Abstract: A composition, apparatuses and a methods for collecting and detecting compounds, including but not limited to volatile organic compounds, in a human breath sample are provided. In some embodiments, there is provided a glass-wool matrix and a sorbent material distributed throughout the glass-wool matrix.

Abstract: The present invention provides a modular platform unit comprising a plurality of sensors for the combined sensing of pressure, temperature and humidity. In particular, the sensors are composed of a layer of metallic-capped nanoparticles (MCNP) casted on a flexible substrate or a rigid substrate. Integration of the platform unit for artificial or electronic skin applications is disclosed.

Abstract: The present invention provides sets of VOCs for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing breast cancer, head and neck cancer, prostate cancer or colon cancer are disclosed.

Abstract: The present invention provides a unique profile of volatile organic compounds as breath biomarkers for lung cancer. The present invention further provides the diagnosis, prognosis and monitoring of lung cancer or predicting the response to an anti-cancer treatment through the detection of the unique profile of volatile organic compounds indicative of lung cancer at its various stages.

Abstract: The present invention provides a system and method for diagnosing, monitoring or prognosing Alzheimer's disease using at least one sensor comprising carbon nanotubes coated with cyclodextrin or derivatives thereof and/or at least one sensor comprising metal nanoparticles coated with various organic coatings in conjunction with a learning and pattern recognition algorithm.

Abstract: The present invention provides a system and method for diagnosing, monitoring, prognosing or staging Parkinson's disease using at least one sensor comprising carbon nanotubes coated with cyclodextrin or derivatives thereof or metal nanoparticles coated with various organic coatings in conjunction with a learning and pattern recognition algorithm.

Abstract: The present invention provides methods of identifying a genetic abnormality such as mutation in EGFR or KRAS or ALK which is associated with the management of lung cancer or diagnosing, prognosing or monitoring the treatment of pre-cancerous conditions of the lung, such as bronchial dysplasia or atypical alveolar hyperplasia (AAH), through the detection of at least one volatile organic compound indicative of these states.

Abstract: A sensor technology comprising a single nano-material (gold nanoparticles and/or carbon nanotube) based sensor or a plurality of sensors in conjunction with a pattern recognition algorithm for non-invasive and accurate diagnosis of tuberculosis caused by M. tuberculosis bacteria in a subject. The sensor technology is suitable for population screening of tuberculosis, particularly in resource-poor and developing countries.

Abstract: The present invention provides a sensor apparatus based on 2D films or 3D assemblies of cubic nanoparticles capped with an organic coating. The apparatus is used to determine the composition and preferably measure the concentration of volatile and non-volatile compounds in a sample, with very high sensitivity. Methods for use of the apparatus in applications such as diagnosis of disease, food quality and environmental control are disclosed.

Abstract: The present invention provides a modular platform unit comprising a plurality of sensors for the combined sensing of pressure, temperature and humidity. In particular, the sensors are composed of a layer of metallic-capped nanoparticles (MCNP) casted on a flexible substrate or a rigid substrate. Integration of the platform unit for artificial or electronic skin applications is disclosed.

Abstract: The present invention provides a system and method for diagnosing, monitoring or prognosing Multiple Sclerosis at different stages as well as affording the prediction of disease activity and response to a treatment regimen, using at least one sensor comprising carbon nanotubes or metal nanoparticles, each coated with various organic coatings in conjunction with a pattern recognition algorithm.

Abstract: The present application describes a sensor apparatus, especially an electronic nose, based on 2D films or 3D assemblies of cubic nanoparticles capped with an organic coating. The organic coating is modified with unique compositions of functional moieties, e.g. cyclodextrins, to provide the detection of volatile and non-volatile compounds derived from explosive materials, e.g. PETN, RDX, TNT etc. with very high sensitivity. The nose employs pattern recognition algorithms and methods, e.g. PCA, for detecting and quantifying specific explosive compounds.

Abstract: A device having a nano-wire array and a method for manufacturing an array of nano-wires. The method includes spraying on a substrate droplets of a suspension that comprises nano-wires and at least a partially volatile solvent; and evaporating the at least partially volatile solvent of the droplets to form the array of nano-wires. At least one of the spraying and the evaporating comprises executing at least one aggregation reduction measure for limiting a formation of three dimensional aggregations of nano-wires on the substrate.

Abstract: A set of volatile organic compounds is provided, comprising at least butylated hydroxy toluene or 4,6-di (1,1-dimethylethyl)-2-methyl-phenol for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing lung cancer are also disclosed.

Abstract: The present invention provides a sensor or a system comprising gold nanoparticles coated with specific organic coatings for diagnosing, staging or monitoring chronic kidney disease.

Abstract: The present invention provides a system containing an array of chemically sensitive sensors based on coated single walled carbon nanotubes, for measuring volatile organic compounds indicative of renal failure. Methods of breath analysis for diagnosing chronic, acute and end-stage renal failure are disclosed.

Abstract: The present invention provides methods of identifying a genetic abnormality such as mutation in EGFR or KRAS or ALK which is associated with the management of lung cancer or diagnosing, prognosing or monitoring the treatment of pre-cancerous conditions of the lung, such as bronchial dysplasia or atypical alveolar hyperplasia (AAH), through the detection of at least one volatile organic compound indicative of these states.

Abstract: The present invention provides a method for detecting and grading benign and malignant tumors using at least one sensor of conductive nanoparticles capped with an organic coating in conjunction with a learning and pattern recognition algorithm. The method utilizes a plurality of response induced parameters to obtain improved sensitivity and selectivity for diagnosis, prognosis, monitoring and staging various types of cancers, or for identifying or grading benign or malignant tumors.

Abstract: The present invention provides a system and method for diagnosing, monitoring or prognosing Multiple Sclerosis at different stages as well as affording the prediction of disease activity and response to a treatment regimen, using at least one sensor comprising carbon nanotubes or metal nanoparticles, each coated with various organic coatings in conjunction with a pattern recognition algorithm.

Abstract: The present invention provides a system for measuring biomarker analytes indicative of various diseases comprising an array of sensors sensitive to volatile organic compounds. Particularly, the system is composed of a random network of single-walled carbon nanotubes (SWCNTs) coated with non-polar small organic molecules in conjunction with learning and pattern recognition algorithms. Methods of discriminating between breath samples of healthy individuals and of lung cancer patients are disclosed.