Patents by Inventor Hsien-Yeh Chen

Hsien-Yeh Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150191628
    Abstract: The present invention provides a method of forming N-hydroxysuccinimide ester-functionalized paracyclophane. The present method is carried out by adding 4-carboxyl-paracyclophane into N,N?-Dicyclohexylcarbodiimide (DCC) and N-Hydroxysuccinimide (NHS) to form N-hydroxysuccinimide ester-functionalized paracyclophane. The present invention further provides a chemical film on a substrate and a method of forming the same, wherein the chemical film includes N-hydroxysuccinimide ester-functionalized poly-para-xylylene.
    Type: Application
    Filed: April 30, 2014
    Publication date: July 9, 2015
    Inventor: Hsien-Yeh Chen
  • Publication number: 20140220496
    Abstract: A method for forming a photoresist structure is provided The method includes the step of forming a photoresist layer on a substrate, the step of exposing a portion of the photoresist layer to form an exposed portion of the photoresist layer, and the step of removing the photoresist layer except the exposed portion with a solvent, so as to form the photoresist structure, wherein the photoresist layer has a polymer having a structure represented by formula (I). The method of the present invention can generate a photoresist with an even thickness on devices with complex geometries or three-dimensional substrates. Thus, it can be applied to tissue engineering scaffolds, three-dimensional cell cultivation system and novel bio-microelectromechnical elements.
    Type: Application
    Filed: September 10, 2013
    Publication date: August 7, 2014
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Hsien-Yeh Chen, Mu-Gi Wu, Chieh-Chen Hsieh, Hung-Lun Hsu, Kai-Wen Hsiao
  • Publication number: 20140199470
    Abstract: Provided are a polymer composition on a substrate and a surface modification method which is non-selective to substrate materials. Chemical vapor deposition polymerization is used to deposit a maleimide-functionalized poly-p-xylylene coating on a substrate. The substrate is readily available to perform a thiol-maleimide coupling reaction under mild conditions so as to modify the surface thereof. Furthermore, through a tailored thiol-terminal molecule, a designer surface can be created via thiol-maleimide coupling on a substrate, and the resulting surface can exhibit various desired biological functions for biotechnological applications. Therefore, this modification technique can be applied to biological fields extensively.
    Type: Application
    Filed: March 15, 2013
    Publication date: July 17, 2014
    Applicant: National Taiwan University
    Inventors: Hsien-Yeh Chen, Sheng-Tung Huang, Meng-Yu Tsai
  • Patent number: 7947148
    Abstract: Methods for bonding include deposition an adhesion layer on at least one substrate using chemical vapor deposition. The two adhesion layers each have a reactive group that is complementary to the other, thus enabling strong adhesion between the bonded substrates. Devices include two substrates that can be adhered together by chemically depositing an adhesion layer on at least one substrate using chemical vapor deposition. The substrates each have a reactive group that is complementary to the other, thus enabling strong adhesion between the bonded substrates.
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: May 24, 2011
    Assignee: The Regents of the University of Michigan
    Inventors: Joerg Lahann, Hsien-Yeh Chen
  • Patent number: 7909928
    Abstract: Reactive polymer coatings that undergo regioselective reactions with target biomolecules are provided. The polymers of the coatings are deposited via chemical vapor deposition and comprise one or more functional groups that exhibit regioselective bonding with a functional group or a target molecule. Such polymers include poly-xylylenes having functional groups such as alkynes or azides. The regioselective bonding of the reactive polymers provide stable immobilization of target molecules and/or ligands and can create biofunctional surfaces having a wide range of applications.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: March 22, 2011
    Assignee: The Regents of The University of Michigan
    Inventors: Joerg Lahann, Himabindu Nandivada, Hsien-Yeh Chen
  • Publication number: 20070281126
    Abstract: Methods for bonding include deposition an adhesion layer on at least one substrate using chemical vapor deposition. The two adhesion layers each have a reactive group that is complementary to the other, thus enabling strong adhesion between the bonded substrates. Devices include two substrates that can be adhered together by chemically depositing an adhesion layer on at least one substrate using chemical vapor deposition. The substrates each have a reactive group that is complementary to the other, thus enabling strong adhesion between the bonded substrates.
    Type: Application
    Filed: June 1, 2007
    Publication date: December 6, 2007
    Applicant: The Regents of the University of Michigan
    Inventors: Joerg Lahann, Hsien-Yeh Chen
  • Publication number: 20070272122
    Abstract: Reactive polymer coatings that undergo regioselective reactions with target biomolecules are provided. The polymers of the coatings are deposited via chemical vapor deposition and comprise one or more functional groups that exhibit regioselective bonding with a functional group or a target molecule. Such polymers include poly-xylylenes having functional groups such as alkynes or azides. The regioselective bonding of the reactive polymers provide stable immobilization of target molecules and/or ligands and can create biofunctional surfaces having a wide range of applications.
    Type: Application
    Filed: March 26, 2007
    Publication date: November 29, 2007
    Inventors: Joerg Lahann, Himabindu Nandivada, Hsien-Yeh Chen