Patents by Inventor Hong Xue

Hong Xue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uses of dl-THP
    Patent number: 6521634
    Abstract: The present invention is concerned with new, previously unsuggested, therapeutic uses of dl-THP (dl-tetrahydropalmatine) including anxiety disorders, seizures, and status epilepticus.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: February 18, 2003
    Assignee: The Hong Kong University of Science & Technology
    Inventors: Hong Xue, Sek Lun Law
  • Method for detecting single nucleotide polymorphisms (SNP'S) and point mutations
    Publication number: 20030017487
    Abstract: A method of genotyping single nucleotide polymorphisms (“SNP”) and point mutations in nucleic acid based on chain extension by polymerase. This invention is based on the fact that the nucleoside immediately 5′ adjacent to any SNP/point mutation site is known, and the neighboring sequence immediately 3′ adjacent to the site is also known. A primer complementary to the sequence directly adjacent to the SNP on the 3′ side in a target polynucleotide is used for chain elongation. The polymerase reaction mixture contains one chain-terminating nucleotide having a base complementary to the nucleotide directly adjacent to the SNP on the 5′ side in the target polynucleotide. An additional dNTP may be added to produce a primer with the maximum of a two-base extension. The resultant elongation/termination reaction products are analyzed for the length of chain extension of the primer, or for the amount of label incorporation from a labeled form of the terminator nucleotide.
    Type: Application
    Filed: June 4, 2002
    Publication date: January 23, 2003
    Applicant: PharmacoGenetics, Ltd.
    Inventors: Hong Xue, Jeffrey Tze-Fei Wong
  • Method for detecting single nucleotide polymorphisms (SNPs) and point mutations
    Publication number: 20020187477
    Abstract: A method of genotyping single nucleotide polymorphisms (SNP) and point mutations in nucleic acid based on chain extension by polymerase. This invention is based on the fact that the nucleoside immediately 5′ adjacent to any SNP/point mutation site is known, and the neighboring sequence immediately 3′ adjacent to the site is also known. A primer complimentary to the sequence directly adjacent the 3′ side of the SNP in a target polynucleotide is used for chain elongation. The polymerase reaction mixture contains one chain terminating nucleotide having the base complimentary to nucleotide directly adjacent to the 5′ side of the SNP of the target polynucleotide. An additional dNTP may be added to produce a primer with the maximum of two base extension. The resultant elongation/termination reaction product are analysed for incorporation of the chain terminator nucleotide or for chain length extension of the primer.
    Type: Application
    Filed: June 6, 2001
    Publication date: December 12, 2002
    Inventors: Hong Xue, Jeffrey Tze Fel Wong
  • Novel uses of dl-THP
    Publication number: 20020143067
    Abstract: The present invention is concerned with new, previously unsuggested, therapeutic uses of dl-THP (dl-tetrahydropalmatine).
    Type: Application
    Filed: March 28, 2001
    Publication date: October 3, 2002
    Inventors: Hong Xue, Sek Lun Law