Patents by Inventor Hiroshi Tomoda

Hiroshi Tomoda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9896456
    Abstract: This invention provides a novel non-natural pharmaceutical compound having a different mechanism than statin drugs and having a selective inhibitory activity against ACAT2.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: February 20, 2018
    Assignee: School Juridical Person Kitasato Institute
    Inventors: Hiroshi Tomoda, Masaki Ohtawa, Satoshi Omura, Tohru Nagamitsu
  • Publication number: 20170204114
    Abstract: This invention provides a novel non-natural pharmaceutical compound having a different mechanism than statin drugs and having a selective inhibitory activity against ACAT2.
    Type: Application
    Filed: June 18, 2015
    Publication date: July 20, 2017
    Applicant: School Juridical Person Kitasato Institute
    Inventors: Hiroshi Tomoda, Masaki Ohtawa, Satoshi Omura, Tohru Nagamitsu
  • Publication number: 20170010005
    Abstract: A heating cooking device includes a casing accommodating a heating furnace allowing a heating target to be located therein; a water storage tank; a hot vapor generation device connected with the water storage tank; a superheated vapor generation device heating hot vapor; a fan introducing superheated vapor into the heating furnace; and a superheated vapor discharge portion. The hot vapor generation device includes a first electric heater; and a first housing accommodating the first electric heater. A water level in the first housing matches a water level in the water storage tank. The superheated vapor generation device includes a second electric heater; and a second housing accommodating the second electric heater. At least a part of the second housing is located in an interior of the heating furnace. The hot vapor generation and the superheated vapor generation device are accommodated in the casing.
    Type: Application
    Filed: July 7, 2016
    Publication date: January 12, 2017
    Applicant: Tomoda Selling & Sailing Co., Ltd.
    Inventor: Hiroshi TOMODA
  • Publication number: 20150335190
    Abstract: A retort sterilization device includes a water steam generation device for generating water steam and a heating pot, connected to the water steam generation device, for accommodating retort food. The water steam generation device includes a heat exchanger for performing heat exchange between liquid flowing in a liquid path and heating vapor flowing in the vapor path. A top end of the liquid path of the heat exchanger is connected via a water steam supply pipe to a water steam ejection section located in an internal area of the heating pot. The heat exchanger is connected to a liquid container. A bottom end of the liquid path of the heat exchanger is connected to the liquid container via a communicating tube. The liquid container is coupled to the heating pot.
    Type: Application
    Filed: July 28, 2015
    Publication date: November 26, 2015
    Inventors: Hiroshi TOMODA, Norio KADOWAKI, Hironobu TOMODA, Manabu MORIWAKI, Satoru KADOWAKI
  • Patent number: 9187492
    Abstract: A compound effective in prevention and treatment of arteriosclerosis with a mechanism different from that of statin drugs has the following formula or a pharmaceutically acceptable salt, solvate, or hydrate thereof: wherein R1 is an aliphatic, alicyclic, or aromatic acyloxy group, or a group of the formula —O—CH(R7)—R8 where R7 is a lower alkoxy group and R8 is an aryl group, and R2 is carboxyl, a lower alkoxycarbonyl group, or an arylmethylcarbamoyl group, or a —CH2-acyloxy group and R3 is an aliphatic, alicyclic or aromatic acyloxy group, provided that at least one of R4 and R3 is a group other than acetoxy, or R2 and R3 taken together form a group of the formula —O—CH(R5)—O— where R5 is an aryl group.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: November 17, 2015
    Assignee: School Juridical Person Kitasato Institute
    Inventors: Hiroshi Tomoda, Tohru Nagamitsu, Daisuke Matsuda, Taichi Ohshiro, Masaki Ohtawa, Satoshi Omura
  • Patent number: 9125428
    Abstract: A retort sterilization device includes a water steam generation device for generating water steam and a heating pot, connected to the water steam generation device, for accommodating retort food. The water steam generation device includes a heat exchanger for performing heat exchange between liquid flowing in a liquid path and heating vapor flowing in the vapor path. A top end of the liquid path of the heat exchanger is connected via a water steam supply pipe to a water steam ejection section located in an internal area of the heating pot. The heat exchanger is connected to a liquid container. A bottom end of the liquid path of the heat exchanger is connected to the liquid container via a communicating tube. The liquid container is coupled to the heating pot.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: September 8, 2015
    Assignees: Tomoda Selling & Sailing Co., Ltd., Tomoda Fisheries Co., Ltd., Houshou Co., Ltd., Wakisangyou Yugenkaisha
    Inventors: Hiroshi Tomoda, Norio Kadowaki, Hironobu Tomoda, Manabu Moriwaki, Satoru Kadowaki
  • Publication number: 20140248407
    Abstract: A retort sterilization device includes a water steam generation device for generating water steam and a heating pot, connected to the water steam generation device, for accommodating retort food. The water steam generation device includes a heat exchanger for performing heat exchange between liquid flowing in a liquid path and heating vapor flowing in the vapor path. A top end of the liquid path of the heat exchanger is connected via a water steam supply pipe to a water steam ejection section located in an internal area of the heating pot. The heat exchanger is connected to a liquid container. A bottom end of the liquid path of the heat exchanger is connected to the liquid container via a communicating tube. The liquid container is coupled to the heating pot.
