Patents by Inventor Hong Xu

Hong Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11997768
    Abstract: An LED filament comprising a plurality of LED filament units, each of the plurality of LED filament units includes a LED chip with an upper surface and a lower surface opposite to the upper surface of the LED chip, and a light conversion layer comprising a top layer and a base layer, and the base layer comprises an upper surface and a lower surface opposite to the upper surface of the base layer, where the top layer with an upper surface and a lower surface opposite to the upper surface of the top layer is disposed on at least two sides of each of the LED chips, the lower surface of each of the LED chips is close to the upper surface of the base layer, and the upper surface of the top layer is away from each of the LED chips.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: May 28, 2024
    Assignee: ZHEJIANG SUPER LIGHTING ELECTRIC APPLIANCE CO., LTD
    Inventors: Tao Jiang, Wei-Hong Xu, Yukihiro Saito, Hayato Unagiike, Ai-Ming Xiong, Jun-Feng Xu, Yi-Ching Chen
  • Patent number: 11987642
    Abstract: Provided herein are compositions, methods, and uses involving bispecific binding molecules that specifically bind to HER2, a receptor tyrosine kinase, and to CD3, a T cell receptor, and mediate T cell cytotoxicity for managing and treating disorders, such as cancer. Also provided herein are uses and methods for managing and treating HER2-related cancers.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: May 21, 2024
    Assignee: Memorial Sloan Kettering Cancer Center
    Inventors: Nai-Kong V. Cheung, Andres Lopez-Albaitero, Hong Xu
  • Publication number: 20240106217
    Abstract: The present invention discloses a manual type C-shaped wire clamp operating device, includes an insulating operating rod, wherein an upper end of the insulating operating rod is provided with a threaded rod, and the threaded rod includes an upper thread and a lower thread; a wire clamp clamping device, wherein the wire clamp clamping device includes a first spring, a wire clamp seat and a floating clamping block located above the wire clamp seat, a wire clamp seat threaded hole is formed in the wire clamp seat, the wire clamp seat threaded hole is in fit connection with the lower thread of the threaded rod; a drainage wire pressing device, wherein the drainage wire pressing device includes a guide rod arranged on the wire clamp seat and a drainage wire pressing block sliding along the guide rod, and a pressing block threaded hole is formed in the drainage wire pressing block.
    Type: Application
    Filed: December 9, 2022
    Publication date: March 28, 2024
    Applicant: STATE GRID ZHEJIANG TONGXIANG ELECTRIC POWER SUPPLY COMPANY
    Inventors: Dong Qian, Guoliang Liu, Hong Xu, Chongxi Zhu, Shengwei Shen, Jinfan Sun, Aoyang Hu, Wei Zeng
  • Publication number: 20240092884
    Abstract: An anti-ANGPTL3 antibody or an antigen-binding fragment thereof. The present invention provides an anti-ANGPTL3 antibody or an antigen-binding fragment thereof, wherein a heavy chain variable region includes complementarity determining regions (CDRs), including CDR-H1 having an amino acid sequence as set forth in SEQ ID No. 1, CDR-H2 having an amino acid sequence as set forth in SEQ ID No. 2, and CDR-H3 having an amino acid sequence as set forth in SEQ ID No. 3; and the CDRs of a light chain variable region includes CDR-L1 having an amino acid sequence as set forth in SEQ ID No. 4, CDR-L2 having an amino acid sequence as set forth in SEQ ID No. 5, and CDR-L3 having an amino acid sequence as set forth in SEQ ID No. 6. The antibody or the antigen-binding fragment thereof provided in the present invention can specifically recognize ANGPTL3.
    Type: Application
    Filed: March 30, 2021
    Publication date: March 21, 2024
    Applicant: CHILDREN'S HOSPITAL OF FUDAN UNIVERSITY
    Inventors: HONG XU, QIAN SHEN, JIA RAO, YIHUI ZHAI, LI SUN, HAIMEI LIU, QIANYING LV, XINLI HAN
  • Publication number: 20240093171
    Abstract: A chimeric lysozyme variant has an improved heat resistance and is encoded by a polynucleotide. A novel chimeric lysozyme sequence is constructed, and high-efficiency expression in a host cell is achieved. The thermal stability of the chimeric lysozyme under the condition of 60° C. is nearly doubled compared to a parental sequence. The chimeric lysozyme variant can be used to prepare product that is antibiotic, for example, animal feed additive containing the chimeric lysozyme variant and an animal feed containing the animal feed additive.
    Type: Application
    Filed: November 12, 2021
    Publication date: March 21, 2024
    Inventors: Fei ZHENG, Ting YAN, Jidong ZHU, Hong XU, Yan SUN, Yanjie LIU
  • Patent number: 11930426
    Abstract: Examples of detecting whether a device meets an enrollment level are disclosed. In one case, a method for providing access to an application on a client device includes receiving a request to access an application from the client device, determining an enrollment level associated with the application, and determining that multi-factor authentication is required for access to the application on the client device based on the enrollment level associated with the application. The method can also include initiating multi-factor authentication on the client device before access to the application is permitted. The method can also include determining that multi-factor authentication is successful on the client device, transmitting a management component to the client device, and installing the management component on the client device for enrollment as a managed device with a management service.
