Abstract: A semiconductor device includes a semiconductor layer and a gate structure on the semiconductor layer. The gate structure includes a multi-stepped gate dielectric on the semiconductor layer and a gate electrode on the multi-stepped gate dielectric. The multi-stepped gate dielectric includes a first gate dielectric segment having a first thickness and a second gate dielectric segment having a second thickness that is less than the first thickness.

Abstract: Provided are monospecific and bispecific proteins that bind specifically to OX40 and/or PD-L1. Exemplary proteins release the inhibition through PD-L1 and stimulate T cell through OX40. Exemplary polyvalent proteins comprise at least one OX40 binding site and at least one PD-L1 binding site. In certain embodiments, the binding sites may be linked through an immunoglobulin constant region. Anti-OX40 and anti-PD-L1 antibodies are also provided.

Abstract: Provided are monospecific and bispecific proteins that bind specifically to OX40 and/or PD-L1. Exemplary proteins release the inhibition through PD-L1 and stimulate T cell through OX40. Exemplary polyvalent proteins comprise at least one OX40 binding site and at least one PD-L1 binding site. In certain embodiments, the binding sites may be linked through an immunoglobulin constant region. Anti-OX40 and anti-PD-L1 antibodies are also provided.

Abstract: A slicing method for horizontal facets of color 3D object includes following steps: executing a slicing procedure; calculating an intersection (4) of any polygon facet (3) of a color 3D object with one of a plurality of slicing planes (2); determining whether the polygon facet (3) is a horizontal facet; determining whether the slicing plane (2) currently processed is a highest slicing plane intersecting with the polygon facet (3) if the polygon facet (3) is determined as a horizontal facet; calculating another intersection (4) of the polygon facet (3) with next slicing plane (2) if the slicing plane (2) currently processed is not the highest slicing plane; performing a pixelated procedure to the polygon facet (3) for generating pixelated color data (5) if the slicing plane (2) currently processed is the highest slicing plane; and storing the pixelated color data (5) to a slicing file of the highest slicing plane.

Abstract: A printing method for color compensation adopted by a 3D printer (1) having a 3D nozzle (121) and a 2D nozzle (122) is disclosed. The printing method includes following steps of: controlling the 3D nozzle (121) to print a slicing object (2) of the 3D object upon a printing platform (11) according to a route file; controlling the 2D nozzle (122) to perform coloring on the printed slicing object (2) according to an image file; controlling the 2D nozzle (122) and the printing platform (1) to rotate relatively for creating an angular transposition between the 2D nozzle (122) and the printing platform (1) after the slicing object (2) is colored completely; and, controlling the 2D nozzle (122) to again perform coloring on the colored slicing object (2) after the 2D nozzle (2) and the printing platform (11) rotated relatively.

Abstract: A 3D slicing and printing method using strengthened auxiliary wall is provided. The method is to control a 3D printer (3) to retrieve multiple layers of object print data corresponding to a 3D object (90), and multiple layers of wall print data and raft print data, print multiple layers of raft slice physical models (400,60) on a print platform (307) layer by layer according to the raft print data, print multiple layers of wall slice physical models (420-421,80-81) on the printed raft slice physical models (400,60) layer by layer according to the wall print data, and print multiple layers of 3D slice physical models (50-53,70-71) layer by layer according to the object print data during printing the raft slice physical models (400,60) and the wall slice physical models (420-421,80-81). It can effectively prevent the auxiliary wall (42,8) from collapsing and failure of printing a whole 3D physical model (5,7) via making a raft structure (40,6) be arranged under the auxiliary wall (42,8).

Abstract: Provided are monospecific and bispecific proteins that bind specifically to OX40 and/or PD-L1. Exemplary proteins release the inhibition through PD-L1 and stimulate T cell through OX40. Exemplary polyvalent proteins comprise at least one OX40 binding site and at least one PD-L1 binding site. In certain embodiments, the binding sites may be linked through an immunoglobulin constant region. Anti-OX40 and anti-PD-L1 antibodies are also provided.

