Patents by Inventor Hiroyuki Sawai
Hiroyuki Sawai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240390508Abstract: The present invention aims to provide a novel drug delivery system (DDS) technique capable of selectively delivering a drug (compound containing oligonucleotides for producing at least partially functional dystrophin protein) to muscle tissues such as cardiac muscle, skeletal muscle and the like and efficiently introducing the drug into the muscle cells. The present invention relates to a conjugate or a salt thereof including the following: (1) a peptide that binds to a transferrin receptor, and contains the amino acid sequence shown in SEQ ID NO: 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys); or an amino acid sequence resulting from substitution, deletion, addition, and/or insertion of not less than one and not more than 10 amino acid residues in the amino acid sequence shown in SEQ ID NO: 1, and (2) a compound comprising an oligonucleotide for producing an at least partially functional dystrophin protein.Type: ApplicationFiled: August 19, 2022Publication date: November 28, 2024Applicant: Takeda Pharmaceutical Company LimitedInventors: Takatoshi YOGO, Hideyuki SUGIYAMA, Kenichi MIYATA, Hiroyuki TAKADA, Masato YOSHIDA, Ryosuke TOKUNOH, Yasuo NAKAGAWA, Masato NIWA, Shigekazu SASAKI, Masaki OHUCHI, Naoki SAWAI, Masatoshi TAKUWA, Yujiro UCHINO, Yoko KANEMATSU, Koichiro FUKUDA, Takanori YOKOTO, Tetsuya NAGATA, Hiroki YAMADA
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Patent number: 12064972Abstract: A liquid container includes a storage portion configured to store the liquid and a connection member. The connection member is provided with a liquid outlet which is inserted with a liquid introduction portion, a container-side electrical connector which makes electrical contact with an apparatus-side electrical connection unit while receive at least +Z direction force from the apparatus-side electrical connection unit, a first receiver configured to receive a first positioning portion, a second receiver configured to receive a second positioning portion, and a recess which houses a protrusion of the case. The recess and the container-side electrical connector are formed at positions which at least partially overlap each other when viewed from a Z direction in a mounting state. In the mounting state, the width of the liquid container in the Z directions is larger than the width in the Y directions and the width in the X directions.Type: GrantFiled: May 4, 2023Date of Patent: August 20, 2024Assignee: SEIKO EPSON CORPORATIONInventors: Hiroyuki Kawate, Akihiro Toya, Yoshiaki Shimizu, Mikinori Sawai
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Patent number: 8379231Abstract: A display apparatus that has a display screen visible from a back face or a side face of an image forming apparatus is disposed on at least one side face of an image forming apparatus case.Type: GrantFiled: February 27, 2009Date of Patent: February 19, 2013Assignee: Sharp Kabushiki KaishaInventors: Yasuhiro Nakai, Satoshi Machino, Kenzoh Yoshida, Hiroyuki Sawai, Osamu Ueda
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Patent number: 8373867Abstract: A digital multifunction peripheral provided with a scanner portion, an operation portion, an image forming portion, a device control portion, a fax modem, a communications portion, a management portion, and a hard disk (HD) is connected to a server apparatus via an external network. A large-format display is attached integrally to a rear face of a case of the digital multifunction peripheral, with a first display screen facing toward the outside. The device control portion is connected to the server apparatus via the external network, and displays various pieces of provided information managed by the server apparatus on the first display screen.Type: GrantFiled: May 22, 2009Date of Patent: February 12, 2013Assignee: Sharp Kabushiki KaishaInventors: Yasuhiro Nakai, Satoshi Machino, Masanori Matsumoto, Tsutomu Yoshimoto, Hiroyuki Sawai, Osamu Ueda
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Publication number: 20090293020Abstract: A digital multifunction peripheral provided with a scanner portion, an operation portion, an image forming portion, a device control portion, a fax modem, a communications portion, a management portion, and a hard disk (HD) is connected to a server apparatus via an external network. A large-format display is attached integrally to a rear face of a case of the digital multifunction peripheral, with a first display screen facing toward the outside. The device control portion is connected to the server apparatus via the external network, and displays various pieces of provided information managed by the server apparatus on the first display screen.Type: ApplicationFiled: May 22, 2009Publication date: November 26, 2009Inventors: Yasuhiro NAKAI, Satoshi MACHINO, Masanori MATSUMOTO, Tsutomu YOSHIMOTO, Hiroyuki SAWAI, Osamu UEDA
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Publication number: 20090219588Abstract: In one embodiment of the present invention, a display apparatus that has a display screen visible from a back face or a side face of an image forming apparatus is disposed on at least one side face of an image forming apparatus case.Type: ApplicationFiled: February 27, 2009Publication date: September 3, 2009Inventors: Yasuhiro Nakai, Satoshi Machino, Kenzoh Yoshida, Hiroyuki Sawai, Osamu Ueda
