Abstract: A flaw detection image analyzer (10) takes in an inspection procedure command stored in a flaw detection condition database (40), takes in a flaw detection image signal corresponding to a flaw detection image indicated by the taken inspection procedure command from a database (50) for flaw detection image signal, and displays the flaw detection image based on the flaw detection image signal on a display (30), with a display range and a contrast indicated by the inspection procedure command in an arrangement pattern of image indicated by the inspection procedure command. Consequently, optimum images can be displayed sequentially with optimum arrangement pattern, optimum display range and contrast according to a flaw to be inspected when a flaw is detected by observing an ultrasonic flaw detection image.

Abstract: A flaw detection image analyzer (10) takes in an inspection procedure command stored in a flaw detection condition database (40), takes in a flaw detection image signal corresponding to a flaw detection image indicated by the taken inspection procedure command from a database (50) for flaw detection image signal, and displays the flaw detection image based on the flaw detection image signal on a display (30), with a display range and a contrast indicated by the inspection procedure command in an arrangement pattern of image indicated by the inspection procedure command. Consequently, optimum images can be displayed sequentially with optimum arrangement pattern, optimum display range and contrast according to a flaw to be inspected when a flaw is detected by observing an ultrasonic flaw detection image.

Abstract: The problem of the present invention is to prove a medicament for decreasing body weigh, a medicament for decreasing visceral fat, a medicament for decreasing triglyceride in the liver, and a method for screening a medicament for ameliorating obesity and fatty liver. The problem is solved by a method comprising measuring an activity of a candidate material for inhibiting a sphingomyelin synthetase wherein if the candidate material has an activity for inhibiting a sphingomyelin synthetase, the candidate material is judged to have at least one function selected from the consisting of an anti-obesity drug, a drug for decreasing visceral fat, a drug for treating fatty liver and an agent for increasing adiponectin expression.

Abstract: An EGR cooling structure is provided. The EGR cooling structure (1) comprising: a cylinder block (11) having cylinders (11a); a cylinder head (12) (exhaust gas manifold section) into which exhaust gas exhausted from the cylinders (11a) is collected; an exhaust emission control device (20) for purifying the exhaust gas exhausted from the cylinder head (12); an EGR pipe (50) through which EGR gas of a part of the purified exhaust gas is introduced into an intake system r intake system from second exhaust gas piping (32) downstream of the exhaust gas purification device (20); and an EGR cooler (60) provided in the EGR pipe (50) and cooling the EGR gas with the cooling liquid. An exhaust gas passage leading from the cylinders (11a) to the exhaust gas purification device (20) is curved when seen from a side, and the EGR cooler (60) is disposed in the space (5) surrounded by the cylinder block (11), the cylinder head (12), and the exhaust gas purification device (20).

Abstract: A disclosed image pickup apparatus includes a first member holding a lens, and a second member holding an image pickup element converting an image formed via the lens into an electric signal, the second member having an approximately rectangular shape and two approximately arc-shaped location cutout portions at respective diagonal corners of the approximately rectangular shape. In the image pickup apparatus, the first and the second members are bonded via an indirect bonding structure portion where the first and second members are bonded via a fixing member with an ultraviolet curable adhesive and a filler bonding structure portion where the first and second members are bonded by supplying a thermosetting adhesive therebetween.

Abstract: An optical scanning device configured to irradiate an object with light generating from a light source via at least one mirror with a first end portion and second end portion which are attached to a housing and to scan the object with the irradiating light is provided, wherein the first end portion of the at least one mirror is movably supported by the housing and the second end portion of the at least one mirror is bonded to the housing.

Abstract: Disclosed is a method for screening for a medicinal agent that can decrease a body weight, a medicinal agent that can reduce a visceral fat, a medicinal agent that can reduce a triglyceride in the liver, and a medicinal agent that can ameliorate obesity and fatty liver. The method involves a step of measuring the inhibitory activity of a candidate substance on a sphingomyelin synthase, wherein the candidate substance is determined to have at least one function selected from the group consisting of an anti-obesity agent, a visceral fat-reducing agent, a fatty liver-treating agent and an adiponectin expression enhancer when the candidate substance has an inhibitory activity on the sphingomyelin synthase.

Abstract: A mirror includes a substrate, a reflection layer, and a protection layer. The substrate includes a surface having an attachment area and a reflection area. The reflection layer is formed on the reflection area. The protection layer is formed on the reflection area on which the reflection layer is formed and the attachment area. Material of the protection layer is homogeneous across the reflection area and the attachment area.

Abstract: A flaw detection image analyzer (10) takes in an inspection procedure command stored in a flaw detection condition database (40), takes in a flaw detection image signal corresponding to a flaw detection image indicated by the taken inspection procedure command from a database (50) for flaw detection image signal, and displays the flaw detection image based on the flaw detection image signal on a display (30), with a display range and a contrast indicated by the inspection procedure command in an arrangement pattern of image indicated by the inspection procedure command. Consequently, optimum images can be displayed sequentially with optimum arrangement pattern, optimum display range and contrast according to a flaw to be inspected when a flaw is detected by observing an ultrasonic flaw detection image.

