Patents by Inventor Hongjie Zhang

Hongjie Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9211333
    Abstract: The present invention is in the field of pharmaceuticals and chemical industries. In particular, the present invention relates to new anticancer agents based on miliusane compounds. The present invention also includes its preparation and application method for treating cancer.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 15, 2015
    Assignee: HONG KONG BAPTIST UNIVERSITY
    Inventor: Hongjie Zhang
  • Patent number: 9185761
    Abstract: An Alternate Current (AC) white Light-Emitting Diode (LED) device is provided, which belongs to the technical field of white LED manufacturing. The problem to be solved by the present invention is to low-costly overcome a series of deficiencies such as the stroboflash of an AC driven LED, and the heat dissipation difficulty caused by an integrated packaging of multiple LEDs. A white LED unit includes an LED chip and a light emitting material that can emit light when being excited by the LED chip. The luminous lifetime of the light emitting material is 1-100 ms. The LED chip only comprises one PN junction. The light emitted by the LED chip is mixed with the light emitted by the light emitting material to form white light. The white LED unit is driven by AC with a frequency not more than 100 Hz. The white LED device of prevent invention uses the single PN junction chip, rather than the prior integrated packaged AC multi-LED chip.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: November 10, 2015
    Assignees: Sichuan Sunfor Light Co., Ltd., Changchun Institute of Applied Chemistry, Chinese Academy of Science
    Inventors: Hongjie Zhang, Ming Zhang, Chengyu Li, Kun Zhao, Dongming Li, Li Zhang
  • Publication number: 20150232754
    Abstract: The invention relates to a yellow light afterglow material and a preparation method thereof as well as an LED illuminating device using the same. The yellow light afterglow material comprises the chemical formula of aY2O3.bAl2O3.cSiO2:mCe.nB.xNa.yP, where a, b, c, m, n, x and y are coefficients, and a is not less than 1 but not more than 2, b is not less than 2 but not more than 3, c is not less than 0.001 but not more than 1, m is not less than 0.0001 but not more than 0.6, n is not less than 0.0001 but not more than 0.5, x is not less than 0.0001 but not more than 0.2, and y is not less than 0.0001 but not more than 0.5; wherein Y, Al and Si are substrate elements, and Ce, B, Na and P are activators. The yellow light afterglow material is prepared by the following steps: weighing oxides of elements or materials which can generate oxides at high temperature by molar ratio as raw materials, evenly mixing and then sintering the raw materials at 1200-1700° in a reducing atmosphere.
    Type: Application
    Filed: April 30, 2015
    Publication date: August 20, 2015
    Inventors: Hongjie ZHANG, Ming ZHANG, Chengyu LI, Kun ZHAO, Hao ZHANG
  • Publication number: 20150232753
    Abstract: The invention relates to a yellow light afterglow material and a preparation method thereof as well as an LED illuminating device using the same. The yellow light afterglow material comprises the chemical formula of aY2O3.bAl2O3.cSiO2:mCe.nB.xNa.yP, where a, b, c, m, n, x and y are coefficients, and a is not less than 1 but not more than 2, b is not less than 2 but not more than 3, c is not less than 0.001 but not more than 1, m is not less than 0.0001 but not more than 0.6, n is not less than 0.0001 but not more than 0.5, x is not less than 0.0001 but not more than 0.2, and y is not less than 0.0001 but not more than 0.5; wherein Y, Al and Si are substrate elements, and Ce, B, Na and P are activators. The yellow light afterglow material is prepared by the following steps: weighing oxides of elements or materials which can generate oxides at high temperature by molar ratio as raw materials, evenly mixing and then sintering the raw materials at 1200-1700° in a reducing atmosphere.
    Type: Application
    Filed: April 30, 2015
    Publication date: August 20, 2015
    Inventors: Hongjie ZHANG, Ming ZHANG, Chengyu LI, Kun ZHAO, Hao ZHANG
  • Patent number: 9045689
    Abstract: The invention relates to a yellow light afterglow material and a preparation method thereof as well as an LED illuminating device using the same. The yellow light afterglow material comprises the chemical formula of aY2O3.bAl2O3.cSiO2:mCe.nB.xNa.yP, where a, b, c, m, n, x and y are coefficients, and a is not less than 1 but not more than 2, b is not less than 2 but not more than 3, c is not less than 0.001 but not more than 1, m is not less than 0.0001 but not more than 0.6, n is not less than 0.0001 but not more than 0.5, x is not less than 0.0001 but not more than 0.2, and y is not less than 0.0001 but not more than 0.5; wherein Y, Al and Si are substrate elements, and Ce, B, Na and P are activators. The yellow light afterglow material is prepared by the following steps: weighing oxides of elements or materials which can generate oxides at high temperature by molar ratio as raw materials, evenly mixing and then sintering the raw materials at 1200-1700° in a reducing atmosphere.
