Abstract: A support carrying an immobilized selective binding substance, that the support surface has a polymer containing the structural unit represented by the following General Formula (1) in an amount of 10% or more with respect all monomer units, and a selective binding substance is immobilized on the support surface by binding to the carboxyl group formed thereon via a covalent bond: (in General Formula (1), R1, R2, and R3 each represent an alkyl or aryl group or a hydrogen atom.

Abstract: A support carrying an immobilized selective binding substance, that the support surface has a polymer containing the structural unit represented by the following General Formula (1) in an amount of 10% or more with respect all monomer units, and a selective binding substance is immobilized on the support surface by binding to the carboxyl group formed thereon via a covalent bond: (in General Formula (1), R1, R2, and R3 each represent an alkyl or aryl group or a hydrogen atom.

Abstract: This invention relates to a composition, kit, DNA chip, and use thereof for detecting, diagnosing, and predicting metastasis of kidney cancer and/or for predicting the prognosis for kidney cancer, comprising one or a plurality of polynucleotides selected from the group consisting of polynucleotides, mutants thereof or fragments thereof, the expression levels of which vary in kidney cancer cells from a patient with a poor prognosis when compared with that in kidney cancer cells from a patient with a good prognosis; or antibodies or fragments thereof that bind specifically to polypeptides, mutants thereof or fragments thereof, the expression levels of which vary in the similar manner.

Abstract: This invention is directed to an analysis chip comprising a substrate having a surface on which a selective binding substance is immobilized; a cover member adhered to the substrate; and particles movably contained or injected in a void between the substrate and the cover member; wherein the surfaces of the particles are coated with a surfactant. By this invention, generation of bubbles which inhibit the selective reaction between the test substance and the immobilized selective binding substance is suppressed, thereby reducing the deviation of data, suppressing the lowering of sensitivity, and promoting the reproducibility of the measurement.

Abstract: This invention relates to a method for detecting in vitro a urothelial cancer, comprising measuring CXCL1 protein, or expression of a gene encoding the protein, in a biological sample from a subject, and to a kit for diagnosing a urothelial cancer comprising an antibody or nucleic acid probe, which is capable of binding specifically to the CXCL1 protein or a gene encoding the protein, respectively.

Abstract: A lab-on-chip substrate includes a resin having a silicon content of 10% or less by weight as its base material and a hydrophilic polymer covalently bound onto the surface thereof by high-energy ray irradiation suitable for a protein-processing chip. The lab-on-chip substrate is resistant to washing and usable for an extended period of time without adsorption of proteins on the base material surface, i.e., a protein electrophoretic polymeric chip having a microchannel allowing high-accuracy analysis of trace amounts of proteins because of reduction in the amount of detection noise.

Abstract: This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same.

Abstract: A dielectric paste of the present invention contains a binder resin, a cross-linking agent, a thermal polymerization initiator, and an inorganic powder, wherein the content of the thermal polymerization initiator is 3 to 30 parts by weight to 100 parts by weight of the total of the binder resin and the cross-linking agent. A method of manufacturing a plasma display, of the present invention, includes a first step of forming electrode patterns using an electrode paste, a second step of forming a dielectric paste coating film using a dielectric paste, a third step of forming barrier rib patterns using a barrier rib paste, a subsequent step of simultaneously firing at least the electrode patterns, the dielectric paste coating film, and the barrier rib patterns, and a step of performing curing after the second step.

Abstract: This invention relates to a hollow-nanoparticle-based biosensing tool, which comprises proteins capable of forming nanoparticles through the incorporation of a lipid bilayer and specific biorecognition molecules bound thereto and a biosensing method using such tool.

Abstract: The present invention relates to a lab-on-chip substrate, comprising a resin having a silicon content of 10% or less by weight as its base material and a hydrophilic polymer covalently bound onto the surface thereof by high-energy ray irradiation, and in particular, to a protein-processing chip. The present invention provides a lab-on-chip substrate resistant to washing and usable for an extended period of time without adsorption of proteins on the base material surface, i.e., a protein electrophoretic polymeric chip having a microchannel allowing high-accuracy analysis of trace amounts of proteins because of reduction in the amount of detection noise.

Abstract: The method of stirring a solution according to the present invention is a method of stirring a solution comprising contacting a selective binding substance immobilized on the surface of a carrier with a solution containing an analyte substance reactive with the selective binding substance, and mixing the fine particles or air bubbles into the solution containing an analyte substance, and moving the fine particles or air bubbles without allowing contact thereof with the selective binding substance-immobilized surface. The present invention provides a stirring method that accelerates the reaction of a carrier-immobilized selective binding substance with an analyte substance and detects a trace amount of analyte at high signal intensity and high S/N ratio. The present invention enables diagnosis and examination in the clinical setting by using a selective binding substance-immobilized carrier such as DNA chip.

Abstract: A support carrying an immobilized selective binding substance, that the support surface has a polymer containing the structural unit represented by the following General Formula (1) in an amount of 10% or more with respect all monomer units, and a selective binding substance is immobilized on the support surface by binding to the carboxyl group formed thereon via a covalent bond: (in General Formula (1), R1, R2, and R3 each represent an alkyl or aryl group or a hydrogen atom.

