Patents by Inventor Hiroyuki Ebinuma

Hiroyuki Ebinuma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070146184
    Abstract: A signal processing circuit includes an auto gain control circuit and amplifies a signal with an amplification ratio determined based on a synchronous signal level having a positive potential with respect to a black level included in a high definition television video signal. In consequence, during the processing of the high definition television video signal, the signal processing is performed with a desired amplification ratio.
    Type: Application
    Filed: December 20, 2006
    Publication date: June 28, 2007
    Applicant: Sanyo Electric Co., Ltd.
    Inventors: Toru Okada, Hiroyuki Ebinuma
  • Patent number: 7198905
    Abstract: The present invention provides a screening method by which a prediabetic state can be more accurately determined and many test samples can be treated without physical burden on patients, and a diagnostic reagent used for it. By measuring a D-mannose concentration, preferably a D-mannose concentration and a glucose concentration, in a body fluid collected from a subject, and comparing them with their respective standard values, a patient in a prediabetic state can be detected. Further, the measurement of the mannose concentration is conducted by allowing an enzyme having an oxidizing activity on mannose by dehydrogenation to react on the mannose in a sample in the presence of an electron acceptor, and quantitatively determining the formed reductant of the electron acceptor.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: April 3, 2007
    Assignees: Daiichi Pure Chemicals Co., Ltd.
    Inventors: Hiroyuki Ebinuma, Kazunori Saito, Hirohito Sone, Nobuhiro Yamada
  • Patent number: 7198890
    Abstract: The present invention provides a method for quantitatively determining homocysteine in a biological specimen containing homocysteine and cysteine by use of an enzyme which is capable of forming hydrogen sulfide both from homocysteine and from cysteine, which comprises (a) reacting the biological specimen with cysteine dioxygenase in the absence of a reducing agent, (b) subsequently reacting the resultant specimen of (a) with a reducing agent and the enzyme which is capable of forming hydrogen sulfide both from homocysteine and from cysteine, and (c) measuring the concentration of the hydrogen sulfide thus obtained to determine the homocysteine concentration in the biological specimen; and a reagent for such a quantitative determination of homocysteine.
    Type: Grant
    Filed: January 13, 2004
    Date of Patent: April 3, 2007
    Assignee: Daiichi Pure Chemicals Co., Ltd.
    Inventors: Hiroyuki Ebinuma, Takami Sarashina, Takuji Matsumoto, Masahiro Sekiguchi, Koji Ushizawa
  • Publication number: 20070065891
    Abstract: The invention provides a method of pretreating a sample for conveniently, quickly and accurately measuring the total amount of adiponectin present in a biological sample contaminated with various adiponectin multimers. The method of measuring an sample for immunologically assaying the total amount of adiponectin present in the sample comprises reacting, with an adiponectin-containing sample, at least one of a reducing agent, an acid or a salt thereof, a surfactant, and a protease.
    Type: Application
    Filed: October 15, 2004
    Publication date: March 22, 2007
    Applicants: DAIICHI PURE CHEMICALS CO., LTD., TOUDAI TLO, LTD.
    Inventors: Hiroyuki Ebinuma, Hirokazu Yago, Yuka Akimoto, Osamu Miyazaki, Takashi Kadowaki, Toshimasa Yamauchi
  • Publication number: 20070054344
    Abstract: The present invention is directed to a defructosylation enzyme originating from a plant, a method of defructosylating a fructosylated peptide or protein through use of the enzyme, and a method of measuring a fructosylated peptide or protein.
    Type: Application
    Filed: October 23, 2003
    Publication date: March 8, 2007
    Applicant: DAIICHI PURE CHEMICALS CO., LTD.
    Inventor: Hiroyuki Ebinuma
  • Publication number: 20070042424
    Abstract: We have discovered a “human adiponectin ELISA kit”, which can specifically measure adiponectin in human blood serum (or blood plasma) or in extracted fluid from lipocytes or culture supernatant fluid. After fractioning human serum by use of gel filtration column, each fraction was measured by the present kit, and as a result, adiponectin immunity activity was detected as a plurality of peaks at above 670 kD of molecular weight. From the results, it is presumed that adiponectin is present in the blood as a polymer or forms a complex with polymer proteins.
    Type: Application
    Filed: October 15, 2004
    Publication date: February 22, 2007
    Applicants: DAIICHI PURE CHEMICALS CO., LTD., TOUDAI TLO, LTD.
    Inventors: Hiroyuki Ebinuma, Hirokazu Yago, Yuka Akimoto, Osamu Miyazaki, Takashi Kadowaki, Toshimasa Yamauchi, Kazuo Hara
  • Publication number: 20060240501
    Abstract: The present invention is directed to a defructosylation enzyme originating from a plant, a method of defructosylating a fructosylated peptide or protein through use of the enzyme, and a method of measuring a fructosylated peptide or protein.
    Type: Application
    Filed: October 23, 2003
    Publication date: October 26, 2006
    Applicant: Daiichi Pure Chemicals Co., Ltd.
    Inventor: Hiroyuki Ebinuma
  • Publication number: 20060072040
    Abstract: A video signal processing circuit is supplied with an analog composite video signal formed by combining at least a luminance signal with a sync signal, and processes the analog composite video signal. The video signal processing circuit has an analog filter which removes high-frequency components from the analog composite video signal, a sync separation circuit which separates a sync signal from an output signal from the analog filter, an AD converter which performs AD conversion on the analog composite video signal, and a digital video signal processing circuit which performs predetermined video signal processing on the composite video signal digitized by the AD converter, by using the sync signal obtained by the sync separation circuit.
