Patents by Inventor Hongbo Liu
Hongbo Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150225764Abstract: A method for simultaneously measuring the activities of multiple kinds of enzymes in single channel through concimitantly monitoring multiple wavelength absorbances is claimed; based on linear additivity of absorbances and the isoabsorbance wavelengths of chromogenic substrates and their chromogenic products, both the principles for the combination of chromogenic substrates required for simultaneously measuring the activities of multiple kinds of enzymes in single channel through concimitantly monitoring multiple wavelength absorbances and an approach for data processing to eliminate the interference of the overlapped absorbances are developed, kinetic analysis of reaction curves via numerical integration eliminates the interference of all substrates and products and estimates the maximal reaction rates of the enzymes to be measured, giving the linear ranges and the limits of quantification for simultaneously measuring the activities of multiple kinds of enzymes in single channel comparable to those by separaType: ApplicationFiled: September 24, 2012Publication date: August 13, 2015Applicant: Chongqing Medical UniversityInventors: Fei Liao, Xiaolan Yang, Hongbo Liu, Jizheng Dang, Gaobo Long, Yuanli Li, Lin Liu
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Publication number: 20140304942Abstract: A concealed door closer includes a housing, an input shaft and an output shaft, the input shaft being connected to a motor, wherein a joining member is arranged between the input shaft and the output shaft, and two ends of the joining member are respectively provided with an upper connection piece and a lower connection piece, which are connected to a roller via vertical rotation shaft, and wherein both the input shaft and the output shaft are provided with a left connection piece and a right connection piece, which are horizontally connected to the roller via a horizontal rotation shaft. The components in the door closer have a simple structure and may be easily processed and assembled. The size of the joint after assembly is equivalent to that of the joining member, so the overall size is small.Type: ApplicationFiled: March 13, 2014Publication date: October 16, 2014Applicant: Oubao Security Technology Co., Ltd.Inventors: Haojie LI, Zhenfeng FU, Guowei JIANG, Zhenbo WU, Hongbo LIU, Weibin LAN, Chenxi ZHU, Jun ZHANG, Maochen ZHANG
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Publication number: 20140284404Abstract: Disclosed is a chemical vapour deposition injector 100, comprising a gas injector body 104 having a plurality of holes for directing a first gas from a first gas plenum into respective first gas channels of the gas injector body, each first gas channel extending in a first direction and arranged to branch into separate flow paths; a plurality of discrete first conduits, each first conduit being arranged to connect to a respective one of the discrete flow paths for carrying the first gas to a reaction chamber; a second gas channel for directing a second gas from a second gas plenum into the gas injector body, the second gas channel having a longitudinal axis which extends in a second direction transverse to the first direction; and a plurality of discrete second conduits coupled to the second gas channel and arranged to carry the second gas from the second gas channel to the reactor chamber; wherein at least some of the discrete second conduits are arranged between the discrete first conduits.Type: ApplicationFiled: March 20, 2013Publication date: September 25, 2014Applicant: ASM Technology Singapore Pte Ltd.Inventors: Teng Hock KUAH, Hongbo LIU, Jiuan WEI, Wentao WANG, Jingsheng CHEN, Jiapei DING, Ravindra RAGHAVENDRA, Bubesh Babu JOTHEESWARAN, Meer Saiful HASSAN
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Patent number: 8475825Abstract: The present invention is directed to curable compositions that comprise a non-porous substrate, one or more cyanoacrylate polymerization initiators and a prepolymer composition comprising at least one liquid cyanoacrylate monomer or mixture of such monomers (solid or liquid) and/or cyanoacrylate oligomers. The non-porous substrate is a collection of individual particulates that are not bound, bonded or fixed to one another. At least one initiator is deposited on the surface of the individual particulates to form a plurality of initiator carriers. The prepolymer composition receives the plurality of initiator carriers to begin a controlled and consistent polymerization or curing of the liquid cyanoacrylate monomer in order to produce a biocompatible adhesive composition for use on living tissue. The present invention also provides for methods of making and using and devices for such a curable compositions, particularly in treating living tissue by applying to living tissue a biocompatible adhesive composition.Type: GrantFiled: May 25, 2010Date of Patent: July 2, 2013Assignee: Ethicon, Inc.Inventor: Hongbo Liu
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Patent number: 8412364Abstract: A method and a device for sending and playing the streaming data are disclosed in embodiments of the present invention. The method for playing the streaming data includes: receiving the streaming data from the client and buffering the data; and exporting the buffered streaming data according to the predefined rhythm. The statistics about the streaming data in the buffer is collected; and the rhythm is adjusted according to the amount of streaming data. The transmitting end can send the streaming data to the client as soon as possible and buffer only a little data; the client controls the rhythm to reduce the effect of network jitter on delay, thus shortening the delay of streaming play.Type: GrantFiled: December 18, 2009Date of Patent: April 2, 2013Assignee: Huawei Technologies Co., Ltd.Inventors: Zhaozao Li, Hongbo Liu, Shen Qu