Abstract: The inkjet position adjustment method includes the following steps. A three-dimensional digital model is obtained, and a slicing processing is performed on the three-dimensional digital model to generate a layer object having a cross-sectional contour. A normal direction of an object surface corresponding to the layer object is obtained from the three-dimensional digital model. When the normal direction points to a negative direction of a first axis, a surface tilt degree of the object surface corresponding to the layer object is obtained, and an inner-shift amount of an inkjet position of the layer object is calculated according to the surface tilt degree. An inkjet region of the layer object is obtained according to the inner-shift amount and the cross-sectional contour. After controlling a print module to print the layer object, an inkjet module is controlled to inject ink on the layer object according to the inkjet region.

Abstract: A three dimensional printing method and a three dimensional printing apparatus are provided. Layer information of a three dimensional object is obtained, wherein the three dimensional object includes at least one layer object and the layer information includes a plurality of coordinate point locations of the at least one layer object. A geometry parameter is calculated according to the coordinate point locations, and whether the layer object includes at least one small-area object is determined according to the geometry parameter. If the layer object includes the at least one small-area object, a feed-material output amount associated with the small-area object is reduced. A printing module is controlled to print the small-area object according to the reduced feed-material output amount.

Abstract: A processor imports a 3D object, performs a 3D route slicing on the 3D object for generating printing routes respectively corresponding to printing layers of the 3D object, and performs a 2D image slicing on the 3D object for generating image files corresponding to each printing layer. The processor stores one printing route of one printing layer into a route file; stores a jetting command of the image files of the same printing layer into the route file; and stores a jetting route of the same printing layer into the route file. The processor, according to a slicing order of the multiple printing layers, stores the printing route, the jetting command, and the jetting route of each printing layer respectively into the route file, so as to complete record the route file and then outputs the route file and the multiple image files.

Abstract: A three dimensional printing apparatus and a controlling method thereof are provided. A first forming material and a second forming material are adapted for being fed into a melting nozzle. A controller determines a first pulling-back amount according to a first feeding-in ratio of the first forming material and determines a second pulling-back amount according to a second feeding-in ratio of the second forming material. During a period in which a printing module stops extruding any material, the controller controls a feeding module to pull back the first forming material along a direction which is departing from a melting nozzle and controls the feeding module to pull back the second forming material along the direction which is departing from the melting nozzle.

Abstract: An inkjet width adjustment method adapting to three-dimensional printing equipment is provided. The method in one of exemplary embodiments is provided hereafter. A three-dimensional digital model is obtained, and a slicing procedure is performed on the three-dimensional digital model to produce a layer object, wherein the layer object has a cross-sectional contour. A surface tilt degree corresponding to the cross-sectional contour is obtained from the three-dimensional digital model, and an ideal inkjet width of the layer object is calculated according to the surface tilt degree corresponding to the cross-sectional contour. After a print module is controlled to print the layer object, an inkjet module is controlled to spray ink along the cross-sectional contour of the layer object according to the ideal inkjet width. In addition, the three-dimensional printing equipment is also provided.

Abstract: A three-dimensional (3-D) printing apparatus and an inkjet coloring method thereof are provided. The 3-D printing apparatus includes a platform, a three-dimensional printing head, an inkjet head and the method includes following steps. A layer thickness of at least one layer object forming a 3-D object is obtained. An ink discharge volume of an ink layer is adjusted according to the layer thickness, wherein the ink discharge volume is in positive correlation with the layer thickness. A building material is melted and printed out on the platform according to the layer thickness by the three-dimensional printing head to form the at last one layer object. Ink is dispensed on the at last one layer object according to the adjusted ink discharge volume by the inkjet head to form the ink layer.

Abstract: A three-dimensional printing method and a three-dimensional printing device are provided. The three-dimensional printing method includes the following steps: obtaining printing information of a plurality of sliced objects and determine an top surface area of the three-dimensional object according to the printing information; obtaining first printing information of the top surface area in the printing information; driving a nozzle module according to the printing information to print the three-dimensional object. In the process of printing the three-dimensional object, the method further includes: driving the nozzle module to move above the top surface area again according to the first printing information to heat a plurality of printing materials located on the top surface area after the top surface area is printed such that the plurality of printing materials are heated to a molten state to fill gaps between the plurality of printing materials.