    Type: Grant
    Filed: November 9, 2009
    Date of Patent: June 2, 2015
    Assignees: SICHUAN SUNFOR LIGHT CO., LTD., CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES
    Inventors: Hongjie Zhang, Ming Zhang, Chengyu Li, Kun Zhao, Hao Zhang
  • Publication number: 20150139725
    Abstract: An apparatus comprising: a support comprising a planar support surface; first protrusions protruding from the planar support surface and located on the planar support surface to position a first planar component within a first area; and second protrusions protruding from the planar support surface and located on the planar support surface to position a second planar component within a second area, which overlaps the first area, wherein at least some of the second protrusions are located within the first area and are configured to retract from a first protruding configuration for positioning a second planar component into a second retracted configuration for enabling the first protrusions to position a first planar component.
    Type: Application
    Filed: May 15, 2012
    Publication date: May 21, 2015
    Inventors: Chong Chen, Hongji Zhang
  • Publication number: 20150122943
    Abstract: An integrated pylon structure for a propulsion system is suitable for one end to be connected to an aircraft wing and the other end to be connected to an aircraft engine. The pylon structure includes a pylon box section (110) formed from an upper and a lower bean, a frame (100) and a side wall panel. The pylon structure has a thrust reverser hood connection structure, provided on the side wall and connected with a nacelle thrust reverser hood having a front fixed hood (301) and a rear movable hood (302). A guide rail allows the rear movable hood to slide and open relative to the pylon box section. The engine thrust reverser hood is directly connected to the side wall of the pylon box section and a guide rail on the side wall guides the opening of the thrust reverser hood.
    Type: Application
    Filed: December 12, 2013
    Publication date: May 7, 2015
    Inventors: Guanghui Wu, Kecen Han, Liangdao Zhou, Qifeng Yu, Guozheng Lin, Hongjie Zhang, Shibiao Zhang, Haojie Weng, Haisha Guo, Pengfei Zhang, Xiaonan Li, Shiwei Ma, Yinyin Hu, Sen Peng, Honggang Tang, Mingpeng Yan
  • Publication number: 20140357584
    Abstract: Provided herein are glycosidic aryl naphthalide lignans compounds, such as justiprocumin A isolated from the plant Justicia gendarussa Burm f. (Acanthaceae), which are effective in the treatment of AIDS and HIV infections.
    Type: Application
    Filed: July 27, 2012
    Publication date: December 4, 2014
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Hongjie Zhang, Djaja Soejarto, Lijun Rong, Harry H.S. Fong, Emily Rumschlag-Booms
  • Publication number: 20140348965
    Abstract: A method for suppressing activation of pancreatic stellate cells of a subject includes administering a composition comprising a therapeutically effective amount of Eruberin A. A method of preventing, alleviating or treating pancreatic tumors or pancreatic tumors related diseases includes administering a composition comprising a therapeutically effective amount of Eruberin A. The Eruberin A may be extracted from Pronephrium penangianum.
    Type: Application
    Filed: May 22, 2013
    Publication date: November 27, 2014
    Applicant: Hong Kong Baptist University
    Inventors: Zhaoxiang Bian, Siu Wai Tsang, Hongjie Zhang, Yegao Chen, Aiping Lu, Albert Sun-Chi Chan, Hongxi Xu, Shilin Chen, Dajian Yang
  • Publication number: 20140107018
    Abstract: A compound having formula (I) or formula (II): for use in anticancer or anti-obesity.
