Patents by Inventor Hongliang Chen

Hongliang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250205208
    Abstract: Use of a C-JUN N-terminal kinase inhibitor, SU3327, in the preparation of a medicament for reducing cytotoxicity and nephrotoxicity of polymyxin, wherein the polymyxin is preferably Polymyxin E. A treatment with a combination of SU3327 and Polymyxin E can significantly inhibit cytotoxicity and nephrotoxicity of Polymyxin E.
    Type: Application
    Filed: January 22, 2024
    Publication date: June 26, 2025
    Applicants: XIAMEN HANLIXIN PHARMACEUTICAL CO., LTD., CHINA AGRICULTURAL UNIVERSITY
    Inventors: Chongshan DAI, Hongliang CHEN, Congming WU, Hailing ZHENG, Jianzhong SHEN
  • Publication number: 20250170106
    Abstract: The present invention provides use of a C-JUN N-terminal kinase inhibitor, SU3327, in the preparation of a medicament for enhancing the efficacy of polymyxin against bacterial infection, and use of a composition of SU3327 and polymyxin in the preparation of a medicament for an enhanced efficacy against bacterial infection, wherein the polymyxin is preferably Polymyxin E. The invention not only shows an enhanced antibacterial activity of polymyxin by SU3327 in synergy through minimum inhibitory concentration tests in checkerboard assays and in vitro bacterial growth curves, but also confirms the ability of SU3327 to enhance polymyxin along with its effectiveness in vivo in the experiments with a model of mice infected with drug resistant bacteria at the animal level. The invention provides a new use of SU3327 in enhancing antibacterial activities of polymyxin antibiotics, resolving the technical problems such as clinical resistance to polymyxin, low clinical therapeutic index of polymyxin, etc.
    Type: Application
    Filed: September 19, 2023
    Publication date: May 29, 2025
    Applicants: XIAMEN HANLIXIN PHARMACEUTICAL CO., LTD., CHINA AGRICULTURAL UNIVERSITY
    Inventors: Jianzhong SHEN, Chongshan DAI, Hongliang CHEN, Congming WU, Zhangqi SHEN, Yang WANG
  • Patent number: 12077630
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one acetoacetate ester or amide and at least one aminoalcohol or alkylhydroxylamine. Foams so produced emit low levels of formaldehyde, acetaldehyde and propionaldehyde.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: September 3, 2024
    Assignee: Dow Global Technologies LLC
    Inventors: Zhengming Tang, Hongliang Chen, Jian Zou, Shaoguang Feng, Steven Zhang, Degang Zhang, Ping Zhang
  • Patent number: 11923690
    Abstract: A wireless charging apparatus for a wireless power transmission system and a method are provided. The apparatus includes a voltage conversion circuit, an excitation coil, n first resonance coils, and a controller, where n is greater than or equal to 3. The voltage conversion circuit is connected to the excitation coil and converts a power grid voltage into a high-frequency alternating current voltage. The excitation coil generates a magnetic field based on the high-frequency alternating current voltage. The n first resonance coils are arranged in different directions and conducts the magnetic field, and the controller monitors power statuses of the first resonance coils, and enable or disable the first resonance coils based on the power statuses.
