Patents by Inventor Hong Zhong
Hong Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11948333Abstract: A disparity image fusion method for multiband stereo cameras belongs to the field of image processing and computer vision. The method obtains pixel disparity confidence information by using the intermediate output of binocular disparity estimation. The confidence information can be used to judge the disparity credibility of the position and assist disparity fusion. The confidence acquisition process makes full use of the intermediate output of calculation, and can be conveniently embedded into the traditional disparity estimation process, with high calculation efficiency and simple and easy operation. In the disparity image fusion method for multiband stereo cameras proposed by the method, the disparity diagrams participating in the fusion are obtained according to the binocular images of the corresponding bands, which makes full use of the information of each band and simultaneously avoiding introducing uncertainty and errors.Type: GrantFiled: March 5, 2020Date of Patent: April 2, 2024Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, PENG CHENG LABORATORYInventors: Wei Zhong, Hong Zhang, Haojie Li, Zhihui Wang, Risheng Liu, Xin Fan, Zhongxuan Luo, Shengquan Li
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Publication number: 20240066138Abstract: Provided herein are antibody-drug conjugates, for example, a compound of Formula (I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.Type: ApplicationFiled: December 22, 2021Publication date: February 29, 2024Inventors: Hong Fu, Ziyang Zhong
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Publication number: 20220056422Abstract: An application of a UTX gene in preparation of drugs for preventing or treating lipid diseases. The invention further discloses a method for knocking out a UTX gene from a mouse liver. The invention further discloses a UTX overexpression adenovirus as well as a preparation method and an application thereof. The invention further discloses a method for upregulating UTX expression in a mouse liver. The invention further discloses therapeutic action of UTX overexpression on HFD induced hyperlipidemia and NAFLD. The invention provides an available laboratory basis for preparing lipid-lowering drugs, so that the UTX can be used for preparing drugs affecting the lipid, and a new research method is provided for researching the occurrence and development of dyslipidemia.Type: ApplicationFiled: October 28, 2021Publication date: February 24, 2022Inventors: Chenbo JI, Ling CHEN, Xirong GUO, Hong ZHONG
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Publication number: 20210276023Abstract: An alkyl thioether ethyl hydroxamic acid beneficiation reagent and a preparation method and application thereof are provided. The alkyl thioether ethyl hydroxamic acid molecules have two functional groups, a thioether group and a hydroxamate group. The beneficiation reagent is obtained by esterification of alkyl thioether acetic acid and methanol and then by hydroxamation of hydroxylamine and an alkali. The alkyl thioether ethyl hydroxamic acid beneficiation reagent can be used as a collector for mineral flotation. The preparation method is simple and has a high yield. The thioether and hydroxamate group in the molecules have a synergistic effect and can effectively improve the collection performance.Type: ApplicationFiled: June 19, 2020Publication date: September 9, 2021Applicant: CENTRAL SOUTH UNIVERSITYInventors: Hong ZHONG, Qing SUN, Shuai WANG
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Patent number: 11033844Abstract: Stabilized air filters formed from mats of crosslinked protein-containing fibers are provided. The fibers are formed into a mat with pores that allow air to pass through while physically filtering particulate matter. The protein in the protein-containing fibers also serves to chemically filter polluted air passed through the filter. Specifically, chemical functional groups from the many amino acids that comprise the protein of the protein-containing nanowire react with certain chemical pollutants (e.g., carbon monoxide and formaldehyde) in order to capture or otherwise neutralize the pollutant. Accordingly, the single fiber mat performs two filtering functions. Methods for making the air filters from crosslinked protein-containing nanofibers are also provided.Type: GrantFiled: May 1, 2018Date of Patent: June 15, 2021Assignee: Washington State UniversityInventors: Wei-Hong Zhong, Hamid Souzandeh, Yu Wang
