Patents by Inventor Hiroyuki Kishi

Hiroyuki Kishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10065515
    Abstract: On the ground, a plurality of primary power supply transformers are separately installed with a longitudinal direction of magnetic poles matching a vehicle traveling direction. The primary power supply transformers each include a double-sided coil with an H-shaped core around which a wire is wound. On a vehicle, a secondary power supply transformer including an H-shaped core is mounted with a longitudinal direction of magnetic poles matching a vehicle front-back direction. The distance between the primary power supply transformers is set such that the distance between the centers of the magnetic poles of the neighboring primary power supply transformers does not exceed 3D where D represents the size of the magnetic poles.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: September 4, 2018
    Assignee: TECHNOVA INC.
    Inventors: Tomio Yasuda, Hiroyuki Kishi, Isami Norigoe
  • Patent number: 9977017
    Abstract: Provided are a method and means permitting the simultaneous measurement of the reactive properties of more than 10,000 of antigen-stimulated lymphocytes being held on a chip and the separate determination of the states of individual cells. A microwell array comprises multiple wells and a coating layer on one of the principal surfaces of a base member, the wells being of a size permitting the entry of only a single cell into each well. A coating layer of a substance capable of binding to a substance produced by the cells contained in the wells is present on the principal surface around the wells.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: May 22, 2018
    Assignees: TOYAMA PREFECTURE, VALNEVA
    Inventors: Aishun Jin, Hiroyuki Kishi, Atsushi Muraguchi, Tsutomu Obata
  • Patent number: 9793045
    Abstract: According to one embodiment, contactless power transfer transformer includes power transmission coil and power reception coil. At least one of the power transmission coil and the power reception coil is configured by coupled and both-sides wound coil. The coupled and both-sides wound coil is configured by both-sides wound coils. One of magnetic poles of one of the both-sides wound coils is connected to one of the magnetic poles of adjacent one of the both-sides wound coils. Directions of magnetic fluxes toward corresponding coil from each of the magnetic poles connected to each other are identical. The both-sides wound coils are selected so that leakage magnetic flux around moving body does not exceed predetermined value. Number of the both-sides wound coils is set so that value obtained by multiplying power transfer capacity of one of the both-sides wound coils by the number satisfies capacity of the transformer.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: October 17, 2017
    Assignee: TECHNOVA INC.
    Inventors: Shigeru Abe, Yasuyoshi Kaneko, Tomio Yasuda, Hiroyuki Kishi
  • Publication number: 20170183700
    Abstract: As a method for highly efficiently amplifying a TCR cDNA in a short period of time, there is provided a method for amplifying a T cell receptor (TCR) cDNA, which comprises the following step (1) and step (2): (1) the step of performing PCR by using at least one kind of the L primer mentioned below, the C primer 1 or UTR primer 1 mentioned below, and cDNA obtained from a single cell as the template to obtain an amplification product 1; an L primer of 30- to 60-nucleotide length comprising an adapter part of 15- to 25-nucleotide length, and a leader region-annealing part of 15- to 25-nucleotide length, which is ligated downstream from the adapter part, and can anneal to a part of a leader region containing a translation initiation codon, or an upstream part thereof, a C primer 1 of 15- to 25-nucleotide length, which can anneal to a part of a constant region, or a UTR primer 1 of 15- to 25-nucleotide length, which can anneal to a part of a 3? untranslated region; (2) the step of performing PCR by using the a
    Type: Application
    Filed: May 29, 2015
    Publication date: June 29, 2017
    Inventors: Hiroshi HAMANA, Hiroyuki KISHI, Atsushi MURAGUCHI, Kiyomi SHITAOKA
  • Publication number: 20170166904
    Abstract: The purpose of the invention is to provide means with which it is possible to efficiently select a vector to which a foreign gene has been introduced when a foreign gene is to be introduced by homologous recombination to a vector having multiple sequences homologous with one another. The vector comprises, in succession, a replication origin, a sequence A, a marker gene X, two sequences C and D for introducing a foreign gene by homologous recombination, and a sequence B homologous with sequence A. The two sequences C and D are directly or indirectly adjacent to one another. The vector is used for introducing a foreign gene between the two adjacent sequences C and D.
