Patents by Inventor Hongbo Zhang

Hongbo Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210218831
    Abstract: A TOE component obtains a first storage address, where the first storage address is an address of a first storage block in a memory, the first storage block stores a target TCP packet, and the target TCP packet includes a packet header and a TCP payload. The TOE component obtains the packet header from the first storage block based on the first storage address. The TOE component performs TCP-related protocol processing based on the packet header, where the TCP payload is not read out of the first storage block by the TOE component when the TOE component performs TCP-related protocol processing based on the packet header.
    Type: Application
    Filed: March 26, 2021
    Publication date: July 15, 2021
    Inventors: Qikun Wei, Mingli Zhang, Yanfei Han, Hongbo Zhao
  • Patent number: 11013694
    Abstract: The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: May 25, 2021
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Xiaobing Sun, Shunnan Zhang, Zhengliang Ye, Hai'ou Dong, Hongbo Zhang, Wensheng Zhang, Lihong Zhou, Chenming Li, Cong Chen, Xiaofeng Liu, Shiqing Wang, Changsheng Rong, Yongfeng Zheng, Lijun Fan
  • Publication number: 20210137959
    Abstract: The present invention relates to agents that induce mitochondrial unfolded protein response (UPRmt) in muscle stem cells and prevents or reverse process of muscle stem cell senescence. Further, the invention relates to methods and compositions useful in the prevention and/or treatment of muscle stem senescence.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 13, 2021
    Inventors: HONGBO ZHANG, KEIR MENZIES, JOHAN AUWERX, DONGRYEOL RYU
  • Publication number: 20210130239
    Abstract: The present invention discloses a high-strength prestressed composite ceramic and a preparation method thereof, and belongs to a ceramic reinforcing technology in the field of high-performance structural ceramics. Firstly, more than two kinds of bondable ceramics need to be determined to form a composite ceramic of a matrix material and a surface layer material, the matrix material should have sufficient strength and a higher expansion coefficient, and the surface layer material should have a lower expansion coefficient and a higher elastic modulus, realizing the balance of the surface layer compressive stress and the matrix tensile stress are formed after high-temperature co-sintering; and the surface layer compressive stress can greatly improve the bending strength of the composite ceramic.
    Type: Application
    Filed: August 22, 2020
    Publication date: May 6, 2021
    Inventors: Yiwang BAO, Fenghua KUANG, Hongbo ZHANG, Detian WAN
  • Patent number: 10980809
    Abstract: The present invention relates to a urea-substituted aromatic ring-linked dioxinoquinazoline and a urea-substituted aromatic ring-linked dioxinoquinoline of Formula (I), or a pharmaceutically acceptable salt thereof or a hydrate thereof. Also provided are the preparation of the compound as shown in Formula (I) and the pharmaceutically acceptable salt thereof and the use thereof as a drug. The drug is used as an inhibitor of tyrosine kinases (e.g., VEGFR-2, C-RAF, B-RAF) for treating tyrosine kinase-related diseases.
    Type: Grant
    Filed: February 11, 2018
    Date of Patent: April 20, 2021
    Assignee: BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
    Inventors: Qiang Zhang, Hongbo Zhang, Leifu Yang, Hailong Yang, Likai Zhou, Nanqiao Zheng, Shannan Yu, Zhongxiang Wang, Shouye Feng, Zhanqiang Xu
  • Publication number: 20210040114
    Abstract: Provided are an oxazino-quinazoline and oxazino-quinoline type compound, a preparation method, and uses thereof. More particularly provided is a compound shown in formula (I), an isomer, a hydrate, a solvate, a pharmaceutically acceptable salt, a prodrug thereof, a preparation method, and uses thereof in preparing a drug acting as a kinase inhibitor.
