Abstract: A cardiac functional analysis system reconstructs a 3D anatomical image volume using image frames acquired at predetermined cardiac phases over multiple cardiac cycles in response to a trigger derived from hemodynamic signals. A medical imaging system generates 3D anatomical imaging volume datasets from acquired 2D anatomical images. The system includes an image acquisition device for acquiring 2D anatomical images of a portion of patient anatomy in selectable angularly variable imaging planes in response to a synchronization signal derived from a patient blood flow related parameter. A synchronization processor provides the synchronization signal derived from the patient blood flow related parameter. An image processor processes 2D images acquired by the image acquisition device of the portion of patient anatomy in multiple different imaging planes having relative angular separation, to provide a 3D image reconstruction of the portion of patient anatomy.

Abstract: A system improves characterization and diagnosis of cardiac electrophysiological activities by analyzing and characterizing cardiac function signals (including surface ECG signals and intra-cardiac electrograms) based on cardiac electrophysiological energy mode and pattern identification and mapping. The system accurately determines a time stamp, location and severity of cardiac pathology and clinical events by calculating a cardiac signal energy mode and energy variation and distribution. The system identifies cardiac disorders, differentiates cardiac arrhythmias, characterizes pathological severity, predicts life-threatening events, and supports evaluation of administration of drugs.

Abstract: A system for heart performance monitoring stores image data representing a sequence of medical images of a surface of a patient heart acquired over multiple contraction and reperfusion cycles. An image data processor automatically processes the image data to determine, change in displacement of selected points of a region of interest of the heart surface over individual cycles of the multiple contraction and reperfusion cycles, maximum and minimum peak displacement points and associated relative times of occurrence of the maximum and minimum peak displacement points and individual parameters related to change in displacement of corresponding individual points of the selected points. A display image shows a grid of individual parameters and an individual grid cell employs a visual attribute to visually indicate degree of change in an associated individual parameter occurring over the multiple contraction and reperfusion cycles.

Abstract: A system for heart performance characterization and abnormality detection comprises an input processor and a signal processor. The input processor receives first sampled data representing a first signal portion of a heart activity related signal and second sampled data representing a second signal portion of a heart activity related signal. The signal processor determines distribution data associated with degree of similarity between the first and second signal portions by determining a difference between (a) values derived by applying a first function to mean adjusted sampled values of the first signal portion and (b) values derived by applying a second function to mean adjusted sampled values of the second signal portion. In response to the determined distribution data, the signal processor initiates generation of a message associated with the degree of similarity between the first and second signal portions.

Abstract: A system determines fractal values, a nonlinear fractal ratio and fractal data patterns in a heart and maps determined fractal values to medical conditions. A system for heart performance characterization and abnormality detection includes an interface for receiving sampled data representing an electrical signal indicating electrical activity of a patient heart over at least one heart beat cycle. A signal processor calculates, a first signal characteristic value comprising a first fractal dimension value derived from the sampled data over at least a portion of a heart beat cycle, a second signal characteristic value representing a computed derivative of the first fractal dimension value and a ratio of the first and second signal characteristic values. A comparator compares the calculated ratio with a threshold value to provide a comparison indicator.

Abstract: A system provides cardiac arrhythmia detection and performs blood pressure analysis of multiple catheter channels of blood pressure signals to characterize heart hemodynamic activity. A system for heart performance characterization and abnormality detection includes a repository, data processor and output processor. The repository of data comprises, first distribution data representing a probability distribution of a first patient parameter over a first time period and acquired on a first occasion and second distribution data representing a probability distribution of the first patient parameter over a second time period and acquired on a second occasion subsequent to the first occasion. The data processor calculates an overlap indicator indicating degree of overlap of the first distribution data and the second distribution data in a predetermined interval of the distributions. The output processor provides the calculated overlap indicator to a destination device.