    Type: Grant
    Filed: December 24, 2020
    Date of Patent: March 12, 2024
    Assignee: AirWatch LLC
    Inventors: Adam Stephen Rykowski, Ashish Jain, Dale Robert Olds, Emily Hong Xu, Kabir Barday, Kyle Austin, Sridhara Babu Kommireddy, Pratik Jagad, Krishna Kumar Bhavesh
  • Publication number: 20240077801
    Abstract: Disclosed are a zinc-based metal organic nanoparticle and a preparation method therefor, and a photoresist. The zinc-based metal organic nanoparticle has a core-shell structure, and the general formula is ZnxOy[A]2x[B]2, wherein x is 2 or 3, and 2x?y?4x, ZnxOy is a kernel of the core-shell structure, A is a first organic ligand, B is a second organic ligand, the first organic ligand A and the second organic ligand B together form an outer shell of the core-shell structure, the first organic ligand A is selected from one or more of a substituted or unsubstituted aliphatic group and a substituted or unsubstituted aromatic group, and the second organic ligand B is selected from one or more of an organic amine and a derivative thereof.
    Type: Application
    Filed: December 23, 2021
    Publication date: March 7, 2024
    Inventors: Hong XU, Xiangming HE, Hao CUI
  • Publication number: 20240077977
    Abstract: Disclosed is a method and system for predicting a touch interaction position on a large display based on a binocular camera. The method includes: separately acquiring arm movement video frames of a user and facial and eye movement video frames of the user by a binocular camera; extracting a video clip of each tapping action from the arm movement video frames and the facial and eye movement video frames and obtaining a key frame by screening; marking the key frame of each tapping action with coordinates to indicate coordinates of a finger in a display screen; inputting the marked key frame to an efficient convolutional network for online video understanding (ECO)-Lite neural network for training to obtain a predictive network model; and inputting a video frame of a current operation to be predicted to the predictive network model and outputting a touch interaction position predicted for the current operation.
    Type: Application
    Filed: September 5, 2023
    Publication date: March 7, 2024
    Inventors: Gangyong JIA, Yumiao ZHAO, Huanle RAO, Ziwei SONG, Minghui YU, Hong XU
  • Patent number: 11905615
    Abstract: In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: February 20, 2024
    Assignee: Stamford Devices Limited
    Inventor: Hong Xu
  • Publication number: 20240052561
    Abstract: A digital control method is to accurately calculate the real-time addition amount of each dye in the solution replenishment system in the whole dyeing process based on the initial dyeing rate of each dye, and replenish the dye solution according to the real-time addition amount. A digital control system includes an automatic calculation K0,n value unit, a central processing unit and a replenishment pump. The automatic calculation K0,n value unit is composed of a dye solution concentration detection instrument, a sensor I and a BP neural network model. The BP neural network model is a BP neural network trained by a dye database. The automatic calculation K0,n value unit transmits the K0,n value to the central processing unit, calculates the replenishment amount through the central processing unit, and controls the replenishment pump to replenish the solution.
    Type: Application
    Filed: December 28, 2021
    Publication date: February 15, 2024
    Applicant: DONGHUA UNIVERSITY
    Inventors: Zhiping MAO, Yamin DAI, Hong XU, Yi ZHONG, Hui LU, Linping ZHANG, Xiaofeng SUI, Wei WU
  • Publication number: 20240043281
    Abstract: A photoresist, a photoresist composition, a method for patterning a photoresist and a method for preparing a printed circuit board are disclosed in the present application. The photoresist includes an organic solvent and titanium zirconium oxide nanoparticles. The general molecular formula of the titanium zirconium oxide nanoparticles is TixZryOzLn, wherein x, y and z are each independently an integer in a range from 1 to 6, n is an integer in a range from 5 to 30, and L is an organic ligand including a free-radical polymerizable group.
    Type: Application
    Filed: December 7, 2021
    Publication date: February 8, 2024
    Inventors: HONG XU, XIANG-MING HE, XIAO-LIN WANG
  • Publication number: 20240037111
    Abstract: Some embodiments provide a non-transitory machine-readable medium that stores a program. The program receives, from a client device, a request for information associated with a category. In response to the request, the program further accesses a storage to retrieve a first value associated with the category. The program also determines a set of values associated with the category based on a plurality of transactions. The program further determines an optimization level value associated with the category. The program also determines a second value associated with the category based on the first value, the set of values, and the optimization level value. The program further provides, by an application operating on the device, a graphical user interface (GUI) to the client device, the GUI comprising the second value.
    Type: Application
    Filed: October 12, 2023
    Publication date: February 1, 2024
    Inventors: Hong Xu, Roberto Valdovinos, Jason Kirst
  • Publication number: 20240026037
    Abstract: The present disclosure relates generally to immunoglobulin-related compositions (e.g., multi-specific antibodies or antigen binding fragments thereof) that can bind to the GPA33 protein. The multi-specific antibodies of the present technology are useful in methods for detecting and treating a GPA33-associated cancer in a subject in need thereof.
