Abstract: The invention provides methods for treating a patient with chronic constipation by administering a therapeutically effective dose of linaclotide.

Abstract: A method for forming an ink jet printhead comprises processing an epoxy adhesive such that negative effects from physical contact with particular inks are reduced or eliminated. Conventional adhesives processed using conventional techniques are known to gain weight and squeeze out when exposed to certain inks such as ultraviolet inks and pigmented inks. An embodiment of the present teachings can include processing of a particular adhesive such that the resulting epoxy adhesive is suitable for printhead applications.

Abstract: A method for forming an ink jet printhead comprises processing an epoxy adhesive such that negative effects from physical contact with particular inks are reduced or eliminated. Conventional adhesives processed using conventional techniques are known to gain weight and squeeze out when exposed to certain inks such as ultraviolet inks, solid inks, and aqueous inks. An embodiment of the present teachings can include processing of a particular adhesive such that the resulting epoxy adhesive is suitable for printhead applications.

Abstract: A thermal bubble jetting device including a substrate. A superoleophobic, textured surface is positioned on the substrate. The textured surface comprises one or more gaps configured for holding a gas. A receptacle is positioned in fluid communication with the textured surface. Both an inlet and nozzle are in fluid communication with the receptacle. The device includes a heater mechanism configured to expand a gas in the one or more gaps so as to sufficiently increase pressure in the receptacle to force liquid through the nozzle.

Abstract: A system and method of model predictive control executes a model predictive control (MPC) controller of a subject dynamic process (e.g., processing plant) in a configuration mode, identification mode and model adaptation mode. Users input and specify model structure information in the configuration mode, including constraints. Using the specified model structure information in the identification mode, the MCP controller generates linear dynamic models of the subject process. The generated linear dynamic models collectively form a working master model. In model adaptation mode, the MPC controller uses the specified model structure information in a manner that forces control actions based on the formed working master model to closely match real-world behavior of the subject dynamic process. The MPC controller coordinates execution in identification mode and in model adaptation mode to provide adaptive modeling and preserve structural information of the model during a model update.

Abstract: A device and method for preparing a device having a superoleophobic surface are disclosed. The method includes providing a substrate; coating a lift-off resist layer on the substrate; baking the lift-off resist layer; layering a photoresist layer on the lift-off resist layer; performing photolithography to create a textured pattern in the photoresist layer and the lift-off resist layer, and chemically modifying the textured pattern to create a superoleophobic surface.

Abstract: Polymer conjugates containing a C1-inhibitor having at least one substantially non-antigenic polymer covalently attached to the C1-inhibitor via glycan group of the C1 inhibitor is provided. In addition, methods of making the conjugates as well as methods of treatment using the conjugate of the present invention are also provided.

Abstract: A method and apparatus for activating a function of the electronic device is disclosed herewith. The method includes detecting a first input by a motion sensor. Further, the method activates a touch sensor of the electronic device in response to detecting the first input. The method then detects a second input by the motion sensor within a predetermined time period from the first input. Next, the method determines, in response to detecting the second input, whether contact has occurred at the touch sensor and activates a function of the electronic device in response to determining that contact has occurred at the touch sensor when the second input is detected.

Abstract: Polymer conjugates containing a C1-inhibitor having at least one substantially non-antigenic polymer covalently attached to the C1-inhibitor via thiol group of the C1 inhibitor is provided. In the polymer conjugates of the present invention, the substantially non-antigenic polymer is attached to either free thiol from a cysteine of thiol generated from disulfide bonds in C1 inhibitor. Alternatively, the substantially non-antigenic polymer is attached to one of more thiols in C1 inhibitor via bifunctional spacer. In addition, methods of making the conjugates as well as methods of treatment using the conjugate of the present invention are also provided.

Abstract: Various embodiments provide oleophobic, low adhesion coatings with high thermal stability and methods of forming and using them in an ink jet printhead, wherein the oleophobic, low adhesion coatings can include a sol-gel cross-linked coating by a self-condensation process of at least a silane-functionalized perfluoropolyether based polymer precursor.

