Patents by Inventor Hosheng Tu

Hosheng Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200155349
    Abstract: Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
    Type: Application
    Filed: November 22, 2019
    Publication date: May 21, 2020
    Inventors: David Steven Haffner, Gregory T. Smedley, Hosheng Tu, Thomas W. Burns
  • Patent number: 10485701
    Abstract: Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: November 26, 2019
    Assignee: Glaukos Corporation
    Inventors: David Steven Haffner, Gregory T. Smedley, Hosheng Tu, Thomas W. Burns
  • Publication number: 20190321225
    Abstract: A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.
    Type: Application
    Filed: February 19, 2019
    Publication date: October 24, 2019
    Inventors: Gregory T. Smedley, David Steven Haffner, Barbara A. Niksch, Hosheng Tu, Thomas W. Burns, Richard A. Hill
  • Patent number: 10406029
    Abstract: Ocular implants, delivery devices and methods for treating ocular disorders are disclosed. One method involves inserting an implant on one side of an eye. The implant has an anchor on a distal end portion and an outlet opening that is disposed proximal of the anchor. The implant is advanced across the eye to the other side of the eye. The anchor is inserted into eye tissue on the other side of the eye. A therapeutic agent is eluted using the implant.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: September 10, 2019
    Assignee: Glaukos Corporation
    Inventors: Hosheng Tu, Jason Artof, David Steven Haffner, Gregory T. Smedley, Barbara A. Niksch
  • Patent number: 10285856
    Abstract: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: May 14, 2019
    Assignee: Glaukos Corporation
    Inventors: Hosheng Tu, David Steven Haffner, Gregory T. Smedley, Barbara A. Niksch, Morteza Gharib, Thomas W. Burns, Richard Lindstrom
  • Publication number: 20190076282
    Abstract: A gastric space filler device for treating obesity in a patient by reducing the stomach volume comprising an inflatable space filler and a safety element secured to the space filler, wherein the safety element yields a noticeable signal for causing removal of the space filler.
    Type: Application
    Filed: April 2, 2018
    Publication date: March 14, 2019
    Inventors: Rodolfo C. Quijano, Hosheng Tu, Andrew H. Cragg, Bobby Purkait
  • Publication number: 20190030302
    Abstract: Systems and methods for treating ocular disorders are disclosed. One system has a delivery instrument, with a non-linear axis, configured to be inserted into an anterior chamber of an eye and moved to a location proximate a physiologic outflow pathway of the eye. The delivery instrument carries an implant that has a distal end sized for insertion into tissue such that aqueous humor drains from the anterior chamber to the physiologic outflow pathway. One method involves inserting a non-linear portion of a delivery device into the anterior chamber to position an implant within the eye. Another method involves using a delivery device with a curved distal portion to implant an implant at a location communicating with the physiologic outflow pathway. The delivery can be through a corneal incision and the implant can comprise a drug.
    Type: Application
    Filed: May 29, 2018
    Publication date: January 31, 2019
    Inventors: David Steven Haffner, Gregory T. Smedley, Hosheng Tu, Barbara A. Niksch, Richard A. Hill, Olav B. Bergheim
  • Publication number: 20180161205
    Abstract: Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye. The implant is implanted into eye tissue adjacent the anterior chamber such that a proximal end of the implant resides in the anterior chamber following implantation. A therapeutic agent is eluted from the implant into the eye. Desirably, the release of the therapeutic agent from the implant is controlled. The controlled release of the therapeutic agent can be at a chosen rate and/or for a selected duration which can be episodic or periodic. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension.
    Type: Application
    Filed: October 16, 2017
    Publication date: June 14, 2018
    Inventors: Hosheng Tu, Barbara A. Niksch, David S. Haffner, Gregory T. Smedley, Olav B. Bergheim, Morteza Gharib, Richard A. Hill, Thomas W. Burns
  • Patent number: 9987472
    Abstract: Systems and methods for treating ocular disorders are disclosed. One system has a delivery instrument, with a non-linear axis, configured to be inserted into an anterior chamber of an eye and moved to a location proximate a physiologic outflow pathway of the eye. The delivery instrument carries an implant that has a distal end sized for insertion into tissue such that aqueous humor drains from the anterior chamber to the physiologic outflow pathway. One method involves inserting a non-linear portion of a delivery device into the anterior chamber to position an implant within the eye. Another method involves using a delivery device with a curved distal portion to implant an implant at a location communicating with the physiologic outflow pathway. The delivery can be through a corneal incision and the implant can comprise a drug.
