Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.

Abstract: A semiconductor may include an active region, an epitaxial source/drain formed in and extending above the active region, and a first dielectric layer formed over a portion of the active region. The semiconductor may include a first metal gate and a second metal gate formed in the first dielectric layer, a second dielectric layer formed over the first dielectric layer and the second metal gate, and a titanium layer, without an intervening fluorine residual layer, formed on the metal gate and the epitaxial source/drain. The semiconductor may include a first metal layer formed on top of the titanium on the first metal gate, a second metal layer formed on top of the titanium layer on the epitaxial source/drain, and a third dielectric layer formed on the second dielectric layer. The semiconductor may include first and second vias formed in the third dielectric layer.

Abstract: This disclosure relates to a composition that includes at least one first ruthenium removal rate enhancer; at least one copper removal rate inhibitor; at least one low-k removal rate inhibitor; and an aqueous solvent.

Abstract: This disclosure discloses an optical sensing device. The device includes a carrier body; a first light-emitting device disposed on the carrier body; and a light-receiving device including a group III-V semiconductor material disposed on the carrier body, including a light-receiving surface having an area, wherein the light-receiving device is capable of receiving a first received wavelength having a largest external quantum efficiency so the ratio of the largest external quantum efficiency to the area is ?13.

Abstract: There is provided a textile including a strain sensing portion integrally knitted therein and including groups of courses of yarn, each group including a first course of conductive yarn, a second course of dielectric yarn, and a third course of conductive yarn, each course including a plurality of knitted loops. The second course is arranged in between the first and third courses and configured to have a higher elasticity than the first and third courses such that when the strain sensing portion is at a relaxed state, corresponding knitted loops of the first and third courses are caused by a corresponding knitted loop of the second course to contact each other, and when the strain sensing portion is at a stretched state, corresponding knitted loops of the first and third courses are caused by a corresponding knitted loop of the second course to be not in contact with each other.

Abstract: The present invention provides a joint optimization method and system for delay and spectrum occupation in a cloud-edge collaborative network. The method includes: initializing a cloud-edge collaborative network, and generating a set of user requests; establishing a target function of minimum average end-to-end delay and minimum spectrum slot occupation of a user request; during processing of each user request based on the target function, sequentially determining whether a node and path selection uniqueness constraint, a mobile edge computing (MEC) server load constraint, a spectrum resource occupation and uniqueness constraint, a spectrum continuity constraint, and a spectrum consistency constraint are satisfied, where if all constraints are satisfied, the user request is successfully processed, and the process turns to step S4; or if any constraint is not satisfied, the user request fails to be processed; and calculating average end-to-end delay and spectrum resource occupancy of the user request.

Abstract: An interaction method and apparatus and an electronic device. The method comprises: displaying a first application interface, wherein the first application interface comprises an interface of a first application; and creating a second application account in the first application interface, wherein the second application account is used for logging in a second application. Therefore, a new interaction mode is provided.

Abstract: A system and a method for parameter optimization with adaptive search space and a user interface using the same are provided. The system includes a data acquisition unit, an adaptive adjustment unit and an optimization search unit. The data acquisition unit obtains a set of executed values of several operating parameters and a target parameter. The adaptive adjustment unit includes a parameter space transformer and a search range definer. The parameter space transformer performs a space transformation on a parameter space of the operating parameters according to the executed values. The search range definer defines a parameter search range in a transformed parameter space based on the sets of the executed values. The optimization search unit takes the parameter search range as a limiting condition and takes optimizing the target parameter as a target to search for a set of recommended values of the operating parameters.

Abstract: Systems and methods for automated first arrival picking are disclosed. The method includes obtaining a seismic dataset composed of a plurality of seismic gathers and determining a pilot for each gather, where the pilot includes a position on an ordinate axis for each seismic trace representing a first arrival. The method continues iteratively until a stopping criterion is met by creating a preconditioned gather using the pilot, determining a differential pilot using global path tracing subject to a constraint and incrementing the pilot using the differential pilot to create a total picked first arrival. Once the stopping criterion has been met, the method further includes determining a final picked first arrival based on the total picked first arrival, determining a seismic velocity model from the final picked first arrival using a tomographic inversion and creating a seismic image using the seismic velocity model and the seismic dataset.

Abstract: Embodiments of the invention are directed to computer-implemented methods of analyzing a web-based software application. A non-limiting example of the computer implemented method includes generating, using a processor system, a set of to-be-tested element-event pairs of the web-based software application. A set of compatibility tests is received at the processor system, where the set of compatibility tests is operable to perform compatibility testing of a corresponding set of element-event pairs. A comparison is performed between the set of to-be-tested element-event pairs and the corresponding set of element-event pairs. A compatibility testing recommendation is generated based at least in part on a result of the comparison.

Abstract: The present invention provides a speed measurement method and apparatus using a plurality of cameras. The speed measurement method includes: S1: calibrating positions of the respective cameras in a camera group, which are on a mobile platform at fixed relative positions; S2: obtaining a sequence of synchronized images from the respective cameras in the camera group, and recording time stamps thereof; and S3: performing a registration on the images captured by the respective cameras in the camera group and, if a registration result of two of the images is greater than a first threshold, calculating a position transformation matrix for the two images, and then calculating a position transformation matrix for the mobile platform based on the positional relationships between the cameras that captured the two images, and finally calculating a speed information of the mobile platform based on the position transformation matrix and an interval between times when the two images were captured.