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Publication number: 20110230561Abstract: A medical adhesive composition comprising, based upon the total weight of the composition, from about 50 wt. % to about 99.9 wt. % of one or more ?-cyanoacrylate monomers and from about 0.1 wt. % to about 5 wt. % of one or more non-steroidal anti-inflammatory drugs (NSAIDs). Suitable NSAIDs include ibuprofen and acetaminophen. The resulting compositions provide enhances fibroblast proliferation and reduced cytotoxicity compared to compositions that do not contain NSAID.Type: ApplicationFiled: November 17, 2009Publication date: September 22, 2011Inventors: Hongbo Liu, Sandra Gonzalez, Breda Mary Cullen, Derek Walter Silcock
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Publication number: 20110105225Abstract: A device for positioning a playing video is provided. The device includes: a receiving engine, configured to generate a control signal according to a user instruction; and a user interface engine, configured to respond to the control signal from the receiving engine, define a display interface, present a video playing progress indicator on the display interface according to the control signal, and adjust a scale of the video playing progress indicator to determine a display range of the playing video. Meanwhile, a method and a system for positioning a playing video are provided. A video playing progress indicator is presented on a display interface according to a control signal, and a play scale of the progress indicator is adjusted to determine a display range of the playing video, so as to enhance flexibility in the detailed operation of a video progress.Type: ApplicationFiled: October 25, 2010Publication date: May 5, 2011Inventors: Yasong Huang, Hongbo Liu, Zhaozao Li
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Patent number: 7919480Abstract: An antimicrobial composition comprising: a complex of a polysaccharide covalently bonded with an antibiotic. A medical device having an antimicrobial composition comprising: a complex of an oxidized regenerated cellulose covalently bonded with gentamicin.Type: GrantFiled: May 3, 2007Date of Patent: April 5, 2011Assignee: Ethicon, Inc.Inventors: Hongbo Liu, Xintian Ming
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Publication number: 20100330027Abstract: The present invention is directed to curable compositions that comprise a non-porous substrate, one or more cyanoacrylate polymerization initiators and a prepolymer composition comprising at least one liquid cyanoacrylate monomer or mixture of such monomers (solid or liquid) and/or cyanoacrylate oligomers. The non-porous substrate is a collection of individual particulates that are not bound, bonded or fixed to one another. At least one initiator is deposited on the surface of the individual particulates to form a plurality of initiator carriers. The prepolymer composition receives the plurality of initiator carriers to begin a controlled and consistent polymerization or curing of the liquid cyanoacrylate monomer in order to produce a biocompatible adhesive composition for use on living tissue. The present invention also provides for methods of making and using and devices for such a curable compositions, particularly in treating living tissue by applying to living tissue a biocompatible adhesive composition.Type: ApplicationFiled: May 25, 2010Publication date: December 30, 2010Inventor: Hongbo Liu
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Publication number: 20100168885Abstract: A method and a device for sending and playing the streaming data are disclosed in embodiments of the present invention. The method for playing the streaming data includes: receiving the streaming data from the client and buffering the data; and exporting the buffered streaming data according to the predefined rhythm. The statistics about the streaming data in the buffer is collected; and the rhythm is adjusted according to the amount of streaming data. The transmitting end can send the streaming data to the client as soon as possible and buffer only a little data; the client controls the rhythm to reduce the effect of network jitter on delay, thus shortening the delay of streaming play.Type: ApplicationFiled: December 18, 2009Publication date: July 1, 2010Applicant: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Zhaozao Li, Hongbo Liu, Shen Qu
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Patent number: 7713544Abstract: A biocompatible biological component is provided comprising a membrane-mimetic surface film covering a substrate. Suitable substrates include hydrated substrates, e.g. hydrogels which may contain drugs for delivery to a patient through the membrane-mimetic film, or may be made up of cells, such as islet cells, for transplantation. The surface may present exposed bioactive molecules or moieties for binding to target molecules in vivo, for modulating host response when implanted into a patient (e.g. the surface may be antithrombogenic or antiinflammatory) and the surface may have pores of selected sizes to facilitate transport of substances therethrough. An optional hydrophilic cushion or spacer between the substrate and the membrane-mimetic surface allows transmembrane proteins to extend from the surface through the hydrophilic cushion, mimicking the structure of naturally-occurring cells.Type: GrantFiled: July 30, 2001Date of Patent: May 11, 2010Assignee: Emory UniversityInventors: Elliot L. Chaikof, June Feng, Janine M. Orban, Hongbo Liu, Xue Long Sun, Keith M. Faucher
