Patents by Inventor Hiroshi Yanagawa
Hiroshi Yanagawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10845739Abstract: To provide a manufacturing method and a manufacturing device for a peeling member capable of manufacturing the peeling member having less variation in quality and excellent durability for long-time use at a low cost with excellent productivity by a simple structure. The manufacturing method for the peeling member includes sticking a non-adhesive resin film. In sticking the non-adhesive resin film, a distal end edge 2b of a distal end portion 2a of a base material 2 is arranged at a side of an adhesive layer of a non-adhesive resin film 4 such that an end portion of the non-adhesive resin film 4 is protruded from the distal end edge 2b, and then the non-adhesive resin film 4 is stuck on both surfaces of the distal end portion 2a of a base material 2 to wrap the distal end edge 2b of the base material 2 by pressing a plurality rollers 21 to 25 sequentially onto the non-adhesive resin film 4 from an one side end portion toward an another side end portion in a longitudinal direction of the base material 2.Type: GrantFiled: September 16, 2016Date of Patent: November 24, 2020Assignee: NTN CORPORATIONInventors: Kazuo Hirose, Hiroshi Yanagawa
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Publication number: 20200241451Abstract: To provide a manufacturing method and a manufacturing device for a peeling member capable of manufacturing the peeling member having less variation in quality and excellent durability for long-time use at a low cost with excellent productivity by a simple structure. The manufacturing method for the peeling member includes sticking a non-adhesive resin film. In sticking the non-adhesive resin film, a distal end edge 2b of a distal end portion 2a of a base material 2 is arranged at a side of an adhesive layer of a non-adhesive resin film 4 such that an end portion of the non-adhesive resin film 4 is protruded from the distal end edge 2b, and then the non-adhesive resin film 4 is stuck on both surfaces of the distal end portion 2a of a base material 2 to wrap the distal end edge 2b of the base material 2 by pressing a plurality rollers 21 to 25 sequentially onto the non-adhesive resin film 4 from an one side end portion toward an another side end portion in a longitudinal direction of the base material 2.Type: ApplicationFiled: September 16, 2016Publication date: July 30, 2020Inventors: Kazuo HIROSE, Hiroshi YANAGAWA
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Publication number: 20190315775Abstract: A phenylphthalimide derivative represented by the following general formula is provided as a phenylphthalimide derivative useful against various cancers including multiple myeloma, wherein R1 is a group containing PEG or a hydroxy C1-5 alkoxy group binding to position 4 or position 5, R2 is an amino group at position 6, and R3 and R4 are each independently a hydrogen atom, an alkyl group, an aryl group, an aralkyl group, or an aryloxy group.Type: ApplicationFiled: October 19, 2017Publication date: October 17, 2019Applicants: KEIO UNIVERSITY, IDAC THERANOSTICS, INC.Inventors: Yutaka HATTORI, Maiko MATSUSHITA, Daiju ICHIKAWA, Shuji AIDA, Takeshi SUGAI, Taketo YAMADA, Hiroshi YANAGAWA, Yoko OGAWA, Noriko TABATA, Yuko YONEMURA
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Publication number: 20180275571Abstract: Relating to a sliding member for a fixing device having a resin coating film on a sliding surface, to provide a manufacturing method for the peeling member for the fixing device capable of forming a fine recessed groove as a lubricant reservoir on a surface of the resin coating film. The manufacturing method for the sliding member for the fixing device includes a coating film forming step of forming a resin coating film by drying a resin coating material after applying the resin coating material including a matrix resin on at least a sliding surface of the base material of the sliding member slid on the belt member, a coating film baking step of baking and hardening the resin coating film, and a recessed portion forming step of forming a recessed portion, which becomes a lubricant reservoir when the coating film baking step is performed, on the surface of the resin coating film, after the coating film forming step and before the coating film baking step.Type: ApplicationFiled: September 15, 2016Publication date: September 27, 2018Inventors: Kazuo HIROSE, Hiroshi YANAGAWA, Yoshihide HIMENO
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Patent number: 10036984Abstract: To provide a manufacturing method for a peeling member in which a non-adhesive resin film formed by fluororesin resin or the like is adhered to a metal plate, the method capable of manufacturing the peeling member which can prevent adhesion of a paper right after fixing for a long period of time with high productivity and without variations in quality. The manufacturing method for the peeling member provided with a peeling sheet 1a formed by a metal plate 2 and a non-adhesive resin film 4 adhered to the metal plate 2, the manufacturing method including a groove forming step of forming a pattern portion 5 formed by a plurality of recessed grooves on at least a part of a paper passing side surface of the non-adhesive resin film 4 along a longitudinal direction of the non-adhesive resin film 4.Type: GrantFiled: December 18, 2015Date of Patent: July 31, 2018Assignee: NTN CORPORATIONInventors: Kazuo Hirose, Hiroshi Yanagawa, Yuuki Yamazoe