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Patent number: 6785965Abstract: A caulked portion is formed by plastic deformation of a cylindrical portion which is formed at the inner end of a shaft member and is reduced in thickness toward the leading end in a diametrical outward direction. The force required to form the caulked portion is reduced, and the caulked portion is less susceptible to damage. Further, the force of the caulked portion for supporting the inner ring is ensured.Type: GrantFiled: April 2, 2003Date of Patent: September 7, 2004Assignee: NSK Ltd.Inventors: Hiroyuki Sawai, Takafumi Kuwano, Yoshifumi Hirano
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Patent number: 6761486Abstract: A bearing unit for vehicle wheel support comprising a shaft having a mounting flange for vehicle wheel or suspension apparatus, a step portion formed on one end portion thereof, a first inner ring raceway directly formed thereon, and a crimped portion formed on the end side of the step portion, and an inner ring fitted onto the step portion and having a second inner ring raceway thereon, the shaft being quench hardened at least at the first inner ring raceway with the crimped portion kept as formed and without quench hardened, and the inner ring being fixed to the shaft by the crimped portion of the shaft.Type: GrantFiled: January 14, 2003Date of Patent: July 13, 2004Assignee: NSK Ltd.Inventors: Hiroya Miyazaki, Yoshihisa Ohnuki, Takafumi Kuwano, Hiroyuki Sawai, Hideo Ouchi
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Patent number: 6672770Abstract: A bearing unit for vehicle wheel support comprising a shaft having a mounting flange for vehicle wheel or suspension apparatus, a step portion formed on one end portion thereof, a first inner ring raceway directly formed thereon, and a crimped portion formed on the end side of the step portion, and an inner ring fitted onto the step portion and having a second inner ring raceway thereon, the shaft being quench hardened at least at the first inner ring raceway with the crimped portion kept as formed and without quench hardened, and the inner ring being fixed to the shaft by the crimped portion of the shaft.Type: GrantFiled: April 1, 2002Date of Patent: January 6, 2004Assignee: NSK Ltd.Inventors: Hiroya Miyazaki, Yoshihisa Ohnuki, Takafumi Kuwano, Hiroyuki Sawai, Hideo Ouchi
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Publication number: 20030200658Abstract: A caulked portion is formed by plastic deformation of a cylindrical portion which is formed at the inner end of a shaft member and is reduced in thickness toward the leading end in a diametrical outward direction. The force required to form the caulked portion is reduced, and the caulked portion is less susceptible to damage. Further, the force of the caulked portion for supporting the inner ring is ensured.Type: ApplicationFiled: April 2, 2003Publication date: October 30, 2003Applicant: NSK LTD.Inventors: Hiroyuki Sawai, Takafumi Kuwano, Yoshifumi Hirano
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Patent number: 6581287Abstract: A caulked portion is formed by plastic deformation of a cylindrical portion which is formed at the inner end of a shaft member and is reduced in thickness toward the leading end in a diametrical outward direction. The force required to form the caulked portion is reduced, and the caulked portion is less susceptible to damage. Further, the force of the caulked portion for supporting the inner ring is ensured.Type: GrantFiled: September 7, 2001Date of Patent: June 24, 2003Assignee: NSK Ltd.Inventors: Hiroyuki Sawai, Takafumi Kuwano, Yoshifumi Hirano
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Publication number: 20030103705Abstract: A bearing unit for vehicle wheel support comprising a shaft having a mounting flange for vehicle wheel or suspension apparatus, a step portion formed on one end portion thereof, a first inner ring raceway directly formed thereon, and a crimped portion formed on the end side of the step portion, and an inner ring fitted onto the step portion and having a second inner ring raceway thereon, the shaft being quench hardened at least at the first inner ring raceway with the crimped portion kept as formed and without quench hardened, and the inner ring being fixed to the shaft by the crimped portion of the shaft.Type: ApplicationFiled: January 14, 2003Publication date: June 5, 2003Inventors: Hiroya Miyazaki, Yoshihisa Ohnuki, Takafumi Kuwano, Hiroyuki Sawai, Hideo Ouchi
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Patent number: 6538348Abstract: In a state that a wafer stage is not positioned in the center of the Y-direction traveling range, thrusts Fa, Fb supplied from a pair of linear motors to a Y-direction stage are made different and the Y-direction stage is moved in the X direction so that moments Ma, Mb about the centroid of the Y-direction stage by the thrusts Fa, Fb cancel each other. Since the moments Ma, Mb about the centroid generated by the thrusts cancel each other and the thrusts do not act as forces for rotating the Y-direction stage, the Y-direction stage is not deflected in a yawing direction. Such a stage device as constructed above can prevent deflection in a yawing direction due to displacement of the centroid position of an object to be positioned or a stage and precisely move the object to be positioned to a target position.Type: GrantFiled: February 21, 2001Date of Patent: March 25, 2003Assignee: Sharp Kabushiki KaishaInventors: Hiroyuki Sawai, Hiroshi Ishii