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Publication number: 20100051813Abstract: A measurement accessory with multiple transmission-reflections uses for an infrared spectrometer, laid accessory is arranged in the sample cavity of the infrared spectrometer. Said accessory includes two parallel plane mirrors (7, 8) and a sample holder fixed between the two mirrors (7, 8). Said sample holder can fix the sample piece (9) between the two plane mirrors (7, 8) and make the sample piece parallel with plane mirrors (7, 8). During measuring, the infrared ray emitted from infrared spectrometer (17) forms a certain angle incident to the space between said plane mirrors and reflects for several times between the two parallel plane mirrors (7, 8) and the sample piece (9) is measured with multiple transmission-reflections by the infrared spectrometer. Then the infrared spectrometer (20) enters into the detector of infrared spectrometer.Type: ApplicationFiled: November 12, 2007Publication date: March 4, 2010Applicant: NANJING UNIVERSITYInventors: Shoujun Xiao, Hongbo Liu
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Patent number: 7534907Abstract: A monomer composition comprising at least one polymerizable alkyl ester ?-cyanoacrylate monomer. Specifically, the ?-cyanoacrylate monomer is an alkyl ester ?-cyanoacrylate monomer of the general formula having a spacer R1: n is from 2 to 12; R3 and R4 are each an alkyl group or a hydrogen, and at least one of R3 or R4 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; R2 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; and the combined number of carbon atoms (N) in the spacer R1 is at least n+1.Type: GrantFiled: May 30, 2007Date of Patent: May 19, 2009Assignee: Ethichon, Inc.Inventor: Hongbo Liu
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Publication number: 20090075283Abstract: The present invention relates to a shuttle BAC vector for facilitating the cloning, transfer and heterologous expression of streptomycete secondary metabolite biosynthetic gene clusters. The invention also relates to a plasmid rescue method using this vector for enhancing the process of cloning biosynthetic gene clusters for secondary metabolites from streptomycetes without sophisticated generation and screening of cosmids or BAC libraries. The cloned DNA can then be used for sequencing or heterologous expression of putative secondary metabolic gene clusters.Type: ApplicationFiled: July 25, 2008Publication date: March 19, 2009Applicant: WyethInventors: Hongbo Liu, Min He
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Publication number: 20080275230Abstract: An antimicrobial composition comprising: a complex of a polysaccharide covalently bonded with an antibiotic. A medical device having an antimicrobial composition comprising: a complex of an oxidized regenerated cellulose covalently bonded with gentamicin.Type: ApplicationFiled: May 3, 2007Publication date: November 6, 2008Inventors: Hongbo Liu, Xintian Ming
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Publication number: 20070224163Abstract: A monomer composition comprising at least one polymerizable alkyl ester ?-cyanoacrylate monomer. Specifically, the ?-cyanoacrylate monomer is an alkyl ester ?-cyanoacrylate monomer of the general formula having a spacer R1: n is from 2 to 12; R3 and R4 are each an alkyl group or a hydrogen, and at least one of R3 or R4 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; R2 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; and the combined number of carbon atoms (N) in the spacer R1 is at least n+1.Type: ApplicationFiled: May 30, 2007Publication date: September 27, 2007Inventor: Hongbo Liu
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Publication number: 20070213553Abstract: A method for producing a cyanoacrylate monomer, comprising the steps of (a) reacting cyanoacetate and formaldehyde or paraformaldehyde in the presence of a base or amine base catalyst to form an ?-cyanoacrylate prepolymer or oligomer mixture; (b) subjecting the ?-cyanoacrylate prepolymer or oligomer mixture to a substrate having free acid, acid derivative, or free aldehyde or ketone groups to remove the catalyst and to obtain a purified ?-cyanoacrylate prepolymer or oligomer; and (c) subjecting the purified ?-cyanoacrylate prepolymer or oligomer to depolymerization to obtain an ?-cyanoacrylate monomer.Type: ApplicationFiled: March 10, 2006Publication date: September 13, 2007Inventors: Hongbo Liu, Sandra Gonzalez
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Patent number: 7238828Abstract: A monomer composition comprising at least one polymerizable alkyl ester ?-cyanoacrylate monomer. Specifically, the ?-cyanoacrylate monomer is an alkyl ester ?-cyanoacrylate monomer of the general formula having a spacer R1: wherein n is from 2 to 12; R3 and R4 are each an alkyl group or a hydrogen, and at least one of R3 or R4 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; R2 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; and the combined number of carbon atoms (N) in the spacer R1 is at least n+1.Type: GrantFiled: March 24, 2005Date of Patent: July 3, 2007Assignee: Ethicon, Inc.Inventor: Hongbo Liu
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Publication number: 20060216266Abstract: A monomer composition comprising at least one polymerizable alkyl ester ?-cyanoacrylate monomer. Specifically, the ?-cyanoacrylate monomer is an alkyl ester ?-cyanoacrylate monomer of the general formula having a spacer R1: wherein n is from 2 to 12; R3 and R4 are each an alkyl group or a hydrogen, and at least one of R3 or R4 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; R2 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; and the combined number of carbon atoms (N) in the spacer R1 is at least n+1.Type: ApplicationFiled: March 24, 2005Publication date: September 28, 2006Inventor: Hongbo Liu
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Patent number: 6936298Abstract: The present Specification describes materials and methods which provide for improved performance of medical prostheses, including vascular graft material, artificial heart valves, and other implanted materials. The materials comprising bound thrombomodulin or a functionally equivalent derivative protein, provide for fewer undesirable side effects including inflammation, thromboses and neointimal hyperplasia.Type: GrantFiled: April 13, 2001Date of Patent: August 30, 2005Assignee: Emory UniversityInventors: Elliot L. Chaikof, June Feng, Janine M. Orban, Hongbo Liu, Xue-Long Sun