Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: The exemplary embodiments relate to a user equipment (UE) performing radio link monitoring of a sidelink. The UE may transmit a signal over the sidelink and receive an indication of a type of hybrid automatic repeating request (HARQ) feedback in response to the signal. The UE may then generate a radio link metric associated with the sidelink based on the type of HARQ feedback. The UE may determine that the radio link metric satisfies a predetermined threshold and initiate a keep alive procedure for the sidelink based on the radio link metric satisfying the predetermined threshold.

Abstract: Methods, systems, and devices for wireless communications are described. In some systems, a user equipment (UE) may support cellular communications (e.g., Uu signaling) in a first frequency range and may support sidelink communications in a second, higher frequency range. To reduce the processing overhead and latency involved in sidelink discovery in the second frequency range, the UE may use Uu signaling in the first frequency range to assist with the sidelink discovery. For example, the UE may determine, based on a configuration, an uplink message supporting UE detection in the first frequency range to support sidelink discovery. The UE may monitor for the uplink message in the first frequency range and may detect a second UE based on the monitoring. The UEs may establish a sidelink connection for sidelink communications in the second frequency range based on the detection of the second UE in the first frequency range.

Abstract: To extend a physical broadcast channel (PBCH) in wireless communications, an extended physical broadcast channel (EPBCH) transmission is generated with one or more legacy PBCH blocks and one or more EPBCH blocks within an extension window. A size of the extension window is determined based at least in part on a PBCH repetition number and a number of the legacy PBCH blocks relative to a number of the EPBCH blocks. The EPBCH transmission is transmitted by a base station (BS) to one or more user equipment (UE).

Abstract: The present disclosure relates to a communication method and system for converging a 5th-Generation (5G) communication system for supporting higher data rates beyond a 4th-Generation (4G) system with a technology for Internet of Things (IoT). The present disclosure may be applied to intelligent services based on the 5G communication technology and the IoT-related technology, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services. According to an aspect of the embodiments of the present disclosure, a method for supporting handover is provided, comprising: receiving a message from a central unit control plane entity of a target base station; receiving a data packet from a source base station; and discarding a packet data convergence protocol (PDCP) service data unit (SDU) including the PDCP sequence number (SN) in the received data packet according to the indication of the message.

Abstract: The present disclosure provides an information configuration method, an information interaction method, and an address information update method. The information configuration method may be performed by a first node, and may include: transmitting, to a second node, a first configuration request message comprising a request for a bearer context setup; receiving, from the second node, a first configuration response message comprising a response to the bearer context setup request in the first configuration request message; and establishing a bear context based on the first configuration response message, wherein the first configuration request message comprises at least one of information related to data profile, or profile indication information.

Abstract: A display substrate and a display device are provided. The display substrate includes a base substrate, at least one group of contact pads, a plurality of first light-emitting elements, a plurality of first pixel driving circuits, a plurality of connecting traces, a plurality of data lines and a plurality of leads. The display area includes a first display area and a second display area; the first light-emitting elements are located in the first display area; the first pixel driving circuits are located in the second display area; the leads are located in the first display area and the peripheral area, and connect the data lines and the at least one group of contact pads; orthographic projections of the first light-emitting elements on a substrate surface of the base substrate are at least partly overlapped with orthographic projections of the leads on the substrate surface of the base substrate.

Abstract: The present invention discloses a manual type C-shaped wire clamp operating device, includes an insulating operating rod, wherein an upper end of the insulating operating rod is provided with a threaded rod, and the threaded rod includes an upper thread and a lower thread; a wire clamp clamping device, wherein the wire clamp clamping device includes a first spring, a wire clamp seat and a floating clamping block located above the wire clamp seat, a wire clamp seat threaded hole is formed in the wire clamp seat, the wire clamp seat threaded hole is in fit connection with the lower thread of the threaded rod; a drainage wire pressing device, wherein the drainage wire pressing device includes a guide rod arranged on the wire clamp seat and a drainage wire pressing block sliding along the guide rod, and a pressing block threaded hole is formed in the drainage wire pressing block.

Abstract: The present disclosure provides an information configuration method, an information interaction method, and an address information update method. The information configuration method may be performed by a first node, and may include: transmitting, to a second node, a first configuration request message comprising a request for a bearer context setup; receiving, from the second node, a first configuration response message comprising a response to the bearer context setup request in the first configuration request message; and establishing a bear context based on the first configuration response message, wherein the first configuration request message comprises at least one of information related to data profile, or profile indication information.

Abstract: A method and an apparatus of establishing dual-connectivity to transmit data are disclosed. A PCell of the UE carries out a mapping function and realizes a PDCP layer, a RLC layer, a MAC layer and a physical layer, and a SCell of the UE carries out quality packet data to data radio bearer mapping and realizes a PDCP layer, a MAC layer and a physical layer, in which a core network transmits data of the UE to the PCell, the PCell maps a QoS Flow of the data of the UE which is quality packet data to a data radio bearer on a mapping layer, performs path split, transmits data of respective paths to the UE through the PCell and SCell of the UE, and the UE regroups the data of the respective paths on the PDCP layer, and transmits the regrouped data to an application layer.