    Type: Application
    Filed: March 5, 2019
    Publication date: February 11, 2021
    Inventors: Qiang Zhang, Shannan Yu, Zhongxiang Wang, Shouye Feng, Nanqiao Zheng, Hailong Yang, Leifu Yang, Hongbo Zhang, Likai Zhou, Zhanqiang Xu
  • Patent number: 10905704
    Abstract: The present invention relates to agents that induce mitochondrial unfolded protein response (UPR mt) in muscle stem cells and prevents or reverse process of muscle stem cell senescence. Further, the invention relates to methods and compositions useful in the prevention and/or treatment of muscle stem senescence.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: February 2, 2021
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Hongbo Zhang, Keir Menzies, Johan Auwerx, Dongryeol Ryu
  • Patent number: 10896029
    Abstract: The disclosure relates to a method for constructing a graph data structure as an intermediate representation of source code for a compiler configured for compiling the source code into executable machine code running on a processor of a computer system, wherein program operations of the source code are represented in an object-oriented programming language by objects of classes that form a hierarchy growing from a base node class of the graph data structure, the method comprising: producing new nodes of the graph data structure by calling factory methods associated with existing nodes of the graph data structure based on a factory method design pattern implemented in the nodes of the graph data structure, wherein the nodes of the graph data structure are identified by symbols; and using the symbols as proxies of the nodes of the graph data structure according to a proxy design pattern.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: January 19, 2021
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Alexander Vladimirovich Slesarenko, Anton Yurievich Orlov, Hongbo Zhang
  • Publication number: 20200399284
    Abstract: The present invention relates to an urea-substituted aromatic ring-linked dioxinoquinoline compound of formula (I), or a pharmaceutically acceptable salt or a hydrate thereof. The invention also provides a preparation method of the compound of formula (I) and a pharmaceutically acceptable salt thereof, as well as uses thereof as a drug, wherein the drug acting as a tyrosine kinase (i.e. VEGFR-2, C-RAF, B-RAF, and RET) inhibitor is used for treating disorders related to tyrosine kinase.
    Type: Application
    Filed: January 25, 2019
    Publication date: December 24, 2020
    Inventors: Qiang Zhang, Shannan Yu, Zhongxiang Wang, Shouye Feng, Yansheng Liu, Xingfu Li, Hongbo Zhang, Leifu Yang, Hailong Yang, Likai Zhou, Nanqiao Zheng, Chenming Hu, Zhanqiang Xu
  • Publication number: 20200399285
    Abstract: The present invention relates to a dioxinoquinoline compound of formula (I) or a pharmaceutically acceptable salt thereof. The invention also provides a preparation method of the compound of formula (I) and a pharmaceutically acceptable salt thereof, as well as uses thereof as a drug, wherein the drug acting as a tyrosine kinase (i.e. VEGFR-2 and c-MET) inhibitor is used for treating disorders related to tyrosine kinase.
    Type: Application
    Filed: January 25, 2019
    Publication date: December 24, 2020
    Inventors: Qiang Zhang, Shannan Yu, Zhongxiang Wang, Shouye Feng, Yueming Sun, Yansheng Liu, Hongbo Zhang, Leifu Yang, Hailong Yang, Likai Zhou, Nanqiao Zheng, Chenming Hu, Zhanqiang Xu
  • Patent number: 10840638
    Abstract: A connector housing adapted to receive a contact comprises a first latch disposed on a top surface of the housing and having a first pressing part and a first extension portion formed on the first pressing part and a second latch disposed on the top surface of the housing and having a second pressing part and a second extension portion formed on the second pressing part. The first latch and the second latch are disposed side by side on the top surface and are adapted to lock to a case of a mating connector. The first latch and the second latch are unlocked by pressing down the first pressing part and the second pressing part. The first extension portion and the second extension portion are disposed adjacent to each other.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: November 17, 2020
    Assignees: Tyco Electronics (Shanghai) Co. Ltd., TE Connectivity India Private Limited, Tyco Electronics AMP Italia S.r.l.
    Inventors: Dhanesh M K, Hongbo Zhang, Riccardo Francesco Robone
  • Patent number: 10823679
    Abstract: A scanning type laser induced spectrum surface range analysis and detection system includes a laser emitting head connected to an external laser inducing light source, which generates lasers emitted through the laser emitting head, so as to generate laser induced plasma. A focusing optical device converges induction excited laser beams emitted by the laser emitting head onto a surface of a tested sample. Then, a reflector collects wide spectral range induced plasma scattered light signals of the tested sample and converges the signals into a light collecting device. The light collecting device converges induced plasma scattered light into an optical fiber and transmits the induced plasma scattered light to an external spectrograph; and the external spectrograph divides a spectrum formed by the plasma to obtain spectral strength data of different wavelengths.