Abstract: An inkjet position adjustment method and a three-dimensional printing equipment are provided. The inkjet position adjustment method includes the following steps. A three-dimensional digital model is obtained, and a slicing processing is performed on the three-dimensional digital model to generate a layer object having a cross-sectional contour. A normal direction of an object surface corresponding to the layer object is obtained from the three-dimensional digital model. When the normal direction points to a negative direction of a first axis, a surface tilt degree of the object surface corresponding to the layer object is obtained, and an inner-shift amount of an inkjet position of the layer object is calculated according to the surface tilt degree. An inkjet region of the layer object is obtained according to the inner-shift amount and the cross-sectional contour.

Abstract: An inkjet width adjustment method adapting to three-dimensional printing equipment is provided. The method in one of exemplary embodiments is provided hereafter. A three-dimensional digital model is obtained, and a slicing procedure is performed on the three-dimensional digital model to produce a layer object, wherein the layer object has a cross-sectional contour. A surface tilt degree corresponding to the cross-sectional contour is obtained from the three-dimensional digital model, and an ideal inkjet width of the layer object is calculated according to the surface tilt degree corresponding to the cross-sectional contour. After a print module is controlled to print the layer object, an inkjet module is controlled to spray ink along the cross-sectional contour of the layer object according to the ideal inkjet width. In addition, the three-dimensional printing equipment is also provided.

Abstract: A method for three dimensional (3D) printing and a 3D printing device are provided. The 3D printing device includes a modeling printing head, a coloring printing head, and a platform. The modeling printing head and the coloring printing head are co-constructed. The three dimensional printing method includes: printing a forming layer and at least one material barrier outside a bounding area of the forming layer; calculating multiple coloring routes of the coloring printing head according to an edge of the forming layer; converting the coloring routes of the coloring printing head into multiple color-passing routes of the modeling printing head; calculating multiple detour routes of the modeling printing head according to the color-passing routes of the modeling printing head.

Abstract: A processor imports a 3D object, performs a 3D route slicing on the 3D object for generating printing routes respectively corresponding to printing layers of the 3D object, and performs a 2D image slicing on the 3D object for generating image files corresponding to each printing layer. The processor stores one printing route of one printing layer into a route file; stores a jetting command of the image files of the same printing layer into the route file; and stores a jetting route of the same printing layer into the route file. The processor, according to a slicing order of the multiple printing layers, stores the printing route, the jetting command, and the jetting route of each printing layer respectively into the route file, so as to complete record the route file and then outputs the route file and the multiple image files.

Abstract: A three dimension (3D) printing coloring method and a 3D printing system are provided. The method includes: generating printing object information according to model information of a 3D object, where the printing object information includes first contour coloring information and second contour coloring information; determining whether a similarity degree of the first contour coloring information and the second contour coloring information conforms to a default condition; if the similarity degree conforms to the default condition, controlling, according to the first contour coloring information and the second contour coloring information, a 3D printing device to perform a simultaneous coloring operation on a first printing layer and a second printing layer of a 3D object. Therefore, a working efficiency of the 3D printing device can be improved.

Abstract: A method for printing a model for a 3D printer includes: perform a slicing process on an outer-frame object for generating multiple slicing-route files of multiple printing layers; perform the slicing process on a modeling object for generating multiple inkjet graphic files of the multiple printing layers; print a slicing object of one printing layer according to corresponding one of the slicing-route files; perform a filling process to the inside of the printed slicing object; perform a coloring process on the inside of the printed slicing object according to one of the inkjet graphic files corresponding to the same printing layer; and re-execute the above printing steps until all the printing layers are printed. The inside of the 3D model is colored via the inkjet graphic files generated after processing on the modeling object generating the visual effect that the modeling object is accommodated within the 3D model.