Abstract: The present disclosure provides polypeptide conjugates comprising GLP-1 receptor agonist and a peptide linker, and pharmaceutical compositions comprising the same. Methods of using such for treating diseases are also provided.

Abstract: Examples of message transmission methods and apparatus are described. In one example, a message transmission method includes that a first network device receives a first message from a terminal device, where the first message includes a resume cause value and an integrity check code. The integrity check code is generated based on the resume cause value, the terminal device is in an inactive state, and the resume cause value is a resume cause indicated by a higher layer or a radio resource control (RRC) layer. The first network device sends a second message to a second network device, where the second message includes the resume cause value and the integrity check code. The second network device is a network device that stores a context of the terminal device.

Abstract: An amplifier device may include an amplifier transistor and having harmonic termination circuitry and an output impedance network, such as an output T network, coupled to the output of the amplifier transistor. The amplifier device may be configured as an inverted F class amplifier having an operational frequency range with a center frequency of less than or equal to around 2.6 GHz. The harmonic termination circuitry and output impedance network may be configured to create a short circuit or near short circuit at the amplifier transistor output for third harmonic frequencies of the center frequency of the amplifier transistor and to create an open circuit or near open circuit at the amplifier transistor output for second harmonic frequencies of the center frequency. The output impedance network may be configured to increase the output impedance at the center frequency and reduce signal loss for the amplifier device.

Abstract: A curable polyolefin composition is provided. The curable polyolefin composition comprises: (A) a polyolefin having at least two aliphatic unsaturated bonds per molecule and having a viscosity at 25° C. of less than 2,500 mPa·s; (B) an organopolysiloxane having at least two silicon atom-bonded hydrogen atoms per molecule; (C) a hydrosilylation reaction catalyst; and (D) a thermal conductive filler. The curable polyolefin composition can be cured to form a soft material with good thermal conductive properties.

Abstract: A continuous solid organic matter pyrolysis polygeneration system and method for using the system is disclosed. The pyrolysis polygeneration system mainly includes a processing system, a drying furnace, a pyrolysis furnace, a cooling furnace, a tail gas treatment system, and a gas treatment system and a protective gas circulation system cooperate with each other to realize the multi-level rational utilization of energy, and are suitable for the continuous and rapid pyrolysis and carbonization of various solid organic matter in the actual production. While realizing the polygeneration of coke, wood vinegar and tar, the maximum utilization of overall heat is realized through process optimization.

Abstract: Disclosed is a testing device and method for a service life of an air-conditioning compressor of a new energy vehicle running with pure gas. The testing device includes an alternative refrigeration system, a measurement and control system, and a testing environment room. A main refrigeration cycle system of the alternative refrigeration system runs with pure gas, gas of a testing compressor is discharged via a discharge throttle valve, and then enters a suction end via a suction throttle valve and an electronic expansion valve, and since there is no phase change, a heat exchange amount is small; adjustable ranges of the discharge throttle valve, the suction throttle valve and the electronic expansion valve are wide; and based on the system structure, a small refrigeration system can be used to test a compressor having high cooling capacity, and the system can quickly achieve a target working condition with a small amount of refrigerant.

Abstract: The present disclosure relates to the technical field of chemical engineering, and specifically discloses a method for removing oxygenated compounds from a Fischer-Tropsch oil having a high carbon number. A reaction-extraction combined process is used in this method for removing oxygenated compounds from a Fischer-Tropsch oil having a high carbon number, wherein the Fischer-Tropsch oil (C5-C20) is firstly subjected to alkaline washing with an alkaline aqueous solution to convert acidic substances into water-soluble salts. The Fischer-Tropsch oil is subjected to a primary extraction with a carbonate-based extractant to remove alcohols and esters therein, and subsequently subjected to a secondary extraction with propylene carbonate to remove ketones and aldehydes impurities therein, thereby removing oxygenated compounds in the Fischer-Tropsch oil. After extraction, the content of the oxygenated compounds in the Fischer-Tropsch oil may be down to 1-60 ppm, and the yield of oil product may be kept 90% or more.

Abstract: An ion-modified microwave dielectric ceramic is provided and a chemical formula thereof is Zn0.15Nb0.3[Ti1-x(W1/3Zr1/2)x]0.55O2. In the chemical formula, x is in a range of 0.01 to 0.03. The ion-modified microwave dielectric ceramic includes the following components in parts by weight: 12.58-12.67 parts of ZnO, 41.11-41.39 parts of TiO2, 43.93-45.14 parts of Nb2O5, 0.44-1.31 parts of WO3, and 0.35-1.05 parts of ZrO2. A preparation method of the ion-modified microwave dielectric ceramic can be applied to different industrial requirements, such as electronic components, communication equipment, and microwave components; and the obtained ion-modified microwave dielectric ceramic expands a practical value of a Zn0.15Nb0.3Ti0.55O2 series microwave dielectric ceramic in electronic ceramic manufacturing.

Abstract: Provided are a display panel including multiple scan lines located in the display region and gate drive unit groups located in a non-display region. The gate drive unit groups include at least one first gate drive unit group and at least one second gate drive unit group. The first gate drive unit group includes multiple cascaded first gate drive units. The second gate drive unit group includes multiple cascaded second gate drive units. The first gate drive units and the second gate drive units are connected to different scan lines. A first period during which a first gate drive unit at the first stage transmits an effective level signal to a scan line and a second period during which a second gate drive unit at the first stage transmits an effective level signal to a scan line overlap, overlap duration is t, and t>0.

