Patents by Inventor Houxing Fan

Houxing Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AURORA KINASE INHIBITORS AND USES THEREOF
    Publication number: 20210198261
    Abstract: The invention relates to a type of novel pyridine compound and a preparation method and application thereof. Specifically, the invention relates to a compound of formula (1) and a preparation method thereof, and an application of the compound of formula (1) and pharmaceutically acceptable salts thereof as aurora kinase inhibitors in preparation of anti-tumor drugs.
    Type: Application
    Filed: March 14, 2021
    Publication date: July 1, 2021
    Inventors: Yuli XIE, Houxing FAN
  • ACRYLOYL-CONTAINING NUCLEAR TRANSPORT REGULATORS AND USES THEREOF
    Publication number: 20210053945
    Abstract: The invention relates to a series of novel compounds containing acryloyl group. In particular, the invention relates to acryloyl group-containing compounds shown in formula (1) and the preparation method thereof, and application of the compounds shown in formula (1) and pharmaceutically acceptable salts thereof in preparation of medicaments for treating, regulating and/or preventing diseases related to physiological conditions related to CRM1 protein.
    Type: Application
    Filed: October 15, 2020
    Publication date: February 25, 2021
    Inventors: Houxing FAN, Yuli XIE
  • Nitroimidazole Compound, Preparation Method Therefor And Use Thereof In Drug Manufacturing
    Publication number: 20170334927
    Abstract: A nitroimidazole compound represented by general formula (I) or an optical isomer thereof or a pharmaceutically acceptable salt thereof, and a preparation method therefore, and use thereof in manufacturing drugs for the treating infectious diseases caused by mycobacterium tuberculosis. Specific groups in general formula (I) are as defined in the specification.
    Type: Application
    Filed: December 11, 2015
    Publication date: November 23, 2017
    Applicant: Shanghai Sun-Sail Pharmaceutical Science & Technology Co., Ltd.
    Inventors: Chuansheng Zhao, Bingbin Zhang, Tongrui Zhou, Tiancai Wang, Jun Sun, Houxing Fan
  • (6,7-dihydro-2-nitro-5H-imidazol[2,1-b][1,3]oxazin-6-yl) amide compounds, preparation methods and uses thereof
    Patent number: 8563547
    Abstract: (6,7-Dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)amide compounds of formula (I), and their pharmaceutically acceptable salts, preparation methods and pharmaceutical compositions thereof are disclosed, wherein m and R are defined as in the description. The uses of the compounds in preparing medicaments for treating infectious diseases caused by Mycobacterium tuberculosis, especially infectious diseases caused by multi-drug resistance Mycobacterium tuberculosi are also disclosed.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: October 22, 2013
    Assignee: Shanghai Sun-Sail Pharmaceutical Science & Technology Co., Ltd.
    Inventors: Tiancai Wang, Ting Xin, Houxing Fan, Yilang Chen
  • Benzoxazine oxazolidinone compounds, preparation methods and uses thereof
    Patent number: 8507481
    Abstract: Novel benzoxazine oxazolidinone compounds, preparation methods and uses thereof are disclosed, which belong to the field of pharmacy. More specifically, novel benzoxazine oxazolidinone compounds represented by the following general formula (I), preparation methods and uses thereof in preparing medicament for treating infectious diseases, especially infectious diseases caused by multi-drug resistant bacteria, are disclosed.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: August 13, 2013
    Assignees: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Nanjing Changao Pharmaceutical Science & Technology Co., Limited
    Inventors: Yushe Yang, Qisheng Xin, Houxing Fan, Bin Guo, Xin Liu, Huili He, Wei Li, Zhan Li
  • (6,7-DIHYDRO-2-NITRO-5H-IMIDAZOL[2,1-B][1,3]OXAZIN-6YL) AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF
    Publication number: 20130143864
    Abstract: (6,7-Dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)amide compounds of formula (I), and their pharmaceutically acceptable salts, preparation methods and pharmaceutical compositions thereof are disclosed, wherein m and R are defined as in the description. The uses of the compounds in preparing medicaments for treating infectious diseases caused by Mycobacterium tuberculosis, especially infectious diseases caused by multi-drug resistance Mycobacterium tuberculosi are also disclosed.
    Type: Application
    Filed: October 26, 2012
    Publication date: June 6, 2013
    Inventors: Tiancai Wang, Ting Xin, Houxing Fan, Yilang Chen
  • NOVEL BENZOXAZINE OXAZOLIDINONE COMPOUNDS, PREPARATION METHODS AND USES THEREOF
    Publication number: 20130123249
    Abstract: Novel benzoxazine oxazolidinone compounds, preparation methods and uses thereof are disclosed, which belong to the field of pharmacy. More specifically, novel benzoxazine oxazolidinone compounds represented by the following general formula (I), preparation methods and uses thereof in preparing medicament for treating infectious diseases, especially infectious diseases caused by multi-drug resistant bacteria, are disclosed.
    Type: Application
    Filed: May 12, 2011
    Publication date: May 16, 2013
    Inventors: Yushe Yang, Qisheng Xin, Houxing Fan, Bin Guo, Xin Liu, Huili He, Wei Li, Zhan Li