Abstract: A dielectric paste of the present invention contains a binder resin, a cross-linking agent, a thermal polymerization initiator, and an inorganic powder, wherein the content of the thermal polymerization initiator is 3 to 30 parts by weight to 100 parts by weight of the total of the binder resin and the cross-linking agent. A method of manufacturing a plasma display, of the present invention, includes a first step of forming electrode patterns using an electrode paste, a second step of forming a dielectric paste coating film using a dielectric paste, a third step of forming barrier rib patterns using a barrier rib paste, a subsequent step of simultaneously firing at least the electrode patterns, the dielectric paste coating film, and the barrier rib patterns, and a step of performing curing after the second step.

Abstract: A dielectric paste of the present invention contains a binder resin, a cross-linking agent, a thermal polymerization initiator, and an inorganic powder, wherein the content of the thermal polymerization initiator is 3 to 30 parts by weight to 100 parts by weight of the total of the binder resin and the cross-linking agent. A method of manufacturing a plasma display, of the present invention, includes a first step of forming electrode patterns using an electrode paste, a second step of forming a dielectric paste coating film using a dielectric paste, a third step of forming barrier rib patterns using a barrier rib paste, a subsequent step of simultaneously firing at least the electrode patterns, the dielectric paste coating film, and the barrier rib patterns, and a step of performing curing after the second step.

Abstract: Disclosed is an array immobilizing selective binding substances thereon, with which each sample can be distinguished without relying on the positions, an arbitrary array may be made, the density may be freely changed depending on the method of using, and with which the reaction between the bound sample and another sample can be detected easily. The present invention provides a fiber on which a selective-binding substance is immobilized, or a fiber array comprising a bundle of the fibers. A method for binding reaction between a selective binding substance and a corresponding selective binding substance, in which a test sample and/or the corresponding selective binding substance is(are) moved relative to the surface on which the selective binding substance is immobilized by, for example, applying an AC voltage in a direction crossing the perpendicular axis of the surface on which the selective binding substance is immobilized was also provided.

Abstract: A dielectric paste of the present invention contains a binder resin, a cross-linking agent, a thermal polymerization initiator, and an inorganic powder, wherein the content of the thermal polymerization initiator is 3 to 30 parts by weight to 100 parts by weight of the total of the binder resin and the cross-linking agent. A method of manufacturing a plasma display, of the present invention, includes a first step of forming electrode patterns using an electrode paste, a second step of forming a dielectric paste coating film using a dielectric paste, a third step of forming barrier rib patterns using a barrier rib paste, a subsequent step of simultaneously firing at least the electrode patterns, the dielectric paste coating film, and the barrier rib patterns, and a step of performing curing after the second step.

Abstract: Phase-change type rewritable optical recording media, such as optical discs, optical cards, and optical tapes, where recorded data can be erased or overwritten and where data can be recorded with high speed and high density by applying a light beam can include an optical recording medium is one that includes a laminate member, which in various embodiments contains a transparent substrate, a first dielectric layer, a recording layer, a second dielectric layer, a light absorbing layer, and/or a reflecting layer. In various embodiments of the invention, the shortest distance between recorded marks in the recording direction along the track is less than &lgr;/NA, with &lgr; and NA denoting the wavelength of the light used and the numerical aperture of the objective lens of the optical head, respectively.

Abstract: An optical recording medium has a high hardness layer, first dielectric layer, recording layer, second dielectric layer and reflective layer. The hardness of the high hardness layer is larger than the hardness of the first dielectric layer, and the thickness of the second dielectric layer is in the range of 3 to 50 nm. Such a rewritable phase change type optical recording medium may show reduced degradation in the write-start portion and write-end portion of frequently rewritten sectors, and have good jitter characteristics.

Abstract: An optical recording medium having each of a land and a groove and comprises at least a recording layer, dielectric layers and reflection layer. Recording and erasing of data can be carried out on both land and groove by a phase change between amorphous and crystalline states. The mirror portion may have reflectance characteristics selected from at least one of a reflectance of more than 15% and no more than 35%, when in a crystalline state, and 10% or less, when in an amorphous state. Alternatively, additionally, the depth of the groove may be such as to form an optical path length equal to 1/7 to 1/5 of the wavelength of the reproducing light and the photo-absorbance of the recording layer in the amorphous phase and the photo-absorbance in the crystalline phase may satisfy the following formula, Aa-Ac.ltoreq.10 where Aa is the photo-absorbance (%) of the recording layer in the amorphous phase and Ac is the photo-absorbance (%) of the recording layer in the crystalline phase.

Abstract: An optical recording medium having each of a land and a groove and comprises at least a recording layer, dielectric layers and reflection layer. Recording and erasing of data can be carried out on both land and groove by a phase change between amorphous and crystalline states. The mirror portion may have reflectance characteristics selected from at least one of a reflectance of more than 15% and no more than 35%, when in a crystalline state, and 10% or less, when in an amorphous state. Alternatively, additionally, the depth of the groove may be such as form an optical path length equal to 1/7 to 1/5 of the wavelength of the reproducing light and the photo-absorbance of the recording layer in the amorphous phase and the photo-absorbance in the crystalline phase may satisfy the following formula,Aa-Ac.ltoreq.10where Aa is the photo-absorbance (%) of the recording layer in the amorphous phase and Ac is the photo-absorbance (%) of the recording layer in the crystalline phase.