Abstract: A method for preparing (S)-nicotine by reduction includes conducting a reduction process on an alkene compound as shown in Formula I and/or an iminium cation compound as shown in Formula II, thereby producing (S)-nicotine. The method is simple, safe, reliable, and yields both high purity and high quantities of (S)-nicotine production.

Abstract: A Streptococcus suis (S. suis) vaccine is provided. For the S. suis vaccine, an antigen is a protein with an amino acid sequence shown in SEQ ID NO: 2. A preparation method of the S. suis vaccine is provided, including the following steps: mixing a white oil and aluminum stearate to obtain a white oil adjuvant; adding poly sorbate 80 to an aqueous solution of the protein with the amino acid sequence shown in SEQ ID NO: 2, and thoroughly mixing to obtain an antigen solution; and mixing the antigen solution with the white oil adjuvant according to a volume ratio of (0.5-1.5):2, and emulsifying to obtain the S. suis vaccine. An animal immunized with the S. suis vaccine of the present disclosure can effectively resist the attack of S. suis serotype 2, 3, and 31, with a vaccine protection rate as high as 100%.

Abstract: Disclosed are recombinant adenoviral compositions and methods for their use in treating disorders associated with epithelial tissues.

Abstract: An on-chip adaptive optical receiver system, an optical chip, and a communication device are disclosed, which are applied to optical communication. The on-chip adaptive optical receiver system includes an antenna array configured for separating received spatial light to obtain a plurality of sub-light spots; an optical phased array configured for performing phase-shifting processing and beam combining processing on the sub-light spots to obtain combined light; and an optical receiving module configured for demultiplexing the combined light to obtain beacon light. The optical receiving module is further configured for detecting intensity information of the beacon light and generating a feedback signal according to the intensity information.

Abstract: A power converter includes a primary H-bridge with switches and an LCL-Transformer section with a first inductor with a first end connected to a first terminal of the primary H-bridge, a capacitor connected between a second end of the first inductor and a second terminal of the primary H-bridge, and a second inductor with a first end connected to the second end of the first inductor. The converter includes a transformer with a primary connected between a second end of the second inductor and the second terminal of the primary H-bridge, a secondary H-bridge with switches with an input connected to a secondary side of the transformer, and an output capacitor connected across output terminals of the secondary H-bridge. The primary H-bridge is fed by a DC constant current source and the output terminals of the secondary H-bridge have a regulated DC output voltage are connected to a load.

Abstract: The present invention provides recombinant adenoviral compositions and methods for their use in treating disorders associated with epithelial tissues.

Abstract: The current disclosure provides recombinant adenoviral vectors and adenoviral genomes that can accommodate or that contain a large transposon payload, for instance a transposon payload of up to 40 kb. The adenoviral vectors and genomes can deliver the large transposon payload into a target genome, for instance for gene therapy.

Abstract: A method for a dynamic inductive wireless power transmission includes providing an AC/DC power converter that receives three-phase power and provides regulated DC output current, connecting a trunk cable to the AC/DC power converter output and to multiple power transmitter modules. The trunk cable connects inputs of the power transmitter modules in series. The power transmitter modules transmit inductive wireless power over an air gap. The method includes providing a system controller that detects a vehicle containing a receiver coil and confirms if the vehicle should receive the inductive wireless power from the multiple power transmitter modules, and includes configuring the system controller to communicate with the AC/DC power converter to maintain the regulated DC output current at a constant value and transmit the inductive wireless power to the vehicle through the multiple power transmitter modules when the vehicle should receive the inductive wireless power.

Abstract: A power converter includes an unfolder connected to a three-phase source and has an output connection with three output terminals. A three-input converter connected to the unfolder produces a quasi-sinusoidal output voltage across converter output terminals. Switches of the converter selectively connect each of the three output terminals across the converter output terminals. A pulse-width modulation controller controls a first duty ratio and a second duty ratio for the converter based on a phase angle of the source and a modulation index generated from an error signal related to a control variable. The duty ratios are time varying at a rate related to a fundamental frequency of the source. The modulation index relates to output voltage of the converter, peak voltage or current of the source and/or peak current at the output terminals.

Abstract: An apparatus monitoring system stability of a DC power system includes a switching power converter with a control loop. The converter is connected to a DC bus of the system. A monitoring loop injected into the control loop includes a sensor circuit monitoring voltage and current of the DC bus and a small signal injector producing a periodic signal with variable amplitude and frequency and injects the periodic signal on a reference signal of the control loop. The monitoring loop includes a stability measurement circuit that varies a frequency input to the small signal injector until the periodic signal has a frequency equal to a system minor loop gain crossover frequency of an impedance ratio of a converter closed loop output impedance and an impedance of the DC power system. The monitoring loop includes a measurement output circuit that outputs a DC power system stability margin at the crossover frequency.