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Patent number: 9915292Abstract: A drawer pull-out guide includes a carcass rail to be fixed to a furniture carcass, an extension rail displaceable relative to the carcass rail between a closed position and an open position, and a rolling body and a supporting body movable along a running limb of the carcass rail and a running surface of the extension rail upon a movement of the extension rail. A clearance is formed on the running limb of the carcass rail and/or on the running surface of the extension rail. The rolling body is accommodated within the clearance in the closed position of the extension rail and is thereby relieved from the load of the extension rail. In the closed position of the extension rail, the load of the extension rail is carried by the rolling body. The rolling body and the supporting body are arranged in a common running carriage.Type: GrantFiled: April 25, 2014Date of Patent: March 13, 2018Assignee: NTN CORPORATIONInventors: Hiroshi Yanagawa, Kazuo Hirose
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Publication number: 20170357195Abstract: To provide a manufacturing method for a peeling member in which a non-adhesive resin film formed by fluororesin resin or the like is adhered to a metal plate, the method capable of manufacturing the peeling member which can prevent adhesion of a paper right after fixing for a long period of time with high productivity and without variations in quality.Type: ApplicationFiled: December 18, 2015Publication date: December 14, 2017Inventors: Kazuo HIROSE, Hiroshi YANAGAWA, Yuuki YAMAZOE
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Patent number: 9367018Abstract: An image forming device includes a tripod type constant-velocity joint through which a rotary member shaft of a rotary member is connected to the drive shaft of a motor. The constant-velocity joint includes a pair of outer rings each having three axially extending track grooves in its inner periphery, and a tripod member having three protrusions formed on each of the axial ends thereof and axially slidably received in the corresponding track grooves. The outer rings and the tripod member are formed of synthetic resin. One of the outer rings and the tripod member are inseparably coupled to the drive shaft so that the other of the outer rings is always disconnected from the tripod member when the rotary member is pulled away from the motor.Type: GrantFiled: May 14, 2015Date of Patent: June 14, 2016Assignees: NTN CORPORATION, RICOH COMPANY, LTD.Inventors: Hiroshi Yanagawa, Kazuo Hirose, Hiroaki Takagi, Junichi Ichikawa
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Publication number: 20160102714Abstract: A tripod type constant-velocity joint is provided through which a driving shaft is coupled to a driven shaft. The joint includes two outer rings connected to the driving shaft and the driven shaft, respectively, and a tripod member through which the outer rings are coupled together. Each of the outer rings has an inner periphery formed with three axially extending track grooves arranged at angular intervals of 120 degrees. The tripod member has two axial ends each formed with three protrusions axially slidably received in the respective track grooves of the corresponding one of the outer rings, whereby torque around an axis is transmitted between the respective outer rings and the tripod member. The joint can thus cope with a larger angle and/or offset between the axis of the driving shaft and the axis of the driven shaft.Type: ApplicationFiled: April 25, 2014Publication date: April 14, 2016Inventors: Hiroshi YANAGAWA, Kazuo HIROSE
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Patent number: 8278427Abstract: An assigning molecule obtained by ligating a genotype molecule to a phenotype molecule by transpeptidation, wherein the genotype molecule is constructed by bonding (a) a spacer molecule comprising a donor region which can be bonded to a 3?-terminal end of nucleic acid, a PEG region bonded to the donor region and a peptide acceptor region which is bonded to the PEG region, to (b) a 3? end of a nucleic acid comprising a 5? untranslated region comprising a transcription promoter and a translation enhancer; an ORF region which comprises a polyA sequence and which is bonded to the 3?-terminal side of the 5? untranslated region; and a 3?-terminal region that is bonded to the 3?-terminal side of the ORF region.Type: GrantFiled: June 13, 2003Date of Patent: October 2, 2012Assignee: KEIO UniversityInventors: Hiroshi Yanagawa, Etsuko Miyamoto, Hideaki Takashima
