprises a copper-molybdenum rolled composite obtained by impregnating melted copper into a void between powder particles of a molybdenum powder compact to obtain a composite of molybdenum and copper and then rolling the composite. In a final rolling direction of a plate material, the coefficient of linear expansion is 8.3×10?6/K at 30–800° C. The material for a semiconductor-mounting heat dissipation substrate is superior in thermal conductivity to a CMC clad material and easy in machining by a punch press. The substrate material is used as a heat dissipation substrate (13) of a ceramic package (11).
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: August 1, 2006
    Assignee: A.L.M.T. Corp.
    Inventors: Mitsuo Osada, Norio Hirayama, Tadashi Arikawa, Yoshinari Amano, Hidetoshi Maesato, Hidefumi Hayashi, Hiroshi Murai
  • Publication number: 20060091422
    Abstract: A semiconductor memory includes first and second source regions that are formed in a semiconductor substrate and run in orthogonal directions. The first and second source regions are diffused regions and are electrically connected to each other at crossing portions thereof. The semiconductor device may further include drain regions formed in the semiconductor substrate, bit lines that run in the direction in which the second source region runs, and a source line formed above the second source region, wherein a contact between the source line and the second source region is aligned with contacts between the bit lines and drain regions formed in the semiconductor substrate.
    Type: Application
    Filed: November 30, 2005
    Publication date: May 4, 2006
    Inventors: Hiroshi Murai, Masahiko Higashi
  • Publication number: 20020191377
    Abstract: A material for a semiconductor-mounting heat dissipation substrate comprises a copper-molybdenum rolled composite obtained by impregnating melted copper into a void between powder particles of a molybdenum powder compact to obtain a composite of molybdenum and copper and then rolling the composite. In a final rolling direction of a plate material, the coefficient of linear expansion is 8.3×10−6/K at 30-800° C. The material for a semiconductor-mounting heat dissipation substrate is superior in thermal conductivity to a CMC clad material and easy in machining by a punch press. The substrate material is used as a heat dissipation substrate (13) of a ceramic package (11).
    Type: Application
    Filed: December 13, 2001
    Publication date: December 19, 2002
    Inventors: Mitsuo Osada, Norio Hirayama, Tadashi Arikawa, Yoshinaro Amano, Hidetoshi Maesato, Hidefumi Hayashi, Hiroshi Murai