Abstract: A microfluidic ion detection chip having a bubble brightening structure includes a substrate, an upper plate, two glass cover plates, and a foam board. The substrate is provided with a fluid mixing region, a lower optical detection through hole, and a lower gas flow channel. The upper plate is adhesively connected to the substrate and is provided with a sample outlet, an upper optical detection through hole, an upper gas flow channel, and two sample inlets, the upper gas flow channel and the lower gas flow channel are combined to form a gas flow channel. The two glass cover plates are respectively disposed at the lower optical detection through hole and the upper optical detection through hole. The foam board is provided with a foaming structure capable of generating bubbles and a surfactant coated on the foam board, the foam board is disposed at the gas flow channel.

Abstract: Provided are a preparation method for a CTL cell and an application thereof. The preparation method comprises the following steps of: inducing a CTL cell by using a tumor antigen PAP-GM-CSF sensitized DC cell; and knocking out a PD-1 gene of the CTL cell to obtain a PD-1 knock-out CTL cell. The CTL cell obtained by the preparation method can be used for preparing drugs for treatment of prostate cancer, especially for treating PAP-positive prostate cancer. The CTL cell does not cause CTL cell failure and anergy due to the tumor-expressed PD-L1 after being transfused into the body, thereby producing efficient specific cytotoxic effect on a tumor cell and improving the curative effect and reducing the side effect.

Abstract: Disclosed herein are approaches for forming dynamic DRAM devices without trench fill voids. A method may include providing a plurality of trenches in a substrate, the plurality of trenches defining a plurality of device structures, and depositing a plurality of layers over the device structures. The layers may include a first layer over the device structures, a second layer over the first layer, and a third layer over the second layer. The method may further include forming a plurality of contact trenches through the plurality of layers to expose one or more device structures of the plurality of device structures, and directing ions into a sidewall of the trenches at a non-zero angle, wherein the ions impact the third layer without impacting the second layer. The method may further include forming a fill material within the trenches after the ions are directed into the sidewall of the trenches.

Abstract: An autonomous floor cleaning robot includes a robot body defining a forward drive direction, a controller supported by the robot body, a drive supporting the robot body and configured to maneuver the robot across a surface in response to commands from the controller, a pad holder disposed on an underside of the robot body and configured to retain a removable cleaning pad during operation of the cleaning robot; and a pad sensor arranged to sense a feature of a cleaning pad held by the pad holder and generate a corresponding signal. The controller is responsive to the signal generated by the pad sensor, and configured to control the robot according to a cleaning mode selected from a set of multiple robot cleaning modes as a function of the signal generated by the pad sensor.

Abstract: A method for growing a single crystal silicon ingot by the Czochralski method having reduced deviation in diameter is disclosed.

Abstract: Provided is a probe card, comprising a guide plate and a shielding structure of single-layer or multi-layer. The guide plate comprises an upper surface, a lower surface, and at least one guide hole passing through the upper surface and the lower surface, and the guide hole is provided with an inner wall surface. At least one layer of the shielding structure is made of an electromagnetic absorption material or an electromagnetic reflection material, and the shielding structure is not connected to a ground. Each layer of the shielding structure is formed on the inner wall surface of the guide hole by means of atomic layer deposition or atomic layer etching, and a thickness of each layer is less than 1000 nm.

Abstract: Provided are a laser cutting device and a laser cutting method. The laser cutting device comprises a beam expanding element provided with a plurality of lens sets, wherein optical axes of the plurality of lens sets are located in the same line and each lens set comprises at least one lens; the beam expanding element is configured to convert an incident beam into a first beam; and a spectroscopic element arranged on a light path of an emitted light of the beam expanding element, and wherein the spectroscopic element is configured to convert the first beam into multiple second beams that are annular and spaced apart from each other.

Abstract: An optical system affixed to an electronic apparatus is provided, including a first optical module, a second optical module, and a third optical module. The first optical module is configured to adjust the moving direction of a first light from a first moving direction to a second moving direction, wherein the first moving direction is not parallel to the second moving direction. The second optical module is configured to receive the first light moving in the second moving direction. The first light reaches the third optical module via the first optical module and the second optical module in sequence. The third optical module includes a first photoelectric converter configured to transform the first light into a first image signal.

Abstract: The present disclosure discloses ?-carrageenase mutant OUC-CglA-DPQQ, which has an amino acid sequence as set forth in SEQ ID NO. 1 and an encoding gene as set forth in SEQ ID NO. 2. The ?-carrageenase mutant OUC-CglA-DPQQ is applied to degradation of carrageenan/preparation of ?-carrageenan oligosaccharides with high polymerization degree. The present disclosure further discloses a method for degrading carrageenan/preparing ?-carrageenan oligosaccharides with high polymerization degree by using the ?-carrageenase mutant OUC-CglA-DPQQ. The ?-carrageenase mutant OUC-CglA-DPQQ of the present disclosure can act on low viscosity carrageenan, and the polymerization degree of final product ?-carrageenan oligosaccharides is 10-20. The ?-carrageenase mutant of the present disclosure is excellent in enzymatic properties and specificity, and has important industrial application value and economic value in the preparation of ?-carrageenan oligosaccharides via an enzyme method.