    Type: Application
    Filed: May 16, 2014
    Publication date: September 4, 2014
    Applicants: Tomoda Selling & Sailing Co., Ltd., Tomoda Fisheries Co., Ltd., Houshou Co., Ltd, Wakisangyou Yugenkaisha
    Inventors: Hiroshi TOMODA, Norio KADOWAKI, Hironobu TOMODA, Manabu MORIWAKI, Satoru KADOWAKI
  • Patent number: 8822501
    Abstract: Disclosed is a composition for use as a pest control agent, comprising a compound represented by formula (I) or an agriculturally and horticulturally acceptable salt thereof as active ingredient and an agriculturally and horticulturally acceptable carrier:
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: September 2, 2014
    Assignees: Meiji Seika Pharma Co., Ltd., The Kitasato Institute
    Inventors: Kimihiko Goto, Ryo Horikoshi, Mariko Tsuchida, Kazuhiko Oyama, Satoshi Omura, Hiroshi Tomoda, Toshiaki Sunazuka
  • Patent number: 8808638
    Abstract: A retort sterilization device includes a water steam generation device for generating water steam and a heating pot, connected to the water steam generation device, for accommodating retort food. The water steam generation device includes a heat exchanger for performing heat exchange between liquid flowing in a liquid path and heating vapor flowing in the vapor path. A top end of the liquid path of the heat exchanger is connected via a water steam supply pipe to a water steam ejection section located in an internal area of the heating pot. The heat exchanger is connected to a liquid container. A bottom end of the liquid path of the heat exchanger is connected to the liquid container via a communicating tube. The liquid container is coupled to the heating pot.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: August 19, 2014
    Assignees: Tomoda Selling & Sailing Co., Ltd., Tomoda Fisheries Co., Ltd., Houshou Co., Ltd, Wakisangyou Yugenkaisha
    Inventors: Hiroshi Tomoda, Norio Kadowaki, Hironobu Tomoda, Manabu Moriwaki, Satoru Kadowaki
  • Patent number: 8519128
    Abstract: The present invention is a compound having the general formula (I), (II), or (III) or a pharmacologically acceptable salt, solvate, or hydrate thereof, and a pharmaceutical composition containing such a compound, or its pharmacologically acceptable ester, or other pharmacologically acceptable derivative thereof as an active ingredient. The compound has an excellent ACAT 2-inhibiting activity by a mechanism different from that of a statin drug and is useful as a therapeutic or prophylactic agent for obesity, adiposis, hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, and arteriosclerosis, as well as obesity-derived hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, arteriosclerosis, and hypertension.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: August 27, 2013
    Assignee: The Kitasato Institute
    Inventors: Hiroshi Tomoda, Tohru Nagamitsu, Satoshi Omura
  • Publication number: 20130131091
    Abstract: The present invention provides a composition for use as a harmful organism control agent comprising as an active ingredient one or more of compounds represented by formula (I) or salts thereof and an agriculturally or zootechnically acceptable carrier. wherein Het represents pyridyl; X represents an oxygen atom; R1, R2, R3, R7, R10a, R10b, R11, and R12 represent a hydrogen atom; R4, R5, and R6 represent a hydrogen atom, hydroxyl, optionally substituted C1-18 alkylcarbonyloxy, optionally substituted C1-18 alkylsulfonyloxy, optionally substituted arylcarbonyloxy, C1-6 alkyloxy-C1-6 alkyloxy, C1-6 alkyloxy-C1-6 alkyloxy-C1-6 alkyloxy; R8 represents a hydrogen atom; and R13a, R13b, and R13c represent methyl.