    Type: Application
    Filed: December 7, 2016
    Publication date: June 15, 2017
    Inventors: Masae HORII, Hiroyuki KISHI, Eiji KOBAYASHI, Tatsuhiko OZAWA, Atsushi MURAGUCHI
  • Publication number: 20170158064
    Abstract: On the ground, a plurality of primary power supply transformers are separately installed with a longitudinal direction of magnetic poles matching a vehicle traveling direction. The primary power supply transformers each include a double-sided coil with an H-shaped core around which a wire is wound. On a vehicle, a secondary power supply transformer including an H-shaped core is mounted with a longitudinal direction of magnetic poles matching a vehicle front-back direction. The distance between the primary power supply transformers is set such that the distance between the centers of the magnetic poles of the neighboring primary power supply transformers does not exceed 3D where D represents the size of the magnetic poles.
    Type: Application
    Filed: March 4, 2014
    Publication date: June 8, 2017
    Applicant: TECHNOVA INC.
    Inventors: Tomio YASUDA, Hiroyuki KISHI, Isami NORIGOE
  • Patent number: 9624971
    Abstract: The motion guide device includes a track member in which a rolling member rolling surface is formed along a longitudinal direction thereof, a movable member which is reciprocally movable with a number of rolling members being interposed therebetween and which is provided with a loaded rolling member rolling surface constituting a loaded rolling member rolling path opposing to the rolling member rolling surface and a rolling member return path, and a lid member provided with a pair of direction changing paths for connecting both end portions of the loaded rolling member rolling path and the rolling member return path to thereby constitute an endless circulation path. Flange portions are formed to both end portions of the movable member in the reciprocally moving direction by means of insert molding, and the flange portions are provided with fitting portions formed to end portion sides of the movable member.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: April 18, 2017
    Assignee: THK CO., LTD.
    Inventors: Nobuyuki Ikegami, Fumiaki Morita, Yoshiaki Iwashige, Yasuhiro Suga, Mitsumasa Wada, Hiroyuki Kishi
  • Publication number: 20170023562
    Abstract: Provided are a method and means permitting the simultaneous measurement of the reactive properties of more than 10,000 of antigen-stimulated lymphocytes being held on a chip and the separate determination of the states of individual cells. A microwell array comprises multiple wells and a coating layer on one of the principal surfaces of a base member, the wells being of a size permitting the entry of only a single cell into each well. A coating layer of a substance capable of binding to a substance produced by the cells contained in the wells is present on the principal surface around the wells.
    Type: Application
    Filed: October 4, 2016
    Publication date: January 26, 2017
    Inventors: Aishun JIN, Hiroyuki KISHI, Atsushi MURAGUCHI, Tsutomu OBATA
  • Patent number: 9502176
    Abstract: A contactless power transfer transformer includes main body. The main body includes magnetic pole core members, winding wire core member, and wire. The winding wire core member is orthogonal to the magnetic pole core members and connects one portion of each of the pair of parallel magnetic pole core members with each other. The main body is fixed to fixing plate having a magnetic shield function and heat dissipation function. The connecting position of the winding wire core member with respect to the magnetic pole core members is located toward one side from a center in the longitudinal direction of the magnetic pole core members. At least a space between the pair of the magnetic coil core members each containing an end portion longer in distance to the connecting position is used as an arrangement space of component electrically connected to the electric wire.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: November 22, 2016
    Assignee: TECHNOVA INC.
    Inventors: Tomio Yasuda, Hiroyuki Kishi, Isami Norigoe
  • Patent number: 9494575
    Abstract: Provided are a method and means permitting the simultaneous measurement of the reactive properties of more than 10,000 of antigen-stimulated lymphocytes being held on a chip. A microwell array comprises multiple wells capturing single cells and a coating layer on a principal surface around the wells containing a substance capable of binding to a substance produced by the cells in the wells. A method for screening a target cell comprises: causing specimen cells and a cell culture broth to be contained in the wells of the microwell array; culturing the cells in a state permitting the diffusion of substances from the wells into the coating layer; feeding a label substance binding specifically to a substance produced by a target cell onto the coating layer; and detecting the substance produced by the target cell by the label substance binding around the well to specify the target cell.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: November 15, 2016
    Assignees: TOYAMA PREFECTURE, VALNEVA
    Inventors: Aishun Jin, Hiroyuki Kishi, Atsushi Muraguchi, Tsutomu Obata
  • Publication number: 20160312864
    Abstract: A hollow track body (21) has a plurality of rolling body traveling sections (22) formed in an outer surface of a hollow shaft in an axial direction and is supported by a support body (31) via a plurality of rolling bodies (40) that are rollable along the plurality of rolling body traveling sections (22), wherein a rack teeth array (25) in which roots of teeth penetrate into a hollow section (21h) of the hollow shaft are formed at arc-shaped sections (21a, 21b) formed between the plurality of rolling body traveling sections (22) in the axial direction.