    Type: Grant
    Filed: November 18, 2020
    Date of Patent: March 5, 2024
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Hongliang Chen, Wei Chen, Changsheng Pei, Yongfa Zhu
  • Patent number: 11820855
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one cyclic 1,3-diketone and at least one aminoalcohol or alkylhydroxylamine. Foams so produced emit low levels of formaldehyde, acetaldehyde and propionaldehyde.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: November 21, 2023
    Inventors: Hongliang Chen, Zhengming Tang, Jian Zou, Shaoguang Feng, Degang Zhang, Ping Zhang
  • Patent number: 11603428
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, a polyethyleneamine mixture having a number average molecular weight of 175 to 450 and an alkali metal, phosphonium or ammonium sulfite. Foams so produced emit low levels of formaldehyde, acetaldehyde, acrolein and propionaldehyde.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: March 14, 2023
    Assignee: Dow Global Technologies LLC
    Inventors: Zhengming Tang, Jian Zou, Shaoguang Feng, Yuji Sasaki, Hongliang Chen, Haiying Li, Degang Zhang, Ping Zhang
  • Patent number: 11545640
    Abstract: Disclosed are a series of photoisomeric compounds, preparation method therefor and device comprising the compounds, wherein a photoisomeric compound-graphene molecular junction device is formed by linking the photoisomeric compound to a gap of two-dimensional monolayer graphene having a nano-gap array via an amide covalent bond. When a single photoisomeric compound is bridged to the gap of the two-dimensional monolayer graphene having a nano-gap array, the devices have a reversible light-controlled switching function and a reversible electrically-controlled switching function. A molecular switch device prepared by the method can achieve a high reversibility and a good reproducibility. The number of light-controlled switching cycles can exceed 104, and the number of electrically-controlled switching cycles can reach about 105 or greater. Moreover, the above-mentioned reversible molecular switch device remains stable within a period of more than one year.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: January 3, 2023
    Assignee: PEKING UNIVERSITY
    Inventors: Xuefeng Guo, Chuancheng Jia, Na Xin, Hongliang Chen, Mingliang Li, Dahui Qu
  • Patent number: 11479650
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one cyclic 1,3-diketone compound, at least one aminoalcohol or alkylhydroxylamine and an alkali metal, phosphonium or ammonium sulfite. Foams so produced emit low levels of formaldehyde, acetaldehyde, acrolein and propionaldehyde.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: October 25, 2022
    Assignee: Dow Global Technologies LLC
    Inventors: Zhengming Tang, Jian Zou, Shaoguang Feng, Yuji Sasaki, Hongliang Chen, Degang Zhang, Ping Zhang
  • Patent number: 11453742
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant, at least one catalyst, and certain aldehyde-suppressing additives. Foams so produced emit low levels of formaldehyde, acetaldehyde and propionaldehyde.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: September 27, 2022
    Assignee: Dow Global Technologies LLC
    Inventors: Zhengming Tang, Hongliang Chen, Jian Zou, Shaoguang Feng, Degang Zhang, Ping Zhang
  • Publication number: 20210309789
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant, at least one catalyst, and certain aldehyde-suppressing additives. Foams so produced emit low levels of formaldehyde, acetaldehyde and propionaldehyde.
    Type: Application
    Filed: August 2, 2018
    Publication date: October 7, 2021
    Inventors: Zhengming Tang, Hongliang Chen, Jian Zou, Shaoguang Feng, Degang Zhang, Ping Zhang
  • Publication number: 20210301065
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, a polyethyleneamine mixture having a number average molecular weight of 175 to 450 and an alkali metal, phosphonium or ammonium sulfite. Foams so produced emit low levels of formaldehyde, acetaldehyde, acrolein and propionaldehyde.
    Type: Application
    Filed: August 2, 2018
    Publication date: September 30, 2021
    Inventors: Zhengming Tang, Jian Zou, Shaoguang Feng, Yuji Sasaki, Hongliang Chen, Haiying Li, Degang Zhang, Ping Zhang
  • Publication number: 20210292508
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one cyclic 1,3-diketone compound, at least one aminoalcohol or alkylhydroxylamine and an alkali metal, phosphonium or ammonium sulfite. Foams so produced emit low levels of formaldehyde, acetaldehyde, acrolein and propionaldehyde.
    Type: Application
    Filed: August 2, 2018
    Publication date: September 23, 2021
    Inventors: Zhengming Tang, Jian Zou, Shaoguang Feng, Yuji Sasaki, Hongliang Chen, Degang Zhang, Ping Zhang
  • Publication number: 20210234109
    Abstract: Disclosed are a series of photoisomeric compounds, preparation method therefor and device comprising the compounds, wherein a photoisomeric compound-graphene molecular junction device is formed by linking the photoisomeric compound to a gap of two-dimensional monolayer graphene having a nano-gap array via an amide covalent bond. When a single photoisomeric compound is bridged to the gap of the two-dimensional monolayer graphene having a nano-gap array, the devices have a reversible light-controlled switching function and a reversible electrically-controlled switching function. A molecular switch device prepared by the method can achieve a high reversibility and a good reproducibility. The number of light-controlled switching cycles can exceed 104, and the number of electrically-controlled switching cycles can reach about 105 or greater. Moreover, the above-mentioned reversible molecular switch device remains stable within a period of more than one year.
