Patents by Inventor Hongyu Chen

Hongyu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250129400
    Abstract: The present disclosure provides compositions, reagents, and methods for producing capped, circular RNA molecules, circularized RNA molecules, and in particular, circularized mRNA molecules encoding a polypeptide such as a therapeutic protein.
    Type: Application
    Filed: December 23, 2024
    Publication date: April 24, 2025
    Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Xiao WANG, Hongyu CHEN, Abhishek ADITHAM
  • Publication number: 20250129248
    Abstract: A toughened polyamide composition including a blend of: (A) at least one polyamide; (B) at least one impact modifier; and (C) at least one organic amine; a process for producing the toughened polyamide composition; and articles made from the toughened polyamide compositions.
    Type: Application
    Filed: November 15, 2021
    Publication date: April 24, 2025
    Inventors: Tao Wang, Hongyu Chen, Xilun Weng, Kainan Zhang, Ming Ming, Wenke Miao, Wuye Ouyang
  • Publication number: 20250122342
    Abstract: A curable thermally conductive composition contains: (a) one or more vinyldimethyl terminated polydimethylsiloxane; (b) a silyl-hydride functional polysiloxane that contains at least two silyl-hydride groups per molecule; (c) filler treating agents; (d) 94 to 97 weight-percent thermally conductive fillers that include diamond particles with a Dv50 in a range of 60 to 150 micrometers.
    Type: Application
    Filed: November 23, 2021
    Publication date: April 17, 2025
    Inventors: Chenxu Wang, Yan Zheng, Chao He, Hongyu Chen, Chen Chen
  • Publication number: 20250046315
    Abstract: Provided is an ensemble learning (EL)-based speaker verification method. The method includes: data acquisition and preprocessing; selecting and training a group of basic models, and optimizing model parameters; performing similarity scoring on an acquired pair of speaker feature embedding via the group of basic models; constructing a detection cost function (DCF); generating a weight, and performing weighted fusion on scoring results of the group of basic models based on the weight, to obtain a final ensemble model for speaker verification; based on a near-speaking or far-speaking test scenario of a voice sample, the scenario is distinguished and input into the ensemble model, to obtain a final similarity score after weighted fusion; and determining, based on a threshold, whether there is a same speaker, where if the similarity score is greater than the threshold, it is determined that there is a same speaker.
    Type: Application
    Filed: August 1, 2024
    Publication date: February 6, 2025
    Inventors: Xiaoying SHI, Ruiqi SHU, Kailiang HAO, Fengyu YANG, Hongyu CHEN, Zhenyu JIN
  • Patent number: 12183479
    Abstract: Chemical foaming agents having p-toluenesulfonyl groups. Processes for preparing foamed polyolefin compositions using chemical foaming agents having p-toluenesulfonyl groups. Articles of manufacture containing formed polyolefins prepared using chemical foaming agents having p-toluenesulfonyl groups.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: December 31, 2024
    Assignee: Dow Global Technologies LLC
    Inventors: Gangwei Sun, Hongyu Chen, Mohamed Esseghir, Renhua Fan, Shuo-En Wang
  • Publication number: 20240425674
    Abstract: Embodiments of the present disclosure are directed to a polymeric composition comprising the cross-linked reaction product of an ionomer and a silane crosslinking agent. The ionomer may include an E/X/Y polymer where E is an ethylene monomer, X is ?,?-ethylenically unsaturated carboxylic acid comonomer having 3 to 8 carbons, or its ester, and Y is alkyl acrylate or dicarboxylic acid comonomer. The ionomer comprises from 1 to 30 wt. % of X and from 0 to 40 wt. % of Y. At least a portion of the carboxyl groups of X and optionally Y are neutralized with a metal cation. The silane crosslinking agent has a formula Z((CH2)aSi(OR)b)c. Z is a mono-functional reactive group, R is an alkyl group having 1 to 4 carbon atoms or a hydrogen atom, a is from 1 to 4, b is 3, and c is from 1 to 2.