Abstract: A patient medical signal processing system adaptively reconstructs a medical signal sampled using a varying sampling rate. The system includes an input processor and a signal processor. The input processor receives first data and second data. The first data represents a first portion of a medical signal derived by sampling at a first sampling rate and the second data represents a second portion of the medical signal derived by sampling at a second sampling rate. The first and the second sampling rates are different and comprise a master clock rate or an integer division of the master clock rate. A signal processor provides a reconstructed sampled medical signal by, interpolating the second data to provide third data at the first sampling rate and combining the first data and the third data to provide the reconstructed sampled medical signal.

Abstract: A system for heart performance characterization and abnormality detection includes an interface for receiving sampled data representing an electrical signal indicating electrical activity of a patient heart over multiple heart beat cycles. A signal processor automatically, decomposes the received sampled data to multiple different subcomponent signals in the time domain. The signal processor associates individual decomposed subcomponents with corresponding different cardiac rotors and determined characteristics of the subcomponents indicating relative significance of the rotors in a cardiac atrial condition. A reproduction device provides data indicating the subcomponent characteristics indicating relative significance of the rotors in a cardiac atrial condition.

Abstract: A system employs non-uniform and nonlinear patient monitoring signals in automatically adaptively varying image resolution, image scanning frequency and acquisition speed and gates and synchronizes the image scanning and acquisition of an imaging system. A system acquires medical images of patient anatomy using a trigger generator. The trigger generator generates a trigger signal comprising a non-periodic sequence of pulses in a first signal portion within individual heart beat cycles. The first signal portion is periodically repeated for multiple sequential individual heart beat cycles. An image acquisition device acquires multiple images of a patient anatomical portion in response to corresponding multiple individual pulses of the non-periodic sequence of pulses. A display processor presents acquired images on a display for review by a user.

Abstract: A device interface selectively acquires patient physiological parameter data. An acquisition processor acquires physiological data from a patient. A communication processor is coupled to an optical communication pathway for receiving a plurality of optical signals from a source. A conversion processor is electrically coupled to the acquisition processor and communication processor and converts a first optical power signal at a first frequency and received via the optical communication pathway using the communication processor, to a first electrical signal for providing power to said device interface. The conversion processor converts an optical control signal at a second frequency different from the first frequency and received via the optical communication pathway using the communication processor, to a second electrical signal for providing control data to the acquisition processor directing the acquisition processor to acquire at least one physiological parameter from a patient.

Abstract: A system for heart performance characterization and abnormality detection includes an interface that receives a signal representing electrical activity of a patient heart occurring during individual heart cycles of multiple sequential heart cycles. A signal processor decomposes the received signal into multiple signals comprising a heart cycle signal primary wave and one or more heart cycle signal wavelets occurring at corresponding successively higher frequencies. The signal processor determines multiple amplitude representative values of the heart cycle signal primary wave and the one or more heart cycle signal wavelets. A comparator compares the multiple amplitude representative values with corresponding multiple predetermined threshold values to provide comparison indicators.

Abstract: A system for heart performance characterization and abnormality detection detects peaks and at least one of, a valley and a baseline comprising a substantially zero voltage level, of received signal data representing oxygen content of blood in a patient vessel over multiple heart beat cycles. The signal processor determines signal parameters including at least one of, (a) a signal amplitude magnitude between a maximum peak and minimum valley, of the received signal data, (b) a signal amplitude magnitude between a maximum peak and a baseline, of the received signal data and (c) a signal amplitude magnitude between a second highest maximum peak and minimum valley, of the received signal data. The system compares a determined signal parameter or value derived from the determined signal parameter, with a threshold value and generates an alert message associated with the threshold, in response to the comparison.

Abstract: A system determines cardiac output and stroke volume by using non-invasive oximetric signals, such as SPO2 data and waveform, to determine blood flow quantitatively. A non-invasive system determines cardiac output or stroke volume. The system includes an input processor for receiving signal data representing oxygen content of blood of a patient at a particular anatomical location. A computation processor uses the received signal data in calculating a heart stroke volume of the patient comprising volume of blood transferred through the blood vessel in a heart cycle, in response to, a blood volume derived in response to oxygen content of patient blood and at least one factor representing reduction in blood flow volume from a patient heart to the particular anatomical location. An output processor provides data representing the calculated heart stroke volume to a destination device.