    Type: Application
    Filed: December 4, 2014
    Publication date: October 27, 2016
    Applicant: THK CO., LTD.
    Inventors: Hiroyuki Kishi, Noritaka Suzuki, Eriko Watanabe
  • Publication number: 20160195131
    Abstract: The motion guide device includes a track member in which a rolling member rolling surface is formed along a longitudinal direction thereof, a movable member which is reciprocally movable with a number of rolling members being interposed therebetween and which is provided with a loaded rolling member rolling surface constituting a loaded rolling member rolling path opposing to the rolling member rolling surface and a rolling member return path, and a lid member provided with a pair of direction changing paths for connecting both end portions of the loaded rolling member rolling path and the rolling member return path to thereby constitute an endless circulation path. Flange portions are formed to both end portions of the movable member in the reciprocally moving direction by means of insert molding, and the flange portions are provided with fitting portions formed to end portion sides of the movable member.
    Type: Application
    Filed: August 25, 2014
    Publication date: July 7, 2016
    Applicant: THK CO., LTD.
    Inventors: Nobuyuki Ikegami, Fumiaki Morita, Yoshiaki Iwashige, Yasuhiro Suga, Mitsumasa Wada, Hiroyuki Kishi
  • Patent number: 9312729
    Abstract: A contactless power transfer core used for a power transmission coil or a power reception coil of a contactless power transfer apparatus includes: a winding core part wound by an electric wire; and a magnetic pole core part constituting a magnetic pole portion provided at both sides of the winding core part. A height of the uppermost part of a ferrite plate arranged on a face of the magnetic pole core part at a side opposing a counterpart coil is equal to or greater than a height of an outer circumference of the electric wire wound around the winding core part, and a height of the ferrite plate of a face at a side not opposing the counterpart coil is lower than the height of the outer circumference of the electric wire wound around the winding core.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: April 12, 2016
    Assignees: TECHNOVA INC., NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventors: Tomio Yasuda, Hiroyuki Kishi, Shigeru Abe, Akira Suzuki
  • Patent number: 9310362
    Abstract: A microwell array chip made of silicon and having multiple microwells where each microwell is used to store a single specimen organic cell. The microwell of the array chip is of a size and shape to hold just one organic cell and the interior surface of the microwells are coated with a fluorocarbon film.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: April 12, 2016
    Assignee: VALNEVA
    Inventors: Atsushi Muraguchi, Hiroyuki Kishi, Yoshiharu Tokimitsu, Sachiko Kondo, Tsutomu Obata, Satoshi Fujiki, Yoshiyuki Yokoyama, Hirofumi Nabesawa, Sotohiro Takabayashi, Katsumi Tanino
  • Publication number: 20150203886
    Abstract: An object is to provide a TCR closing system that enables not only bias-free analysis of TCR repertoires, but also collection of antigen-specific TCR ?/? cDNA pairs and evaluation of functions thereof. There is provided a method for producing a gene of T cell receptor (TCR) specific to an antigen A, which comprises 1) the step of stimulating a group of T cells including a T cell specific to an antigen A or one T cell specific to an antigen A under a condition effective for amplification of a TCR gene; 2) the step of identifying a T cell specific to an antigen A among the group of T cells including a T cell specific to the antigen A, and sorting one T cell specific to the antigen A into a vessel; and 3) the step of subjecting the one activated T cell specific to the antigen A in the vessel to PCR to amplify a gene of TCR specific to the antigen A.
    Type: Application
    Filed: July 24, 2013
    Publication date: July 23, 2015
    Inventors: Hiroyuki Kishi, Atsushi Muraguchi, Eiji Kobayashi, Tatsuhiko Ozawa
  • Publication number: 20150155094
    Abstract: A contactless power transfer transformer includes main body. The main body includes magnetic pole core members, winding wire core member, and wire. The winding wire core member is orthogonal to the magnetic pole core members and connects one portion of each of the pair of parallel magnetic pole core members with each other. The main body is fixed to fixing plate having a magnetic shield function and heat dissipation function. The connecting position of the winding wire core member with respect to the magnetic pole core members is located toward one side from a center in the longitudinal direction of the magnetic pole core members. At least a space between the pair of the magnetic coil core members each containing an end portion longer in distance to the connecting position is used as an arrangement space of component electrically connected to the electric wire.