    Type: Application
    Filed: November 3, 2022
    Publication date: December 26, 2024
    Applicant: Dow Global Technologies LLC
    Inventors: Xiaomei Song, Hongyu Chen, Xuejun Liu
  • Patent number: 12163016
    Abstract: The present disclosure provides a crosslinked polymeric composition. The crosslinked polymeric composition contains (A) a silane functionalized ethylene-based polymer and (B) inorganic hollow microspheres having (i) a D90 particle size from 10 ?m to 100 ?m, (ii) a crush strength from 17 MPa to 140 MPa, and (iii) a density from 0.10 g/cc to 0.40 g/cc. The crosslinked polymeric composition has a tensile strength from 11 MPa to 40 MPa and a tensile elongation from 12% to 100%.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: December 10, 2024
    Assignee: Dow Global Technologies LLC
    Inventors: Chao He, Wenke Miao, Xianmin Xu, Mohamed Esseghir, Xiaoxing Miao, Hongyu Chen
  • Publication number: 20240392311
    Abstract: Disclosed herein are modified mRNAs with poly(A) tails containing one or more additional poly-A tails or 5? caps, which may be made by ligation of nucleic acids onto the 3? terminal end or 5? terminal end of an RNA, respectively. Also provided are compositions comprising one or more modified mRNAs provided herein, and methods of using said compositions for therapeutic or agricultural applications.
    Type: Application
    Filed: July 17, 2024
    Publication date: November 28, 2024
    Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Xiao WANG, Hongyu CHEN, Abhishek ADITHAM, Jianting GUO
  • Publication number: 20240368401
    Abstract: Toughened polyamide composition including: (a) at least one polyamide; (b) at least one toughener component; and (c) at least one siloxane-based component having a viscosity of 1 mm2/s-100,000 mm2/s providing toughened polyamide composition with good impact strength; process for producing the toughened polyamide composition; and articles made from the toughened polyamide composition.
    Type: Application
    Filed: November 15, 2021
    Publication date: November 7, 2024
    Inventors: Tao Wang, Hongyu Chen, Xilun Weng, Kainan Zhang, Ming Ming, Wenke Miao, Wuye Ouyang, Andong Liu
  • Publication number: 20240343902
    Abstract: Polyester polymer compositions are described containing one or more nucleating agents and optionally reinforcing fibers. The polyester polymer, for instance, can be poly butylene terephthalate. The polymer composition is particularly formulated in order to be substantially transparent at specific wavelengths of light. Consequently, the polyester polymer composition is well suited for use in laser transmission welding in which a laser beam passes through the polymer composition and forms a weld on an adjoining surface. In one aspect, a black pigment masterbatch can be added to the composition for further improving the transparency properties.
    Type: Application
    Filed: August 13, 2021
    Publication date: October 17, 2024
    Inventors: Hongyu Chen, Fangfang Tao, Wouter Gabrielse, Dirk Zierer
  • Patent number: 12116447
    Abstract: An adhesive composition including a reaction mixture of: (A) at least one isocyanate-containing compound; (B) at least one polyol compound; and (C) a copolymerized crystalline latent catalyst; a process for making the above adhesive composition; and a laminate structure made using the above adhesive composition.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: October 15, 2024
    Assignee: Dow Global Technologies LLC
    Inventors: ChenYan Bai, Hongyu Chen, Thorsten Schmidt, Yingfeng Yu, Haijun Dong
  • Patent number: 12116511
    Abstract: A process for preparing a waterborne dispersion of a silicone pressure sensitive adhesive base includes the use of a solventless polyorganosiloxane pellet containing a polyorganosilicate resin and a polyorganosiloxane gum. The waterborne dispersion of the silicone pressure sensitive adhesive base can be combined with a free radical initiator, and dried and cured to form a silicone pressure sensitive adhesive.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: October 15, 2024
    Assignees: Dow Silicones Corporation, Dow Global Technologies LLC
    Inventors: Yunlong Guo, Hongyu Chen, David L. Malotky, Bin Chen, Zhihua Liu, Xiucuo Li, Yan Zhou, Wenjie Chen, Li Ding, Qiangqiang Yan
  • Publication number: 20240336752
    Abstract: Composite articles that can resist discoloration or color changes are described. In some instances, the composite articles can include a compounded material that is substantially free of an antioxidant that changes from a first color to a second color upon exposure to an environment comprising an oxidizing agent. The composite articles can be flame retardant and may provide sound reduction as well.
