Abstract: Provided is an oral Pt(IV) anticancer prodrug containing a 3-bromopyruvate as an axial ligand, with a molecular formula of cis,trans,cis-[Pt(1R,2R-diaminocyclohexane)(OH)(3-bromopyruvate)(C2O4)]. It is a prodrug of oxaliplatin and 3-bromopyruvic acid is a small molecular glycolysis inhibitor. The prodrug is able to simultaneously act on DNA replication and glycolytic pathways of cancer cells, giving full play to the advantage of double-acting targets. The oral Pt(IV) anticancer prodrug is synthesized by using oxaliplatin as a starting material, performing axial oxidation with H2O2 and neutralizing the oxidized product with 3-bromopyruvic acid.

Abstract: Provided in the present invention are an entry information processing method, a terminal device, and a computer-readable storage medium. The method comprises: in response to a slide operation with respect to entry information, determining a target event corresponding to the slide operation, then, when the slide distance of the slide operation reaches a first threshold, activating the target event, and then, when the slide distance reaches a second threshold, processing the entry information according to the target event, where the second threshold is greater than the first threshold.

Abstract: A polyolefin-and-poly (2-alkyl-2-oxazoline) formulation comprising (A) an olefin-based (co) polymer, (B) a poly (2-alkyl-2-oxazoline) (co) polymer, and (C) an antioxidant. Also a method of making the composition; a crosslinked polyolefin product made by curing the composition; manufactured articles comprising a shaped form of the inventive formulation or product; and methods of using the inventive formulation, product, or articles.

Abstract: The present invention provides a foamable cleaning agent for an air intake system, comprising: a) 6 to 10 wt. % of ?-sulfo-fatty acid methyl ester salt and/or alpha-olefin sulfonate; b) 6 to 10 wt. % of alkyl polyglucoside APG2000; c) 1.5 to 2.5 wt. % of coconut oil fatty acid diethanolamide and/or lauric diethanol amide LDEA; and d) 5 to 15 wt. % of water; based on the total weight of the foamable cleaning agent, also provided are an aerosol product comprising: an aerosol can containing the foamable cleaning agent, and a spraying device, through which the foamable cleaning agent can be sprayed out as a foam; and a method for preparing the aerosol product, a method of cleaning air intake system with the aerosol product, and a use of the foamable cleaning agent or the aerosol product for cleaning air intake system.

Abstract: A communication method and apparatus are provided. The method includes: A first node determines a sending time point of a second PDCP PDU based on first sending status information from a second node, where the first sending status information is associated with a first PDCP PDU, so that the first node can adjust the sending time point of the second PDCP PDU based on a sending situation of the first PDCP PDU, to avoid too many packet losses caused when a MAC PDU of the second PDCP PDU is not completely sent in a timely manner due to splitting and concatenation, so as to improve reliability of a synchronous data transmission mechanism in an NR system, and improve resource utilization.

Abstract: Provided is a cleaning composition contained in an aerosol spray can, methods of making and using the cleaning composition, which comprises: a liquid cleaning mixture, comprising: a) a solvent selected from the group consisting of isohexane, isoheptane, and n-heptane and mixtures thereof; b) a de-aromatized hydrocarbon solvent having 7 to 8 carbon atoms in its molecule; c) a branched aliphatic alkane having 10 to 11 carbon atoms; d) from 5 to 15 parts by weight of ethanol, e) from 1 to 15 parts by weight of isopropanol, f) from 1 to 10 parts by weight of acetone, and g) from 0.01 to 0.2 parts by weight of iso-tridecanol polyoxyethylene ether having a HLB value of 12 to 13, and a gas propellant.

Abstract: The present application discloses a product quality prediction method based on a dual-channel information complementary fusion stacked auto-encoder. According to the present method, the design of a stacked auto-encoder is firstly adopted, and the input data information is received and trained to obtain the information of a hidden layer of the stacked auto-encoder. Then, outside the stacked auto-encoder, a structure of an information complementary fusion module and a down-to-top and top-to-down dual-channel information fusion layer is designed, which can use the information of the hidden layer inside the stacked auto-encoder and transmit the information in two directions. Furthermore, the output value and output information of the module are calculated through a gating module and is subjected to weighted fusion to obtain a final product quality prediction result.

Abstract: Disclosed in the present disclosure is a double-deck multi-span bridge construction method. According to the double-deck bridge construction method of the present disclosure, construction is carried out by using a method of disassembling a support jig frame in a graded and span-separated mode, an upper chord jig frame and a lower chord jig frame can be used in a recycle manner, and construction costs are reduced. In addition, a construction period of building the support jig frame is shortened, and other construction operations can be synchronously carried out on a span in which the jig frame is disassembled, for example, fire retardant coating construction can be carried out on a mounted bridge deck after the jig frame is disassembled, and the construction period of a double-deck multi-span bridge is effectively shortened.

Abstract: A display device driver and a driving method thereof are provided. The display device driver includes a display panel, a source driver, and a timing control chip, wherein the display panel is configured to present at least two load types of display images, the source driver is signally connected to the display panel, and the timing control chip includes a data detection module and a data processing module.