Abstract: A catheter has a plurality of sensors and electrodes, wherein the sensors are arranged alternately and spaced apart from each other. A system for continuous measurement and mapping of physiological data may use such a catheter with a coupling unit for insulated coupling of the plurality of sensors with a measurement unit and a mapping unit for mapping values received from the sensors to a predefined matrix.

Abstract: A system for heart performance characterization and abnormality detection includes an interface for receiving signal data representing an electrical signal indicating electrical activity of a patient heart over multiple heart beat cycles. A filter extracts first signal component data in a first selected bandwidth and first heart cycle portion of the received signal data and second signal component data in a different second selected bandwidth and second heart cycle portion of the received signal data. A signal processor uses the received signal data in calculating a ratio of a first value derived from the first signal component data to a second value derived from the second signal component data. A patient monitor in response to the calculated ratio or value derived from the calculated ratio, generates an alert message associated with the threshold.

Abstract: A system for heart performance characterization and abnormality detection includes an interface for receiving signal data representing an electrical signal indicating electrical activity of a patient heart over multiple heart beat cycles. A signal processor uses the received signal data in calculating at least one of, (a) a first signal characteristic value substantially comprising a ratio of a time interval from S wave to T wave, to a time interval from Q wave to S wave and (b) a second signal characteristic value substantially comprising a ratio of a T wave base voltage from a peak of a T wave to a zero base reference voltage, to an R wave base voltage from a peak of an R wave to a zero base reference voltage. A comparator compares at least one of the first and second characteristic values with a threshold value to provide a comparison indicator.

Abstract: A system provides synchronization between different medical signal (e.g., EKG and ICEG signal) acquisition and processing devices. A system synchronizes multiple different patient medical parameter processing devices, using a master clock generator. The master clock generator is adaptively programmable to provide synchronization clocks having frequencies compatible with multiple different medical devices for acquiring patient medical parameter data and for synchronization of processing of medical parameter data concurrently acquired from a single particular patient. The master clock generator is programmed by dividing a clock signal to provide a desired clock frequency in response to received frequency selection command data.

Abstract: A system provides early prediction of heart tissue malfunction and electrophysiological pathology by determining anatomical tissue impedance characteristics for use in medical patient monitoring and treatment decision making. At least one repository of data indicates multiple predetermined expected impedance value ranges for corresponding multiple impedance measurements taken at multiple particular different sites of at least one anatomical organ. An impedance measurement processor automatically determines whether multiple measured impedance values taken at multiple particular different sites of an anatomical organ using an invasive catheter are within corresponding multiple predetermined expected impedance value ranges derived from the at least one repository. An output processor automatically communicates data comprising at least one message to a destination.

Abstract: A medical imaging system adaptively acquires anatomical images. The system includes a synchronization processor for providing a heart rate related synchronization signal derived from a patient cardiac function blood flow related parameter. The synchronization signal enables adaptive variation in timing of acquisition within successive heart cycles of each individual image frame of multiple sequential image frames. An image acquisition device initiates acquisition of anatomical images of a portion of patient anatomy in response to the synchronization signal. A display processor presents images, acquired by the acquisition device and synchronized with the synchronization signal, to a user on a reproduction device. The image acquisition device adaptively selects image pixel resolution of individual image frames of the multiple sequential image frames in response to data identifying a heart cycle segment so that successively acquired image frames have different image pixel resolution within a single heart cycle.

Abstract: A device interface selectively acquires patient physiological parameter data. An acquisition processor acquires physiological data from a patient. A communication processor is coupled to an optical communication pathway for receiving a plurality of optical signals from a source. A conversion processor is electrically coupled to the acquisition processor and communication processor and converts a first optical power signal at a first frequency and received via the optical communication pathway using the communication processor, to a first electrical signal for providing power to said device interface. The conversion processor converts an optical control signal at a second frequency different from the first frequency and received via the optical communication pathway using the communication processor, to a second electrical signal for providing control data to the acquisition processor directing the acquisition processor to acquire at least one physiological parameter from a patient.