Abstract: A radio resource configuration adjustment method includes detecting, by user equipment, an overheating problem or that the overheating problem is alleviated, and sending, by the user equipment, a first message to a network device, where the first message is used to notify the network device that the overheating problem occurs in the user equipment or the overheating problem is alleviated; receiving, by the user equipment, a response message sent by the network device, where the response message is used to instruct the user equipment to perform one of the following operations, and the operations include deactivating a secondary serving cell, activating a secondary serving cell, releasing a secondary serving cell, and adding a secondary serving cell; and deactivating, by the user equipment, a secondary serving cell, or activating a secondary serving cell, or releasing a secondary serving cell, or adding a secondary serving cell according to the response message.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: This invention relates to a multi-element membrane separator and separation method based on spiral-wound membrane elements. It includes a membrane housing, spiral-wound membrane elements, and baffles on both sides of the membrane housing, designed to secure the spiral-wound membrane elements. The permeate tubes of the spiral-wound membrane elements are connected to the openings in the perforated plates. Sealing rings are respectively provided at the connections of the permeate tubes and the perforated plate openings. This multi-element membrane separator enables a more compact arrangement of membrane elements, reducing the footprint of the membrane separation device. It also reduces the use of materials such as membrane housing, pipelines, and connecting fittings, thereby lowering equipment costs and the difficulty of membrane device assembly.

Abstract: A computer system includes physical memory devices of different types that store randomly-accessible data in a main memory of the computer system. In one approach, data is stored in memory at one or more logical addresses allocated to an application by an operating system. The data is physically stored in a first memory device of a first memory type (e.g., NVRAM). The operating system determines an access pattern for the stored data. In response to determining the access pattern, the data is moved from the first memory device to a second memory device of a different memory type (e.g., DRAM).

Abstract: An ion-modified microwave dielectric ceramic is provided and a chemical formula thereof is Zn0.15Nb0.3[Ti1-x(W1/3Zr1/2)x]0.55O2. In the chemical formula, x is in a range of 0.01 to 0.03. The ion-modified microwave dielectric ceramic includes the following components in parts by weight: 12.58-12.67 parts of ZnO, 41.11-41.39 parts of TiO2, 43.93-45.14 parts of Nb2O5, 0.44-1.31 parts of WO3, and 0.35-1.05 parts of ZrO2. A preparation method of the ion-modified microwave dielectric ceramic can be applied to different industrial requirements, such as electronic components, communication equipment, and microwave components; and the obtained ion-modified microwave dielectric ceramic expands a practical value of a Zn0.15Nb0.3Ti0.55O2 series microwave dielectric ceramic in electronic ceramic manufacturing.

Abstract: Curable polyolefin composition comprising: (A) polyolefin having at least two aliphatic unsaturated bonds per molecule; (B) wax with melting point of 30 to 100° C.; (C) organopolysiloxane having at least two silicon atom-bonded hydrogen atoms per molecule; and (D) catalytic amount of hydrosilylation reaction catalyst, wherein content of component (A) is 20 to 80 mass %, content of component (B) is 10 to 75 mass %, and content of component (C) is 1 to 20 mass %, each based on the total mass of components (A) to (D). The composition can be cured to form a cured product capable of storing and releasing thermal energy, and preventing the wax leaking/pumping out during heat cycling.

Abstract: Antibodies binding to human claudin 18.2 (CLDN 18.2) and bispecific antibodies binding to both human CLDN 18.2 and PD-L1, pharmaceutical compositions comprising such, and methods of using such for treating target diseases including cancer.

Abstract: To achieve a method for producing a carbonic ester at a high yield by a simple process while suppressing formation of by-products, for example, a method for producing an aliphatic carbonic ester. The above problem is solved by a method for producing a carbonic ester, the method including a carbonic ester formation reaction in which an alcohol and carbon dioxide are reacted in the presence of an aromatic nitrile compound and a catalyst, wherein the water content in the alcohol used in the carbonic ester formation reaction is 0.10% by mass or less.

Abstract: The present disclosure discloses an automated particle implantation system comprising an active system and a passive system. The active system may be configured to obtain a scanning image of a scanned object. The active system may be also configured to plan a radioactive particle implantation treatment according to the scanning image and obtain a radioactive particle implantation treatment planning result. The active system may be further configured to control the passive system to execute a radioactive particle implantation operation based on the radioactive particle implantation treatment planning result. The present disclosure further discloses a particle chain generating mechanism. The present disclosure further discloses a puncture device terminal.

Abstract: The present disclosure relates to a method and apparatus for knowledge graph construction, storage medium and electronic device. The method for knowledge graph construction, comprises: identifying an entity concept from a title text of a target web page and at least one entity corresponding to the entity concept from a body text of the target web page; constructing a syntax parse tree of the title text based on syntax parse rules of a language to which the title text belongs, and determining, from the syntax parse tree, a modifier for modifying the entity concept; and generating a knowledge graph based on the entity concept, the modifier, and the at least one entity. Through the solution of the present disclosure, knowledge graphs with high accuracy and high recall rates are constructed without structured processing on target web pages.