Patents by Inventor Hossam Haick

Hossam Haick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11965850
    Abstract: The present invention provides a vapor-permeable flexible sensing platform unit comprising: a first porous membrane, wherein said membrane is substantially flexible and hydrophobic; and a volatile organic compounds (VOCs) sensor disposed on said membrane, the VOCs sensor comprising an electrode array and a conducting polymer porous film being in electric contact with said electrode array, wherein the VOCs sensor is insensitive to lateral strain. Further provided are a method of preparation of said platform unit and a lift-off, float-on (LOFO) method for the preparation of protonically doped polyaniline (PANI) thin films.
    Type: Grant
    Filed: December 2, 2021
    Date of Patent: April 23, 2024
    Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
    Inventors: Hossam Haick, Weiwei Wu
  • Patent number: 11916148
    Abstract: A self-healing field-effect transistor (FET) device is disclosed in this application, the self-healing FET has a self-healing substrate, a self-healing dielectric layer, a gate electrode, at least one source electrode, at least one drain electrode, and at least one channel. The self-healing substrate and the self-healing dielectric layer have a disulfide-containing poly(urea-urethane) (PUU) polymer. The self-healing dielectric layer has a thickness of less than about 10 ?m. The electrodes have electrically conductive elongated nanostructures. The at least one channel has semi-conducting elongated nanostructures.
    Type: Grant
    Filed: December 17, 2022
    Date of Patent: February 27, 2024
    Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: Hossam Haick, Muhammad Khatib
  • Publication number: 20240044832
    Abstract: The present invention provides methods of diagnosing cancer in a test subject, comprising exposing an array of chemically sensitive sensors comprising a material selected from the group consisting of conductive nanostructures coated with an organic coating, a conducting polymer and a conductive polymer composite, to a blood sample and a urine sample obtained from the test subject, and analyzing output signals of the chemically sensitive sensors upon exposure of the array to the blood sample and the urine sample. The array of the chemically sensitive sensors can be a part of a portable medical device. Further provided is a method of diagnosing cancer in a test subject, comprising measuring and analyzing levels of a set of volatile organic compounds (VOCs) in a blood sample and a urine sample obtained from the test subject.
    Type: Application
    Filed: December 21, 2021
    Publication date: February 8, 2024
    Inventors: Hossam HAICK, Reef EINOCH AMOR, Yoav BROZA
  • Publication number: 20240043641
    Abstract: The present invention provides a composite material and a sensing platform unit comprising a self-healing polymer matrix and at least two conductive nanomaterials embedded therein. The polymer matrix has a multi-layer structure comprising a first layer comprising a network of a first nanomaterial, which resistance changes in response to a mechanical damage inflicted on the polymer matrix; and a second layer comprising a network of a second nanomaterial, configured to generate heat under applied voltage. The network of the first nanomaterial and the network of the second nanomaterial are electrically connected to a mutual control circuit which is configured to apply voltage to the second nanomaterial upon a change in resistance of the first nanomaterial. The sensing platform unit further comprises a third layer comprising a network of a third nanomaterial configured to detect at least one of pressure, strain, temperature, pH, humidity, and volatile organic compounds (VOCs).
    Type: Application
    Filed: December 15, 2021
    Publication date: February 8, 2024
    Inventors: Hossam HAICK, Muhammad KHATIB, Walaa SALIBA, Orr ZOHAR
  • Publication number: 20230337934
    Abstract: The invention concerns a sniff-on device engineered for collecting and measuring content of any gaseous sample, such as a breath or an air sample from a human or animal subject, or from an environment and determine with high accuracy at least one parameter relating to the sample content.
    Type: Application
    Filed: June 10, 2021
    Publication date: October 26, 2023
    Inventors: Hossam HAICK, Orit MAROM ALBECK, Osnat SELLA TAVOR
  • Publication number: 20230152319
    Abstract: The invention proposes an approach utilizing novel and artificially intelligent hybrid sensor arrays with multiplexed detection capabilities for disease-specific biomarkers from the exhaled breath of a subject. The technology provides a rapid and highly accurate diagnosis in various COVID-19 infection and transmission scenarios.
    Type: Application
    Filed: April 21, 2021
    Publication date: May 18, 2023
    Inventors: Hossam HAICK, Orit MAROM ALBECK, Osnat SELLA TAVOR
  • Publication number: 20230117378
    Abstract: A self-healing field-effect transistor (FET) device is disclosed in this application, the self-healing FET has a self-healing substrate, a self-healing dielectric layer, a gate electrode, at least one source electrode, at least one drain electrode, and at least one channel. The self-healing substrate and the self-healing dielectric layer have a disulfide-containing poly(urea-urethane) (PUU) polymer. The self-healing dielectric layer has a thickness of less than about 10 µm. The electrodes have electrically conductive elongated nanostructures. The at least one channel has semi-conducting elongated nanostructures.