    Type: Application
    Filed: November 17, 2021
    Publication date: January 25, 2024
    Inventors: Brian H. SANTICH, Mao WANG, Nai-Kong V. CHEUNG, Steven LARSON, Sarah CHEAL, Darren VEACH, Mahiuddin AHMED, Hong XU
  • Patent number: 11872573
    Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 ?m thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: January 16, 2024
    Assignee: Stamford Devices Limited
    Inventors: Brendan Hogan, Hong Xu
  • Publication number: 20240014602
    Abstract: An electrical connector locking and stabilizing structure includes a socket connector including a seat body with a docking space, conductive terminals pierced on two sides of the docking space and a metal shell assembled on the seat body with a button hole formed in each of two limit frames thereof, and a plug connector including a base having a bottom insertion portion combined with the docking space and mounted with contact terminals that are electrically connected to a transmission unit located on the top surface of the base, a shielding shell assembled with the base and having two pushing portions respectively provided with a shaft groove and a supporting portion, and a handle having two shaft portions respectively extending into the shaft grooves and the button holes with the top side limited by the limit frames and two side rods with the bottom side stopped against the supporting portions.
    Type: Application
    Filed: May 3, 2023
    Publication date: January 11, 2024
    Inventors: Yuan-Huang LIU, Jia-Hong XU
  • Publication number: 20240002501
    Abstract: The present disclosure relates generally to immunoglobulin-related compositions (e.g., antibodies or antigen binding fragments thereof) that can bind to and neutralize the activity of L1-CAM protein. The antibodies of the present technology are useful in methods for detecting and treating a L1-CAM-positive cancer in a subject in need thereof.
    Type: Application
    Filed: March 6, 2023
    Publication date: January 4, 2024
    Inventors: Nai-Kong V. CHEUNG, Hong XU, Maya SUZUKI-NISHIJIMA, Brandon NEMIEBOKA, Jason LEWIS
  • Patent number: 11858993
    Abstract: Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: January 2, 2024
    Assignees: Memorial Sloan Kettering Cancer Center, Massachusetts Institute of Technology
    Inventors: Sarah Cheal, Hong Xu, Steven Larson, Nai-Kong Cheung, Karl Dane Wittrup, Alice Tzeng
  • Patent number: 11833615
    Abstract: The disclosure provides a method for preparing a multiple-material variable-rigidity component by efficient collaborative additive manufacturing, relates to the technical field of additive manufacturing. In the disclosure, the method comprises: pretreating a component structure model and dividing the component structure model into a lightweight part with complex pore structures and a solid part that needs to be manufactured rapidly; preparing the lightweight part by a selective laser melting prototyping; performing a surface treatment on the prepared lightweight part to obtain a treated lightweight part; preparing the solid part on the treated lightweight part by a wire arc additive manufacturing, to obtain a component.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: December 5, 2023
    Assignee: North University of China
    Inventors: Yu Wang, Fumin Hou, Hong Xu, Hongkui Mao, Guowei Zhang, Zhonghua Li, Bin Liu, Peikang Bai, Zhanyong Zhao, Xin Cao, Bingxin Guo, Zongyi Fan
  • Patent number: 11834707
    Abstract: A nucleic acid amplification blocker for detecting a low-abundance mutation sequence and an application thereof in detecting a low-abundance mutation sequence are provided. The nucleic acid amplification blocker is an oligonucleotide modified by locked nucleic acid (LNA), and the matching region of the nucleic acid amplification blocker is located between amplified sequences. The nucleic acid amplification blocker is completely complementary to wild-type gene sequence, and contains at least one mismatch with mutant sequence. The nucleic acid amplification blocker has a great difference in affinity with mutant nucleic acid sequence/wild-type nucleic acid sequence, so as to achieve the purpose of highly selective amplification/enrichment of mutant sequence in samples. The nucleic acid amplification blocker has more significant detection effect on deletion mutation and insertion mutation.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: December 5, 2023
    Assignee: SHANGHAI MAG-GENE NANOTECH CO., LTD.
    Inventors: Hong Xu, Hao Yang, Gaolian Xu, Hongchen Gu
  • Patent number: 11834781
    Abstract: The disclosure provides a method of continuous dyeing with reactive dyes in wet conditions, the method including: 1) adding fabric to a mixture of a dye liquor and an alkali through a one-bath-one-step method; 2) immersing the fabric pretreated in 1) in a padding liquor with an air film horizontal pad dyeing machine; 3) preheating the fabric after being treated in 2) at a temperature of 50-90° C.; and 4) rolling and batching the fabric after being treated in 3) at a temperature of 10-70° C. for 2-72 hours.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: December 5, 2023
    Assignees: HUAFANG CO., LTD, DONGHUA UNIVERSITY, BINZHOU HUA TEXTILE ENGINEERING TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
    Inventors: Zhiping Mao, Hongyu Sun, Chunguang Li, Rongxia Jia, Yi Zhong, Hong Xu, Limin Wang, Qi Yu, Xiaomin Liu, Qingbo Lu, Chunying Sheng, Engang Lu, Qisheng Zhao, Wei Wu, Yamin Dai, Jinbo Wang