    Type: Application
    Filed: January 27, 2021
    Publication date: July 29, 2021
    Inventors: Xuefeng GUO, Chuancheng JIA, Na XIN, Hongliang CHEN, Mingliang LI, Dahui QU
  • Publication number: 20210189054
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one cyclic 1,3-diketone and at least one aminoalcohol or alkylhydroxylamine. Foams so produced emit low levels of formaldehyde, acetaldehyde and propionaldehyde.
    Type: Application
    Filed: August 2, 2018
    Publication date: June 24, 2021
    Inventors: Hongliang Chen, Zhengming Tang, Jian Zou, Shaoguang Feng, Degang Zhang, Ping Zhang
  • Publication number: 20210163670
    Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one acetoacetate ester or amide and at least one aminoalcohol or alkylhydroxylamine. Foams so produced emit low levels of formaldehyde, acetaldehyde and propionaldehyde.
    Type: Application
    Filed: August 2, 2018
    Publication date: June 3, 2021
    Inventors: Zhengming TANG, Hongliang Chen, Jian Zou, Shaoguang Feng, Steven Zhang, Degang Zhang, Ping Zhang
  • Publication number: 20210075261
    Abstract: A wireless charging apparatus for a wireless power transmission system. The apparatus includes a voltage conversion circuit, an excitation coil, n first resonance coils, and a controller, where n is greater than or equal to 3. The voltage conversion circuit is connected to the excitation coil and converts a power grid voltage into a high-frequency alternating current voltage. The excitation coil generates a magnetic field based on the high-frequency alternating current voltage. The n first resonance coils are arranged in different directions and conducts the magnetic field, and the controller monitors power statuses of the first resonance coils, and enable or disable the first resonance coils based on the power statuses.
    Type: Application
    Filed: November 18, 2020
    Publication date: March 11, 2021
    Inventors: Hongliang CHEN, Wei CHEN, Changsheng PEI, Yongfa ZHU
  • Publication number: 20200212328
    Abstract: Disclosed are a series of photoisomeric compounds, preparation method therefor and device comprising the compounds. A photoisomeric compound-grephene molecular junction device is formed by linking the photoisomeric compound to a gap of two-dimensional monolayer graphene having a nano-gap array via an amide covalent bond. When a single photoisomeric compound is bridged to the gap of the two-dimensional monolayer graphene having a nano-gap array, the devices have a reversible light-controlled switching function and a reversible electrically-controlled switching function. A molecular switch device prepared by the method can achieve high reversibility and good reproducibility. The number of light-controlled switching cycles can exceed 104, and the number of electrically-controlled switching cycles can reach about 105 or greater. The reversible molecular switch device remains stable within a period of more than one year.
    Type: Application
    Filed: May 24, 2017
    Publication date: July 2, 2020
    Inventors: Xuefeng GUO, Chuancheng JIA, Na XIN, Hongliang CHEN, Mingliang LI, Dahui QU
  • Publication number: 20190258609
    Abstract: A method for avoiding file deadlock during concurrent access of a sqlite database is disclosed, wherein, in a software design stage, divide the client sqlite database from one into two or more, and each sqlite database is corresponding to the requirement of a certain type of writing operation of the software system. Respectively classify all the data tables used in the software according to the different types of writing operation and place them in different sqlite database files. This could ensure that different types of writing operations are respectively corresponding to different files, and when multiple threads of the application software generate writing operations at the same time, since they respectively write into different physical disk files, so as to avoid the problem that one sqlite database file cannot be concurrently written by multiple threads at the same time.
    Type: Application
    Filed: May 7, 2019
    Publication date: August 22, 2019
    Inventors: Jinyuan Zou, Hongliang Chen
  • Patent number: D849601
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: May 28, 2019
    Assignee: Zhejiang Doohan Technology Co., Ltd.
    Inventors: Guande Li, Hongliang Chen
  • Patent number: D866674
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: November 12, 2019
    Assignee: Guangzhou Ekai Electronic Technology Co., Ltd.
    Inventors: Guande Li, Hongliang Chen