    Type: Application
    Filed: December 17, 2022
    Publication date: April 20, 2023
    Inventors: Hossam HAICK, Muhammad KHATIB
  • Patent number: 11563122
    Abstract: The present invention provides a self-healing field-effect transistor (FET) device comprising a self-healing substrate and a self-healing dielectric layer, said substrate and said layer comprising a disulfide-containing poly(urea-urethane) (PUU) polymer, wherein the dielectric layer has a thickness of less than about 10 ?m, a gate electrode, at least one source electrode, and at least one drain electrode, said electrodes comprising electrically conductive elongated nanostructures; and at least one channel comprising semi-conducting elongated nanostructures. Further provided is a method for fabricating the FET device.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: January 24, 2023
    Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: Hossam Haick, Muhammad Khatib
  • Publication number: 20220243014
    Abstract: The present invention provides a solution-processable self-healing hydrolytically stable elastomer, a method for the preparation thereof, and articles of manufacture comprising the elastomer. The elastomer comprises polymeric chains comprising units of formula (A1), wherein R is a polybutadiene-containing polyurethane; R1 and R1? are independently selected from the group consisting of: —H, (C1-C20)alkyl, (C5-C14)aryl, —OR4, —(CO)R5, —O(CO)R6, —(SO)R7, CO—R8, —COOR9, —NO2, and halogen; R2, R2?, R3 and R3? are independently selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; R4 to R9 are the same or different, and are independently selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; m is 4; wherein the elastomer is dynamically crosslinked by aromatic disulfide metathesis, and wherein the elastomer has a water contact angle of above 100 #.
    Type: Application
    Filed: June 4, 2020
    Publication date: August 4, 2022
    Inventors: Hossam HAICK, Muhammad KHATIB
  • Patent number: 11346729
    Abstract: A pressure sensing device having a first sensing element, a second sensing element and a sensing circuit. The first and second sensing elements have one or more piezoresistive materials. The first sensing element has a first gradient along a longitudinal axis thereof having a first direction. The second sensing element has a second gradient along a longitudinal axis thereof having a second direction. The first direction of the first gradient is opposite to the second direction of the second gradient. The sensing circuit is (a) coupled to the first and second sensing elements and (b) arranged to sense at least one out of resistance and conductance of the first and second sensing elements to determine a magnitude and a location of a pressure applied on the first and second sensing elements along the longitudinal axes thereof.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: May 31, 2022
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: Hossam Haick, Meital Segev-Bar, Gady Konvalina
  • Publication number: 20220091097
    Abstract: The present invention provides a vapor-permeable flexible sensing platform unit comprising: a first porous membrane, wherein said membrane is substantially flexible and hydrophobic; and a volatile organic compounds (VOCs) sensor disposed on said membrane, the VOCs sensor comprising an electrode array and a conducting polymer porous film being in electric contact with said electrode array, wherein the VOCs sensor is insensitive to lateral strain. Further provided are a method of preparation of said platform unit and a lift-off, float-on (LOFO) method for the preparation of protonically doped polyaniline (PANI) thin films.
    Type: Application
    Filed: December 2, 2021
    Publication date: March 24, 2022
    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
    Inventors: Hossam HAICK, Weiwei Wu
  • Patent number: 11243186
    Abstract: A system having an electronic device. The electronic device has an array of chemically sensitive sensors. The sensors detect volatile organic compounds and have field effect transistors. The transistors have non-oxidized, functionalized silicon nanowires. The nanowires have surface Si atoms. The device has a plurality of functional groups that form a direct Si—C bond with the silicon nanowires, wherein Si is a surface Si atom and C is a carbon atom of the functional group. The functional groups are selected from the group consisting of: alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heterocyclyl, heteroaryl, alkylaryl, alkylalkenyl, alkylalkynyl, alkylcycloalkyl, alkylheterocyclyl and alkylheteroaryl groups, and derivatives thereof, wherein said functional groups are other than methyl and 1-butyl. The plurality of functional groups are attached to 50-100% of the surface Si atoms.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: February 8, 2022
    Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventor: Hossam Haick
  • Patent number: 11209418
    Abstract: The present invention provides a vapor-permeable flexible sensing platform unit comprising: a first porous membrane, wherein said membrane is substantially flexible and hydrophobic; and a volatile organic compounds (VOCs) sensor disposed on said membrane, the VOCs sensor comprising an electrode array and a conducting polymer porous film being in electric contact with said electrode array, wherein the VOCs sensor is insensitive to lateral strain. Further provided are a method of preparation of said platform unit and a lift-off, float-on (LOFO) method for the preparation of protonically doped polyaniline (PANI) thin films.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: December 28, 2021
    Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
    Inventors: Hossam Haick, Weiwei Wu
  • Publication number: 20210364461
    Abstract: The present invention relates to a chemically sensitive sensor for detecting volatile organic compounds, the sensor comprising a substrate, an electrode array, a micro-barrier, and a sensing layer comprising a multiplicity of core-shell particles in close-packed orientation, the particles comprising a metal nanoparticle (MNP) core and an organic ligand shell, wherein the MNP core has a mean particle size below about 15 nm. The invention further provides a method for fabrication of the chemically sensitive sensor.