Abstract: An image-capturing device including: an imaging optical system which is configured to capture an optical image of a subject; an imaging optical system retaining member which retains the imaging optical system; an imaging element which is configured to convert the optical image into an electrical signal; a substrate which is arranged on a back side of the imaging optical system retaining member and retains the imaging element; and a plurality of substrate joint pieces each of which extends from the imaging optical system retaining member toward the substrate, wherein tip parts of the plurality of substrate joint pieces on a substrate side and the substrate are joined by an indirect bond structure using at least one joint intermediate member which is adhered to at least one of the tip parts of the plurality of substrate joint pieces and the substrate with an adhesive, and a fixation structure.

Abstract: A base tube for an electrophotographic photoconductive member, is provided with a cylindrical body on which a photoconductive layer is formed; and a first slanting portion formed on a peripheral surface of an end portion of the cylindrical body, and slanting inward toward an end face of the end portion with respect to an axis of the cylindrical body. An axial length of the first slanting portion of the cylindrical body is within a range of 0.3 to 5 mm.

Abstract: A disclosed image pickup apparatus includes a first member holding a lens, and a second member holding an image pickup element converting an image formed via the lens into an electric signal, the second member having an approximately rectangular shape and two approximately arc-shaped location cutout portions at respective diagonal corners of the approximately rectangular shape. In the image pickup apparatus, the first and the second members are bonded via an indirect bonding structure portion where the first and second members are bonded via a fixing member with an ultraviolet curable adhesive and a filler bonding structure portion where the first and second members are bonded by supplying a thermosetting adhesive therebetween.

Abstract: Pharmaceutical compositions containing as an active ingredient compounds of the general formula (I), prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them and exhibiting thrombopoietin receptor agonism: X1—Y1-Z1-W1??(I) wherein X1 is optionally substituted aryl, optionally substituted heteroaryl or the like; Y1 is —NRACO—(CH2)0-2— or the like (wherein RA is a hydrogen or the like); Z1 is optionally substituted phenylene or the like; and W1 is a group represented by the below formula: wherein R1, R2, R3, and R4 are each independently a hydrogen atom, optionally substituted lower alkyl or the like, a broken line (---) represents the presence or absence of bond.

Abstract: The present invention is intended to provide a method of rapidly, simply and accurately measuring a recombinant protein. As means for resolution, the protein quantity is measured by causing the expression of a fusion protein with the target protein and epitope tags containing two types of epitopes, bringing them into contact with detection antibodies which specifically recognize each epitope, and detecting a phenomenon caused by both detection antibodies coming close to each other.

Abstract: Pharmaceutical compositions containing as an active ingredient compounds of the general formula (I), prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them and exhibiting thrombopoietin receptor agonism: X1—Y1-Z1-W1??(I) wherein X1 is optionally substituted aryl, optionally substituted heteroaryl or the like; Y1 is —NRACO—(CH2)0-2— or the like (wherein RA is a hydrogen or the like); Z1 is optionally substituted phenylene or the like; and W1 is a group represeted by the below formula: wherein R1, R2, R3, and R4 are each independently a hydrogen atom, optionally substituted lower alkyl or the like, a broken line ( - - - ) represents the presence or absence of bond.

Abstract: A mirror includes a substrate, a reflection layer, and a protection layer. The substrate includes a surface having an attachment area and a reflection area. The reflection layer is formed on the reflection area. The protection layer is formed on the reflection area on which the reflection layer is formed and the attachment area. Material of the protection layer is homogeneous across the reflection area and the attachment area.

Abstract: The invention provides a more highly accurate assay for measuring the transcriptional activity of a test substance. Disclosed is a reporter gene assay, comprising the steps of contacting a cell having a vector wherein a reporter gene containing a gene encoding an epitope tag is ligated downstream to a recognition sequence of a transcription factor and a nucleotide sequence necessary for transcriptional initiation, with a test substance and detection antibodies; detecting a phenomenon caused by the two kinds of detection antibodies coming close to each other; and correlating the detected phenomenon with the effect of the test substance on transcriptional regulatory mechanism.

Abstract: A method and an apparatus for fixing a part and a part support for mounting the part by use of adhesive via an intermediate member are disclosed. The adhesive is implemented by photocuring adhesive while the intermediate member is formed of a material transparent for light. The intermediate member is free from coloring and deformation when illuminated by light for curing the adhesive. The adhesive is prevented from dropping or turning round to other portions during assembly.

Abstract: An optical scanning device configured to irradiate an object with light generating from a light source via at least one mirror with a first end portion and second end portion which are attached to a housing and to scan the object with the irradiating light is provided, wherein the first end portion of the at least one mirror is movably supported by the housing and the second end portion of the at least one mirror is bonded to the housing.

Abstract: There is disclosed a test apparatus including a driver that outputs a test signal, a first switch that is provided between the driver and a terminal of the first device under test, a second switch that is provided between the driver and a terminal of the second device under test, a first termination resistor that terminates the output signal from the driver in the terminal of the first device under test, a second termination resistor that terminates the output signal from the driver in the terminal of the second device under test, and a substitute resistor that is decoupled from the driver when the driver is connected to the terminals of the first and second device under test, and is connected to the driver when the driver and the terminal of the second device under test are disconnected.