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Patent number: 8200516Abstract: A management computer (21) is placed in a home country, and an instructor terminal (31) and a driver terminal (32) are placed in a delivery area overseas. The management computer (21) generates screen information, displayed in a domestic language and including a delivery instruction for a package, and transmits the screen information toward the instructor terminal (31) and the driver terminal (32). The instructor terminal (31) or the like, specifies a language, to be used in an area to which a delivery destination belongs, from the address of the delivery destination included in the delivery instruction in the received screen information, and translates the screen information in the specified language, then displays it. When a display language is designated, the instructor terminal (31) or the like translates the screen information in the designated language and displays it.Type: GrantFiled: March 12, 2004Date of Patent: June 12, 2012Assignee: Ricoh Company, Ltd.Inventors: Mitsuo Tomioka, Hiroshi Yanagawa, Yukio Yamamoto, Mitsuaki Taniguchi, Tetsuji Aoki, Kazunori Uchiyama, Tomoyuki Nakayama, Dai Suzuki, Takeshi Eguchi
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Patent number: 7838243Abstract: Comprehensive analysis of transcription control factor complexes in a mouse brain cDNA library with c-Jun as a bait by using the cotranslation selection and screening of in vitro virus (IVV) and the C-terminal labeling method are conducted, thereby to provide known and unknown proteins which are unknown to form a complex with the c-Jun protein, whereby proteins that interact with c-Jun, nucleic acids encoding them and inhibitors utilizing them as well as methods for detecting an interaction and screening methods are provided.Type: GrantFiled: November 19, 2004Date of Patent: November 23, 2010Assignee: Keio UniversityInventors: Etsuko Miyamoto, Kenichi Horisawa, Hiroshi Yanagawa
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Patent number: 7670787Abstract: Proteins that interact with c-Fos, nucleic acids encoding them and inhibitors utilizing them as well as methods for detecting an interaction and screening methods utilizing a protein that interacts with c-Fos are provided. Comprehensive analysis of transcription control factor complexes in a mouse brain cDNA library with c-Fos as a bait by using the cotranslation selection and screening of in vitro virus (IVV) and the C-terminal labeling method are conducted, thereby to analyze proteins unknown so far, proteins known so far, but unknown to form a complex with the c-Fos protein, and so forth.Type: GrantFiled: October 29, 2007Date of Patent: March 2, 2010Assignee: Keio UniversityInventors: Etsuko Miyamoto, Masamichi Ishizaka, Hiroshi Yanagawa
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Publication number: 20080177030Abstract: Proteins that interact with c-Fos, nucleic acids encoding them and inhibitors utilizing them as well as methods for detecting an interaction and screening methods utilizing a protein that interacts with c-Fos are provided. Comprehensive analysis of transcription control factor complexes in a mouse brain cDNA library with c-Fos as a bait by using the cotranslation selection and screening of in vitro virus (IVV) and the C-terminal labeling method are conducted, thereby to analyze proteins unknown so far, proteins known so far, but unknown to form a complex with the c-Fos protein, and so forth.Type: ApplicationFiled: October 29, 2007Publication date: July 24, 2008Inventors: Etsuko Miyamoto, Masamichi Ishizaka, Hiroshi Yanagawa
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Publication number: 20070003534Abstract: Comprehensive analysis of transcription control factor complexes in a mouse brain cDNA library with c-Jun as a bait by using the cotranslation selection and screening of in vitro virus (IVV) and the C-terminal labeling method are conducted, thereby to provide known and unknown proteins which are unknown to form a complex with the c-Jun protein, whereby proteins that interact with c-Jun, nucleic acids encoding them and inhibitors utilizing them as well as methods for detecting an interaction and screening methods are provided.Type: ApplicationFiled: November 19, 2004Publication date: January 4, 2007Inventors: Etsuko Miyamoto, Kenichi Horisawa, Hiroshi Yanagawa