Abstract: Provided herein are methods of treating eye disorders by administering an anti-VEGF antibody and/or conjugate to a subject having an eye disorder. The anti-VEGF antibody of the present disclosure may be an anti-VEGF antibody conjugate that includes a polymeric moiety that extends the half-life/effectiveness/properties of the antibody when administered to a subject. A method of the present disclosure includes administering one or more doses of an anti-VEGF antibody conjugate to a subject (e.g., human or other mammalian patient) in need of treating an eye disorder, where the anti-VEGF antibody conjugate may be administered less frequently than a standard anti-VEGF therapy to treat the eye disorder.

Abstract: A fluid-driven actuator 100 includes a bending actuator 200 including a first wall portion 201, a second wall portion 203 cooperating with the first wall portion 201 to define an undulating actuator profile. The bending actuator 200 also includes an inner fluid bladder 202 disposed between the first and second wall portions 201,203 and following the undulating actuator profile. The fluid-driven actuator 100 further includes a restraint member 300 arranged to cooperate with the bending actuator 200 to produce a plurality of motions in response to fluid supplied to the inner fluid bladder 202.

Abstract: The present invention relates to ligation and/or assembly of nucleic acid molecules. Particularly, a double-stranded target nucleic acid having overhangs of at least one nucleotide is ligated with another nucleic acid molecule capable of forming a stem-loop structure with an overhang of at least one nucleotide. The invention is suitable for tagging nucleic acid molecules. In specific embodiments, the overhangs can be produced by chemical cleavage of phosphorothioate-modified nucleic acid molecules. The invention further relates to the amplification of the ligated product, and using the resultant amplicon for assembly of multiple nucleic acid fragments.

Abstract: A system for configuring a UE-AMBR includes a MME to send the UE-AMBR to an eNB covering the serving cell of the UE, the eNB covering the serving cell of the UE establishes a radio access bearer of the UE on at least one secondary cell. The MME sends an AMBR of the UE in the primary eNB covering the serving cell of the UE and an AMBR of the UE in a secondary eNB to the primary eNB. The primary eNB sends the AMBR of the secondary eNB to the corresponding secondary eNB. The technical solutions of the present disclosure can make total rate of all non-GBR services of the UE be not larger than the UE-AMBR when the UE has multiple S1 bearers or one S1 bearer.

Abstract: A LED bulb apparatus has a bulb shell, a head cap, a driver circuit and at least one light strip. The bulb shell has a light passing shell and a bottom portion. A head cap has a neck portion, a first electrode and a second electrode. The neck portion of the head cap is connected to the bottom portion of the bulb shell forming a container space. A fluorescent layer covers the multiple LED modules. The driving current is transmitted via at least one of the top end and the bottom end of the light strip to the LED modules. The substrate has a light transmittance less than 50%.

Abstract: Provided herein are methods of treating eye disorders by administering an anti-VEGF antibody and/or conjugate to a subject having an eye disorder. The anti-VEGF antibody of the present disclosure may be an anti-VEGF antibody conjugate that includes a polymeric moiety that extends the half-life/effectiveness/properties of the antibody when administered to a subject. A method of the present disclosure includes administering one or more doses of an anti-VEGF antibody conjugate to a subject (e.g., human or other mammalian patient) in need of treating an eye disorder, where the anti-VEGF antibody conjugate may be administered less frequently than a standard anti-VEGF therapy to treat the eye disorder.

Abstract: The present disclosure provides an immobilized crude enzyme for degrading complex polycyclic aromatic hydrocarbons (PAHs) in soil and a preparation method thereof, and relates to the field of remediation of complex organics-polluted soil. The present disclosure particularly relates to an immobilized crude enzyme and a preparation method thereof. In the present disclosure, the immobilized crude enzyme for degrading complex PAHs in soil is prepared from an acid-modified chestnut inner shell and a crude enzyme solution of white rot fungi; and there are copper ions in the crude enzyme solution of the white rot fungi. The preparation method includes: 1, preparing a chestnut inner shell into a powdered material; 2, preparing modified biochar; 3, conducting immobilization.

Abstract: The invention relates to systems and techniques for manufacturing articles containing cellulosic material, a tackifier, and a binder, and related processes of making and using the cellulosic articles. In particularly exemplary embodiments, the manufactured articles are door skins, sometimes known as door facings, and doors made from the door skins. The article contains a lipophilic cellulosic material, a tackifier, and a binder.

Abstract: A hybrid organic-inorganic conductive thin film comprising an organic layer and a plurality of inorganic particles is disclosed, wherein the plurality of inorganic particles comprises a plurality of Cu particles that have an average particle size in a range between 20 nm and 45 nm. This hybrid organic-inorganic conductive thin film is allowed to be used as a hole injection layer (HIL) or a hole transport layer (HTL), so as to be applied in the manufacture of QLED element, OLED element, organic photovoltaic element, hybrid inorganic-organic photovoltaic element, O-FET, O-TFT, or photoreceptor. Moreover, experiment data have proved that, compared to the regular OLED element, the OLED element having the HIL made of the hybrid organic-inorganic conductive thin film has a significant enhancement in device efficiency.