Abstract: Apparatuses, systems, and methods for multi-TRP by a UE, including out of order delivery of PDSCH, PUSCH, and/or DL ACK/NACK. The UE may receive, from a base station, a configuration that may include multiple control resource set (CORESET) pools and each CORESET pool may be associated with an index value. The UE may determine that at least two DCIs of the multiple DCIs end at a common symbol and determine, based on one or more predetermined rules, when the UE may be scheduled to receive PDSCHs, transmit PUSCHs, and/or transmit ACK/NACKs from CORESETs associated with the at least two DCIs.

Abstract: Apparatuses, systems, and methods for multi-TRP by a UE, including out of order delivery of PDSCH, PUSCH, and/or DL ACK/NACK. The UE may receive, from a base station, a configuration that may include multiple control resource set (CORESET) pools and each CORESET pool may be associated with an index value. The UE may determine that at least two DCIs of the multiple DCIs end at a common symbol and determine, based on one or more predetermined rules, when the UE may be scheduled to receive PDSCHs, transmit PUSCHs, and/or transmit ACK/NACKs from CORESETs associated with the at least two DCIs.

Abstract: An anti-ANGPTL3 antibody or an antigen-binding fragment thereof. The present invention provides an anti-ANGPTL3 antibody or an antigen-binding fragment thereof, wherein a heavy chain variable region includes complementarity determining regions (CDRs), including CDR-H1 having an amino acid sequence as set forth in SEQ ID No. 1, CDR-H2 having an amino acid sequence as set forth in SEQ ID No. 2, and CDR-H3 having an amino acid sequence as set forth in SEQ ID No. 3; and the CDRs of a light chain variable region includes CDR-L1 having an amino acid sequence as set forth in SEQ ID No. 4, CDR-L2 having an amino acid sequence as set forth in SEQ ID No. 5, and CDR-L3 having an amino acid sequence as set forth in SEQ ID No. 6. The antibody or the antigen-binding fragment thereof provided in the present invention can specifically recognize ANGPTL3.

Abstract: A chimeric lysozyme variant has an improved heat resistance and is encoded by a polynucleotide. A novel chimeric lysozyme sequence is constructed, and high-efficiency expression in a host cell is achieved. The thermal stability of the chimeric lysozyme under the condition of 60° C. is nearly doubled compared to a parental sequence. The chimeric lysozyme variant can be used to prepare product that is antibiotic, for example, animal feed additive containing the chimeric lysozyme variant and an animal feed containing the animal feed additive.

Abstract: The present disclosure discloses a rolling ring shrink fitting tool for rotary equipment, including a lifting frame; a movement slot is formed in a bottom surface of a top of the lifting frame; an output end of a first motor is connected with a main gear; guide rollers are embedded in a lifting seat through bearings; shrink fitting plates are two semicircular structures; lifting lugs are welded on outer sides of the shrink fitting plates; tooth rings are arranged outside the shrink fitting plates; stop rods are fixed on inner walls of the tooth rings; supporting screw rods are embedded at sunken positions on inner walls of the shrink fitting plates through bearings.

Abstract: The present disclosure relates to a communication method and system for converging a 5th-Generation (5G) communication system for supporting higher data rates beyond a 4th-Generation (4G) system with a technology for Internet of Things (IoT). The present disclosure may be applied to intelligent services based on the 5G communication technology and the IoT-related technology, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services. The present application relates to the field of wireless communication technologies, and discloses a method for processing an Radio Link Control (RLC) failure, an electronic device and a computer readable storage medium. The method includes: receiving, by a first network device, RLC failure related information of a user equipment (UE); processing the RLC failure correspondingly by interacting with a second network device, based on the received RLC failure related information.

Abstract: In wireless communication, an improved change of a schedule request (“SR”) resource configuration is provided. The SR resource configuration may be transmitted from a basestation to user equipment (“UE”) and may include a parameter for the configuring of one or more SRs. A validity of the SR resource configuration is determined based on predefined information or high layer signaling.

Abstract: In wireless communication, a configuration of uplink (“UL”) signaling transmissions can be through a specific window or pattern. The UL transmission can be concentrated in a time period to save power. Specifically, an active time is determined as a time period for UL signals. Non-active time may include different types of UL signals. The active time may be configured and enabled under different conditions.

Abstract: The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). The embodiments of the present invention provide methods and devices for network access. The method includes receiving a first request message forwarded by a distributed unit in a base station and indication information of the distributed unit with respect to the first request message, the first request message requesting to connect a user equipment to a network; determining a processing to be performed on the first request message based on the indication Information; and transmitting an indication of the determined processing to the distributed unit.

Abstract: A bottom touching assisting device suitable for deep-sea submersibles and an implementation method thereof are provided. Four support columns are arranged within a mounting box body at a bottom of a deep-sea submersible, the support columns and the mounting box body are connected in a sliding manner through sliders, and the support column is sleeved with a threaded sleeve in a threaded connection manner. In conjunction with a drive component and a pressing mechanism, smooth vertical movement of the support column is achieved when the threaded sleeve rotates. This allows a bottom end of the support column to extend from the mounting box body.