Patents by Inventor Hisahiro Tabuchi

Hisahiro Tabuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding hamster 1GF-1 proteins and methods thereof
    Patent number: 8062863
    Abstract: A polypeptide selected from the group consisting of: (1) a polypeptide having the amino acid sequence of SEQ ID NO: 1, and (2) a polypeptide having an amino acid sequence in which the third amino acid of the amino acid sequence of SEQ ID NO: 1 is substituted by another amino acid and having insulin-like growth factor 1 (IGF-1) activity; a DNA encoding said polypeptide; a vector containing said DNA; a host cell containing said vector; and a method for preparing a recombinant protein using said polypeptide.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: November 22, 2011
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hisahiro Tabuchi, Saeko Tanaka
  • CELL FOR USE IN PROUDUCTION OF HETEROPROTEINS AND PRODUCTION METHOD USING THE SAME
    Publication number: 20110014654
    Abstract: The present invention provides a method capable of producing a protein efficiently. A method of producing a polypeptide, comprising culturing a cell which strongly expresses a bicarbonate transporter and has a transferred DNA encoding a desired polypeptide and thereby allowing the cell to produce said polypeptide.
    Type: Application
    Filed: October 23, 2008
    Publication date: January 20, 2011
    Inventors: Hisahiro Tabuchi, Satoshi Tainaka, Tomoya Sugiyama
  • METHOD FOR PRODUCING A CELL CAPABLE OF HIGH-YIELD PRODUCTION OF HETEROPROTEINS
    Publication number: 20110003334
    Abstract: The present invention provides a cell capable of high-yield production of polypeptides and a method for producing the same. The present invention relates to a method for producing a cell capable of high-yield production of a desired polypeptide, wherein a strongly taurine transporter-expressing cell into which DNA encoding the desired polypeptide has been introduced is cultured in the presence of a high concentration of methotrexate and a cell capable of high-yield production of the desired polypeptide is selected from among surviving cells.
    Type: Application
    Filed: October 14, 2008
    Publication date: January 6, 2011
    Inventors: Hisahiro Tabuchi, Tomoya Sugiyama
  • METHOD FOR PRODUCTION OF POLYPEPTIDE
    Publication number: 20100233759
    Abstract: The present invention provides a method capable of producing a natural or recombinant protein in high yield. The present invention relates to a method of producing a polypeptide, comprising culturing a cell which strongly expresses cysteine sulfinic acid decarboxylase and has a transferred DNA encoding a desired polypeptide and thereby allowing the cell to produce the polypeptide. Hamster cysteine sulfinic acid decarboxylase, a DNA encoding the same, a recombinant vector and a transformed cell are also provided.
    Type: Application
    Filed: March 13, 2008
    Publication date: September 16, 2010
    Inventors: Hisahiro Tabuchi, Satoshi Tainaka, Tomoya Sugiyama
  • METHOD OF PRODUCING HETEROGENEOUS PROTEIN
    Publication number: 20100167346
    Abstract: The present invention provides a method capable of producing a natural or recombinant protein in high yield. The present invention relates to a method of producing a polypeptide, comprising culturing a cell which strongly expresses alanine aminotransferase and has a transferred DNA encoding a desired polypeptide and thereby allowing the cell to produce the polypeptide.
    Type: Application
    Filed: August 6, 2008
    Publication date: July 1, 2010
    Inventors: Hisahiro Tabuchi, Tomoya Sugiyama
  • Taurine Transporter Gene
    Publication number: 20090191591
    Abstract: The present invention provides a method capable of producing a natural or recombinant protein at low cost. The present invention relates to a method of producing a polypeptide, comprising culturing a cell which strongly expresses a taurine transporter and has a transferred DNA encoding a desired polypeptide and thereby allowing the cell to produce the polypeptide. Hamster taurine transporter, a DNA encoding the same, a recombinant vector and a transformed cell are also provided.
    Type: Application
    Filed: April 12, 2007
    Publication date: July 30, 2009
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Hisahiro Tabuchi, Tomoya Sugiyama, Saeko Tanaka, Satoshi Tainaka
  • Methods for Producing Proteins Using Hamster Igf-1
    Publication number: 20090011453
    Abstract: A polypeptide selected from the group consisting of: (1) a polypeptide having the amino acid sequence of SEQ ID NO: 1, and (2) a polypeptide having an amino acid sequence in which the third amino acid of the amino acid sequence of SEQ ID NO: 1 is substituted by another amino acid and having insulin-like growth factor 1 (IGF-1) activity; a DNA encoding said polypeptide; a vector containing said DNA; a host cell containing said vector; and a method for preparing a recombinant protein using said polypeptide.
    Type: Application
    Filed: February 21, 2006
    Publication date: January 8, 2009
    Inventors: Hisahiro Tabuchi, Saeko Tanaka