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Patent number: 6524011Abstract: A bearing unit for vehicle wheel support comprising a shaft having a mounting flange for vehicle wheel or suspension apparatus, a step portion formed on one end portion thereof, a first inner ring raceway directly formed thereon, and a crimped portion formed on the end side of the step portion, and an inner ring fitted onto the step portion and having a second inner ring raceway thereon, the shaft being quench hardened at least at the first inner ring raceway with the crimped portion kept as formed and without quench hardened, and the inner ring being fixed to the shaft by the crimped portion of the shaft.Type: GrantFiled: July 27, 2001Date of Patent: February 25, 2003Assignee: NSK Ltd.Inventors: Hiroya Miyazaki, Yoshihisa Ohnuki, Takafumi Kuwano, Hiroyuki Sawai, Hideo Ouchi
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Publication number: 20020146185Abstract: A bearing unit for vehicle wheel support comprising a shaft having a mounting flange for vehicle wheel or suspension apparatus, a step portion formed on one end portion thereof, a first inner ring raceway directly formed thereon, and a crimped portion formed on the end side of the step portion, and an inner ring fitted onto the step portion and having a second inner ring raceway thereon, the shaft being quench hardened at least at the first inner ring raceway with the crimped portion kept as formed and without quench hardened, and the inner ring being fixed to the shaft by the crimped portion of the shaft.Type: ApplicationFiled: April 1, 2002Publication date: October 10, 2002Inventors: Hiroya Miyazaki, Yoshihisa Ohnuki, Takafumi Kuwano, Hiroyuki Sawai, Hideo Ouchi
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Patent number: 6434988Abstract: A tool controlling apparatus includes a position controlling unit and a torque controlling unit for carrying out the conversion between the position control and the torque control of the tool for pushing the work, and the conversion of the torque in the torque control in a moment by using a servo motor in the course of process of the work.Type: GrantFiled: March 1, 2001Date of Patent: August 20, 2002Assignee: NSK, Ltd.Inventors: Ryoichi Suzuki, Takeharu Hamade, Hiroyuki Sawai
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Patent number: 6428143Abstract: To provide an ink jet image forming method and an ink jet image forming device capable of forming an image of superior quality by using quickly drying ink and slowly drying ink in combination, wherein deviation which may occur in a discharge position of ink causes no reduction in the resolution of the image, black ink is adopted as the slowly drying ink, and so is white ink as one of the quickly drying ink. A white dot is formed with the white ink in a position to form a black dot on white recording paper, thereafter applying the black ink thereto. Deviation which may occur in the discharge position of the quickly drying white ink on the recording paper thus becomes almost visually unnoticeable.Type: GrantFiled: March 7, 2001Date of Patent: August 6, 2002Assignee: Sharp Kabushiki KaishaInventors: Kouichi Irihara, Hiroyuki Sawai
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Patent number: 6425182Abstract: A roller cage made of metal for holding rollers of a roller bearing, includes: separation bars separately defining a plurality of window holes along a peripheral direction of the bearing with a constant interval thereamong. The window holes respectively receive said rollers therein. Each of the separation bars includes: a contact surface being formed by press-molding one of an outer diameter surface side end portion and an inner diameter surface side end portion thereof, and contacting with the rolling surface of the roller; and an expansion portion expanding to a radial direction of the bearing at the other of the outer diameter surface side end portion and the inner diameter surface side end portion which is not subjected to the press-molding.Type: GrantFiled: November 15, 2000Date of Patent: July 30, 2002Assignee: NSK Ltd.Inventors: Akiyoshi Honda, Masahide Matsubara, Kunio Fukuda, Hiroyuki Sawai, Toshiyuki Suzuki, Akiyoshi Yamaguchi
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Patent number: 6422758Abstract: A bearing unit for vehicle wheel support comprising a shaft having a mounting flange for vehicle wheel or suspension apparatus, a step portion formed on one end portion thereof, a first inner ring raceway directly formed thereon, and a crimped portion formed on the end side of the step portion, and an inner ring fitted onto the step portion and having a second inner ring raceway thereon, the shaft being quench hardened at least at the first inner ring raceway with the crimped portion kept as formed and without quench hardened, and the inner ring being fixed to the shaft by the crimped portion of the shaft.Type: GrantFiled: August 18, 2000Date of Patent: July 23, 2002Assignee: NSK Ltd.Inventors: Hiroya Miyazaki, Yoshihisa Ohnuki, Takafumi Kuwano, Hiroyuki Sawai
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Publication number: 20020006240Abstract: A caulked portion is formed by plastic deformation of a cylindrical portion which is formed at the inner end of a shaft member and is reduced in thickness toward the leading end in a diametrical outward direction. The force required to form the caulked portion is reduced, and the caulked portion is less susceptible to damage. Further, the force of the caulked portion for supporting the inner ring is ensured.Type: ApplicationFiled: September 7, 2001Publication date: January 17, 2002Applicant: NSK LTD.Inventors: Hiroyuki Sawai, Takafumi Kuwano, Yoshifumi Hirano