Abstract: A power converter includes a primary H-bridge with switches and an LCL-T section with a first inductor with a first end connected to a first terminal of the primary H-bridge, a capacitor connected between a second end of the first inductor and a second terminal of the primary H-bridge, and a second inductor with a first end connected to the second end of the first inductor. The converter includes a transformer with a primary connected between a second end of the second inductor and the second terminal of the primary H-bridge, a secondary H-bridge with switches with an input connected to a secondary side of the transformer, and an output capacitor connected across output terminals of the secondary H-bridge. The primary H-bridge is fed by a DC constant current source and the output terminals of the secondary H-bridge have a regulated DC output voltage are connected to a load.

Abstract: An power converter includes an unfolder connected to a three-phase source and has an output connection with a positive terminal, a negative terminal and a neutral terminal. The unfolder creates two unipolar piece-wise sinusoidal DC voltage waveforms offset by a half of a period. A three-input converter connected to the unfolder produces a quasi-sinusoidal output voltage across output terminals. Switches of the converter selectively connect the positive, negative and neutral inputs across the output terminals. A PWM controller controls a first duty ratio and a second duty ratio for the converter based on a phase angle of the source and a modulation index generated from an error signal related to a control variable. The duty ratios are time varying with a fundamental frequency of the source. The modulation index relates to output voltage of the converter, peak voltage or current of the source and/or peak current at the output terminals.

Abstract: An power converter includes an unfolder connected to a three-phase source and has an output connection with a positive terminal, a negative terminal and a neutral terminal. The unfolder creates two unipolar piece-wise sinusoidal DC voltage waveforms offset by a half of a period. A three-input converter connected to the unfolder produces a quasi-sinusoidal output voltage across output terminals. Switches of the converter selectively connect the positive, negative and neutral inputs across the output terminals. A PWM controller controls a first duty ratio and a second duty ratio for the converter based on a phase angle of the source and a modulation index generated from an error signal related to a control variable. The duty ratios are time varying with a fundamental frequency of the source. The modulation index relates to output voltage of the converter, peak voltage or current of the source and/or peak current at the output terminals.

Abstract: A power converter includes an unfolder connected to a three-phase source and has an output connection with three output terminals. A three-input converter connected to the unfolder produces a quasi-sinusoidal output voltage across converter output terminals. Switches of the converter selectively connect each of the three output terminals across the converter output terminals. A pulse-width modulation controller controls a first duty ratio and a second duty ratio for the converter based on a phase angle of the source and a modulation index generated from an error signal related to a control variable. The duty ratios are time varying at a rate related to a fundamental frequency of the source. The modulation index relates to output voltage of the converter, peak voltage or current of the source and/or peak current at the output terminals.

Abstract: A package structure includes: a substrate; a chip arranged on a part of a surface of the substrate; a metal thermal conducting layer arranged on a top surface of the chip; a capacitive structure arranged on another part of the surface of the substrate and arranged to be independent from the chip; and a cover including a first cover layer and a second cover layer connected to the first cover layer. A first opening is defined to extend through the first and the second cover layers. The second cover layer is arranged on a bottom of the first cover layer and perpendicular to the first cover layer. The first cover layer is arranged on the capacitive structure. The chip is received in the first opening. The second cover layer is arranged between the capacitive structure and the chip, and is fixed to the substrate.

Abstract: The present disclosure provides, among other things, helper-dependent adenoviral serotype 35 (Ad35) vectors. In various embodiments, helper-dependent Ad35 vectors can be used to deliver a therapeutic payload to a subject in need thereof. Exemplary payloads can encode replacement proteins, antibodies, CARs, TCRs, small RNAs, and genome editing systems. In certain embodiments, a helper-dependent Ad35 vector is engineered for integration of a payload into a host cell genome. The present disclosure further includes methods of gene therapy that include administration of a helper-dependent Ad35 vector to a subject in need thereof.

Abstract: The present invention provides recombinant adenoviral compositions and methods for their use in treating disorders associated with epithelial tissues.

Abstract: The present invention provides recombinant adenoviral compositions and methods for their use in treating disorders associated with epithelial tissues.

Abstract: An apparatus monitoring system stability of a DC power system includes a switching power converter with a control loop. The converter is connected to a DC bus of the system. A monitoring loop injected into the control loop includes a sensor circuit monitoring voltage and current of the DC bus and a small signal injector producing a periodic signal with variable amplitude and frequency and injects the periodic signal on a reference signal of the control loop. The monitoring loop includes a stability measurement circuit that varies a frequency input to the small signal injector until the periodic signal has a frequency equal to a system minor loop gain crossover frequency of an impedance ratio of a converter closed loop output impedance and an impedance of the DC power system. The monitoring loop includes a measurement output circuit that outputs a DC power system stability margin at the crossover frequency.