Abstract: A method for forming an ink jet printhead comprises processing an epoxy adhesive such that negative effects from physical contact with particular inks are reduced or eliminated. Conventional adhesives processed using conventional techniques are known to gain weight, swell, and/or oxidize when exposed to certain inks such as ultraviolet inks and pigmented inks. An embodiment of the present teachings can include processing of an adhesive including a processes a particular adhesive comprising a cresol novolac resin and a dicydiandiamide curing agent using a particular process, such that the resulting epoxy adhesive is suitable for printhead applications.

Abstract: A system and method for selecting a wireless network is disclosed. The method relates to selecting a wireless network from a plurality of wireless networks. A variation of the invention includes selecting a new platform from a plurality of platforms offered by the current service provider according to a service request from the wireless device. The method comprises determining a requested service associated with the wireless device, determining whether one of the plurality of wireless networks can provide the requested service, and, if one of the plurality of wireless networks can provide the requested service, choosing the one wireless network of the plurality of wireless networks. The method further involves using a variety of parameters in determining which wireless network to choose for servicing the requested service from the wireless device. These parameters include quality of services, application supported, or other business factors such as roaming agreements, traffic load and cost of services.

Abstract: Solid, stable formulations of linaclotide suitable for oral administration are described herein as are methods for preparing such formulations. The formulations described herein contain a polypeptide consisting of the amino acid sequence Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr (“linaclotide”; SEQ ID NO:1) or a pharmaceutically acceptable salt thereof. The linaclotide formulations described herein are stable and have a sufficient shelf life for manufacturing, storing and distributing the drug.

Abstract: Solid, stable formulations of linaclotide suitable for oral administration are described herein as are methods for preparing such formulations. The formulations described herein contain a polypeptide consisting of the amino acid sequence Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr (“linaclotide”; SEQ ID NO:1) or a pharmaceutically acceptable salt thereof. The linaclotide formulations described herein are stable and have a sufficient shelf life for manufacturing, storing and distributing the drug.

Abstract: An electronic device (200) includes a single antenna (211), a communication circuit (202), and a RFID circuit (207). A switch (212) selectively couples the single antenna to one of the communication circuit or the RFID circuit. For example, the RFID circuit can be coupled to the single antenna when the electronic device is OFF, and the communication circuit can be coupled to the single antenna when the electronic device is ON. Accordingly, RFID information can be received from an RFID communication device when the electronic device is OFF. When the electronic device is ON, an interrupt can cause the switch to connect the RFID circuit to the single antenna, sometimes only for less than a predetermined duration.

Abstract: An electronic device (100) includes a control circuit (108) that is operable with a memory or storage device (120). The electronic device includes an RFID tag (113) having a second memory (118). The RFID tag can be read from, or written to, by a RFID communication device (114) when the electronic device is OFF. Device personalization can be achieved when the control circuit accesses the second memory to retrieve the device configuration data during a boot sequence and configures the electronic device in accordance with the device configuration data retrieved from the second memory during the boot sequence. Device information can be made available when the electronic device is OFF by writing the device information to the second memory.

Abstract: An electronic device (100) includes a control circuit (108) that is operable with a memory or storage device (120). The electronic device includes an RFID tag (113) having a second memory (118). The RFID tag can be read from, or written to, by a RFID communication device (114) when the electronic device is OFF. Device personalization can be achieved when the control circuit accesses the second memory to retrieve the device configuration data during a boot sequence and configures the electronic device in accordance with the device configuration data retrieved from the second memory during the boot sequence. Device information can be made available when the electronic device is OFF by writing the device information to the second memory.

Abstract: The present invention relates to stable compositions comprising linaclotide, as well as to various methods and processes for the preparation and use of the compositions.

Abstract: Various embodiments provide materials and methods for a superoleophobic device, which can include a conformal oleophobic coating disposed on glass pillars and/or stripe-shaped glass structures on a glass substrate to provide the device with a textured superoleophobic surface.

Abstract: A mobile device includes a touch screen display and touch screen circuit for receiving touch inputs. A camera configured to acquire one or more images in front of the display. A proximity sensor configured to provide an indication that a user is in close proximity to the touch screen display. A processor being effective to determine, in response to the indication of the proximity sensor, whether the user is in a position to view the display based on the one or more images of the camera. If the proximity sensor provides an indication that the user is in close proximity to the display and the processor determines, based on the one or more images, that the user is in a position to view the display, then at least one of the display and the touch screen circuit are not disabled.