Abstract: A method of producing a polypeptide compound, wherein a peptide compound represented by formula (P) is obtained by inducing an amide formation reaction between an amino-protected lactam compound represented by formula (R1) and an amino acid ester or peptide ester compound represented by formula (R2). The definitions for the reference signs in formulae (R1), (R2), and (P) are as set forth in the claims.

Abstract: When the duty command value is less than or equal to a threshold value, the motor control device performs the complementary PWM control, and when the duty command value is greater than the threshold value, it sets, for the first element, a first period in which the first element remains turned on and a second period in which control is performed with a corrected duty cycle to turn off the first element for a longer period, and performs average PWM control of which average duty cycle in a total period of the first and second periods is same as a set duty cycle. The motor control device turns on the second element while the first element is turned off in the second period.

Abstract: The present invention provides a catalyst containing a Brønsted acid as a novel means capable of producing an amide compound by highly stereoselectively and/or highly efficiently causing an amidation reaction in a variety of substrates having a carboxylic ester group and an amino group.

Abstract: [Problem] To provide a novel means capable of generating highly stereoselective and/or highly efficient amidation reactions in a variety of substrates having a carboxyl group and an amino group, and capable of producing amide compounds. [Solution] A reaction agent for amide reactions between carboxyl groups and amino groups and including a silane compound indicated by general formula (A) and/or general formula (B). (In general formulas (A) and (B), each substituent represents the definition described in the Claims.

Abstract: Provided is a novel method whereby an amide compound can be produced by highly stereoselectively and efficiently performing amidation between a plurality of amino acids and/or peptides. A compound of general formula (3) is synthesized by forming an amide bond between the carboxyl group on the right side of general formula (1) in a compound represented thereby and the amino group on the left side of general formula (2) in a compound represented thereby, in the presence of a Lewis acid catalyst and a silylating agent [in formulae (1), (2) and (3), each symbol has the same meaning as defined in claims].

Abstract: When the duty command value is less than or equal to a threshold value, the motor control device performs the complementary PWM control, and when the duty command value is greater than the threshold value, it sets, for the first element, a first period in which the first element remains turned on and a second period in which control is performed with a corrected duty cycle to turn off the first element for a longer period, and performs average PWM control of which average duty cycle in a total period of the first and second periods is same as a set duty cycle. The motor control device turns on the second element while the first element is turned off in the second period.

Abstract: A housing is shaped in a bottomed tubular form. A stator is fixed to a stator receiving portion of a tubular portion of the housing at an arbitrary angle position around an axis of the tubular portion. A heat sink is fixed to a heat sink fixing portion of the tubular portion at an arbitrary angle position around the axis of the tubular portion. A control device includes a connector for electrically connecting with an external device and is configured to control energization of the stator. Each of a plurality of externally mounting portions is a part of a bottom portion of the housing and is formed integrally with the housing in one-piece. A plurality of housing positioning holes are formed at the bottom portion of the housing and are arranged at equal intervals along a circle that is concentric with the tubular portion.

Abstract: Provided is a novel method for producing amide compounds at high stereochemical selectivities. The method according to the present invention for producing amide compounds is provided with an amidation step for reacting, in the presence of a catalyst comprising a metal compound, an amino compound with an aminoester compound represented by general formula (1) to amidate the ester group in the aminoester compound.

Abstract: A coffee bean grinder 1 has a hopper 2 into which coffee beans are inserted. The grinding unit 3 grinds coffee beans supplied from the hopper 2. The discharge unit 4 discharges coffee beans ground by the grinding unit 3. The mounting unit 5 mounts a portafilter 6 to be closely pressed against the bottom end of the discharge unit 4. The discharge unit 4 has a guide path 41 facing vertically downward, and a tapered section 42 in which the inner diameter increases towards the bottom. A sloped section 502 of a close-fitting member 50b, attached to the bottom end portion of the tapered section 42, is closely pressed against a top surface 63a of the filter basket 63 of the portafilter 6. The tapered section 42 has a hole 44 for allowing air in the airtight space to escape, thereby allowing the coffee beans to fall.

Abstract: Provided is a novel method whereby an amide compound can be produced by highly stereoselectively and efficiently performing amidation between a plurality of amino acids and/or peptides.

Abstract: Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal of the group 4 or group 5 in the periodic table, reacting at least one kind of hydroxy ester compound selected from the group consisting of an ?-hydroxy ester compound, a ?-hydroxy ester compound, a ?-hydroxy ester compound and a ?-hydroxy ester compound with an amino compound so as to amidate an ester group having a hydroxyl group at the ?-, ?-, ?- or ?-position of the hydroxy ester compound.

Abstract: A sensor sheet is manufactured by forming a conductive heat-sensitive material 5 over first wiring electrodes 3a and forming second wiring electrodes 4a over the conductive heat-sensitive material 5. For this reason, no adhesion surface (boundary surface), which is formed when adhesion is performed later, exists between the first wiring electrode 3a and the conductive heat-sensitive material 5 and between the conductive heat-sensitive material 5 and the second wiring electrodes 4a.

Abstract: Provided is a novel method for producing amide compounds at high stereochemical selectivities. The method according to the present invention for producing amide compounds is provided with an amidation step for reacting, in the presence of a catalyst comprising a metal compound, an amino compound with an aminoester compound represented by general formula (1) to amidate the ester group in the aminoester compound.

Abstract: A sensor sheet is manufactured by forming a conductive heat-sensitive material 5 over first wiring electrodes 3a and forming second wiring electrodes 4a over the conductive heat-sensitive material 5. For this reason, no adhesion surface (boundary surface), which is formed when adhesion is performed later, exists between the first wiring electrode 3a and the conductive heat-sensitive material 5 and between the conductive heat-sensitive material 5 and the second wiring electrodes 4a.

Abstract: A pressure measurement device includes a platen, a pressure sensor, a signal acquisition section, and a data processing section. The pressure sensor includes a plurality of pressure-sensitive points arranged on the platen. The signal acquisition section is configured to acquire measurement data that is obtained when a measurement object in contact with a surface of the platen passes over the pressure sensor a plurality of times. The measurement object moves relative to the platen and along a circular orbit on the platen. The data processing section is configured to calculate periods in each of which the measurement object passes over the pressure sensor and to acquire period data for each of the periods from the measurement data.

Abstract: A pressure measurement device includes a platen, a pressure sensor, a signal acquisition section, and a data processing section. The pressure sensor includes a plurality of pressure-sensitive points arranged on the platen. The signal acquisition section is configured to acquire measurement data that is obtained when a measurement object in contact with a surface of the platen passes over the pressure sensor a plurality of times. The measurement object moves relative to the platen and along a circular orbit on the platen. The data processing section is configured to calculate periods in each of which the measurement object passes over the pressure sensor and to acquire period data for each of the periods from the measurement data.

Abstract: A damper apparatus includes a piston having a flange-shaped piston main body and piston rods which project from both ends of the piston main body, a cylinder having a cylinder main body which accommodates the piston main body slidably and cylindrical portions which support slidably the piston rods, respectively, a fastener which is attached to the one cylindrical portion so as to secure the cylinder to an opening/closing member, and a coil spring which biases the one piston rod to project from the other cylindrical portion such that a distal end portion of the piston rod abuts a circumferential edge of an opening portion of a vehicle.