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Patent number: 7150978Abstract: A translation template comprising an ORF region coding for a protein, a 5? untranslated region comprising a transcription promoter and a translation enhancer and locating on the 5? side of the ORF region, and a 3? end region comprising a poly-A sequence and locating on the 3? side of the ORF region, is expressed in a translation system in the presence of an agent for modifying a C-terminal of a protein, which comprises an acceptor portion having a group capable of binding to a protein through a transpeptidation reaction in a protein translation system and a modifying portion comprising a nonradioactive modifying substance linked to the acceptor portion via a nucleotide linker, to cause protein synthesis and the synthesized protein is purified. Thus, the yield of modified protein in a method of modifying C-terminal of protein is improved and detection of protein interaction based on various intermolecular interaction detection methods is realized at an improved level.Type: GrantFiled: June 6, 2003Date of Patent: December 19, 2006Assignee: Keio UniversityInventors: Hiroshi Yanagawa, Nobuhide Doi, Etsuko Miyamoto, Hideaki Takashima, Rieko Oyama
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Publication number: 20060224393Abstract: A management computer (21) is placed in a home country, and an instructor terminal (31) and a driver terminal (32) are placed in a delivery area overseas. The management computer (21) generates screen information, displayed in a domestic language and including a delivery instruction for a package, and transmits the screen information toward the instructor terminal (31) and the driver terminal (32). The instructor terminal (31) or the like, specifies a language, to be used in an area to which a delivery destination belongs, from the address of the delivery destination included in the delivery instruction in the received screen information, and translates the screen information in the specified language, then displays it. When a display language is designated, the instructor terminal (31) or the like translates the screen information in the designated language and displays it.Type: ApplicationFiled: March 12, 2004Publication date: October 5, 2006Inventors: Mitsuo Tomioka, Hiroshi Yanagawa, Yukio Yamamoto, Mitsuaki Taniguchi, Tetsuji Aoki, Kazunori Uchiyama, Tomoyuki Nakayama, Dai Suzuki, Takeshi Eguchi
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Publication number: 20060210982Abstract: A method for screening a nucleic acid library for a nucleic acid encoding a protein that interacts with a target substance, which comprises: the step of producing a library of assigning molecules each comprising a protein and a nucleic acid encoding the protein linked to each other via a linker cleavable under a condition that does not change a nucleotide sequence of the nucleic acid; the step of mixing the library of assigning molecules and the target substance; the step of separating an assigning molecule binding to the target substance; the step of cleaving a linker of the separated assigning molecule under a condition that does not change a nucleotide sequence of the nucleic acid to release the nucleic acid; and the step of collecting the released nucleic acid. By this method, screening for an assigning molecule that specifically binds to a target substance can be conducted with high efficiency.Type: ApplicationFiled: February 2, 2004Publication date: September 21, 2006Inventors: Hiroshi Yanagawa, Nobuhide Doi, Tetsuya Nagano, Hideaki Takashima
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Publication number: 20060183885Abstract: Proteins that interact with c-Fos, nucleic acids encoding them and inhibitors utilizing them as well as methods for detecting an interaction and screening methods utilizing a protein that interacts with c-Fos are provided. Comprehensive analysis of transcription control factor complexes in a mouse brain cDNA library with c-Fos as a bait by using the cotranslation selection and screening of in vitro virus (IVV) and the C-terminal labeling method are conducted, thereby to analyze proteins unknown so far, proteins known so far, but unknown to form a complex with the c-Fos protein, and so forth.Type: ApplicationFiled: November 19, 2003Publication date: August 17, 2006Inventors: Etsuko Miyamoto, Masamichi Ishizaka, Hiroshi Yanagawa
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Patent number: 7041446Abstract: A protein having a labeling compound attached to its C-terminal, in which the compound comprises a label portion comprising a label substance and an acceptor portion comprising a compound having an ability of binding to a C-terminal of a synthesized protein when protein synthesis is carried out in a cell-free protein synthesis system or in a living cell is provided. Also, a method for producing the protein comprising the step of performing synthesis of a protein in a cell-free protein synthesis system or in a living cell in the presence of a labeling compound comprising a label portion comprising a label substance and an acceptor portion comprising a compound having an ability of binding to a C-terminal of a synthesized protein when protein synthesis is carried out in the cell-free protein synthesis system or in the living cell, the labeling compound being present at a concentration effective for the labeling compound to bind to the C-terminal of the synthesized protein is provided.Type: GrantFiled: February 28, 2001Date of Patent: May 9, 2006Assignee: Mitsubishi Chemical CorporationInventors: Hiroshi Yanagawa, Naoto Nemoto, Etsuko Miyamoto