    Type: Application
    Filed: May 21, 2013
    Publication date: June 4, 2015
    Applicant: TECHNOVA INC.
    Inventors: Tomio Yasuda, Hiroyuki Kishi, Isami Norigoe
  • Publication number: 20150123486
    Abstract: According to one embodiment, contactless power transfer transformer includes power transmission coil and power reception coil. At least one of the power transmission coil and the power reception coil is configured by coupled and both-sides wound coil. The coupled and both-sides wound coil is configured by both-sides wound coils. One of magnetic poles of one of the both-sides wound coils is connected to one of the magnetic poles of adjacent one of the both-sides wound coils. Directions of magnetic fluxes toward corresponding coil from each of the magnetic poles connected to each other are identical. The both-sides wound coils are selected so that leakage magnetic flux around moving body does not exceed predetermined value. Number of the both-sides wound coils is set so that value obtained by multiplying power transfer capacity of one of the both-sides wound coils by the number satisfies capacity of the transformer.
    Type: Application
    Filed: May 21, 2013
    Publication date: May 7, 2015
    Applicant: TECHNOVA INC.
    Inventors: Shigeru Abe, Yasuyoshi Kaneko, Tomio Yasuda, Hiroyuki Kishi
  • Patent number: 9021742
    Abstract: An opening and closing apparatus includes: a drive unit provided in an opening and closing body which is openably and closeably attached to a main body, and opening and closing the opening and closing body with respect to the main body by driving the opening and closing body using electric power; a secondary energy storage device provided in the opening and closing body and electrically connected to the drive unit in such a manner that the secondary energy storage device can be inductively charged and can supply electric power to the drive unit; and an electric power receiving coil provided in the opening and closing body so as to be capable of facing an electric power transmitting coil which is provided on the main body, and is electrically connected to a primary energy storage device installed on the main body, and electrically connected to the secondary energy storage device.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: May 5, 2015
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Kotaro Mizuma, Gang Xie, Takashi Nakamura, Seiichi Sumiya, Michihiro Asai, Tomio Yasuda, Kazuhiko Ida, Hiroyuki Kishi
  • Publication number: 20150038363
    Abstract: An object of the present invention is to stimulate a T cell without using a peptide/MHC tetramer. In the present invention, the step of supplying an antigen peptide to a T cell having a T cell receptor (TCR) that can recognize the antigen peptide on cell surface to form a complex of a major histocompatibility complex (MHC) molecule on the cell surface of the T cell and the antigen peptide is used, and the T cell is stimulated through recognition by TCR of the antigen peptide as the MHC molecule-antigen peptide complex on the cell surface of the same T cell. Such a stimulating and activating method would be applicable to not only T cells, but also various cells. According to the present invention, an antigen-specific T cell can be identified without establishing any antigen-specific T cell strain, and without using such a reagent as MHC/peptide tetramer. That is, a cancer-specific T cell can be efficiently and conveniently identified.
    Type: Application
    Filed: March 6, 2013
    Publication date: February 5, 2015
    Inventors: Hiroyuki Kishi, Atsushi Muraguchi, Hiroshi Hamana, Eiji Kobayashi, Tatsuhiko Ozawa
  • Publication number: 20140366450
    Abstract: An opening and closing apparatus includes: a drive unit provided in an opening and closing body which is openably and closeably attached to a main body, and opening and closing the opening and closing body with respect to the main body by driving the opening and closing body using electric power; a secondary energy storage device provided in the opening and closing body and electrically connected to the drive unit in such a manner that the secondary energy storage device can be inductively charged and can supply electric power to the drive unit; and an electric power receiving coil provided in the opening and closing body so as to be capable of facing an electric power transmitting coil which is provided on the main body, and is electrically connected to a primary energy storage device installed on the main body, and electrically connected to the secondary energy storage device.
    Type: Application
    Filed: June 12, 2014
    Publication date: December 18, 2014
    Applicant: AISIN SEIKI KABUSHIKI KAISHA
    Inventors: Kotaro MIZUMA, Gang Xie, Takashi Nakamura, Seiichi Sumiya, Michihiro Asai, Tomio Yasuda, Kazuhiko Ida, Hiroyuki Kishi