    Type: Application
    Filed: March 14, 2013
    Publication date: April 17, 2014
    Inventor: Hongjie Zhang
  • Patent number: 8691825
    Abstract: The instant invention provides for substituted fused pyrimidine compounds of Formula A that inhibit Akt activity: In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: April 8, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Qi Chen, Mingxiang Cui, Bin Hu, Shuangxi Hu, Zhifa Pu, Philip E. Sanderson, Richard Soll, Xue Tang, Jiabing Wang, Yongjin Yan, Jinfeng Yao, Hongjie Zhang
  • Publication number: 20130324580
    Abstract: The present invention is in the field of pharmaceuticals and chemical industries. In particular, the present invention relates to new anticancer agents based on miliusane compounds. The present invention also includes its preparation and application method for treating cancer.
    Type: Application
    Filed: March 15, 2013
    Publication date: December 5, 2013
    Applicant: HONG KONG BAPTIST UNIVERSITY
    Inventor: Hongjie ZHANG
  • Publication number: 20130221870
    Abstract: An Alternate Current (AC) white Light-Emitting Diode (LED) device is provided, which belongs to the technical field of white LED manufacturing. The problem to be solved by the present invention is to low-costly overcome a series of deficiencies such as the stroboflash of an AC driven LED, and the heat dissipation difficulty caused by an integrated packaging of multiple LEDs. A white LED unit includes an LED chip and a light emitting material that can emit light when being excited by the LED chip. The luminous lifetime of the light emitting material is 1-100 ms. The LED chip only comprises one PN junction. The light emitted by the LED chip is mixed with the light emitted by the light emitting material to form white light. The white LED unit is driven by AC with a frequency not more than 100 Hz. The white LED device of prevent invention uses the single PN junction chip, rather than the prior integrated packaged AC multi-LED chip.
    Type: Application
    Filed: March 1, 2011
    Publication date: August 29, 2013
    Applicants: CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES, SICHUAN SUNFOR LIGHT CO., LTD.
    Inventors: Hongjie Zhang, Ming Zhang, Chengyu Li, Kun Zhao, Dongming Li, Li Zhang
  • Publication number: 20120181566
    Abstract: The invention relates to a yellow light afterglow material and a preparation method thereof as well as an LED illuminating device using the same. The yellow light afterglow material comprises the chemical formula of aY2O3.bAl2O3.cSiO2:mCe.nB.xNa.yP, where a, b, c, m, n, x and y are coefficients, and a is not less than 1 but not more than 2, b is not less than 2 but not more than 3, c is not less than 0.001 but not more than 1, m is not less than 0.0001 but not more than 0.6, n is not less than 0.0001 but not more than 0.5, x is not less than 0.0001 but not more than 0.2, and y is not less than 0.0001 but not more than 0.5; wherein Y, Al and Si are substrate elements, and Ce, B, Na and P are activators. The yellow light afterglow material is prepared by the following steps: weighing oxides of elements or materials which can generate oxides at high temperature by molar ratio as raw materials, evenly mixing and then sintering the raw materials at 1200-1700° in a reducing atmosphere.
    Type: Application
    Filed: November 9, 2009
    Publication date: July 19, 2012
    Applicants: CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES, SICHUAN SUNFOR LIGHT CO., LTD.
    Inventors: Hongjie Zhang, Ming Zhang, Chengyu Li, Kun Zhao, Hao Zhang
  • Publication number: 20120077810
    Abstract: The instant invention provides for substituted fused pyrimidine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
    Type: Application
    Filed: March 29, 2010
    Publication date: March 29, 2012
    Inventors: Qi Chen, Mingxiang Cui, Bin Hu, Shuangxi Hu, Zhifa Pu, Philip E. Sanderson, Richard Soll, Xue Tang, Jiabing Wang, Yongjin Yan, Jinfeng Yao, Hongjie Zhang
  • Publication number: 20100173288
    Abstract: This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject.
    Type: Application
    Filed: December 6, 2007
    Publication date: July 8, 2010
    Inventors: Chenyu Zhang, Junfeng Zhang, Xi Chen, Yi Ba, Jiangning Chen, Jin Wang, Ke Zeng, Hongjie Zhang
  • Patent number: 7744814
    Abstract: Methods for producing a magnesium-rare earth intermediate alloy, which belongs to the technical field of molten salt electrolytic metallurgical technology. In one embodiment, the method comprises subjecting magnesium chloride, lanthanum praseodymium cerium chloride and potassium chloride to an electrolysis, and adding additional lanthanum praseodymium cerium chloride and magnesium chloride during the electrolysis. In the electrolysis process, neither metal magnesium nor rare earth metal is used, only the chlorides of rare earths and magnesium are used and the rare earth ions and the magnesium ions are co-electrodeposited on the cathode, so as to obtain the intermediate alloy having a melting point close to the eutectic temperature of the rare earth and magnesium. The method has various advantages including but not limited to high operability, simple process and equipment, stable quality of product by mass production and easy for commercial scale production.