    Type: Grant
    Filed: November 24, 2016
    Date of Patent: November 3, 2020
    Assignee: Academy of Opto-Electronics Chinese Academy of Sciences
    Inventors: Tianzhuo Zhao, Fuqiang Lian, Zeqiang Mo, Weiran Lin, Yang Liu, Shuzhen Nie, Hong Xiao, Hongbo Zhang, Zhongwei Fan
  • Patent number: 10802718
    Abstract: A method for garbage collection of a volume in a log-structured file system is disclosed. The volume comprises a plurality of segments. Each of the segments comprises a plurality of blocks. An invalid block count of each of the segments is determined. The invalid block count is used as an index for ordering the segments in a garbage collection queue. A plurality of range areas are determined for the index. A migration rate of each range area is determined, and the migration rate of a given range area reflects an intensity of segment migration into/out of the given range area. A negative migration rate reflects a segment migration into the given range area. Garbage collection is performed based upon the migration rate.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: October 13, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Vyacheslav Anatolievich Dubeyko, Hongbo Zhang
  • Publication number: 20200278343
    Abstract: A method of detecting integrated stress response activity in living cells comprising inducing UL148-marker expression, scanning the cells to determine if the UL148 is punctate or diffuse, and ranking the level of ISR activity based on how punctate the UL148 is in the cell. The marker may be a fluorescent marker. The fluorescent marker may be Green fluorescent protein. The cell may be an epithelial cell. The cells may be ARPE-19 epithelial cells carrying a doxycycline inducible gene expression cassette encoding UL148-GFP and treating the cells for 18 hours with 100 ng/mL doxycycline hyclate to induce UL148-GFP expression. The cells may have an inducible gene expression cassette encoding UL148-marker expression. The UL148-marker expression may be induced by the cell being treated with an antibiotic. The method may include adding marker to the cells. The cells may be mutated to express UL148-marker upon inducement. A kit to conduct the method.
    Type: Application
    Filed: February 28, 2020
    Publication date: September 3, 2020
    Inventors: Jeremy P. KAMIL, Nathaniel MOORMAN, Hongbo ZHANG, Christopher NGUYEN
  • Patent number: 10720717
    Abstract: A conductive terminal adapted to be mounted in an insulation housing of a connector includes a mating portion disposed at a front of the conductive terminal and adapted to engage a mating terminal of a mating connector, a crimping portion disposed at a rear of the conductive terminal and adapted to be crimped onto a wire, and a pressing portion disposed at a rear end of the crimping portion and extending outward. The conductive terminal is adapted to be held in the insulation housing by pushing the pressing portion.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: July 21, 2020
    Assignee: Tyco Electronics (Shanghai) Co. Ltd.
    Inventors: Qin Xu, Hongbo Zhang
  • Patent number: 10691015
    Abstract: A method and apparatus of a novel modeling scheme for performing optical lithography simulation for a multi-tone mask with a plurality of mask tones is described. The method generates a transmission function matrix based on a setting of the multi-tone mask. The method applies the transmission function matrix to transform a formula for calculating light intensity from Abbe's form to Hopkins' form while maintaining the accuracy of Abbe's form. The method then computes the light intensity using the transformed formula.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: June 23, 2020
    Inventors: Hongbo Zhang, Qiliang Yan
  • Patent number: 10680375
    Abstract: A connection terminal is provided and includes a body, a welding pin, a first stop, a second stop, and a third stop. The body includes a pair of planar surfaces and a pair of side surfaces. The welding pin extends from an end of the body. The first stop extends outwardly from one of the pair of side surfaces, while the second stop extends outwardly from another of the pair of side surfaces. The third stop protrudes outwardly from one of pair of planar surfaces.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: June 9, 2020
    Assignee: Tyco Electronics (Shanghai) Co. Ltd.
    Inventors: Chaofan Li, Hongbo Zhang, Yongjia Wang
  • Publication number: 20200168389
    Abstract: A transformer and a switch-mode power supply are provided. The transformer includes: a magnetic core structure; several windings that surround a same magnetic cylinder in the magnetic core structure in a stacked manner, where the several windings include at least one primary-side winding and at least one secondary-side winding; and an electromagnetic shielding layer that is disposed between at least two adjacent windings, where the two adjacent windings are a primary-side winding and a secondary-side winding, and the electromagnetic shielding layer is made of a magnetic material. The electromagnetic shielding layer of the transformer can suppress a noise current of the winding, to reduce noise.
    Type: Application
    Filed: May 5, 2017
    Publication date: May 28, 2020
    Inventors: Hongbo Zhang, Yongjun Dai, Xiaosong Liu, Qinghai Wang
  • Patent number: RE48063
    Abstract: A fiber optic cable distribution box has an interface compartment for interfacing a first set of fibers when routed inside the compartment, with a second set of fibers associated with a fiber optic cable that is routed to the box. A drum region is disposed beneath the interface compartment. The drum region includes a cylindrical wall for supporting a fiber optic cable wound about the wall. The drum region is formed so that the box can turn about the axis of the cylindrical wall when a cable is paid out from the drum region. The interface compartment and the drum region are constructed so that the first set of fibers inside the interface compartment, originate from an inside end portion of the cable wound on the drum region.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: June 23, 2020
    Assignee: CommScope Technologies LLC
    Inventors: Daniel Hendrickson, Hongbo Zhang
  • Patent number: D900164
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: October 27, 2020
    Assignee: Nantong Wotell Machinery Manufacturing Co., LTD.
    Inventors: Hongbo Zhang, Feixiong Mao