    Type: Application
    Filed: October 30, 2019
    Publication date: November 25, 2021
    Inventors: Hossam HAICK, Yana MILYUTIN, Gidi SHANI, Manal ABUD HAWA
  • Patent number: 11181519
    Abstract: The present invention provides a system and method for diagnosing, screening or monitoring a disease by analyzing the breath of a test subject using a selected definitive sensor set in conjunction with a pattern recognition analyzer, wherein the pattern recognition analyzer receives output signals of the sensor set, compares them to disease-specific patterns derived from a database of response patterns of the sensor set to exhaled breath of subjects with known diseases, wherein each of the disease-specific patterns is characteristic of a particular disease, and selects a closest match between the output signals of the sensor set and the disease-specific pattern.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: November 23, 2021
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Hossam Haick, Morad Nakhleh
  • Patent number: 11129571
    Abstract: A sensing device that may include sensing elements that elements comprise a first sensing element, a second sensing element; wherein each sensing element comprises one or more piezoresistive materials; and a sensing circuit that is coupled to the sensing elements, wherein the sensing circuit is configured to sense a resistance of the first sensing element and of the second sensing element, and to determine, based on the resistance of the first sensing element and of the second sensing element, a first parameter of a cardiac waveform of a living being, wherein the cardiac waveform (a) is sensed by the first sensing element, and (ii) is not sensed by the second sensing element.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: September 28, 2021
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Hossam Haick, Meital Segev-Bar, Gady Konvalina
  • Publication number: 20210282678
    Abstract: Methods of diagnosing and/or monitoring tuberculosis (TB) in a subject by analyzing a test sample comprising at least one volatile organic compound (VOC) or semi-volatile organic compound (SVOC) emitted or excreted from the skin of the subject. The test sample can be analyzed by a sensing unit comprising nanomaterials- and/or polymer-based sensors. Further provided is a skin-mountable device comprising a fixing unit and said sensing unit. Also discloses a method of diagnosing and/or monitoring tuberculosis, comprising analyzing specific skin-emitted VOCs or SVOCs, which are indicative of tuberculosis in a subject.
    Type: Application
    Filed: March 22, 2018
    Publication date: September 16, 2021
    Inventors: Hossam HAICK, Rotem VISHINKIN
  • Publication number: 20210263050
    Abstract: The present invention provides methods of detecting cell-to-cell signaling in cancer cells and methods of diagnosing, prognosing and monitoring cancer comprising the use of volatile organic compounds, which are indicative of cell-to-cell signaling in cancer cells.
    Type: Application
    Filed: February 24, 2021
    Publication date: August 26, 2021
    Inventors: Hossam HAICK, Yoav BROZA, Mamatha SERASANAMBATI, Dina HASHOUL, Walaa SALIBA
  • Patent number: 11092563
    Abstract: The present invention provides a self-healing platform unit for pressure and analyte sensing, and a method for fabrication thereof, the platform unit comprising a self-healing substrate comprising a dynamically crosslinked polymer comprising polymeric chains and crosslinking bridges; at least one self-healing electrode comprising a non-crosslinked polymer and metal microparticles dispersed therein, wherein the at least one self-healing electrode is deposited on the substrate; and at least one sensor comprising metal nanoparticles capped with an organic coating, wherein the at least one sensor is deposited on the substrate and is in electric contact with the at least one self-healing electrode.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: August 17, 2021
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Hossam Haick, Tan-Phat Huynh
  • Publication number: 20210202748
    Abstract: The present invention provides a self-healing field-effect transistor (FET) device comprising a self-healing substrate and a self-healing dielectric layer, said substrate and said layer comprising a disulfide-containing poly(urea-urethane) (PUU) polymer, wherein the dielectric layer has a thickness of less than about 10 ?m, a gate electrode, at least one source electrode, and at least one drain electrode, said electrodes comprising electrically conductive elongated nanostructures; and at least one channel comprising semi-conducting elongated nanostructures. Further provided is a method for fabricating the FET device.
    Type: Application
    Filed: August 20, 2019
    Publication date: July 1, 2021
    Inventors: Hossam HAICK, Muhammad KHATIB