Abstract: The present disclosure provides systems, methods, devices, and computer program products for cache eviction enforcement and multi-tenant distributed cache architectures and operations. Systems, methods, devices, and computer program products may access a slab of a multi-tenant caching system, perform an eviction review by sequentially reaping through the slab, based on the class size, flag a first cache item by the eviction review based on a header of the first cache item, wherein the header comprises a prefix indicative of an expiry time, confirm expiration of the first cache item via a lock and lookup operation, and evict the first cache item from the slab. Significant optimization and efficiency benefits may be realized through the slab organization, cache architectures, and operations discussed herein.

Abstract: A method of manufacturing a semiconductor device includes forming a multi-layer stack of alternating first layers of a first semiconductor material and second layers of a second semiconductor material on a semiconductor substrate, forming a first recess through the multi-layer stack, and laterally recessing sidewalls of the second layers of the multi-layer stack. The sidewalls are adjacent to the first recess. The method further includes forming inner spacers with respective seams adjacent to the recessed second layers of the multi-layer stack and performing an anneal treatment on the inner spacers to close the respective seams.

Abstract: A system can include a memory device with multiple management units, each management unit made up of multiple blocks, and a processing device, operatively coupled with the memory device, to perform various operations including identifying, among the management units, some complete management units and some incomplete management units, as well as performing one type of operation using one or more complete management units. The operations can also include performing another type of operation using one or more incomplete management units where this other type of operation include writing, to one or more incomplete management units, metadata associated with the data stored in complete management units.

Abstract: Provided is a probe card, comprising a guide plate and a shielding structure of single-layer or multi-layer. The guide plate comprises an upper surface, a lower surface, and at least one guide hole passing through the upper surface and the lower surface, and the guide hole is provided with an inner wall surface. At least one layer of the shielding structure is made of an electromagnetic absorption material or an electromagnetic reflection material, and the shielding structure is not connected to a ground. Each layer of the shielding structure is formed on the inner wall surface of the guide hole by means of atomic layer deposition or atomic layer etching, and a thickness of each layer is less than 1000 nm.

Abstract: Example apparatus disclosed include interface circuitry, machine readable instruction, and programmable circuitry to at least one of instantiate or execute the machine readable instructions to access source input data and target input data, identify a domain shift prediction based on at least one of a feature decorrelation of the source input data or a feature decorrelation of the target input data, the domain shift prediction a source domain prediction or a target domain prediction, initiate gradient propagation of a domain loss to determine data features for the domain shift prediction, and rank input data features for the domain shift prediction.

Abstract: A mobile cleaning robot can include a robot body, a bumper, and a bumper impact system. The bumper can be connected to and supported by the robot body. The bumper impact system can include a first sensor connected to the body in a first orientation with respect to the body and the bumper. The bumper impact system can include a second sensor connected to the body in a second orientation with respect to the body and the bumper different from the first orientation. The first sensor and the second sensor can together be configured to sense an impact region of the bumper based on a magnitude and a direction of movement of the bumper relative to the robot body.

Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.

Abstract: A human condition detection device comprises a depth image-taking module for taking a depth image of a target area. A millimeter-wave radar module detects breaths or heartbeats in the target area to provide a signal. A thermal image-taking module takes a thermal image of the target area. A processor module determines whether a person is in the target area based on the depth image. The processor module determines whether there is any breath or heartbeat based on the signal if a person is in the target area. The processor module determines whether there is any abnormal vital sign of the person in the target area based on the signal and the thermal image if there is a breath or heartbeat in the target area. The processor module actuates the warning module to provide a warning if there is an abnormal vital sign of the person in the target area.

Abstract: A solid-state light-emitting device includes: a substrate; an epitaxial layer structure on the substrate and including a first-type area and a second-type area; a first current blocking layer disposed on the epitaxial layer structure and located in the first-type area; a current spreading layer covering the first current blocking layer so that the first current blocking layer is located between the current spreading layer and the epitaxial layer structure; a first adhesive reinforcing layer disposed on a side of the current spreading layer away from the first current blocking layer and including a plurality of first through holes; a first electrode disposed on a side of the first adhesion reinforcing layer away from the current spreading layer and filled into the plurality of first through holes to electrically contact with the current spreading layer. Therefore, the light-emitting efficiency of the solid-state light-emitting device is improved.

Abstract: In a method of manufacturing a semiconductor device, a lower conductive layer is formed in an opening formed in a dielectric layer, and the lower conductive layer is recessed to form a space. A blanket conductive layer is formed over the recessed lower conductive layer in the space, a sidewall of the space and an upper surface of the dielectric layer. Part of the blanket conductive layer formed on the sidewall of the opening and the upper surface of the dielectric layer is removed, thereby forming a upper conductive layer on the lower conductive layer, and a cap insulating layer is formed over the upper conductive layer in the space. The blanket conductive layer is formed by physical vapor deposition.

Abstract: System and techniques for tracking caloric expenditure using sensor driven fingerprints are described herein. A set of outputs may be obtained from a plurality of sensors. A fingerprint may be generated using the set of outputs. The fingerprint may correspond to an activity observed by the plurality of sensors. The generated fingerprint may be compared to a set of fingerprints stored in a database. Each fingerprint of the set of fingerprints may correspond to a respective caloric expenditure. A caloric expenditure may be calculated for the activity based on the comparison. An exercise profile of a user may be updated using the caloric expenditure.