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Patent number: 10913863Abstract: The present disclosure provides a cesium tungsten bronze-based self-cleaning nano heat-insulation coating material, and method of preparing the same. Cesium tungsten bronze nanoparticles are prepared by hydrothermal method using WCl6 and CsOH.5H2O as raw materials, PVP as a surfactant and acetic acid as an acid catalyst. TiO2 nanoparticles are prepared from TiCl4. Subsequently ball milling and dispersing of the cesium tungsten bronze nanoparticles, the TiO2 nanoparticles, and a silane coupling agent with water to obtain an aqueous slurry containing cesium tungsten bronze/TiO2 composite particles is performed. The concentration of the aqueous slurry containing cesium tungsten bronze/TiO2 composite particles is adjusted to obtain a self-cleaning nano heat-insulation coating material.Type: GrantFiled: March 1, 2018Date of Patent: February 9, 2021Assignee: The Hong Kong Polytechnic UniversityInventors: Lin Lu, Yuanhao Wang, Hong Zhong, Yan Hu
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METHOD FOR PREPARING THIONOCARBAMATE AND CO-PRODUCING 2-MERCAPTOETHANOL OR O-ALKYLTHIOETHYL XANTHATE
Publication number: 20210002218Abstract: The invention belongs to the field of mineral flotation collector materials, and particularly discloses a method for preparing thionocarbamate. In the preparation process, xanthate and 2-haloethanol are esterified to obtain O-alkyl-S-hydroxyethyl xanthate, and then O-alkyl-S-hydroxyethyl xanthate and fatty amine are reacted to obtain a mixture of thionocarbamate and 2-mercaptoethanol. The mixture of thionocarbamate and 2-mercaptoethanol is washed with alkali, and the oil phase and water phase are separated. The oil phase and water phase are thionocarbamate and 2-hydroxyethylthiolate, respectively, and 2-mercaptoethanol is obtained by washing with an acid. 2-alkylthioethanol is obtained by reacting 2-hydroxyethanethiolate with alkyl halide, and then with carbon disulfide and alkali to prepare O-alkylthioethyl xanthate. Thionocarbamate, 2-mercaptoethanol and O-alkylthioethyl xanthate prepared by this method possess high yield and high purity.Type: ApplicationFiled: December 7, 2018Publication date: January 7, 2021Applicant: CENTRAL SOUTH UNIVERSITYInventors: Hong ZHONG, Xiaoping HUANG, Shuai WANG, Zhanfang CAO -
Publication number: 20200392080Abstract: A method for preparing xanthate by a slurry method includes steps of: adding a mixture of dichloromethane and carbon disulfide as a reaction solvent in a slurry reactor, and then adding alcohol and caustic alkali to react with carbon disulfide under less than 1 atm to remove heat released by the reaction by evaporating the solvent; performing vacuum distillation after the reaction to remove the solvent and water, so as to obtain the xanthate; transporting the xanthate to a granulation equipment for granulating, and then drying in a drying equipment to obtain a product. The method is performed in a system formed by a reaction equipment, a solvent recovery equipment, the granulation equipment, and the drying equipment, wherein a main equipment of the reaction system is a slurry reactor. The method has advantages of high efficiency, low energy consumption, good safety, environmental friendliness, convenient operation and the like.Type: ApplicationFiled: August 28, 2020Publication date: December 17, 2020Inventors: Hong Zhong, Xin Ma, Shuai Wang
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Patent number: 10737280Abstract: The present invention relates to an azolethione flotation collector and application thereof. According to the application, an azolethione compound such as a 1,3,4-thiadiazole-2-thione compound, a 1,3,4-oxadiazole-2-thione compound, a 1,2,4-triazole-3-thione compound or a 1,2,4,5-tetrazole-3-thione compound is used as a mineral flotation collector to be applied to ores containing copper, zinc, lead, nickel, cobalt, platinum, palladium, silver or gold minerals to realize flotation recovery of valuable metal minerals. Compared with common flotation collectors in the existing technologies, the flotation collector of the present invention can effectively improve enrichment and recovery of copper, zinc, lead, nickel, cobalt, platinum, palladium, silver or gold minerals.Type: GrantFiled: March 21, 2019Date of Patent: August 11, 2020Assignee: CENTRAL SOUTH UNIVERSITYInventors: Guangyi Liu, Yaoguo Huang, Longqun Ma, Xiaoxue Niu, Jun Liu, Hong Zhong, Zhe Hu