Abstract: A computer system includes physical memory devices of different types that store randomly-accessible data in a main memory of the computer system. In one approach, an operating system allocates memory from a namespace for use by an application. The namespace is a logical reference to physical memory devices in which physical addresses are defined. The namespace is bound to a memory type. In response to binding the namespace to the memory type, the operating system adjusts a page table to map a logical memory address in the namespace to a memory device of the memory type.

Abstract: The present disclosure relates to a leather coating composition comprising or consisting of a hydrosilylation curable silicone elastomer composition designed to be used as a topcoat for a synthetic leather material, particularly a silicone-based synthetic leather composite material. A silicone coating as a topcoat for a synthetic leather material which is the cured product of the composition, methods of making the topcoat, synthetic leather material utilizing same and uses of the synthetic leather material products are also disclosed. The topcoat is designed to provide a highly crosslinked silicone matrix containing silicon-free organic micro-particles to minimize or at least decrease change in gloss after abrasion.

Abstract: An interaction method, an interaction apparatus, and an electronic device are provided. The method includes: determining, in response to detecting a predefined size transformation operation, target transformation information of a target video based on whether a current size of the target video is a preset anchor point size, where the target video is a video played in a video play area; and transforming the target video based on the target transformation information, and playing the transformed target video.

Abstract: Provided are a method, a system and an electronic device for implementing flexible graphics enhancement and execution. For example, a flexible graphics enhancement and execution component can be an integrated element of a graphics application programming interface (API) that allows a visual effect of style to be added to the 3D graphics rendered from a mobile game. The techniques can include intercepting an initial function call, where the initial function call is associated with a graphics API rendering an image for an application. Then, a custom function can be automatically generated, based on the intercepted initial function call. A pointer associated with the generated custom function can be returned to the application, where the custom function modifies an output from the graphics API to add a visual effect to a three-dimensional (3D) rendered image of the application. The graphics API can be an Open Graphics Library (OpenGL) API.

Abstract: The present invention provides compounds of Formula I which can be used as macrophage migration inhibitory factor (MIF) inhibitors; methods for the production of the compounds of the invention; pharmaceutical compositions comprising the compounds of the invention; as well as uses and methods for treating a disease mediated by MIF by administering the compounds of the invention.

Abstract: The present disclosure relates to an information distribution method, apparatus, and computer readable storage medium, which relates to the field of information processing. The information distribution method includes: determining a recommended value of a target indicator corresponding to a user based on a historical indicator of information historically distributed by the user and a historical indicator of a category to which the user belongs, wherein an indicator is determined based on resources gained and consumed through distributed information; recommending the recommended value of the target indicator to the user; determining target recipients of target information to be distributed by the user based on a target indicator input by the user, wherein the target indicator input by the user is determined based on the recommended value of the target indicator by the user; and sending the target information to the target recipients.

Abstract: A terminal device determines that local first system information is abnormal in the case of any of the following: a quantity of times of sending first signaling is greater than or equal to a first preset threshold within first preset duration; a time length in which a first service is unavailable is greater than or equal to a second preset threshold; a change trend of a tag value of a same system information block is abnormal; or a quantity of changes in a tag value of a same system information block is greater than or equal to a third preset threshold within second preset duration. The terminal device receives, from an access network device, second system information that is used to update the local first system information. Therefore, the terminal device can determine as soon as possible whether the terminal device is being attacked by a rogue base station.

Abstract: Systems and methods of rendering effects are described herein. A computing device can receive a user selection of an effect to be applied during gameplay of a computer game. The computing device can initiate a framework with which to apply the effect during the gameplay. The computing device can determine scenes during the gameplay to apply the effect through the framework. The computing device can determine graphical elements in the scenes that correspond to non-user interface elements through the framework. The computing system can apply the effect to the graphical elements through the framework.

Abstract: A battery pack includes a first battery cell, a second battery cell, and a third battery cell. A positive electrode active substance of each battery cell is composed of lithium iron phosphate and a low-temperature additive. The low-temperature additive is selected from compounds containing at least two carbonyl groups, which are conjugated with an unsaturated structure or an atom having lone-pair electrons connected with the carbonyl groups, and a discharging cut-off voltage of the battery pack at a low temperature has the following rules: discharging cut-off voltages V1, V2, and V3 of the first battery cell, second battery cell, and third battery cell range from 1.95V to 2.1V, from 1.8 V to 2.0V, from 1.6V to 1.9V, respectively, and V1, V2, and V3 satisfy a relationship of V1>V2>V3.

Abstract: A system for defending against a side channel attack. The system includes a reuse distance buffer configured to measure one or more reuse distances for a microarchitecture block according to information of marker candidates and information of target events of a microarchitecture block; and a defense actuator configured to determine existence of a side channel attack in the microarchitecture block according to the one or more reuse distances for the microarchitecture block.

Abstract: A comprehensive water protection device, which is arranged on a water pipeline between a water pipeline inlet and downstream water equipment, includes a control unit, a water circuit valve installed on the water pipeline, a flow meter, a pressure gauge, and at least one of: a water quality detection probe; and a water leakage probe, which is used to monitor the water leakage point in the water pipeline and the downstream water equipment. The water circuit valve, the flow meter, the pressure gauge, the water quality detection probe, and the water leakage probe are connected to the control unit; and the flow meter, the pressure gauge, the water quality detection probe, and the water leakage probe are set in the water pipeline.