    Type: Application
    Filed: May 23, 2011
    Publication date: May 23, 2013
    Inventors: Kimihiko Goto, Ryo Horikoshi, Kazuhiko Oyama, Yoshimasa Fukuda, Nozomu Nakanishi, Masato Tani, Nobuto Minowa, Masaaki Mitomi, Satoshi Omura, Toshiaki Sunazuka, Hiroshi Tomoda
  • Publication number: 20130085163
    Abstract: A compound effective in prevention and treatment of arteriosclerosis with a mechanism different from that of statin drugs has the following formula or a pharmaceutically acceptable salt, solvate, or hydrate thereof: wherein R1 is an aliphatic, alicyclic, or aromatic acyloxy group, or a group of the formula —13—O—CH(R7)—R8 where R7 is a lower alkoxy group and R8 is an aryl group, and R2 is carboxyl, a lower alkoxycarbonyl group, or an arylmethylcarbamoyl group, or a —CH2-acyloxy group and R3 is an aliphatic, alicyclic or aromatic acyloxy group, provided that at least one of R4 and R3 is a group other than acetoxy, or R2 and R3 taken together form a group of the formula —O—CH(R5)—O— where R5 is an aryl group.
    Type: Application
    Filed: March 25, 2011
    Publication date: April 4, 2013
    Applicant: SCHOOL JURIDICAL PERSON KITASATO INSTITUTE
    Inventors: Hiroshi Tomoda, Tohru Nagamitsu, Daisuke Matsuda, Taichi Ohshiro, Masaki Ohtawa, Satoshi Omura
  • Publication number: 20130071546
    Abstract: A retort sterilization device includes a water steam generation device for generating water steam and a heating pot, connected to the water steam generation device, for accommodating retort food. The water steam generation device includes a heat exchanger for performing heat exchange between liquid flowing in a liquid path and heating vapor flowing in the vapor path. A top end of the liquid path of the heat exchanger is connected via a water steam supply pipe to a water steam ejection section located in an internal area of the heating pot. The heat exchanger is connected to a liquid container. A bottom end of the liquid path of the heat exchanger is connected to the liquid container via a communicating tube. The liquid container is coupled to the heating pot.
    Type: Application
    Filed: September 13, 2012
    Publication date: March 21, 2013
    Applicants: TOMODA FISHERIES CO., LTD., TOMODA SELLING &SAILING CO., LTD., WAKISANGYOU YUGENKAISHA, HOUSHOU CO., LTD
    Inventors: Hiroshi TOMODA, Norio KADOWAKI, Hironobu TOMODA, Manabu MORIWAKI, Satoru KADOWAKI
  • Patent number: 8378125
    Abstract: This invention relates to substance FKI-3864 represented by the following formula [I] having an inhibitory activity on the synthesis of triacylglycerols and a method for preparing the same. The substance FKI-3864 can be prepared by a method comprising culturing a microorganism which belongs to the genus Penicillium and is capable of producing the substance FKI-3864, and particularly Penicillium pinophilum FKI-3864 (FERM BP-11093) so as to accumulate the substance FKI-3864 in the culture and collecting the substance FKI-3864 from the culture. The substance has an inhibitory activity on the synthesis of intracellular triacylglycerols and is useful for prevention or treatment of obesity.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: February 19, 2013
    Assignee: School Juridical Person Kitasato Institute
    Inventors: Hiroshi Tomoda, Ryuji Uchida, Rokuro Masuma, Satoshi Omura
  • Patent number: 8367707
    Abstract: Disclosed is a composition for use as a pest control agent, comprising a compound represented by formula (I) or an agriculturally and horticulturally acceptable salt thereof as active ingredient and an agriculturally and horticulturally acceptable carrier:
    Type: Grant
    Filed: October 13, 2010
    Date of Patent: February 5, 2013
    Assignees: Meiji Seika Pharma Co., Ltd., The Kitasato Institute
    Inventors: Kimihiko Goto, Ryo Horikoshi, Mariko Tsuchida, Kazuhiko Oyama, Satoshi Omura, Hiroshi Tomoda, Toshiaki Sunazuka
  • Publication number: 20110184173
    Abstract: The present invention is a compound having the general formula (I), (II), or (III) or a pharmacologically acceptable salt, solvate, or hydrate thereof, and a pharmaceutical composition containing such a compound, or its pharmacologically acceptable ester, or other pharmacologically acceptable derivative thereof as an active ingredient. The compound has an excellent ACAT 2-inhibiting activity by a mechanism different from that of a statin drug and is useful as a therapeutic or prophylactic agent for obesity, adiposis, hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, and arteriosclerosis, as well as obesity-derived hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, arteriosclerosis, and hypertension.