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Publication number: 20200024580Abstract: An application of a UTX gene in preparation of drugs for preventing or treating lipid diseases. The invention further discloses a method for knocking out a UTX gene from a mouse liver. The invention further discloses a UTX overexpression adenovirus as well as a preparation method and an application thereof. The invention further discloses a method for upregulating UTX expression in a mouse liver. The invention further discloses therapeutic action of UTX overexpression on HFD induced hyperlipidemia and NAFLD. The invention provides an available laboratory basis for preparing lipid-lowering drugs, so that the UTX can be used for preparing drugs affecting the lipid, and a new research method is provided for researching the occurrence and development of dyslipidemia.Type: ApplicationFiled: August 28, 2019Publication date: January 23, 2020Inventors: Chenbo JI, Ling CHEN, Xirong GUO, Hong ZHONG
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Patent number: 10525398Abstract: Air filters formed from mats of protein-containing nanowires are provided. The nanowires are formed into a mat with pores that allow air to pass through while physically filtering particulate matter. The protein in the protein-containing nanowires also serves to chemically filter polluted air passed through the filter. Specifically, chemical functional groups from the many amino acids that comprise the protein of the protein-containing nanowire react with certain chemical pollutants (e.g., carbon monoxide and formaldehyde) in order to capture or otherwise neutralize the pollutant. Accordingly, the single nanofiber mat performs two filtering functions. Methods of filtering air using the provided air filters are also disclosed, as well as methods for making the air filters from protein-containing nanofibers.Type: GrantFiled: March 29, 2018Date of Patent: January 7, 2020Assignee: Washington State UniversityInventors: Wei-hong Zhong, Hamid Souzandeh, Yu Wang
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Patent number: 10364141Abstract: Block copolymer nanostructures such as nanosheets, nanoribbons, and nanotubes, are provided. The nanotructures are formed by the self-assembly of block copolymers during evaporation of solvent from a sol that has been “disturbed”, either i) internally by the introduction of relief (e.g. curvature) and/or the inclusion of nanoparticles in the sol; or ii) externally, e.g. by physical deformation of a semi-solid form of the sol, or a combination of internal and external disturbance. The nanostructures have uses in, for example, energy devices, electronics, sensors and drug delivery applications.Type: GrantFiled: December 18, 2014Date of Patent: July 30, 2019Assignee: WASHINGTON STATE UNIVERSITYInventors: Yu Wang, Wei-hong Zhong
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Publication number: 20190217310Abstract: The present invention relates to an azolethione flotation collector and application thereof. According to the application, an azolethione compound such as a 1,3,4-thiadiazole-2-thione compound, a 1,3,4-oxadiazole-2-thione compound, a 1,2,4-triazole-3-thione compound or a 1,2,4,5-tetrazole-3-thione compound is used as a mineral flotation collector to be applied to ores containing copper, zinc, lead, nickel, cobalt, platinum, palladium, silver or gold minerals to realize flotation recovery of valuable metal minerals. Compared with common flotation collectors in the existing technologies, the flotation collector of the present invention can effectively improve enrichment and recovery of copper, zinc, lead, nickel, cobalt, platinum, palladium, silver or gold minerals.Type: ApplicationFiled: March 21, 2019Publication date: July 18, 2019Applicant: CENTRAL SOUTH UNIVERSITYInventors: Guangyi LIU, Yaoguo HUANG, Longqun MA, Xiaoxue NIU, Jun LIU, Hong ZHONG, Zhe HU
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Publication number: 20180340082Abstract: The present disclosure provides a cesium tungsten bronze-based self-cleaning nano heat-insulation coating material, and method of preparing the same. Cesium tungsten bronze nanoparticles are prepared by hydrothermal method using WCl6 and CsOH.5H2O as raw materials, PVP as a surfactant and acetic acid as an acid catalyst. TiO2 nanoparticles are prepared from TiCl4. Subsequently ball milling and dispersing of the cesium tungsten bronze nanoparticles, the TiO2 nanoparticles, and a silane coupling agent with water to obtain an aqueous slurry containing cesium tungsten bronze/TiO2 composite particles is performed. The concentration of the aqueous slurry containing cesium tungsten bronze/TiO2 composite particles is adjusted to obtain a self-cleaning nano heat-insulation coating material.Type: ApplicationFiled: March 1, 2018Publication date: November 29, 2018Applicant: The Hong Kong Polytechnic UniversityInventors: Lin LU, Yuanhao WANG, Hong ZHONG, Yan HU