    Type: Grant
    Filed: December 27, 2010
    Date of Patent: June 5, 2018
    Assignee: GLAUKOS CORPORATION
    Inventors: Hosheng Tu, Gregory T. Smedley, David Steven Haffner, Barbara A. Niksch, Richard A. Hill, Olav B. Bergheim
  • Patent number: 9962276
    Abstract: A gastric space filler device for treating obesity in a patient by reducing the stomach volume comprising an inflatable space filler and a safety element secured to the space filler, wherein the safety element yields a noticeable signal for causing removal of the space filler.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: May 8, 2018
    Assignee: ReShape Medical LLC
    Inventors: Rodolfo C. Quijano, Hosheng Tu, Andrew H. Cragg, Bobby Purkait
  • Publication number: 20180036172
    Abstract: Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
    Type: Application
    Filed: March 20, 2017
    Publication date: February 8, 2018
    Inventors: David Steven Haffner, Gregory T. Smedley, Hosheng Tu, Thomas W. Burns
  • Patent number: 9789001
    Abstract: Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye. The implant is implanted into eye tissue adjacent the anterior chamber such that a proximal end of the implant resides in the anterior chamber following implantation. A therapeutic agent is eluted from the implant into the eye. Desirably, the release of the therapeutic agent from the implant is controlled. The controlled release of the therapeutic agent can be at a chosen rate and/or for a selected duration which can be episodic or periodic. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: October 17, 2017
    Assignee: DOSE MEDICAL CORPORATION
    Inventors: Hosheng Tu, Barbara A. Niksch, David S. Haffner, Gregory T. Smedley, Olav B. Bergheim, Morteza Gharib, Richard A. Hill, Thomas W. Burns
  • Publication number: 20170273829
    Abstract: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
    Type: Application
    Filed: February 6, 2017
    Publication date: September 28, 2017
    Inventors: Hosheng Tu, David Steven Haffner, Gregory T. Smedley, Barbara A. Niksch, Morteza Gharib, Thomas W. Burns, Richard Lindstrom
  • Patent number: 9597230
    Abstract: Intraocular implants and delivery instruments are disclosed for treating ophthalmic conditions and ocular disorders, such as glaucoma. The implants are configured to extend between the anterior chamber of the eye and a fluid outflow path or physiologic outflow pathway, such as Schlemm's canal, of the eye for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The implants can have features for anchoring the implant into the physiologic outflow pathway as well as preventing the walls of the physiologic outflow pathway from closing the outlet of the implants. The delivery instruments can be steerable so as to make implantation easier. Additionally, the delivery instruments can be configured to hold a plurality of implants so that multiple implants can be implanted through one incision without removing the delivery instrument from the incision between serial implantations.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: March 21, 2017
    Assignee: GLAUKOS CORPORATION
    Inventors: David Steven Haffner, Gregory T Smedley, Hosheng Tu, Thomas W. Burns
  • Patent number: 9572963
    Abstract: An embodiment of a system for shunting aqueous humor from an anterior chamber of an eye includes an implant having an elongated body made of biocompatible material and a delivery device. At least a portion of the elongated body is implantable between a sclera and a ciliary body while the elongated body resides entirely within the confines of the sclera and a cornea with the proximal end of the implant being configured to reside within an anterior chamber angle and a lumen extending from at least one inlet port of the implant, through at least a portion of the elongated body, to one or more outlet ports of the implant so as to drain fluid from the anterior chamber toward a choroid of the eye. The delivery device includes an elongated member with a curved distal end portion to deliver the implant using an ab interno procedure.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: February 21, 2017
    Assignee: Glaukos Corporation
    Inventors: Hosheng Tu, Barbara A. Niksch, David Steven Haffner, Gregory T. Smedley, Richard A. Hill, Olav B. Bergheim
  • Patent number: 9561131
    Abstract: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: February 7, 2017
    Assignee: Glaukos Corporation
    Inventors: Hosheng Tu, David Steven Haffner, Gregory T. Smedley, Barbara A. Niksch, Morteza Gharib, Thomas W. Burns, Richard Lindstrom
  • Publication number: 20160175151
    Abstract: Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye. The implant is implanted into eye tissue adjacent the anterior chamber such that a proximal end of the implant resides in the anterior chamber following implantation. A therapeutic agent is eluted from the implant into the eye. Desirably, the release of the therapeutic agent from the implant is controlled. The controlled release of the therapeutic agent can be at a chosen rate and/or for a selected duration which can be episodic or periodic. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension.
    Type: Application
    Filed: June 29, 2015
    Publication date: June 23, 2016
    Inventors: Hosheng Tu, Barbara A. Niksch, David S. Haffner, Gregory T. Smedley, Olav B. Bergheim, Morteza Gharib, Richard A. Hill, Thomas W. Burns
  • Publication number: 20160100983
    Abstract: Ocular implants, delivery devices and methods for treating ocular disorders are disclosed. One method involves inserting an implant on one side of an eye. The implant has an anchor on a distal end portion and an outlet opening that is disposed proximal of the anchor. The implant is advanced across the eye to the other side of the eye. The anchor is inserted into eye tissue on the other side of the eye. A therapeutic agent is eluted using the implant.
    Type: Application
    Filed: October 12, 2015
    Publication date: April 14, 2016
    Inventors: Hosheng Tu, Jason Artof, David Steven Haffner, Gregory T. Smedley, Barbara A. Niksch
  • Patent number: 9301875
    Abstract: Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: April 5, 2016
    Assignee: GLAUKOS CORPORATION
    Inventors: Hosheng Tu, Jason Artof, David Steven Haffner, Gregory T. Smedley, Barbara A. Niksch
  • Patent number: 9220632
    Abstract: Methods of treating ocular disorders are disclosed, including: inserting an implant in eye tissue, using an instrument, such that an inlet portion of the implant is in an anterior chamber of an eye and an outlet portion of the implant is in a physiological outflow pathway; removing the instrument from the eye without removing the implant; and conducting fluid comprising a therapeutic substance through the implant and into the physiological outflow pathway. Another method includes inserting an instrument into a physiologic outflow pathway through which aqueous humor drains from an anterior chamber of an eye; separating first and second walls of tissues which comprise the physiologic outflow pathway by injecting a fluid comprising a drug from the instrument while the instrument remains in the physiologic outflow pathway; and withdrawing the instrument with said fluid remaining within the eye such that the drug has a therapeutic effect on the eye.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: December 29, 2015
    Assignee: GLAUKOS CORPORATION
    Inventors: Gregory Smedley, David Haffner, Hosheng Tu