    Type: Application
    Filed: December 17, 2008
    Publication date: July 28, 2011
    Applicant: THE KITASATO INSTITUTE
    Inventors: Hiroshi Tomoda, Tohru Nagamitsu, Satoshi Omura
  • Patent number: 7982057
    Abstract: The present invention relates to novel compound of stemphones obtained by culturing microorganism belonging to genus Aspergillus and having ability to produce compound of stemphones selected from the group consisting of stemphone D substance, stemphone E substance, stemphone E1 substance, stemphone E2 substance, stemphone E3 substance and stemphone F substance, accumulating the compound of stemphones in the cultured mass, and isolating the compound of stemphones from the cultured mass. Since the obtained compound has enhancing activity for imipenem and activity for reducing cytotoxicity, it can be expected to be useful as lead compounds for combination remedy for methicillin resistant Staphylococcus aureus (MRSA) infection.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: July 19, 2011
    Assignee: The Kitasato Institute
    Inventors: Satoshi Omura, Hiroshi Tomoda, Rokuro Masuda
  • Patent number: 7973147
    Abstract: A microorganism represented by a strain K04-0144 belonging to Streptomyces sp. having ability to produce K04-0144 substance is cultured in the medium, and the isolated K04-0144A substance, K04-0144B substance and K04-0144C substance therefrom have strong antibacterial activities against Gram-positive bacteria including methicillin-resistant Streptococcus aureus (MRSA), consequently these are useful as the therapeutic agents for infectious disease caused by MRSA as well as infectious diseases caused by multidrug including ?-lactam antibiotics resistant bacteria. Further, similarly, since the novel K04-0144D substance isolated from the cultured liquid has the action for enhancing the effect of ?-lactam antibiotics, which are utilized as the antibacterial agents, in combination with them, it is useful as the therapeutic agent for infectious diseases caused by methicillin-resistant Staphylococcus aureus (MRSA) and multidrug including ?-lactam antibiotics resistant bacteria.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: July 5, 2011
    Assignee: The Kitasato Institute
    Inventors: Satoshi Omura, Hiroshi Tomoda, Yong-pil Kim, Hideaki Hanaki, Atsuko Matsumoto, Yoko Takahashi
  • Publication number: 20110105769
    Abstract: This invention relates to substance FKI-3864 represented by the following formula [I] having an inhibitory activity on the synthesis of triacylglycerols and a method for preparing the same. The substance FKI-3864 can be prepared by a method comprising culturing a microorganism which belongs to the genus Penicillium and is capable of producing the substance FKI-3864, and particularly Penicillium pinophilum FKI-3864 (FERM BP-11093) so as to accumulate the substance FKI-3864 in the culture and collecting the substance FKI-3864 from the culture. The substance has an inhibitory activity on the synthesis of intracellular triacylglycerols and is useful for prevention or treatment of obesity.
    Type: Application
    Filed: February 12, 2009
    Publication date: May 5, 2011
    Applicant: SCHOOL JURIDICAL PERSON KITASATO INSTITUTE
    Inventors: Hiroshi Tomoda, Ryuji Uchida, Rokuro Masuma, Satoshi Omura
  • Publication number: 20110034404
    Abstract: Disclosed is a composition for use as a pest control agent, comprising a compound represented by formula (I) or an agriculturally and horticulturally acceptable salt thereof as active ingredient and an agriculturally and horticulturally acceptable carrier:
    Type: Application
    Filed: October 13, 2010
    Publication date: February 10, 2011
    Inventors: Kimihiko GOTO, Ryo Horikoshi, Mariko Tsuchida, Kazuhiko Oyama, Satoshi Omura, Hiroshi Tomoda, Toshiaki Sunazuka