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Publication number: 20180311599Abstract: Stabilized air filters formed from mats of crosslinked protein-containing fibers are provided. The fibers are formed into a mat with pores that allow air to pass through while physically filtering particulate matter. The protein in the protein-containing fibers also serves to chemically filter polluted air passed through the filter. Specifically, chemical functional groups from the many amino acids that comprise the protein of the protein-containing nanowire react with certain chemical pollutants (e.g., carbon monoxide and formaldehyde) in order to capture or otherwise neutralize the pollutant. Accordingly, the single fiber mat performs two filtering functions. Methods for making the air filters from crosslinked protein-containing nanofibers are also provided.Type: ApplicationFiled: May 1, 2018Publication date: November 1, 2018Applicant: Washington State UniversityInventors: Wei-Hong Zhong, Hamid Souzandeh, Yu Wang
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Publication number: 20180214813Abstract: Air filters formed from mats of protein-containing nanowires are provided. The nanowires are formed into a mat with pores that allow air to pass through while physically filtering particulate matter. The protein in the protein-containing nanowires also serves to chemically filter polluted air passed through the filter. Specifically, chemical functional groups from the many amino acids that comprise the protein of the protein-containing nanowire react with certain chemical pollutants (e.g., carbon monoxide and formaldehyde) in order to capture or otherwise neutralize the pollutant. Accordingly, the single nanofiber mat performs two filtering functions. Methods of filtering air using the provided air filters are also disclosed, as well as methods for making the air filters from protein-containing nanofibers.Type: ApplicationFiled: March 29, 2018Publication date: August 2, 2018Applicant: Washington State UniversityInventors: Wei-hong Zhong, Hamid Souzandeh, Yu Wang
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Patent number: 9614250Abstract: Various embodiments of solid-state conductors containing solid polymer electrolytes, electronic devices incorporating the solid-sate conductors, and associated methods of manufacturing are described herein. In one embodiment, a solid-state conductor includes poly(ethylene oxide) having molecules with a molecular weight of about 200 to about 8×106 gram/mol, and a soy protein product mixed with the poly(ethylene oxide), the soy protein product containing glycinin and ?-conglycinin and having a fine-stranded network structure. Individual molecules of the poly(ethylene oxide) are entangled in the fine-stranded network structure of the soy protein product, and the poly(ethylene oxide) is at least 50 % amorphous.Type: GrantFiled: March 24, 2014Date of Patent: April 4, 2017Assignee: Empire Technology Development LLCInventors: Wei-Hong Zhong, Jianying Ji, Bin Li
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Finite fully addressable nucleic acid nanostructures as nanocarriers for delivery of pharmaceuticals
Patent number: 9579396Abstract: The present invention provides nanostructures that are particularly well suited for delivery of bioactive agents to organs, tissues, and cells of interest in vivo, and for diagnostic purposes. In exemplary embodiments, the nanostructures are complexes of DNA strands having fully defined nucleotide sequences that hybridize to each other in such a way as to provide a pre-designed three dimensional structure with binding sites for targeting molecules and bioactive agents. The nanostructures are of a pre-designed finite length and have a pre-defined three dimensional structure.Type: GrantFiled: May 4, 2012Date of Patent: February 28, 2017Assignee: PARABON NANOLABS, INC.Inventors: Chris Dwyer, Hong Zhong, Michael Norton, Steven Armentrout -
Publication number: 20160332869Abstract: Block copolymer nanostructures such as nanosheets, nanoribbons, and nanotubes, are provided. The nanotructures are formed by the self-assembly of block copolymers during evaporation of solvent from a sol that has been “disturbed”, either i) by the introduction of relief (e.g. curvature) and/or the inclusion of nanoparticles in the sol; or ii) externally, e.g. by physical deformation of a semi-solid form of the sol, or a combination of internal and external disturbance. The nanostructures have uses in, for example, energy devices, electronics, sensors and drug delivery applications.Type: ApplicationFiled: December 18, 2014Publication date: November 17, 2016Inventors: Yu WANG, Wei-hong ZHONG
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Patent number: D930579Type: GrantFiled: August 3, 2018Date of Patent: September 14, 2021Assignee: GUANG ZHOU YUN ZHONG CAI TECHNOLOGY CO., LTD.Inventor: Cai-Hong Zhong