    Type: Application
    Filed: January 8, 2024
    Publication date: October 10, 2024
    Inventors: Peng Cheng, Hongyu Chen, Liqing Wei, Ruomiao Wang
  • Publication number: 20240317911
    Abstract: A process to form a composition, said process comprising at least the following steps A) and B): A) mixing together at least the following components a and b to form a first composition: a) the “anhydride-functionalized olefin-based polymer”, and b) at least one multifunctional epoxy compound comprising at least two epoxy groups, or at least one oxetane compound comprising at least one oxetane group; B) exposing the first composition to moisture to form the crosslinked olefin-based polymer. Also, related is first compositions and crosslinked compositions.
    Type: Application
    Filed: September 19, 2021
    Publication date: September 26, 2024
    Inventors: Chao He, Hongyu Chen, Wanfu Ma, Xin Tan, Wuye Ouyang, Allan Walter Mclennaghan, Juan C. Tuberquia
  • Publication number: 20240301188
    Abstract: The present invention relates to a composition comprising an aqueous dispersion of a) polyisobutylene particles; and b) polyolefin particles, which are polyethylene or polypropylene particles, wherein the weight-to-weight ratio of the polyisobutylene particles to the polyolefin particles is in the range of from 20:80 to 80:20. The composition of the present invention is useful for making coatings on paper or paperboard substrates with excellent moisture barrier and tack properties.
    Type: Application
    Filed: April 15, 2021
    Publication date: September 12, 2024
    Inventors: Hongyu Chen, Yunlong Guo, David L. Malotky, Alan M. Piwowar, Xiaomei Song, Qiangqiang Yan
  • Publication number: 20240301250
    Abstract: A process for preparing a waterborne dispersion of a silicone pressure sensitive adhesive base includes the use of a solventless polyorganosiloxane pellet containing a polyorganosilicate resin and a polyorganosiloxane gum. The waterborne dispersion of the silicone pressure sensitive adhesive base can be combined with a free radical initiator, and dried and cured to form a silicone pressure sensitive adhesive.
    Type: Application
    Filed: April 9, 2021
    Publication date: September 12, 2024
    Inventors: Yunlong Guo, Hongyu Chen, David L. Malotky, Bin Chen, Zhihua Liu, Xiucuo Li, Yan Zhou, Wenjie Chen, Li Ding, Qiangqiang Yan
  • Patent number: 12077657
    Abstract: A composition comprising at least the following components: A) an olefin multi-block copolymer; and B) a silicone rubber that comprises pendant vinyl groups, and optionally comprises terminal vinyl groups.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: September 3, 2024
    Assignee: Dow Global Technologies LLC
    Inventors: Haiyang Yu, Xiaolian Hu, Hongyu Chen, Kyle G. Kummer
  • Publication number: 20240279437
    Abstract: The present disclosure relates to an encapsulant film made from a curable composition comprising: (A) a polyolefin polymer; (B) an organic peroxide; (C) a silane coupling agent; and (D) a co-agent comprising a monocyclic organosiloxane of formula (I).
    Type: Application
    Filed: October 31, 2017
    Publication date: August 22, 2024
    Applicant: Dow Global Technologies LLC
    Inventors: Yunfeng Yang, Chao He, Weiming MA, Hongyu Chen, Yabin Sun, Kainan Zhang, Jeffrey M. Cogen, Timothy J. Person, Yuyan Li, Hong Yang
  • Publication number: 20240271016
    Abstract: A composition for forming a release coating comprises (A) an organopolysiloxane having an average of at least two carbinol functional groups per molecule. The organopolysiloxane (A) is present in the composition in an amount of from 50 to 99 wt. % based on the total weight of the composition. The composition further comprises (B) a polyisocyanate. The release coating formed with the composition is not a foam. A release coating formed with the composition is also disclosed. In addition, a method of preparing a coated substrate comprising a release coating disposed on a substrate, as well as the coated substrate formed in accordance with the method, are disclosed.
    Type: Application
    Filed: May 24, 2021
    Publication date: August 15, 2024
    Inventors: Yu CHEN, Fuming HUANG, Shi PAN, Jiguang ZHANG, Hongyu CHEN, Zhihua LIU
  • Patent number: D1062706
    Type: Grant
    Filed: August 16, 2023
    Date of Patent: February 18, 2025
    Assignee: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.
    Inventors: Geshi Zhu, Mingfei Chen, Hongyu Chen