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: June 29, 2010
    Assignee: Changchun Institute of Applied Chemistry Chinese Academy of Sciences
    Inventors: Jian Meng, Daqing Fang, Deping Zhang, Jiacheng Shen, Dingxiang Tang, Hongjie Zhang
  • Patent number: 7708937
    Abstract: A high-strength, high-toughness, weldable and deformable rare earth magnesium alloy comprised of 0.7˜1.7% of Ym, 5.5˜6.4% of Zn, 0.45˜0.8% of Zr, 0.02% or less of the total amount of impurity elements of Si, Fe, Cu and Ni, and the remainder of Mg, based on the total weight of the alloy. During smelting, Y, Ho, Er, Gd and Zr are added in a manner of Mg—Y-rich, Mg—Zr intermediate alloys into a magnesium melt; Zn is added in a manner of pure Zn, and at 690˜720° C., a round bar was cast by a semi-continuous casting or a water cooled mould, then an extrusion molding was performed at 380˜410° C. after cutting. Before the extrusion, the alloy is treated by the solid-solution treatment at 480˜510° C. for 2˜3 hours, however, the alloy can also be extrusion molded directly without the solid-solution treatment.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: May 4, 2010
    Assignee: Changchun Institute of Applied Chemistry Chinese Academy of Sciences
    Inventors: Jian Meng, Daqing Fang, Deping Zhang, Dingxiang Tang, Huayi Lu, Lianshan Zhao, Wei Sun, Xin Qiu, Hongjie Zhang
  • Publication number: 20090263271
    Abstract: A high-strength, high-toughness, weldable and deformable rare earth magnesium alloy comprised of 0.7˜1.7% of Ym, 5.5˜6.4% of Zn, 0.45˜0.8% of Zr, 0.02% or less of the total amount of impurity elements of Si, Fe, Cu and Ni, and the remainder of Mg, based on the total weight of the alloy. During smelting, Y, Ho, Er, Gd and Zr are added in a manner of Mg—Y-rich, Mg—Zr intermediate alloys into a magnesium melt; Zn is added in a manner of pure Zn, and at 690˜720° C., a round bar was cast by a semi-continuous casting or a water cooled mould, then an extrusion molding was performed at 380˜410° C. after cutting. Before the extrusion, the alloy is treated by the solid-solution treatment at 480˜510° C. for 2˜3 hours, however, the alloy can also be extrusion molded directly without the solid-solution treatment.
    Type: Application
    Filed: April 17, 2008
    Publication date: October 22, 2009
    Applicant: CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES
    Inventors: Jian Meng, Daqing Fang, Deping Zhang, Dingxiang Tang, Huayi Lu, Lianshan Zhao, Wei Sun, Xin Qiu, Hongjie Zhang
  • Publication number: 20090166216
    Abstract: The invention relates to a method for producing a magnesium-rare earth intermediate alloy, which belongs to the technical field of molten salt electrolytic metallurgical technology. Inside an electrolysis oven, magnesium chloride, lanthanum praseodymium cerium chloride and potassium chloride in a controlled mass ratio of 5:(40-35):(55-60) are formulated as electrolyte composition, and the electrolysis is performed under a temperature of 800-900° C., a cathode current density of 10-30 A/cm2, and a distance between the electrodes of 4 to 8 cm; and the lanthanum praseodymium cerium chloride and the magnesium chloride are added in a mass ratio of 1:1.5-5 during the electrolysis, thus the magnesium-lanthanum praseodymium cerium intermediate alloy is produced.
    Type: Application
    Filed: December 23, 2008
    Publication date: July 2, 2009
    Applicant: CHANGCHUNG INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES
    Inventors: Jian MENG, Daqing FANG, Deping ZHANG, Jiacheng SHEN, Dingxiang TANG, Hongjie ZHANG