    Type: Application
    Filed: October 4, 2005
    Publication date: April 6, 2006
    Applicant: Sanyo Electric Co., Ltd.
    Inventors: Ikuo Osawa, Yoshifumi Yoshida, Hiroyuki Ebinuma, Toru Okada
  • Patent number: 6969613
    Abstract: The present invention provides a method for quantitatively determining hydrogen sulfide or sulfide ions conveniently with high sensitivity, which comprises adding to a sample containing hydrogen sulfide or sulfide ions, metal ions or a compound which liberates said metal ions and a metal indicator which reacts with the metal ions and resultingly undergoes color development, wherein the color development is accelerated or inhibited by the hydrogen sulfide or sulfide ions; and measuring the degree of color development of the metal indicator.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: November 29, 2005
    Assignee: Daiichi Pure Chemicals Co., Ltd.
    Inventors: Hiroyuki Ebinuma, Koji Ushizawa
  • Publication number: 20050164330
    Abstract: A method for quantitatively determining a specific component in a biological specimen, which includes reacting a biological specimen, in the presence of an electron acceptor, with an enzyme which has an ability, by the dehydrogenation reaction, to oxidize the specific component or a substance derived from the specific component, and measuring the formed reductant of the electron acceptor, wherein the method avoids the influence of hemoglobin effectively if any contained in the specimen by using a measuring reagent containing albumin, thereby making an quantitative determination of the target component accurately; and a reagent for the quantitative determination.
    Type: Application
    Filed: January 27, 2004
    Publication date: July 28, 2005
    Applicant: DAIICHI PURE CHEMICALS CO., LTD.
    Inventors: Hiroyuki Ebinuma, Kumiko Yuki
  • Publication number: 20050153385
    Abstract: The present invention provides a method for quantitatively determining homocysteine in a biological specimen containing homocysteine and cysteine by use of an enzyme which is capable of forming hydrogen sulfide both from homocysteine and from cysteine, which comprises (a) reacting the biological specimen with cysteine dioxygenase in the absence of a reducing agent, (b) subsequently reacting the resultant specimen of (a) with a reducing agent and the enzyme which is capable of forming hydrogen sulfide both from homocysteine and from cysteine, and (c) measuring the concentration of the hydrogen sulfide thus obtained to determine the homocysteine concentration in the biological specimen; and a reagent for such a quantitative determination of homocysteine.
    Type: Application
    Filed: January 13, 2004
    Publication date: July 14, 2005
    Applicant: DAIICHI PURE CHEMICALS CO., LTD.
    Inventors: Hiroyuki Ebinuma, Takami Sarashina, Takuji Matsumoto, Masahiro Sekiguchi, Koji Ushizawa
  • Publication number: 20050148089
    Abstract: The present invention provides a method for quantitatively determining a reducing substance, which comprises reacting a reducing substance in a test specimen with iron (III) ions, reacting iron (II) ions formed by reduction of the iron (III) ions or residual iron (III) ions with a metal indicator which is capable of reacting specifically with the iron (II) ions or the residual iron (III) ions to undergo color development, and carrying out quantitative determination by measuring the degree of color development, wherein a chelating agent which is specific to copper ions is added to the test specimen before the reaction of the reducing substance with the iron (III) ions; and a reagent used for it.
    Type: Application
    Filed: December 24, 2003
    Publication date: July 7, 2005
    Applicant: DAIICHI PURE CHEMICALS CO., LTD.
    Inventors: Masahiro Sekiguchi, Takuji Matsumoto, Hiroyuki Ebinuma
  • Publication number: 20040110246
    Abstract: The present invention provides a screening method by which a prediabetic state can be more accurately determined and many test samples can be treated without physical burden on patients, and a diagnostic reagent used for it.
    Type: Application
    Filed: September 15, 2003
    Publication date: June 10, 2004
    Inventors: Hiroyuki Ebinuma, Kazunori Saito, Hirohito Sone, Nobuhiro Yamada
  • Patent number: 6541215
    Abstract: Disclosed are a method for quantitatively determining mannose, which comprises reacting mannose in a specimen with an enzyme which is capable of oxidizing the mannose by dehydrogenation, in the presence of an electron acceptor, and quantitatively determining a formed reductant of the electron acceptor; and a reagent for the quantitative determination of mannose.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: April 1, 2003
    Assignee: Daiichi Pure Chemicals Co., Ltd.
    Inventors: Hiroyuki Ebinuma, Koji Ushizawa
  • Patent number: 5871949
    Abstract: Using a 1,5-anhydroglucitol dehydrogenase capable of acting on 1,5-anhydroglucitol and directly catalyzing a reducing chromophoric agent in the absence of an electron carrier, the 1,5-anhydroglucitol dehydrogenase is allowed to act on 1,5-anhydroglucitol in the presence of the reducing chromophoric agent preferably after the glucose in the specimen has been changed, or while being changed, into such a structure that it does not react with the 1,5-anhydroglucitol dehydrogenase in the specimen, by the aid of a glucose eliminator. Then, the amount of the resultant reduced colored substance is measured. As the 1,5-anhydroglucitol dehydrogenase, an enzyme produced by a microorganism having the ability to produce the 1,5-anhydroglucitol dehydrogenase is preferably used.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: February 16, 1999
    Assignee: Daiichi Pure Chemicals Co., Ltd.
    Inventors: Hiroyuki Ebinuma, Koji Ushizawa